Personal information

Emails & domains

Verified email addresses

Verified email domains

Websites & social links

Vlaming lab
Twitter
LinkedIn
Adelman lab
Van Leeuwen lab

Other IDs

Loop profile: 2074132

Activities

Collapse all

Employment (3)

Universiteit Utrecht: Utrecht, NL

Employment
Source: check_circle
Utrecht University

Harvard Medical School: Boston, MA, US

2017-04-01 to 2022-12-31 | Postdoctoral Fellow (BCMP)
Employment
Source: Self-asserted source
Hanneke Vlaming

Netherlands Cancer Institute: Amsterdam, NL

2010-11-01 to 2016-11-30 | PhD student (Gene Regulation)
Employment
Source: Self-asserted source
Hanneke Vlaming

Works (17)

Restrictor slows early transcription elongation to render RNA polymerase II susceptible to termination at non-coding RNA loci

2025-01-10 | Preprint
DOI: 10.1101/2025.01.08.631787
Contributors: Claudia A. Mimoso; Hanneke Vlaming; Nathalie P. de Wagenaar; Karen Adelman
Source: check_circle
Crossref

DOT1L inhibition does not modify the sensitivity of cutaneous T cell lymphoma to pan-HDAC inhibitors in vitro

Frontiers in Genetics
2022-11-08 | Journal article
DOI: 10.3389/fgene.2022.1032958
Part of ISSN: 1664-8021
Contributors: Eliza Mari Kwesi-Maliepaard; Muddassir Malik; Tibor van Welsem; Remco van Doorn; Maarten H. Vermeer; Hanneke Vlaming; Heinz Jacobs; Fred van Leeuwen
Source: Self-asserted source
Hanneke Vlaming

Screening thousands of transcribed coding and non-coding regions reveals sequence determinants of RNA polymerase II elongation potential

Nature Structural & Molecular Biology
2022-06 | Journal article
DOI: 10.1038/s41594-022-00785-9
Contributors: Hanneke Vlaming; Claudia A. Mimoso; Andrew R. Field; Benjamin J. E. Martin; Karen Adelman
Source: check_circle
Crossref

Epigenetics Identifier screens reveal regulators of chromatin acylation and limited specificity of acylation antibodies

Scientific Reports
2021-06 | Journal article
DOI: 10.1038/s41598-021-91359-0
Part of ISSN: 2045-2322
Source: Self-asserted source
Hanneke Vlaming

Screening thousands of transcribed coding and non-coding regions reveals sequence determinants of RNA polymerase II elongation potential

2021-06-01 | Other
DOI: 10.1101/2021.06.01.446655
Contributors: Hanneke Vlaming; Claudia A. Mimoso; Benjamin JE Martin; Andrew R Field; Karen Adelman
Source: check_circle
Crossref

Strength is in engagement

EMBO reports
2021-05-05 | Journal article
DOI: 10.15252/embr.202152612
Contributors: Christine E Cucinotta; Benjamin J E Martin; Melvin Noé González; Pravrutha Raman; Vladimir B Teif; Hanneke Vlaming
Source: check_circle
Crossref

The histone methyltransferase DOT1L prevents antigen-independent differentiation and safeguards epigenetic identity of CD8 + T cells

Proceedings of the National Academy of Sciences
2020-08-25 | Journal article
DOI: 10.1073/pnas.1920372117
Contributors: Eliza Mari Kwesi-Maliepaard; Muhammad Assad Aslam; Mir Farshid Alemdehy; Teun van den Brand; Chelsea McLean; Hanneke Vlaming; Tibor van Welsem; Tessy Korthout; Cesare Lancini; Sjoerd Hendriks et al.
Source: check_circle
Crossref

Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L‐dose dependency in HDAC1‐deficient thymic lymphoma

The EMBO Journal
2019-07-15 | Journal article
DOI: 10.15252/embj.2019101564
Contributors: Hanneke Vlaming; Chelsea M McLean; Tessy Korthout; Mir Farshid Alemdehy; Sjoerd Hendriks; Cesare Lancini; Sander Palit; Sjoerd Klarenbeek; Eliza Mari Kwesi‐Maliepaard; Thom M Molenaar et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Dot1 promotes H2B ubiquitination by a methyltransferase-independent mechanism

Nucleic Acids Research
2018-09-08 | Journal article
DOI: 10.1093/nar/gky801
Source: Self-asserted source
Hanneke Vlaming

Modeling Distributive Histone Modification by Dot1 Methyltransferases: From Mechanism to Biological Insights

Epigenetics and Systems Biology
2017 | Book chapter
DOI: 10.1016/B978-0-12-803075-2.00006-4
Source: Self-asserted source
Hanneke Vlaming

Direct screening for chromatin status on DNA barcodes in yeast delineates the regulome of H3K79 methylation by Dot1

eLife
2016-12-06 | Journal article
DOI: 10.7554/eLife.18919
Contributors: Hanneke Vlaming; Thom M Molenaar; Tibor van Welsem; Deepani W Poramba-Liyanage; Desiree E Smith; Arno Velds; Liesbeth Hoekman; Tessy Korthout; Sjoerd Hendriks; AF Maarten Altelaar et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

The upstreams and downstreams of H3K79 methylation by DOT1L.

2016-01 | Journal article
PMID: 26728620
Contributors: Vlaming H; van Leeuwen F
Source: Self-asserted source
Hanneke Vlaming via Europe PubMed Central

Dot1 histone methyltransferases share a distributive mechanism but have highly diverged catalytic properties.

2015 | Journal article
DOI: 10.1038/srep09824
PMID: 25965993
PMC: PMC4650758
Contributors: Stulemeijer IJ; De Vos D; van Harten K; Joshi OK; Blomberg O; van Welsem T; Terweij M; Vlaming H; de Graaf EL; Altelaar AF et al.
Source: Self-asserted source
Hanneke Vlaming via Europe PubMed Central
grade
Preferred source (of 2)‎

HDAC1 and HDAC2 collectively regulate intestinal stem cell homeostasis.

2015-05 | Journal article
DOI: 10.1096/fj.14-257931
PMID: 25648995
Contributors: Zimberlin CD; Lancini C; Sno R; Rosekrans SL; McLean CM; Vlaming H; van den Brink GR; Bots M; Medema JP; Dannenberg JH
Source: Self-asserted source
Hanneke Vlaming via Europe PubMed Central

Yeast PP4 interacts with ATR homolog Ddc2-Mec1 and regulates checkpoint signaling.

2015-01 | Journal article
DOI: 10.1016/j.molcel.2014.11.016
PMID: 25533186
Contributors: Hustedt N; Seeber A; Sack R; Tsai-Pflugfelder M; Bhullar B; Vlaming H; van Leeuwen F; Guénolé A; van Attikum H; Srivas R et al.
Source: Self-asserted source
Hanneke Vlaming via Europe PubMed Central

Flexibility in crosstalk between H2B ubiquitination and H3 methylation in vivo

EMBO Reports
2014 | Journal article | Author
DOI: 10.15252/embr.201438793
SOURCE-WORK-ID:

2bdc09c7-0a5d-43e9-9ffd-f0276d53328c

PMID: 25141862
EID:

2-s2.0-84908116435
Contributors: Hanneke Vlaming; Tibor van Welsem; Erik L de Graaf; David Ontoso; Maarten Altelaar; Pedro A San-Segundo; Albert Heck; Fred van Leeuwen
Source: check_circle
Utrecht University

Crosstalk between aging and the epigenome.

2012-02 | Journal article
DOI: 10.2217/epi.11.113
PMID: 22332652
Contributors: Vlaming H; van Leeuwen F
Source: Self-asserted source
Hanneke Vlaming via Europe PubMed Central

Peer review (3 reviews for 3 publications/grants)

Review activity for Journal of Molecular Biology. (1)
Review activity for Molecular cell. (1)
Review activity for Nature structural & molecular biology. (1)
How many people are using ORCID?