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Developmental origins of adult health and disease, Pancreatic islet metabolism, Mitochondria, Type 2 diabetes, Maternal obesity
Australia

Activities

Employment (3)

University of Adelaide: Adelaide, AU

2020-02-17 to present | Senior Research Fellow and Group Leader (Robinson Research Institute)
Employment
Source: Self-asserted source
Lisa Nicholas

University of Cambridge: Cambridge, Cambridgeshire, GB

2016-01 to 2019-09-01 | C J Martin Fellow
Employment
Source: Self-asserted source
Lisa Nicholas

Lund University: Malmö, Skåne, SE

2014-01 to 2015-12 | Post-doctoral fellow
Employment
Source: Self-asserted source
Lisa Nicholas

Education and qualifications (3)

University of South Australia: Adelaide, SA, AU

2009-03 to 2013-08 | PhD
Education
Source: Self-asserted source
Lisa Nicholas

University of South Australia: Adelaide, SA, AU

2008-02 to 2008-11 | B Medical and Pharmaceutical Biotechnology (Honours)
Education
Source: Self-asserted source
Lisa Nicholas

University of Adelaide: Adelaide, SA, AU

2003-03 to 2005-11 | B Sc (Biomedical Science)
Education
Source: Self-asserted source
Lisa Nicholas

Funding (5)

The role of microRNAs in transducing the programming actions of maternal obesity on β-cell dysfunction in the offspring

2017-05 to 2018-04 | Grant
Society for Endocrinology (Bristol, GB)
Source: Self-asserted source
Lisa Nicholas

The role of microRNAs in transducing the programming actions of maternal obesity on β-cell dysfunction in the offspring and exploring their use as biomarkers

2017-02 to 2018-01 | Grant
Diabetes Research & Wellness Foundation (Hampshire, GB)
Source: Self-asserted source
Lisa Nicholas

The transgenerational epigenetic inheritance of parental obesity

2016-01 to 2019-12 | Salary award
National Health and Medical Research Council (ACT, ACT, AU)
Source: Self-asserted source
Lisa Nicholas

Delineating the role of mitochondrial transcription factor TFB2M in mitochondrial function and insulin secretion in pancreatic beta cells

2016-01 to 2016-12 | Grant
Direktör Albert Påhlssons Stiftelse (Malmö, SE)
Source: Self-asserted source
Lisa Nicholas

Delineating the role of mitochondrial transcription factor TFB2M in mitochondrial function and insulin secretion in pancreatic beta cells

2015-01 to 2015-12 | Grant
Direktör Albert Påhlssons Stiftelse (Malmö, SE)
Source: Self-asserted source
Lisa Nicholas

Works (18)

Molecular mechanisms underlying adverse effects of dexamethasone and betamethasone in the developing cardiovascular system

The FASEB Journal
2023-06 | Journal article
Contributors: Tessa A. C. Garrud; Noor E. W. D. Teulings; Youguo Niu; Katie L. Skeffington; Christian Beck; Nozomi Itani; Fiona G. Conlon; Kimberley J. Botting; Lisa M. Nicholas; Wen Tong et al.
Source: check_circle
Crossref

Understanding the Long-Lasting Effects of Fetal Nutrient Restriction versus Exposure to an Obesogenic Diet on Islet-Cell Mass and Function

Metabolites
2021-08-04 | Journal article
Contributors: Stephanie E. O’Hara; Kelly M. Gembus; Lisa M. Nicholas
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Isolating adverse effects of glucocorticoids on the embryonic cardiovascular system

The FASEB Journal
2020-07 | Journal article
Contributors: Noor E. W. D. Teulings; Tessa A. C. Garrud; Youguo Niu; Katie L. Skeffington; Christian Beck; Nozomi Itani; Fiona G. Conlon; Kimberley J. Botting; Lisa M. Nicholas; Thomas J. Ashmore et al.
Source: check_circle
Crossref

Exposure to maternal obesity programs sex differences in pancreatic islets of the offspring in mice

Diabetologia
2020-02-26 | Journal article
Contributors: Lisa M. Nicholas; Mototsugu Nagao; Laura C. Kusinski; Denise S. Fernandez-Twinn; Lena Eliasson; Susan E. Ozanne
Source: check_circle
Crossref

Early life programming in mice by maternal overnutrition: mechanistic insights and interventional approaches

Philosophical Transactions of the Royal Society B: Biological Sciences
2019-04-15 | Journal article
Contributors: Lisa M. Nicholas; Susan E. Ozanne
Source: check_circle
Crossref

Exposure to maternal obesity per se programs sex-differences in pancreatic islets of the offspring

2019-03-27 | Other
Contributors: L M Nicholas; M Nagao; L C Kusinski; D S Fernandez-Twinn; L Eliasson; S E Ozanne
Source: check_circle
Crossref

Mitochondrial transcription factor B2 is essential for mitochondrial and cellular function in pancreatic β-cells

Molecular Metabolism
2017-05 | Journal article
Source: Self-asserted source
Lisa Nicholas
grade
Preferred source (of 2)‎

Glycogen metabolism in the glucose-sensing and supply-driven β-cell

FEBS Letters
2016 | Journal article
EID:

2-s2.0-84996572984

Contributors: Andersson, L.E.; Nicholas, L.M.; Filipsson, K.; Sun, J.; Medina, A.; Al-Majdoub, M.; Fex, M.; Mulder, H.; Spégel, P.
Source: Self-asserted source
Lisa Nicholas via Scopus - Elsevier

The early origins of obesity and insulin resistance: Timing, programming and mechanisms

International Journal of Obesity
2016 | Journal article
EID:

2-s2.0-84957848273

Contributors: Nicholas, L.M.; Morrison, J.L.; Rattanatray, L.; Zhang, S.; Ozanne, S.E.; McMillen, I.C.
Source: Self-asserted source
Lisa Nicholas via Scopus - Elsevier

The Impact of Maternal Obesity and Weight Loss During the Periconceptional Period on Offspring Metabolism

Parental Obesity: Intergenerational Programming and Consequences
2016-01 | Book chapter
Source: Self-asserted source
Lisa Nicholas

Impact of maternal overnutrition on gluconeogenic factors and methylation of the phosphoenolpyruvate carboxykinase promoter in the fetal and postnatal liver

Pediatric Research
2014 | Journal article
EID:

2-s2.0-84893268732

Contributors: Rattanatray, L.; Muhlhausler, B.S.; Nicholas, L.M.; Morrison, J.L.; McMillen, I.C.
Source: Self-asserted source
Lisa Nicholas via Scopus - Elsevier

Loss of TFB1M results in mitochondrial dysfunction that leads to impaired insulin secretion and diabetes

Human Molecular Genetics
2014 | Journal article
EID:

2-s2.0-84911361474

Contributors: Sharoyko, V.V.; Abels, M.; Sun, J.; Nicholas, L.M.; Mollet, I.G.; Stamenkovic, J.A.; Göhring, I.; Malmgren, S.; Storm, P.; Fadista, J. et al.
Source: Self-asserted source
Lisa Nicholas via Scopus - Elsevier

Maternal obesity or weight loss around conception impacts hepatic fatty acid metabolism in the offspring

Obesity
2014 | Journal article
EID:

2-s2.0-84903518683

Contributors: Nicholas, L.M.; Rattanatray, L.; Morrison, J.L.; Kleemann, D.O.; Walker, S.K.; Zhang, S.; MacLaughlin, S.; McMillen, I.C.
Source: Self-asserted source
Lisa Nicholas via Scopus - Elsevier

Stress and programming of metabolic disease

Stress and Developmental Programming of Health and Disease: Beyond Phenomenology
2014 | Book
EID:

2-s2.0-84957063113

Contributors: Zhang, S.; Lie, S.; Nicholas, L.M.; Rattanatray, L.; Morrison, J.L.; McMillen, I.C.
Source: Self-asserted source
Lisa Nicholas via Scopus - Elsevier

Differential effects of exposure to maternal obesity or maternal weight loss during the periconceptional period in the sheep on insulin signalling molecules in skeletal muscle of the offspring at 4 months of age

PLoS ONE
2013 | Journal article
EID:

2-s2.0-84891339171

Contributors: Nicholas, L.M.; Morrison, J.L.; Rattanatray, L.; Ozanne, S.E.; Kleemann, D.O.; Walker, S.K.; MacLaughlin, S.M.; Zhang, S.; Martin-Gronert, M.S.; McMillen, I.C.
Source: Self-asserted source
Lisa Nicholas via Scopus - Elsevier

Differential effects of maternal obesity and weight loss in the periconceptional period on the epigenetic regulation of hepatic insulin-signaling pathways in the offspring

FASEB Journal
2013 | Journal article
EID:

2-s2.0-84883418051

Contributors: Nicholas, L.M.; Rattanatray, L.; MacLaughlin, S.M.; Ozanne, S.E.; Kleemann, D.O.; Walker, S.K.; Morrison, J.L.; Zhang, S.; Muhlhäusler, B.S.; Martin-Gronert, M.S. et al.
Source: Self-asserted source
Lisa Nicholas via Scopus - Elsevier

Perinatal nutrition and implications for lifelong health lessons from animal model studies

Australasian Medical Journal
2012 | Journal article
EID:

2-s2.0-84871955698

Contributors: McMillen, I.C.; Nicholas, L.M.; Rattanatray, L.; Zhang, S.; Lei, S.; Morrison, J.L.
Source: Self-asserted source
Lisa Nicholas via Scopus - Elsevier

Maternal obesity and the early origins of childhood obesity: Weighing up the benefits and costs of maternal weight loss in the periconceptional period for the offspring

Experimental Diabetes Research
2011 | Journal article
EID:

2-s2.0-84855566821

Contributors: Zhang, S.; Rattanatray, L.; Morrison, J.L.; Nicholas, L.M.; Lie, S.; McMillen, I.C.
Source: Self-asserted source
Lisa Nicholas via Scopus - Elsevier