Personal information

Other IDs

Scopus Author ID: 7101816660

Keywords

ALS, neurofilament, RNA

Biography

Dr Michael J. Strong is a Distinguished University Professor in the Department of Clinical Neurological Sciences at Western University. He served as the President of the Canadian Institutes of Health Research from 2018 to 2023 and prior to this, he served as the Dean of the Schulich School of Medicine & Dentistry at Western University. As a clinician-scientist with a specific research focus on amyotrophic lateral sclerosis (ALS; Lou Gehrig’s Disease), he has published over 220 peer-reviewed articles and 29 chapters, edited 4 textbooks and has given over 180 invited lectures related to his research in ALS. He was awarded the Sheila Essay Award in 2005 and the Forbes Norris Award in 2008 and is the only Canadian to have received both international awards for ALS research. He was elected as a fellow of the American Academy of Neurology in 2008. In 2009, he was elected a Fellow of the Canadian Academy of Health Sciences. His research has focused on understanding the pathogenesis of ALS, including the role of altered RNA metabolism in its genesis in addition to defining a role for altered tau metabolism in the frontotemporal spectrum disorder of ALS.

Activities

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Employment (14)

Western University: London, Ontario, CA

Professor (Department of Pathology and Laboratory Medicine)
Employment
Source: Self-asserted source
Michael J Strong

Western University: London, Ontario, CA

2001 to present | Professor (Department of Clinical Neurological Sciences)
Employment
Source: Self-asserted source
Michael J Strong

Western University: London, Ontario, CA

1994 to present | Scientist (Robarts Research Institute)
Employment
Source: Self-asserted source
Michael J Strong

Western University: London, Ontario, CA

1994 to present | Core Faculty (Graduate Program in Neuroscience)
Employment
Source: Self-asserted source
Michael J Strong

Canadian Institutes of Health Research: Ottawa, CA

2018-10 to 2023-10 | President
Employment
Source: Self-asserted source
Michael J Strong

Western University: London, Ontario, CA

2010-07 to 2018-09 | Dean (Schulich School of Medicine & Dentistry)
Employment
Source: Self-asserted source
Michael J Strong

Western University: London, Ontario, CA

2010 to 2015 | Interim Scientific Director (Robarts Research Institute)
Employment
Source: Self-asserted source
Michael J Strong

Western University: London, Ontario, CA

2000 to 2010 | Co-chair/Chief (Department of Clinical Neurological Sciences)
Employment
Source: Self-asserted source
Michael J Strong

Western University: London, Ontario, CA

2000 to 2010 | Chief (Division of Neurology, Department of Clinical Neurological Sceinces)
Employment
Source: Self-asserted source
Michael J Strong

Western University: London, Ontario, CA

1997 to 2001 | Honorary Associate Professor (School of Communication and Disorders, Faculty of Health Sciences)
Employment
Source: Self-asserted source
Michael J Strong

Western University: London, Ontario, CA

1995 to 2001 | Associate Professor (Department of Clinical Neurological Sciences)
Employment
Source: Self-asserted source
Michael J Strong

Western University: London, Ontario, CA

1994 to 2001 | Honorary Lecturer (Department of Pathology)
Employment
Source: Self-asserted source
Michael J Strong

Western University: London, Ontario, CA

1990 to 1995 | Assistant Professor (Department of Clinical Neurological Sciences)
Employment
Source: Self-asserted source
Michael J Strong

Western University: London, Ontario, CA

1990 to 1994 | Associate Scientist (Robarts Research Institute)
Employment
Source: Self-asserted source
Michael J Strong

Education and qualifications (7)

University of Alabama at Birmingham: Birmingham, US

1992 to 1992 | (CIBA Foundation Bursar) (Protein Chemistry Medothology)
Education
Source: Self-asserted source
Michael J Strong

National Institute of Neurological Disorders and Stroke: Bethesda, Maryland, US

1987 to 1990 | Research Fellowship (Laboratory of Central Nervous System Studies)
Education
Source: Self-asserted source
Michael J Strong

Armed Forces Institute of Pathology: Rawalpindi, PK

1988 to 1988
Education
Source: Self-asserted source
Michael J Strong

Western University: London, Ontario, CA

1984 to 1987 | Resident (Neurology)
Education
Source: Self-asserted source
Michael J Strong

Western University: London, Ontario, CA

1982 to 1984 | Resident (Medicine)
Education
Source: Self-asserted source
Michael J Strong

Queen's University: Kingston, Ontario, CA

1978 to 1982 | Doctor of Medicine
Education
Source: Self-asserted source
Michael J Strong

Queen's University: Kingston, Ontario, CA

1976 to 1978 | Undergraduate (Biochemistry)
Education
Source: Self-asserted source
Michael J Strong

Funding (20)

The role of differential bone marrow immune landscape in permissive tumor growth in the spine

2021-01-12 to 2023-01-11 | Grant
National Cancer Institute (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.9560012
GRANT_NUMBER: F32CA254147
Source: Self-asserted source
Michael J Strong via DimensionsWizard

Impact of altered TDP-43 function on stress granule formation and microRNA processing

2019-06-01 to 2019-11-30 | Grant
Canadian Institutes of Health Research (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.8684288
GRANT_NUMBER:

grant.8684288
Source: Self-asserted source
Michael J Strong via DimensionsWizard

Impact of altered TDP-43 function on stress granule formation and microRNA processing

2018-05-01 to 2020-12-22 | Grant
Canadian Institutes of Health Research (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.8459561
GRANT_NUMBER:

grant.8459561
Source: Self-asserted source
Michael J Strong via DimensionsWizard

Unearthing interacting nontuberculous mycobacterial, environmental, and host determinants of lung disease in the Hawai'i Islands

2017-07-15 to 2023-06-30 | Grant
Directorate for Biological Sciences (Alexandria, US)
URL: https://app.dimensions.ai/details/grant/grant.6932413
GRANT_NUMBER: 1743587
Source: Self-asserted source
Michael J Strong via DimensionsWizard

Centre for Functional and Metabolic Mapping

2016-04-01 to present | Grant
Brain Canada Foundation (Montreal, CA)
URL: https://app.dimensions.ai/details/grant/grant.13915492
GRANT_NUMBER: grant.13915492
Source: Self-asserted source
Michael J Strong via DimensionsWizard

The application of next-generation sequencing technology in identifying the genetic origins of unclassified familial disorders.

2015-05-01 to 2016-08-31 | Grant
Canadian Institutes of Health Research (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.8456805
GRANT_NUMBER:

grant.8456805
Source: Self-asserted source
Michael J Strong via DimensionsWizard

Regulation of the stress granule proteome and transcriptome by TDP-43 in ALS: biomarkers and therapeutic targets

2015-04-01 to present | Grant
Brain Canada Foundation (Montreal, CA)
URL: https://app.dimensions.ai/details/grant/grant.9458451
GRANT_NUMBER: grant.9458451
Source: Self-asserted source
Michael J Strong via DimensionsWizard

Characterization of RGNEF - a novel RNA binding protein that forms pathological aggregates in ALS.

2014-10-01 to 2015-09-30 | Grant
Canadian Institutes of Health Research (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.7661202
GRANT_NUMBER:

grant.7661202
Source: Self-asserted source
Michael J Strong via DimensionsWizard

Human cytomegalovirus in the promotion of glioblastoma multiforme pathogenesis

2013-04-01 to 2017-03-31 | Grant
National Cancer Institute (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.2358071
GRANT_NUMBER: F30CA177267
Source: Self-asserted source
Michael J Strong via DimensionsWizard

Collaborative Research: An Agent-Based Simulation Environment for Predictive Longitudinal Modeling of High School Math Performance

2011-11-15 to 2015-07-31 | Grant
Directorate for STEM Education (Alexandria, US)
URL: https://app.dimensions.ai/details/grant/grant.3127358
GRANT_NUMBER: 1119332
Source: Self-asserted source
Michael J Strong via DimensionsWizard

Cafe Scientifique on Healthy Aging

2011-09-01 to 2012-08-31 | Grant
Canadian Institutes of Health Research (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.7638961
GRANT_NUMBER:

grant.7638961
Source: Self-asserted source
Michael J Strong via DimensionsWizard

MicroRNA (miRNA) modulation of NFL mRNA degradation and translational silencing in ALS

2010-04-01 to 2013-03-31 | Grant
Canadian Institutes of Health Research (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.7661203
GRANT_NUMBER:

grant.7661203
Source: Self-asserted source
Michael J Strong via DimensionsWizard

The role of TDP-43 in regulating NFL mRNA metabolism.

2008-10-01 to 2011-09-30 | Grant
Canadian Institutes of Health Research (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.7661204
GRANT_NUMBER:

grant.7661204
Source: Self-asserted source
Michael J Strong via DimensionsWizard

Development of integrated genomic maps

2006-07-01 to 2009-06-30 | Grant
Jane Coffin Childs Memorial Fund for Medical Research (New Haven, US)
URL: https://app.dimensions.ai/details/grant/grant.100097210
GRANT_NUMBER:

61-1320
Source: Self-asserted source
Michael J Strong via DimensionsWizard

Immunomodulation influences outcome following upper and lower motor neuron injury in mouse models of amyotrophic lateral sclerosis

2006-05-01 to 2009-04-30 | Grant
Canadian Institutes of Health Research (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.7649870
GRANT_NUMBER:

grant.7649870
Source: Self-asserted source
Michael J Strong via DimensionsWizard

Protein misfolding in sporadic ALS: Proteomics, model systems and therapeutics

2005-06-01 to 2006-05-31 | Grant
Canadian Institutes of Health Research (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.7640358
GRANT_NUMBER:

grant.7640358
Source: Self-asserted source
Michael J Strong via DimensionsWizard

Neurofilamentous aggregate modulation of excitotoxicity in a transgenic mouse model of neurodegeneration

2005-05-01 to 2006-08-31 | Grant
Canadian Institutes of Health Research (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.7657714
GRANT_NUMBER:

grant.7657714
Source: Self-asserted source
Michael J Strong via DimensionsWizard

Engineered bone marrow stem cells (BMSCs) for treatment of CNS injuries and diseases

2004-10-01 to 2009-09-30 | Grant
Canadian Institutes of Health Research (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.7656104
GRANT_NUMBER:

grant.7656104
Source: Self-asserted source
Michael J Strong via DimensionsWizard

Intermediate filament expression in sporadic amyotrophic lateral sclerosis (ALS)

2001-10-01 to 2003-09-30 | Grant
Canadian Institutes of Health Research (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.7661205
GRANT_NUMBER:

grant.7661205
Source: Self-asserted source
Michael J Strong via DimensionsWizard

Tissue Banking and Cryopreservation of Massive Allografts

1995-09-01 to 1996-08-31 | Grant
Council for International Exchange of Scholars (Washington D.C., US)
URL: https://app.dimensions.ai/details/grant/grant.9901652
GRANT_NUMBER: grant.9901652
Source: Self-asserted source
Michael J Strong via DimensionsWizard

Peer review (2 reviews for 2 publications/grants)

Review activity for Acta neuropathologica communications. (1)
Review activity for The lancet. (1)
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