Personal information

Activities

Employment (8)

University of Memphis: Memphis, TN, US

2019-05-01 to present | Dean (College of Arts and Sciences)
Employment
Source: Self-asserted source
Abby Parrill

University of Memphis: Memphis, TN, US

2006-09-01 to present | Professor (Chemistry)
Employment
Source: Self-asserted source
Abby Parrill

University of Memphis: Memphis, TN, US

2019-02-01 to 2019-04-30 | Interim Dean (College of Arts and Sciences)
Employment
Source: Self-asserted source
Abby Parrill

University of Memphis: Memphis, TN, US

2014-09-01 to 2019-01-31 | Associate Dean (College of Arts and Sciences)
Employment
Source: Self-asserted source
Abby Parrill

University of Memphis: Memphis, TN, US

2010-01-01 to 2014-08-31 | Chair (Chemistry)
Employment
Source: Self-asserted source
Abby Parrill

University of Memphis: Memphis, TN, US

2002-09-01 to 2006-08-31 | Associate Professor (Chemistry)
Employment
Source: Self-asserted source
Abby Parrill

University of Memphis: Memphis, TN, US

1998-07-01 to 2002-08-31 | Assistant Professor (Chemistry)
Employment
Source: Self-asserted source
Abby Parrill

Michigan State University: East Lansing, MI, US

1996-07-06 to 1998-06-30 | Lumsden-Valrance Lecturer (Chemistry)
Employment
Source: Self-asserted source
Abby Parrill

Education and qualifications (3)

University of Arizona: Tucson, AZ, US

1996-08 | Ph.D. (Chemistry)
Education
Source: Self-asserted source
Abby Parrill

University of Arizona: Tucson, AZ, US

1996-05 | M.S. (Chemistry)
Education
Source: Self-asserted source
Abby Parrill

Central Michigan University: Mt. Pleasant, MI, US

1992-08 | B.S. (Chemistry)
Education
Source: Self-asserted source
Abby Parrill

Professional activities (5)

University of Memphis Alumni Association: Memphis, TN, US

2017 | Willard R. Sparks Eminent Faculty Award
Distinction
Source: Self-asserted source
Abby Parrill

University of Memphis Alumni Foundation: Memphis, TN, US

2011 | Distinguished Research in Science, Engineering and Mathematics
Distinction
Source: Self-asserted source
Abby Parrill

University of Memphis: Memphis, TN, US

2008 | Distinguished Research Award (College of Arts and Sciences)
Distinction
Source: Self-asserted source
Abby Parrill

University of Memphis: Memphis, TN, US

2007 | Olin Atkins Professorship
Distinction
Source: Self-asserted source
Abby Parrill

University of Memphis: Memphis, TN, US

2000 | Early Career Research Award (College of Arts and Sciences)
Distinction
Source: Self-asserted source
Abby Parrill

Works (50 of 109)

Items per page:
Page 1 of 3

G Protein-Coupled Receptor–Ligand Pose and Functional Class Prediction

International Journal of Molecular Sciences
2024-06-22 | Journal article
Contributors: Gregory L. Szwabowski; Makenzie Griffing; Elijah J. Mugabe; Daniel O’Malley; Lindsey N. Baker; Daniel L. Baker; Abby L. Parrill
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Structure-based pharmacophore modeling 2. Developing a novel framework for structure-based pharmacophore model generation and selection

Journal of Molecular Graphics and Modelling
2023-07 | Journal article
Contributors: Gregory L. Szwabowski; Bernie J. Daigle, Jr.; Daniel L. Baker; Abby L. Parrill
Source: check_circle
Crossref

Application of computational methods for class A GPCR Ligand discovery

Journal of Molecular Graphics and Modelling
2023-06 | Journal article
Contributors: Gregory L. Szwabowski; Daniel L. Baker; Abby L. Parrill
Source: check_circle
Crossref

Structure-based pharmacophore modeling 1. Automated random pharmacophore model generation

Journal of Molecular Graphics and Modelling
2023-06 | Journal article
Contributors: Gregory L. Szwabowski; Judith A. Cole; Daniel L. Baker; Abby L. Parrill
Source: check_circle
Crossref

Self-docking and cross-docking simulations of G protein-coupled receptor-ligand complexes: Impact of ligand type and receptor activation state

Journal of Molecular Graphics and Modelling
2022-05 | Journal article
Contributors: Brittany N. Thomas; Abby L. Parrill; Daniel L. Baker
Source: check_circle
Crossref

Ligand-based G Protein Coupled Receptor pharmacophore modeling: Assessing the role of ligand function in model development

Journal of Molecular Graphics and Modelling
2022-03 | Journal article
Contributors: P. Castleman; G. Szwabowski; D. Bowman; J. Cole; A.L. Parrill; D.L. Baker
Source: check_circle
Crossref

Molecular modelling guided design, synthesis and QSAR analysis of new small molecule non-lipid autotaxin inhibitors

Bioorganic Chemistry
2020 | Journal article
EID:

2-s2.0-85090037623

Part of ISBN:

10902120 00452068

Contributors: Banerjee, S.; Norman, D.D.; Deng, S.; Fakayode, S.O.; Lee, S.C.; Parrill, A.L.; Li, W.; Miller, D.D.; Tigyi, G.J.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Optical Control of Lysophosphatidic Acid Signaling

Journal of the American Chemical Society
2020 | Journal article
EID:

2-s2.0-85086624889

Part of ISBN:

15205126 00027863

Contributors: Morstein, J.; Dacheux, M.A.; Norman, D.D.; Shemet, A.; Donthamsetti, P.C.; Citir, M.; Frank, J.A.; Schultz, C.; Schultz, C.; Isacoff, E.Y. et al.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Benchmarking GPCR homology model template selection in combination with de novo loop generation

Journal of Computer-Aided Molecular Design
2020-10-31 | Journal article
Contributors: Gregory L. Szwabowski; Paige N. Castleman; Chandler K. Sears; Lee H. Wink; Judith A. Cole; Daniel L. Baker; Abby L. Parrill
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

GPCR homology model template selection benchmarking: Global versus local similarity measures

Journal of Molecular Graphics and Modelling
2019 | Journal article
EID:

2-s2.0-85055755238

Part of ISBN:

18734243 10933263

Contributors: Castleman, P.N.; Sears, C.K.; Cole, J.A.; Baker, D.L.; Parrill, A.L.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Optical control of sphingosine-1-phosphate formation and function

Nature Chemical Biology
2019 | Journal article
EID:

2-s2.0-85065156504

Part of ISBN:

15524469 15524450

Contributors: Morstein, J.; Hill, R.Z.; Novak, A.J.E.; Feng, S.; Norman, D.D.; Donthamsetti, P.C.; Frank, J.A.; Harayama, T.; Williams, B.M.; Parrill, A.L. et al.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

A benchmark study of loop modeling methods applied to G protein-coupled receptors

Journal of Computer-Aided Molecular Design
2019-06-23 | Journal article
Contributors: Lee H. Wink; Daniel L. Baker; Judith A. Cole; Abby L. Parrill
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

G protein-coupled receptors: The evolution of structural insight

AIMS Biophysics
2017 | Journal article
EID:

2-s2.0-85050855936

Part of ISBN:

23779098

Contributors: Gacasan, S.B.; Baker, D.L.; Parrill, A.L.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Highly Potent Non-Carboxylic Acid Autotaxin Inhibitors Reduce Melanoma Metastasis and Chemotherapeutic Resistance of Breast Cancer Stem Cells

Journal of Medicinal Chemistry
2017 | Journal article
EID:

2-s2.0-85013834676

Part of ISBN:

15204804 00222623

Contributors: Banerjee, S.; Norman, D.D.; Lee, S.C.; Parrill, A.L.; Pham, T.C.T.; Baker, D.L.; Tigyi, G.J.; Miller, D.D.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Discovery and synthetic optimization of a novel scaffold for hydrophobic tunnel-targeted autotaxin inhibition

Bioorganic and Medicinal Chemistry
2016 | Journal article
EID:

2-s2.0-84985995464

Part of ISBN:

14643391 09680896

Contributors: Ragle, L.E.; Palanisamy, D.J.; Joe, M.J.; Stein, R.S.; Norman, D.D.; Tigyi, G.; Baker, D.L.; Parrill, A.L.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Preface

Reviews in Computational Chemistry
2016 | Book
EID:

2-s2.0-85019562987

Contributors: Parrill, A.L.; Lipkowitz, K.B.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Reprint of: "synthetic lipids and their role in defining macromolecular assemblies"

Chemistry and Physics of Lipids
2016 | Journal article
EID:

2-s2.0-84954220627

Part of ISBN:

18732941 00093084

Contributors: Parrill, A.L.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Reviews in Computational Chemistry

Reviews in Computational Chemistry
2016 | Book
EID:

2-s2.0-85015134200

Contributors: Parrill, A.L.; Lipkowitz, K.B.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Erratum: Multi-generational pharmacophore modeling for ligands to the cholane steroid-recognition site in the β<inf>1</inf> modulatory subunit of the BK<inf>Ca</inf> channel (J. Mol. Graph. Model. (2014) 54 (174-183) DOI: 10.1016/j.jmgm.2014.10.008)

Journal of Molecular Graphics and Modelling
2015 | Journal article
EID:

2-s2.0-84951569604

Part of ISBN:

18734243 10933263

Contributors: McMillan, J.E.; Bukiya, A.N.; Terrell, C.L.; Patil, S.A.; Miller, D.D.; Dopico, A.M.; Parrill, A.L.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Preface

Reviews in Computational Chemistry
2015 | Book
EID:

2-s2.0-85015902399

Contributors: Parrill, A.L.; Lipkowitz, K.B.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Reviews in Computational Chemistry

Reviews in Computational Chemistry
2015 | Book
EID:

2-s2.0-85015909191

Contributors: Parrill, A.L.; Lipkowitz, K.B.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Synthetic lipids and their role in defining macromolecular assemblies

Chemistry and Physics of Lipids
2015 | Journal article
EID:

2-s2.0-84940043803

Part of ISBN:

18732941 00093084

Contributors: Parrill, A.L.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Activation of calcium- and voltage-gated potassium channels of large conductance by leukotriene B4

Journal of Biological Chemistry
2014 | Journal article
EID:

2-s2.0-84919482912

Part of ISBN:

1083351X 00219258

Contributors: Bukiya, A.N.; McMillan, J.; Liu, J.; Shivakumar, B.; Parrill, A.L.; Dopico, A.M.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Design of anticancer lysophosphatidic acid agonists and antagonists

Future Medicinal Chemistry
2014 | Journal article
EID:

2-s2.0-84903280095

Part of ISBN:

17568927 17568919

Contributors: Parrill, A.L.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Multi-generational pharmacophore modeling for ligands to the cholane steroid-recognition site in the β<inf>1</inf> modulatory subunit of the BK<inf>Ca</inf> channel

Journal of Molecular Graphics and Modelling
2014 | Journal article
EID:

2-s2.0-84910124565

Part of ISBN:

18734243 10933263

Contributors: McMillan, J.E.; Bukiya, A.N.; Terrell, C.L.; Patil, S.A.; Miller, D.D.; Dopico, A.M.; Parrill, A.L.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Targeting the hydrophobic pocket of autotaxin with virtual screening of inhibitors identifies a common aromatic sulfonamide structural motif

FEBS Journal
2014 | Journal article
EID:

2-s2.0-84894277134

Part of ISBN:

1742464X 17424658

Contributors: Fells, J.I.; Lee, S.C.; Norman, D.D.; Tsukahara, R.; Kirby, J.R.; Nelson, S.; Seibel, W.; Papoian, R.; Patil, R.; Miller, D.D. et al.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Autotaxin inhibition: Development and application of computational tools to identify site-selective lead compounds

Bioorganic and Medicinal Chemistry
2013 | Journal article
EID:

2-s2.0-84881367284

Part of ISBN:

09680896 14643391

Contributors: Norman, D.D.; Ibezim, A.; Scott, W.E.; White, S.; Parrill, A.L.; Baker, D.L.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Cerebrovascular dilation via selective targeting of the cholane steroid-recognition site in the bk channel β1-subunit by a novel nonsteroidal agents

Molecular Pharmacology
2013 | Journal article
EID:

2-s2.0-84876587544

Part of ISBN:

0026895X 15210111

Contributors: Bukiya, A.N.; McMillan, J.E.; Fedinec, A.L.; Patil, S.A.; Miller, D.D.; Leffler, C.W.; Parrill, A.L.; Dopico, A.M.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Computational design and experimental characterization of GPCR segment models

Methods in Enzymology
2013 | Book chapter
EID:

2-s2.0-84873357843

Part of ISBN:

15577988 00766879

Contributors: Parrill, A.L.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Gold nanorods carrying paclitaxel for photothermal-chemotherapy of cancer

Bioconjugate Chemistry
2013 | Journal article
EID:

2-s2.0-84875434744

Part of ISBN:

10431802 15204812

Contributors: Ren, F.; Bhana, S.; Norman, D.D.; Johnson, J.; Xu, L.; Baker, D.L.; Parrill, A.L.; Huang, X.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Hits of a high-throughput screen identify the hydrophobic pocket of autotaxin/lysophospholipase D as an inhibitory surface

Molecular Pharmacology
2013 | Journal article
EID:

2-s2.0-84883138075

Part of ISBN:

0026895X 15210111

Contributors: Fells, J.I.; Lee, S.C.; Fujiwara, Y.; Norman, D.D.; Lim, K.G.; Tsukahara, R.; Liu, J.; Patil, R.; Miller, D.D.; Kirby, R.J. et al.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Integrating the puzzle pieces: The current atomistic picture of phospholipid-G protein coupled receptor interactions

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
2013 | Journal article
EID:

2-s2.0-84868556353

Part of ISBN:

13881981 18792618

Contributors: Parrill, A.L.; Tigyi, G.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Polymer concepts illustrated in the context of biopolymers

ACS Symposium Series
2013 | Book
EID:

2-s2.0-84905369945

Part of ISBN:

19475918 00976156

Contributors: Baker, D.L.; Parrill, A.L.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Structural characterization of an LPA<inf>1</inf> second extracellular loop mimetic with a self-assembling coiled-coil folding constraint

International Journal of Molecular Sciences
2013 | Journal article
EID:

2-s2.0-84875103206

Part of ISBN:

16616596 14220067

Contributors: Young, J.K.; Clayton, B.T.; Kikonyogo, A.; Pham, T.-C.T.; Parrill, A.L.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Comparative modeling of lipid receptors

Methods in Molecular Biology
2012 | Book
EID:

2-s2.0-84934442769

Part of ISBN:

10643745

Contributors: Parrill, A.L.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Introductory molecular orbital theory: An honors general chemistry computational lab as implemented using three-dimensional modeling software

Journal of Chemical Education
2012 | Journal article
EID:

2-s2.0-84867476244

Part of ISBN:

00219584

Contributors: Ruddick, K.R.; Parrill, A.L.; Petersen, R.L.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

JCE classroom activity #113: An interlocking building block activity in writing formulas of ionic compounds

Journal of Chemical Education
2012 | Journal article
EID:

2-s2.0-84867475289

Part of ISBN:

00219584

Contributors: Ruddick, K.R.; Parrill, A.L.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Multiple cholesterol recognition/interaction amino acid consensus (CRAC) motifs in cytosolic C tail of Slo1 subunit determine cholesterol sensitivity of Ca<sup>2+</sup>- and voltage-gated K<sup>+</sup> (BK) channels

Journal of Biological Chemistry
2012 | Journal article
EID:

2-s2.0-84862001785

Part of ISBN:

00219258 1083351X

Contributors: Singh, A.K.; McMillan, J.; Bukiya, A.N.; Burton, B.; Parrill, A.L.; Dopico, A.M.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Structure of the first sphingosine 1-phosphate receptor

Science Signaling
2012 | Journal article
EID:

2-s2.0-84861463087

Part of ISBN:

19450877 19379145

Contributors: Parrill, A.L.; Lima, S.; Spiegel, S.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Virtual screening for LPA<inf>2</inf>-specific agonists identifies a nonlipid compound with antiapoptotic actions

Molecular Pharmacology
2012 | Journal article
EID:

2-s2.0-84869786660

Part of ISBN:

0026895X 15210111

Contributors: Kiss, G.N.; Fells, J.I.; Gupte, R.; Lee, S.-C.; Liu, J.; Nusser, N.; Lim, K.G.; Ray, R.M.; Lin, F.-T.; Parrill, A.L. et al.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Benzyl and naphthalene methylphosphonic acid inhibitors of autotaxin with anti-invasive and anti-metastatic activity

ChemMedChem
2011 | Journal article
EID:

2-s2.0-79954997189

Part of ISBN:

18607179 18607187

Contributors: Gupte, R.; Patil, R.; Liu, J.; Wang, Y.; Lee, S.C.; Fujiwara, Y.; Fells, J.; Bolen, A.L.; Emmons-Thompson, K.; Yates, C.R. et al.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Computational identification and experimental characterization of substrate binding determinants of nucleotide pyrophosphatase/phosphodiesterase 7

BMC Biochemistry
2011 | Journal article
EID:

2-s2.0-83455255111

Part of ISBN:

14712091

Contributors: Parrill, A.L.; Wanjala, I.W.; Pham, T.; Baker, D.L.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

FTY720 (gilenya) phosphate selectivity of sphingosine 1-phosphate receptor subtype 1 (S1P <inf>1</inf>) G protein-coupled receptor requires motifs in intracellular loop 1 and transmembrane domain

Journal of Biological Chemistry
2011 | Journal article
EID:

2-s2.0-80052246520

Part of ISBN:

00219258 1083351X

Contributors: Valentine, W.J.; Godwin, V.I.; Osborne, D.A.; Liu, J.; Fujiwara, Y.; Van Brocklyn, J.; Bittman, R.; Parrill, A.L.; Tigyi, G.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

GPCR conformations: Implications for rational drug design

Pharmaceuticals
2011 | Journal article
EID:

2-s2.0-79551610899

Part of ISBN:

14248247

Contributors: Parrill, A.L.; Bautista, D.L.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Ligand-based autotaxin pharmacophore models reflect structure-based docking results

Journal of Molecular Graphics and Modelling
2011 | Journal article
EID:

2-s2.0-80053922972

Part of ISBN:

10933263 18734243

Contributors: Mize, C.D.; Abbott, A.M.; Gacasan, S.B.; Parrill, A.L.; Baker, D.L.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Lysophosphatidic acid receptor agonists and antagonists (WO2010051053)

Expert Opinion on Therapeutic Patents
2011 | Journal article
EID:

2-s2.0-79952969747

Part of ISBN:

13543776

Contributors: Parrill, A.L.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

The steroid interaction site in transmembrane domain 2 of the large conductance, voltage- and calcium-gated potassium (BK) channel accessory β1 subunit

Proceedings of the National Academy of Sciences of the United States of America
2011 | Journal article
EID:

2-s2.0-84055200507

Part of ISBN:

00278424 10916490

Contributors: Bukiya, A.N.; Singh, A.K.; Parrill, A.L.; Dopico, A.M.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

(S)-FTY720-Vinylphosphonate, an analogue of the immunosuppressive agent FTY720, is a pan-antagonist of sphingosine 1-phosphate GPCR signaling and inhibits autotaxin activity

Cellular Signalling
2010 | Journal article
EID:

2-s2.0-77954514553

Part of ISBN:

08986568

Contributors: Valentine, W.J.; Kiss, G.N.; Liu, J.; E, S.; Gotoh, M.; Murakami-Murofushi, K.; Pham, T.C.; Baker, D.L.; Parrill, A.L.; Lu, X. et al.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

2D binary QSAR modeling of LPA<inf>3</inf> receptor antagonism

Journal of Molecular Graphics and Modelling
2010 | Journal article
EID:

2-s2.0-77951974258

Part of ISBN:

10933263

Contributors: Fells, J.I.; Tsukahara, R.; Liu, J.; Tigyi, G.; Parrill, A.L.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier

Autotaxin inhibitors: A perspective on initial medicinal chemistry efforts

Expert Opinion on Therapeutic Patents
2010 | Journal article
EID:

2-s2.0-78649239509

Part of ISBN:

13543776

Contributors: Parrill, A.L.; Baker, D.L.
Source: Self-asserted source
Abby Parrill via Scopus - Elsevier
Items per page:
Page 1 of 3

Peer review (7 reviews for 4 publications/grants)

Review activity for Engineering. (2)
Review activity for Journal of molecular graphics & modelling. (3)
Review activity for Journal of Pharmaceutical Analysis. (1)
Review activity for Nature communications (1)