Personal information

Other IDs

Scopus Author ID: 23034841400

Activities

Collapse all

Employment (3)

Massachusetts Institute of Technology: Cambridge, MA, US

2014-04-01 to present | Research scientist (Koch Institute for integrative cancer research)
Employment
Source: Self-asserted source
Guangan Hu

Massachusetts Institute of Technology: Cambridge, MA, US

2009-04-14 to 2014-03-31 | Postdoc associate (Koch Institute for integrative cancer research)
Employment
Source: Self-asserted source
Guangan Hu

Nanyang Technological University: Singapore, SG

2008-07-19 to 2009-03-31 | Research associate (School of biological sciences)
Employment
Source: Self-asserted source
Guangan Hu

Education and qualifications (3)

Nanyang Technological University: Singapore, SG

2004-07-19 to 2008-07-18 | PhD (School of biological sciences)
Education
Source: Self-asserted source
Guangan Hu

Hubei University: Wuhan, CN

2000-09-01 to 2003-06-30 | Master Science (School of life sciences)
Education
Source: Self-asserted source
Guangan Hu

Hubei University: Wuhan, CN

1996-09-01 to 2000-06-31 | BS (School of liefe sciences)
Education
Source: Self-asserted source
Guangan Hu

Works (22)

Activation of GPR3-β-arrestin2-PKM2 pathway in Kupffer cells stimulates glycolysis and inhibits obesity and liver pathogenesis

Nature Communications
2024-01-27 | Journal article
DOI: 10.1038/s41467-024-45167-5
Contributors: Ting Dong; Guangan Hu; Zhongqi Fan; Huirui Wang; Yinghui Gao; Sisi Wang; Hao Xu; Michael B. Yaffe; Matthew G. Vander Heiden; Guoyue Lv et al.
Source: check_circle
Crossref

Bosutinib stimulates macrophage survival, phagocytosis and intracellular killing of bacteria

2023-12-14 | Preprint
DOI: 10.1101/2023.12.13.571434
Contributors: Ronni A. G. da Silva; Claudia J. Stocks; Guangan Hu; Kimberly A. Kline; Jianzhu Chen
Source: check_circle
Crossref

Mitoxantrone targets both host and bacteria to overcome vancomycin resistance in Enterococcus faecalis

Science Advances
2023-02-24 | Journal article
DOI: 10.1126/sciadv.add9280
Contributors: Ronni A. G. da Silva; Jun Jie Wong; Haris Antypas; Pei Yi Choo; Karlyn Goh; Shreya Jolly; Cui Liang; Leona Tay Kwan Sing; Mark Veleba; Guangan Hu et al.
Source: check_circle
Crossref

Ovarian Cancer Ascites Inhibits Transcriptional Activation of NK Cells Partly through CA125

The Journal of Immunology
2022-05-01 | Journal article
DOI: 10.4049/jimmunol.2001095
Contributors: Christopher C Fraser; Bin Jia; Guangan Hu; Lojain Ibrahim Al Johani; Roberta Fritz-Klaus; James Dongjoo Ham; Raina N Fichorova; Kevin M Elias; Daniel William Cramer; Manish S Patankar et al.
Source: check_circle
Crossref

High-throughput phenotypic screen and transcriptional analysis identify new compounds and targets for macrophage reprogramming

Nature Communications
2021-02-03 | Journal article
DOI: 10.1038/s41467-021-21066-x
Contributors: Guangan Hu; Yang Su; Byong Ha Kang; Zhongqi Fan; Ting Dong; Douglas R. Brown; Jaime Cheah; Karl Dane Wittrup; Jianzhu Chen
Source: check_circle
Crossref

MFSD7C switches mitochondrial ATP synthesis to thermogenesis in response to heme

Nature Communications
2020-09-24 | Journal article
DOI: 10.1038/s41467-020-18607-1
Contributors: Yingzhong Li; Nikola A. Ivica; Ting Dong; Dimitrios P. Papageorgiou; Yanpu He; Douglas R. Brown; Marianna Kleyman; Guangan Hu; Walter W. Chen; Lucas B. Sullivan et al.
Source: check_circle
Crossref

LILRB3 (ILT5) is a myeloid checkpoint on myeloid cells that elicits profound immununomodulation

2020-06-06 | Preprint
DOI: 10.1101/2020.06.04.135400
Contributors: Muchaala Yeboah; Charys Papagregoriou; Des C. Jones; H.T. Claude Chan; Guangan Hu; Justine S. McPartlan; Torbjörn Schiött; Ulrika Mattson; C. Ian Mockridge; Ulla-Carin Tornberg et al.
Source: check_circle
Crossref

Vitamin D3-vitamin D receptor axis suppresses pulmonary emphysema by maintaining alveolar macrophage homeostasis and function

EBioMedicine
2019-07 | Journal article
DOI: 10.1016/j.ebiom.2019.06.039
Contributors: Guangan Hu; Ting Dong; Sisi Wang; Hongyu Jing; Jianzhu Chen
Source: check_circle
Crossref

Induction and Therapeutic Targeting of Human NPM1c+ Myeloid Leukemia in the Presence of Autologous Immune System in Mice

The Journal of Immunology
2019-03-15 | Journal article
DOI: 10.4049/jimmunol.1800366
Contributors: Mandeep Kaur; Adam C Drake; Guangan Hu; Stephen Rudnick; Qingfeng Chen; Ryan Phennicie; Ricardo Attar; Jeffrey Nemeth; Francois Gaudet; Jianzhu Chen
Source: check_circle
Crossref

Antibiotics induce polarization of pleural macrophages to M2-like phenotype in patients with tuberculous pleuritis.

Scientific reports
2017-11 | Journal article
DOI: 10.1038/s41598-017-14808-9
PMID: 29101376
PMC: PMC5670217
Contributors: Wang S; Zhang J; Sui L; Xu H; Piao Q; Liu Y; Qu X; Sun Y; Song L; Li D et al.
Source: Self-asserted source
Guangan Hu via Europe PubMed Central
grade
Preferred source (of 2)‎

Differentiation of Club Cells to Alveolar Epithelial Cells In Vitro.

Scientific reports
2017-01 | Journal article
DOI: 10.1038/srep41661
PMID: 28128362
PMC: PMC5269679
Contributors: Zheng D; Soh BS; Yin L; Hu G; Chen Q; Choi H; Han J; Chow VT; Chen J
Source: Self-asserted source
Guangan Hu via Europe PubMed Central

Information-dense analysis for information-dense understanding

Translational Cancer Research
2016-11 | Journal article
DOI: 10.21037/tcr.2016.11.21
Part of ISSN: 2218-676X
Contributors: Nikola A. Ivica; Mandeep Kaur; Guangan Hu; Jianzhu Chen
Source: Self-asserted source
Guangan Hu via Crossref Metadata Search

Integrated analysis of the Plasmodium species transcriptome.

EBioMedicine
2016-05 | Journal article
DOI: 10.1016/j.ebiom.2016.04.011
PMID: 27322479
PMC: PMC4909483
Contributors: Hoo R; Zhu L; Amaladoss A; Mok S; Natalang O; Lapp SA; Hu G; Liew K; Galinski MR; Bozdech Z et al.
Source: Self-asserted source
Guangan Hu via Europe PubMed Central

The Dawn of Systems Cancer Immunotherapy

Archives of Surgical Oncology
2015 | Journal article
DOI: 10.4172/2471-2671.1000e101
Part of ISSN: 2471-2671
Contributors: Guangan Hu
Source: Self-asserted source
Guangan Hu via Crossref Metadata Search

A genome-wide regulatory network identifies key transcription factors for memory CD8 + T-cell development

2013 | Journal article
DOI:

10.1038/ncomms3830

EID:

2-s2.0-84890638806
Contributors: Hu, G.; Chen, J.
Source: Self-asserted source
Guangan Hu via Scopus - Elsevier

Defining species specific genome differences in malaria parasites

2010 | Journal article
DOI:

10.1186/1471-2164-11-128

EID:

2-s2.0-77649290642
Contributors: Liew, K.J.L.; Hu, G.; Bozdech, Z.; Peter, P.R.
Source: Self-asserted source
Guangan Hu via Scopus - Elsevier

Transcriptional profiling of growth perturbations of the human malaria parasite Plasmodium falciparum

2010 | Journal article
DOI:

10.1038/nbt.1597

EID:

2-s2.0-74049111230
Contributors: Hu, G.; Cabrera, A.; Kono, M.; Mok, S.; Chaal, B.K.; Haase, S.; Engelberg, K.; Cheemadan, S.; Spielmann, T.; Preiser, P.R. et al.
Source: Self-asserted source
Guangan Hu via Scopus - Elsevier

Crystal structure of the FK506 binding domain of Plasmodium falciparum FKBP35 in complex with FK506

2008 | Journal article
DOI:

10.1021/bi800004u

EID:

2-s2.0-44449107714
Contributors: Kotaka, M.; Ye, H.; Alag, R.; Hu, G.; Bozdech, Z.; Preiser, P.R.; Ho, S.Y.; Lescar, J.
Source: Self-asserted source
Guangan Hu via Scopus - Elsevier

The transcriptome of Plasmodium vivax reveals divergence and diversity of transcriptional regulation in malaria parasites

2008 | Journal article
DOI:

10.1073/pnas.0807404105

EID:

2-s2.0-55849142984
Contributors: Bozdech, Z.; Mok, S.; Hu, G.; Imwong, M.; Jaidee, A.; Russell, B.; Ginsburg, H.; Nosten, F.; Day, N.P.J.; White, N.J. et al.
Source: Self-asserted source
Guangan Hu via Scopus - Elsevier

Selection of long oligonucleotides for gene expression microarrays using weighted rank-sum strategy

2007 | Journal article
DOI:

10.1186/1471-2105-8-350

EID:

2-s2.0-36849034573
Contributors: Hu, G.; Llinás, M.; Li, J.; Preiser, P.R.; Bozdech, Z.
Source: Self-asserted source
Guangan Hu via Scopus - Elsevier

Identification of one intron loss and phylogenetic evolution of Dfak gene in the Drosophila melanogaster species group

2005 | Journal article
DOI:

10.1007/s10709-005-8693-x

EID:

2-s2.0-27144499820
Contributors: Jin, S.; Hu, G.A.; Qian, Y.H.; Zhang, L.; Zhang, J.; Qiu, G.; Zeng, Q.T.; Gui, J.F.
Source: Self-asserted source
Guangan Hu via Scopus - Elsevier

The distribution and origin of P elements in Drosophila melanogaster strains from northeast China

2003 | Journal article
EID:

2-s2.0-3843140699
Contributors: Hu, G.A.; Zeng, Q.T.; Qian, Y.H.; Li, S.T.
Source: Self-asserted source
Guangan Hu via Scopus - Elsevier
How many people are using ORCID?