Personal information

natural products, biosynthesis, synthetic biology, metabolic engineering
China

Activities

Employment (3)

Shanghai Jiao Tong University: Shanghai, CN

2020-01-01 to present | Professor (Shanghai Center for Systems Biomedicine)
Employment
Source: Self-asserted source
Min-Juan Xu

Peking University: Beijing, Beijing, CN

2008-05-05 to 2010-02-31 | Assistant Professor
Employment
Source: Self-asserted source
Min-Juan Xu

Julius-Maximilians-Universität Würzburg: Wurzburg, Bayern, DE

2006-09-01 to 2008-03-31 | Post. Dr.
Employment
Source: Self-asserted source
Min-Juan Xu

Education and qualifications (2)

Peking University: Beijing, Beijing, CN

2001-09-01 to 2006-07-01 | Ph. D. (School of Pharmaceutical Sciences)
Education
Source: Self-asserted source
Min-Juan Xu

Peking University: Beijing, Beijing, CN

1997-09-01 to 2001-07-01 | Bachelor (School of Pharmaceutical Sciences)
Education
Source: Self-asserted source
Min-Juan Xu

Funding (2)

Identification and characterization of the biosynthesis pathway and bioactive study for benzo[f][1,7]naphthyridine in Streptomyces albogriseolus

Grant
National Natural Science Foundation of China (Beijing, CN)
GRANT_NUMBER:

81273404

Source: Self-asserted source
Min-Juan Xu

Study on structural diversity leading compound, xiamenmycin and bioactive mechanism of anti-hepatic fibrosis

Grant
National Natural Science Foundation of China (Beijing, CN)
GRANT_NUMBER:

81473105

Source: Self-asserted source
Min-Juan Xu

Works (18)

Computational Exploration of How Enzyme XimE Converts Natural S-Epoxide to Pyran and R-Epoxide to Furan

ACS Catalysis
2021-07-02 | Journal article
Part of ISSN: 2155-5435
Part of ISSN: 2155-5435
Contributors: Min-Juan Xu
Source: Self-asserted source
Min-Juan Xu

Identification of an α-Oxoamine Synthase and a One-Pot Two-Step Enzymatic Synthesis of α-Amino Ketones

Organic Letters
2021-01-01 | Journal article
Part of ISSN: 1523-7060
Part of ISSN: 1523-7052
Contributors: Min-Juan Xu
Source: Self-asserted source
Min-Juan Xu

Constructing Microbial Hosts for the Production of Benzoheterocyclic Derivatives

ACS Synthetic Biology
2020-09-18 | Journal article
Part of ISSN: 2161-5063
Part of ISSN: 2161-5063
Contributors: Min-Juan Xu
Source: Self-asserted source
Min-Juan Xu

Ikarugamycin inhibits pancreatic cancer cell glycolysis by targeting hexokinase 2

The FASEB Journal
2020-03 | Journal article
Part of ISSN: 0892-6638
Part of ISSN: 1530-6860
Contributors: Min-Juan Xu
Source: Self-asserted source
Min-Juan Xu

Three transcriptional regulators positively regulate the biosynthesis of polycyclic tetramate macrolactams in Streptomyces xiamenensis 318

Applied Microbiology and Biotechnology
2020-01 | Journal article
Part of ISSN: 0175-7598
Part of ISSN: 1432-0614
Contributors: Min-Juan Xu
Source: Self-asserted source
Min-Juan Xu

Rational engineering of amide synthetase enables bioconversion to diverse xiamenmycin derivatives

Chemical Communications
2019 | Journal article
Part of ISSN: 1359-7345
Part of ISSN: 1364-548X
Contributors: Min-Juan Xu
Source: Self-asserted source
Min-Juan Xu

Characterization and Nonenzymatic Transformation of Three Types of Alkaloids from <i>Streptomyces albogriseolus</i> MGR072 and Discovery of Inhibitors of Indoleamine 2,3-Dioxygenase

Organic Letters
2019-11-01 | Journal article
Part of ISSN: 1523-7060
Part of ISSN: 1523-7052
Contributors: Min-Juan Xu
Source: Self-asserted source
Min-Juan Xu

Enzymatic Pyran Formation Involved in Xiamenmycin Biosynthesis

ACS Catalysis
2019-06-07 | Journal article
Part of ISSN: 2155-5435
Part of ISSN: 2155-5435
Contributors: Min-Juan Xu
Source: Self-asserted source
Min-Juan Xu

A Novel AdpA Homologue Negatively Regulates Morphological Differentiation in Streptomyces xiamenensis 318

Applied and Environmental Microbiology
2019-04 | Journal article
Part of ISSN: 0099-2240
Part of ISSN: 1098-5336
Contributors: Min-Juan Xu
Source: Self-asserted source
Min-Juan Xu

Structural diversity of anti-pancreatic cancer capsimycins identified in mangrove-derived Streptomyces xiamenensis 318 and post-modification via a novel cytochrome P450 monooxygenase.

Sci. Rep.
2017 | Journal article
Source: Self-asserted source
Min-Juan Xu

Deciphering the streamlined genome of Streptomyces xiamenensis 318 as the producer of the anti-fibrotic drug candidate xiamenmycin

Sci. Rep.
2016 | Journal article
Source: Self-asserted source
Min-Juan Xu

Total synthesis and stereochemical revision of xiamenmycin A.

Org. Biomol. Chem.
2016 | Journal article
Source: Self-asserted source
Min-Juan Xu

Harnessing the Potential of Halogenated Natural Product Biosynthesis by Mangrove-Derived Actinomycetes

Marine Drugs
2013-10-14 | Journal article
Part of ISSN: 1660-3397
Contributors: Min-Juan Xu
Source: Self-asserted source
Min-Juan Xu

Xiamenmycin Attenuates Hypertrophic Scars by Suppressing Local Inflammation and the Effects of Mechanical Stress

Journal of Investigative Dermatology
2013-05 | Journal article
Part of ISSN: 0022-202X
Contributors: Min-Juan Xu
Source: Self-asserted source
Min-Juan Xu

First total synthesis and determination of the absolute configuration of 1-N-methyl-3-methylamino-[N-butanoicacid-3-(9-methyl-8-propen-7-one)-amide]-benzo[f][1,7]naphthyridine-2-one, a novel benzonaphthyridine alkaloid

Tetrahedron Letters
2012-09 | Journal article
Part of ISSN: 0040-4039
Contributors: Min-Juan Xu
Source: Self-asserted source
Min-Juan Xu

Identification and Characterization of an Anti-Fibrotic Benzopyran Compound Isolated from Mangrove-Derived Streptomyces xiamenensis

Marine Drugs
2012-03-15 | Journal article
Part of ISSN: 1660-3397
Contributors: Min-Juan Xu
Source: Self-asserted source
Min-Juan Xu

A Novel Benzo[f][1,7]Naphthyridine Produced by Streptomyces Albogriseolus from Mangrove Sediments

Molecules
2010-12-15 | Journal article
Part of ISSN: 1420-3049
Contributors: Min-Juan Xu
Source: Self-asserted source
Min-Juan Xu

p-Aminoacetophenonic Acids Produced by a Mangrove Endophyte Streptomyces sp. (strain HK10552)

Molecules
2010-04-16 | Journal article
Part of ISSN: 1420-3049
Contributors: Min-Juan Xu
Source: Self-asserted source
Min-Juan Xu

Peer review (3 reviews for 2 publications/grants)

Review activity for Biochemistry. (1)
Review activity for Journal of natural products. (2)