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University of Natural Sciences and Humanities in Siedlce: Siedlce, PL

1983-11-03 to present (Institute of Chemistry)
Employment
Source: Self-asserted source
Zbigniew Karczmarzyk

Works (50 of 106)

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Page 1 of 3

Application of in silico methods to assess the anticancer potential of new derivatives of 4-fluorophenoxythiosemicarbazide derivatives

Journal of Molecular Structure
2025-04 | Journal article
Contributors: Paweł Kozyra; Waldemar Wysocki; Łucja Justyna Walczak; Mariola Herbet; Zbigniew Karczmarzyk; Monika Pitucha
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N-Substituted 2-(Benzenosulfonyl)-1-Carbotioamide Derivatives Exert Antimicrobial and Cytotoxic Effects via Aldehyde Dehydrogenase Pathway: Synthesis, In Silico and In Vitro Studies

Pharmaceuticals
2023-12-08 | Journal article
Contributors: Lucja Walczak-Nowicka; Anna Biernasiuk; Wojciech Ziemichód; Zbigniew Karczmarzyk; Mateusz Kwaśnik; Paweł Kozyra; Waldemar Wysocki; Agnieszka Stenzel-Bembenek; Dorota Kowalczuk; Mariola Herbet et al.
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Experimental and computational studies of tautomerism pyridine carbonyl thiosemicarbazide derivatives

Structural Chemistry
2023-10 | Journal article
Contributors: Paweł Kozyra; Agnieszka Kaczor; Zbigniew Karczmarzyk; Waldemar Wysocki; Monika Pitucha
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Synthesis, structure and sulfonamide–sulfonimide tautomerism of sulfonamide–1,2,4-triazine derivatives

Acta Crystallographica Section C Structural Chemistry
2022-09-01 | Journal article
Part of ISSN: 2053-2296
Contributors: Zbigniew Karczmarzyk; Danuta Branowska; Waldemar Wysocki; Ewa Wolinska; Karolina Koc; Katarzyna Stańska; Barbara Miroslaw; Zbigniew Karczmarzyk
Source: Self-asserted source
Zbigniew Karczmarzyk

Polymer microspheres modified with pyrazole derivatives as potential agents in anticancer therapy – Preliminary studies

Bioorganic Chemistry
2022-06 | Journal article
Part of ISSN: 0045-2068
Contributors: Zbigniew Karczmarzyk; Podkoscielna; Katarzyna Klimek; Zbigniew Karczmarzyk; Waldemar Wysocki; Małgorzata Brodacka; Karolina Serafin; Pawel Kozyra; Dorota Kowalczuk; Grazyna Ginalska et al.
Source: Self-asserted source
Zbigniew Karczmarzyk

Potential Anticancer Agents against Melanoma Cells Based on an As-Synthesized Thiosemicarbazide Derivative

Biomolecules
2022-01-18 | Journal article
Contributors: Paweł Kozyra; Agnieszka Korga-Plewko; Zbigniew Karczmarzyk; Anna Hawrył; Waldemar Wysocki; Michał Człapski; Magdalena Iwan; Marta Ostrowska-Leśko; Emilia Fornal; Monika Pitucha
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Influence of Complexation of Thiosemicarbazone Derivatives with Cu (II) Ions on Their Antitumor Activity against Melanoma Cells

International Journal of Molecular Sciences
2021-03-18 | Journal article
Contributors: Monika Pitucha; Agnieszka Korga-Plewko; Agnieszka Czylkowska; Bartłomiej Rogalewicz; Monika Drozd; Magdalena Iwan; Joanna Kubik; Ewelina Humeniuk; Grzegorz Adamczuk; Zbigniew Karczmarzyk et al.
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Chiral Pyrazolo[4,3-e][1,2,4]triazine Sulfonamides—Their Biological Activity, Lipophilicity, Protein Affinity, and Metabolic Transformations

Applied Sciences
2021-03-16 | Journal article
Contributors: Zofia Bernat; Anna Mieszkowska; Zofia Mazerska; Joanna Matysiak; Zbigniew Karczmarzyk; Katarzyna Kotwica-Mojzych; Mariusz Mojzych
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New Application of 1,2,4-Triazole Derivatives as Antitubercular Agents. Structure, In Vitro Screening and Docking Studies

Molecules
2020-12-19 | Journal article
Part of ISSN: 1420-3049
Source: Self-asserted source
Zbigniew Karczmarzyk

Synthesis and structural study of some N-acyl-4-allylsemicarbazides and the product of their cyclization with a potential antimicrobial activity

Journal of Molecular Structure
2020-11 | Journal article
Part of ISSN: 0022-2860
Source: Self-asserted source
Zbigniew Karczmarzyk

1,2,4-Triazine Sulfonamides: Synthesis by Sulfenamide Intermediates, In Vitro Anticancer Screening, Structural Characterization, and Molecular Docking Study

Molecules
2020-05-16 | Journal article
Part of ISSN: 1420-3049
Source: Self-asserted source
Zbigniew Karczmarzyk

Synthesis, Structural Characterization, and Biological Activity of New Pyrazolo[4,3-e][1,2,4]triazine Acyclonucleosides

Molecules
2020-01-05 | Journal article
Contributors: Mariusz Mojzych; Zofia Bernat; Zbigniew Karczmarzyk; Joanna Matysiak; Andrzej Fruziński
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Reinvestigation of the reaction of 3-substituted 1,2,4-triazines with nitronate anions: unexpected behavior of 3-(2-ethoxyphenyl)-1,2,4-triazine in the reaction with anions of nitroalkanes

Chemistry of Heterocyclic Compounds
2019-10 | Journal article
Part of ISSN: 0009-3122
Part of ISSN: 1573-8353
Source: Self-asserted source
Zbigniew Karczmarzyk

Synthesis, In Vitro Screening and Docking Studies of New Thiosemicarbazide Derivatives as Antitubercular Agents

Molecules
2019-01-11 | Journal article
Part of ISSN: 1420-3049
Source: Self-asserted source
Zbigniew Karczmarzyk

Design, synthesis, structure elucidation and in vitro antiviral and antimicrobial evaluation

Journal of the Iranian Chemical Society
2018 | Journal article
EID:

2-s2.0-85042408114

Contributors: Pachuta-Stec, A.; Rajtar, B.; Biernasiuk, A.; Karczmarzyk, Z.; Świątek, Ł.; Malm, A.; Wysocki, W.; Stepaniuk, K.; Polz-Dacewicz, M.; Pitucha, M.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

Synthesis of unsymmetrical disulfanes bearing 1,2,4-triazine scaffold and their in vitro screening towards anti-breast cancer activity

Monatshefte fur Chemie
2018 | Journal article
EID:

2-s2.0-85049098743

Contributors: Branowska, D.; Ławecka, J.; Sobiczewski, M.; Karczmarzyk, Z.; Wysocki, W.; Wolińska, E.; Olender, E.; Mirosław, B.; Perzyna, A.; Bielawska, A. et al.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

Synthesis, structure and antiproliferative activity of new pyrazolo[4,3- e]triazolo[4,5-b][1,2,4]triazine derivatives

Medicinal Chemistry
2018 | Journal article
EID:

2-s2.0-85041644827

Contributors: Mojzych, M.; Tarasiuk, P.; Karczmarzyk, Z.; Juszczak, M.; Rzeski, W.; Fruzilski, A.; Wolny, A.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

Crystal structure of 3,3′-di(furan-2-yl)-5,5′-bi-1,2,4-triazine

Zeitschrift fur Kristallographie - New Crystal Structures
2017 | Journal article
EID:

2-s2.0-85008701869

Contributors: Karczmarzyk, Z.; Branowska, D.; Wysocki, W.; Bancerz, I.; Urbańczyk-Lipkowska, Z.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

Novel thiosemicarbazide derivatives with 4-nitrophenyl group as multi-target drugs: α-glucosidase inhibitors with antibacterial and antiproliferative activity

Biomedicine and Pharmacotherapy
2017 | Journal article
EID:

2-s2.0-85025083173

Contributors: Wos, M.; Miazga-Karska, M.; Kaczor, A.A.; Klimek, K.; Karczmarzyk, Z.; Kowalczuk, D.; Wysocki, W.; Ginalska, G.; Urbanczyk-Lipkowska, Z.; Morawiak, M. et al.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

Synthesis and optical properties of some 3,4-(ethylenedioxythiophen-2-yl)-1,2,4-triazine derivatives

Tetrahedron
2017 | Journal article
EID:

2-s2.0-85007354635

Contributors: Branowska, D.; Olender, E.; Świętochowska, M.; Karczmarzyk, Z.; Wysocki, W.; Cichosz, I.; Woźna, A.; Urbańczyk-Lipkowska, Z.; Kalicki, P.; Gil, M.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

The crystal structure of methyl N-(4-bromophenyl)carbamate, C<inf>8</inf>H<inf>8</inf>BrNO<inf>2</inf>

Zeitschrift fur Kristallographie - New Crystal Structures
2017 | Journal article
EID:

2-s2.0-85033225302

Contributors: Karczmarzyk, Z.; Pitucha, M.; Wysocki, W.; Morawiak, M.; Sobótka-Polska, K.; Urbańczyk-Lipkowska, Z.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

Discovery of nitroaryl urea derivatives with antiproliferative properties

Journal of Enzyme Inhibition and Medicinal Chemistry
2016 | Journal article
EID:

2-s2.0-84964650719

Contributors: Wróbel, T.M.; Kiełbus, M.; Kaczor, A.A.; Kryštof, V.; Karczmarzyk, Z.; Wysocki, W.; Fruziński, A.; Król, S.K.; Grabarska, A.; Stepulak, A. et al.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

Structural characterization of copper complexes with chiral 1,2,4-triazine-oxazoline ligands

Heterocyclic Communications
2016 | Journal article
EID:

2-s2.0-84991056264

Contributors: Wolińska, E.; Karczmarzyk, Z.; Wysocki, W.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

Synthesis and electrochemical characterization of oligothiophenes with 1,2,4-triazine and 5,5′-bi-1,2,4-triazine as strong electron acceptor units

Electrochimica Acta
2016 | Journal article
EID:

2-s2.0-84981156471

Contributors: Branowska, D.; Olender, E.; Wysocki, W.; Karczmarzyk, Z.; Bancerz, I.; Ledwon, P.; Lapkowski, M.; Mirosław, B.; Urbańczyk-Lipkowska, Z.; Kalicki, P.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

The crystal structure of 4-allyl-5-benzyl-2,4-dihydro-3H-1,2,4-triazol-3-one, C<inf>12</inf>H<inf>13</inf>N<inf>3</inf>O

Zeitschrift fur Kristallographie - New Crystal Structures
2016 | Journal article
EID:

2-s2.0-84960863513

Contributors: Karczmarzyk, Z.; Pitucha, M.; Wos̈, M.; Wysocki, W.; Urbańczyk-Lipkowska, Z.; Morawiak, M.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

New approaches to the synthesis of sildenafil analogues and their enzyme inhibitory activity

Bioorganic and Medicinal Chemistry
2015 | Journal article
EID:

2-s2.0-84925491553

Contributors: Mojzych, M.; Karczmarzyk, Z.; Wysocki, W.; Ceruso, M.; Supuran, C.T.; Kryštof, V.; Urbańczyk-Lipkowska, Z.; Kalicki, P.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

Structural investigations of a series of 1,6-aryl-7-hydroxy-2,3-dihydroimidazo[1,2-a]pyrimidin-5(1H)-ones with potential antinociceptive activity

Journal of Molecular Structure
2015 | Journal article
EID:

2-s2.0-84928311239

Contributors: Wysocki, W.; Karczmarzyk, Z.; Rządkowska, M.; Szacoń, E.; Matosiuk, D.; Urbańczyk-Lipkowska, Z.; Kalicki, P.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

Synthesis, photophysics and electrochemical properties of 1,1′-(2,2′-bithiophene-5,5′-diyl)bis(cycloalkeno[c]pyridine) as a result of the Diels-Alder reaction of 3-(2-thienyl)-1,2,4-triazine

New Journal of Chemistry
2015 | Journal article
EID:

2-s2.0-84947929252

Contributors: Branowska, D.; Wysocki, W.; Olender, E.; Ławecka, J.; Chaciak, B.; Ledwon, P.; Lapkowski, M.; Karczmarzyk, Z.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

Synthesis, structural studies and molecular modelling of a novel imidazoline derivative with antifungal activity

Molecules
2015 | Journal article
EID:

2-s2.0-84941248215

Contributors: Wróbel, T.M.; Kosikowska, U.; Kaczor, A.A.; Andrzejczuk, S.; Karczmarzyk, Z.; Wysocki, W.; Urbanczyk-Lipkowska, Z.; Morawiak, M.; Matosiuk, D.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

Synthetic approaches for sulfur derivatives containing 1,2,4-triazine moiety: Their activity for in vitro screening towards two human cancer cell lines

Chemical and Pharmaceutical Bulletin
2015 | Journal article
EID:

2-s2.0-84940367392

Contributors: Karczmarzyk, Z.; Wysocki, W.; Urbańczyk-Lipkowska, Z.; Kalicki, P.; Bielawska, A.; Bielawski, K.; Ławecka, J.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

A convenient synthesis of 5,5′-bi-1,2,4-triazines via direct S-arylation and its application in the synthesis of 2,2′-bipyridines

Heterocyclic Communications
2014 | Journal article
EID:

2-s2.0-84896758545

Contributors: Ławecka, J.; Olender, E.; Karczmarzyk, Z.; Wysocki, W.; Branowska, D.; Urbańczyk-Lipkowska, Z.; Kalicki, P.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

Structural Studies on N-(1-naphthyl)-3-amino-5-oxo-4-phenyl-1Hpyrazole-1- carboxamide with antibacterial activity

Letters in Organic Chemistry
2014 | Journal article
EID:

2-s2.0-84893326387

Contributors: Kaczor, A.A.; Wróbel, T.; Karczmarzyk, Z.; Wysocki, W.; Fruzinski, A.; Brodacka, M.; Matosiuk, D.; Pitucha, M.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

Structural studies, homology modeling and molecular docking of novel non-competitive antagonists of GluK1/GluK2 receptors

Bioorganic and Medicinal Chemistry
2014 | Journal article
EID:

2-s2.0-84892368749

Contributors: Kaczor, A.A.; Karczmarzyk, Z.; Fruziński, A.; Pihlaja, K.; Sinkkonen, J.; Wiinämaki, K.; Kronbach, C.; Unverferth, K.; Poso, A.; Matosiuk, D.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

Valence tautomerism of new pyrazolo[4,3-e]tetrazole[4,5-b][1,2,4]triazines

Journal of Molecular Structure
2014 | Journal article
EID:

2-s2.0-84898472010

Contributors: Mojzych, M.; Karczmarzyk, Z.; Wysocki, W.; Urbańczyk-Lipkowska, Z.; Zaczek, N.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

3-Benzyl-4-ethyl-1H-1,2,4-triazole-5(4H)-thione

Acta Crystallographica Section E: Structure Reports Online
2013 | Journal article
EID:

2-s2.0-84873378271

Contributors: Karczmarzyk, Z.; Pitucha, M.; Wysocki, W.; Pachuta-Stec, A.; Stańczuk, A.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

Erratum: Synthesis, photophysics and electrochemistry of novel, nitrogen-containing heterocyclic derivatives (New Journal of Chemistry (2013) 37 (1982-1988) DOI:10.1039/C3NJ00078H)

New Journal of Chemistry
2013 | Journal article
EID:

2-s2.0-84887853686

Contributors: Branowska, D.; Chaciak, B.; Siuchta, O.; Olender, E.; Ledwon, P.; Lapkowski, M.; Poronik, E.; Wysocki, W.; Karczmarzyk, Z.; Skorka, L. et al.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

Experimental and computational studies on the tautomerism of N-substituted 3-amino-5-oxo-4-phenyl-1H-pyrazolo-1-carboxamides with antibacterial activity

Journal of Molecular Structure
2013 | Journal article
EID:

2-s2.0-84884739538

Contributors: Kaczor, A.A.; Wróbel, T.; Karczmarzyk, Z.; Wysocki, W.; Mendyk, E.; Poso, A.; Matosiuk, D.; Pitucha, M.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

Structural and molecular docking studies of 4-benzyl-3-[(1-methylpyrrol- 2-yl)methyl]-4,5-dihydro-1h-1,2,4-triazol-5-one with anticancer activity

Medicinal Chemistry
2013 | Journal article
EID:

2-s2.0-84877945166

Contributors: Kaczor, A.A.; Pitucha, M.; Karczmarzyk, Z.; Wysocki, W.; Rzymowska, J.; Matosiuk, D.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

Synthesis and characterization of osmium(II) chlorocarbonyl complexes with bidentate phosphines

Inorganic Chemistry Communications
2013 | Journal article
EID:

2-s2.0-84869876939

Contributors: Kamecka, A.; Kapturkiewicz, A.; Karczmarzyk, Z.; Wysocki, W.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

Synthesis of novel isothiazolopyridines and their in vitro evaluation against Mycobacterium and Propionibacterium acnes

Bioorganic and Medicinal Chemistry
2013 | Journal article
EID:

2-s2.0-84881370658

Contributors: Malinka, W.; Świa̧tek, P.; Śliwińska, M.; Szponar, B.; Gamian, A.; Karczmarzyk, Z.; Fruziński, A.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

Synthesis, photophysics and electrochemistry of novel, nitrogen-containing heterocyclic derivatives

New Journal of Chemistry
2013 | Journal article
EID:

2-s2.0-84883055280

Contributors: Branowska, D.; Chaciak, B.; Siuchta, O.; Olender, E.; Ledwon, P.; Lapkowski, M.; Poronik, E.; Wysocki, W.; Karczmarzyk, Z.; Skora, L. et al.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

The pseudo-Michael reaction of 1-aryl-4,5-dihydro-1H-imidazol-2-amines with ethyl ethoxymethylenecyanoacetate

Monatshefte fur Chemie
2013 | Journal article
EID:

2-s2.0-84880766781

Contributors: Kaczor, A.A.; Kijkowska-Murak, U.; Pihlaja, K.; Sinkkonen, J.; Wysocki, W.; Karczmarzyk, Z.; Matosiuk, D.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

2-(3-Chloro-5,6-diphenyl-2,5-dihydro-1,2,4-triazin-5-yl) -2-methylpropanenitrile

Acta Crystallographica Section E: Structure Reports Online
2012 | Journal article
EID:

2-s2.0-84872752085

Contributors: Wolińska, E.; Karczmarzyk, Z.; Rykowski, A.; Urbańczyk-Lipkowska, Z.; Kalicki, P.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

2-(5,6-Diphenyl-1,2,4-triazin-3-yl)aniline

Acta Crystallographica Section E: Structure Reports Online
2012 | Journal article
EID:

2-s2.0-84870945539

Contributors: Mojzych, M.; Karczmarzyk, Z.; Fruziński, A.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

Ethyl 2-(3-methyl-5-sulfanylidene-4,5-dihydro-1H-1,2,4-triazol-4-yl)acetate

Acta Crystallographica Section E: Structure Reports Online
2012 | Journal article
EID:

2-s2.0-84870871566

Contributors: Karczmarzyk, Z.; Pitucha, M.; Wysocki, W.; Fruziński, A.; Olender, E.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

5,5′,6,6′-Tetra-methyl-3,3′-bi-1,2,4-tri-azine

Acta Crystallographica Section E: Structure Reports Online
2011 | Journal article
EID:

2-s2.0-84855292987

Contributors: Wolińska, E.; Karczmarzyk, Z.; Rykowski, A.; Wysocki, W.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

5,6,7,8-Tetra-hydro-quinolin-8-one

Acta Crystallographica Section E: Structure Reports Online
2011 | Journal article
EID:

2-s2.0-79957973613

Contributors: Lipińska, T.M.; Karczmarzyk, Z.; Wysocki, W.; Gruba, E.; Fruziski, A.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

A facile approach to 2,2′-bipyridine based thiacrown ethers and their sulfoxides by DA-rDA reaction of 5,5′-bi-1,2,4-triazine thiamacrocycles. The conformation studies

Arkivoc
2011 | Journal article
EID:

2-s2.0-79955037820

Contributors: Ławecka, J.; Karczmarzyk, Z.; Olender, E.; Wolińska, E.; Branowska, D.; Rykowski, A.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

A novel approach to conformationally strained 2,2′-bipyridine thiacrown ethers and their chiral sulfoxides by sequential homo-coupling/DA-rDA reaction of 5,5′-bi-1,2,4-triazine-containing thiamacrocycles

Tetrahedron
2011 | Journal article
EID:

2-s2.0-79953698126

Contributors: Ławecka, J.; Karczmarzyk, Z.; Wolińska, E.; Olender, E.; Branowska, D.; Rykowski, A.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier

An unusual transformation of 5-acyl-1,2,4-triazines into 3-pyridyl-1,2,4-triazines via tandem Stille cross-coupling/aza Diels-Alder reaction

Tetrahedron Letters
2011 | Journal article
EID:

2-s2.0-82255175433

Contributors: Branowska, D.; Siuchta, O.; Karczmarzyk, Z.; Wysocki, W.; Wolińska, E.; Mojzych, M.; Kawecki, R.
Source: Self-asserted source
Zbigniew Karczmarzyk via Scopus - Elsevier
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Peer review (13 reviews for 2 publications/grants)

Review activity for Informatics in medicine unlocked. (1)
Review activity for Journal of molecular structure. (12)