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Works (25)

C9ORF72 Deficiency Results in Neurodegeneration in the Zebrafish Retina

The Journal of Neuroscience
2024-06-19 | Journal article
Contributors: Natalia Jaroszynska; Andrea Salzinger; Themistoklis M. Tsarouchas; Catherina G. Becker; Thomas Becker; David A. Lyons; Ryan B. MacDonald; Marcus Keatinge
Source: check_circle
Crossref

C9ORF72 deficiency results in degeneration of the zebrafish retina in vivo

bioRxiv
2023 | Other
EID:

2-s2.0-85178619047

Part of ISSN: 26928205
Contributors: Jaroszynska, N.; Salzinger, A.; Tsarouchas, T.M.; Becker, C.G.; Becker, T.; Lyons, D.A.; MacDonald, R.B.; Keatinge, M.
Source: Self-asserted source
Marcus Keatinge via Scopus - Elsevier

Rapid Testing of Gene Function in Axonal Regeneration After Spinal Cord Injury Using Larval Zebrafish

Methods in Molecular Biology
2023 | Book chapter
EID:

2-s2.0-85149544558

Part of ISSN: 19406029 10643745
Contributors: Drake, L.K.; Keatinge, M.; Tsarouchas, T.M.; Becker, C.G.; Lyons, D.A.; Becker, T.
Source: Self-asserted source
Marcus Keatinge via Scopus - Elsevier

Unexpected phenotypic and molecular changes of combined glucocerebrosidase and acid sphingomyelinase deficiency

DMM Disease Models and Mechanisms
2023 | Journal article
EID:

2-s2.0-85159729312

Part of ISSN: 17548411 17548403
Contributors: Keatinge, M.; Gegg, M.E.; Watson, L.; Mortiboys, H.; Li, N.; Dunning, M.; Ailani, D.; Bui, H.; van Rens, A.; Lefeber, D.J. et al.
Source: Self-asserted source
Marcus Keatinge via Scopus - Elsevier
grade
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Ankk1 Loss of Function Disrupts Dopaminergic Pathways in Zebrafish

Frontiers in Neuroscience
2022 | Journal article
EID:

2-s2.0-85125078921

Part of ISSN: 1662453X 16624548
Contributors: Leggieri, A.; García-González, J.; Torres-Perez, J.V.; Havelange, W.; Hosseinian, S.; Mech, A.M.; Keatinge, M.; Busch-Nentwich, E.M.; Brennan, C.H.
Source: Self-asserted source
Marcus Keatinge via Scopus - Elsevier

GCH1 Deficiency Activates Brain Innate Immune Response and Impairs Tyrosine Hydroxylase Homeostasis

Journal of Neuroscience
2022 | Journal article
EID:

2-s2.0-85123878820

Part of ISSN: 15292401 02706474
Contributors: Larbalestier, H.; Keatinge, M.; Watson, L.; White, E.; Gowda, S.; Wei, W.; Koler, K.; Semenova, S.A.; Elkin, A.M.; Rimmer, N. et al.
Source: Self-asserted source
Marcus Keatinge via Scopus - Elsevier

A unique macrophage subpopulation signals directly to progenitor cells to promote regenerative neurogenesis in the zebrafish spinal cord

Developmental Cell
2021 | Journal article
EID:

2-s2.0-85107154076

Part of ISSN: 18781551 15345807
Contributors: Cavone, L.; McCann, T.; Drake, L.K.; Aguzzi, E.A.; Oprişoreanu, A.-M.; Pedersen, E.; Sandi, S.; Selvarajah, J.; Tsarouchas, T.M.; Wehner, D. et al.
Source: Self-asserted source
Marcus Keatinge via Scopus - Elsevier

CRISPR gRNA phenotypic screening in zebrafish reveals pro-regenerative genes in spinal cord injury

PLoS Genetics
2021 | Journal article
EID:

2-s2.0-85105115265

Part of ISSN: 15537404 15537390
Contributors: Keatinge, M.; Tsarouchas, T.M.; Munir, T.; Porter, N.J.; Larraz, J.; Gianni, D.; Tsai, H.-H.; Becker, C.G.; Lyons, D.A.; Becker, T.
Source: Self-asserted source
Marcus Keatinge via Scopus - Elsevier

PINK1 deficiency impairs adult neurogenesis of dopaminergic neurons

Scientific Reports
2021 | Journal article
EID:

2-s2.0-85103190338

Part of ISSN: 20452322
Contributors: Brown, S.J.; Boussaad, I.; Jarazo, J.; Fitzgerald, J.C.; Antony, P.; Keatinge, M.; Blechman, J.; Schwamborn, J.C.; Krüger, R.; Placzek, M. et al.
Source: Self-asserted source
Marcus Keatinge via Scopus - Elsevier

A Unique Macrophage Subpopulation Signals Directly to Progenitor Cells to Promote Regenerative Neurogenesis in the Zebrafish Spinal Cord

SSRN
2020 | Other
EID:

2-s2.0-85110298304

Part of ISSN: 15565068
Contributors: Cavone, L.; McCann, T.; Drake, L.K.; Aguzzi, E.A.; Oprişoreanu, A.-M.; Pedersen, E.; Sandi, S.; Selvarajah, J.; Tsarouchas, T.M.; Wehner, D. et al.
Source: Self-asserted source
Marcus Keatinge via Scopus - Elsevier

Acid Sphingomyelinase Deficiency Normalizes Neuronal Function in GCase Deficiency - Unexpected Biological Rescue Effect of Combined Genetic Risk Factors for Parkinson’s Disease

Research Square
2020 | Other
EID:

2-s2.0-85166727460

Contributors: Keatinge, M.; Gegg, M.E.; Watson, L.; Mortiboys, H.; Bui, H.; Lefeber, D.; Van Rens, A.; MacDonald, R.; Schapira, A.; Bandmann, O.
Source: Self-asserted source
Marcus Keatinge via Scopus - Elsevier

Phenotypic screening using synthetic CRISPR gRNAs reveals pro-regenerative genes in spinal cord injury

bioRxiv
2020 | Other
EID:

2-s2.0-85098901623

Part of ISSN: 26928205
Contributors: Keatinge, M.; Tsarouchas, T.M.; Munir, T.; Larraz, J.; Gianni, D.; Tsai, H.-H.; Becker, C.G.; Lyons, D.A.; Becker, T.
Source: Self-asserted source
Marcus Keatinge via Scopus - Elsevier
grade
Preferred source (of 2)‎

RNA-seq analysis and compound screening highlight multiple signalling pathways regulating secondary cell death after acute CNS injury in vivo

Biology Open
2020 | Journal article
EID:

2-s2.0-85086231811

Part of ISSN: 20466390
Contributors: Herzog, C.; Greenald, D.; Larraz, J.; Keatinge, M.; Herrgen, L.
Source: Self-asserted source
Marcus Keatinge via Scopus - Elsevier

Ablation of the pro-inflammatory master regulator miR-155 does not mitigate neuroinflammation or neurodegeneration in a vertebrate model of Gaucher's disease

Neurobiology of Disease
2019 | Journal article
EID:

2-s2.0-85064324531

Part of ISSN: 1095953X 09699961
Contributors: Watson, L.; Keatinge, M.; Gegg, M.; Bai, Q.; Sandulescu, M.C.; Vardi, A.; Futerman, A.H.; Schapira, A.H.V.; Burton, E.A.; Bandmann, O.
Source: Self-asserted source
Marcus Keatinge via Scopus - Elsevier

Brain tumours repurpose endogenous neuron to microglia signalling mechanisms to promote their own proliferation

eLife
2019 | Journal article
EID:

2-s2.0-85071346329

Part of ISSN: 2050084X
Contributors: Chia, K.; Keatinge, M.; Mazzolini, J.; Sieger, D.
Source: Self-asserted source
Marcus Keatinge via Scopus - Elsevier

Loss of acid sphingomyelinase ameliorates disease progression in a vertebrate model of Glucocerebrosidase deficiency

bioRxiv
2019 | Other
EID:

2-s2.0-85095635335

Part of ISSN: 26928205
Contributors: Keatinge, M.; Gegg, M.E.; Watson, L.; Mortiboys, H.; Bui, H.; van Rens, A.; Lefeber, D.J.; MacDonald, R.B.; Schapira, A.H.V.; Bandmann, O.
Source: Self-asserted source
Marcus Keatinge via Scopus - Elsevier

Rapid clearance of cellular debris by microglia limits secondary neuronal cell death after brain injury in vivo

Development (Cambridge)
2019 | Journal article
EID:

2-s2.0-85065939223

Part of ISSN: 14779129 09501991
Contributors: Herzog, C.; Garcia, L.P.; Keatinge, M.; Greenald, D.; Moritz, C.; Peri, F.; Herrgen, L.
Source: Self-asserted source
Marcus Keatinge via Scopus - Elsevier

Restriction of mitochondrial calcium overload by mcu inactivation renders a neuroprotective effect in zebrafish models of Parkinson’s disease

Biology Open
2019 | Journal article
EID:

2-s2.0-85074825821

Part of ISSN: 20466390
Contributors: Soman, S.K.; Bazała, M.; Keatinge, M.; Bandmann, O.; Kuznicki, J.
Source: Self-asserted source
Marcus Keatinge via Scopus - Elsevier
grade
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Dynamic control of proinflammatory cytokines Il-1β and Tnf-α by macrophages in zebrafish spinal cord regeneration

Nature Communications
2018 | Journal article
EID:

2-s2.0-85056096803

Part of ISSN: 20411723
Contributors: Tsarouchas, T.M.; Wehner, D.; Cavone, L.; Munir, T.; Keatinge, M.; Lambertus, M.; Underhill, A.; Barrett, T.; Kassapis, E.; Ogryzko, N. et al.
Source: Self-asserted source
Marcus Keatinge via Scopus - Elsevier

Dynamic control of proinflammatory cytokines Il-1β and Tnf-α by macrophages is necessary for functional spinal cord regeneration in zebrafish

bioRxiv
2018 | Other
EID:

2-s2.0-85095658828

Part of ISSN: 26928205
Contributors: Tsarouchas, T.M.; Wehner, D.; Cavone, L.; Munir, T.; Keatinge, M.; Lambertus, M.; Underhill, A.; Barrett, T.; Kassapis, E.; Ogryzko, N. et al.
Source: Self-asserted source
Marcus Keatinge via Scopus - Elsevier

The NAD+ Precursor Nicotinamide Riboside Rescues Mitochondrial Defects and Neuronal Loss in iPSC and Fly Models of Parkinson's Disease

Cell Reports
2018 | Journal article
EID:

2-s2.0-85047488499

Part of ISSN: 22111247
Contributors: Schöndorf, D.C.; Ivanyuk, D.; Baden, P.; Sanchez-Martinez, A.; De Cicco, S.; Yu, C.; Giunta, I.; Schwarz, L.K.; Di Napoli, G.; Panagiotakopoulou, V. et al.
Source: Self-asserted source
Marcus Keatinge via Scopus - Elsevier

Inhibition of the mitochondrial calcium uniporter rescues dopaminergic neurons in pink1<sup>−/−</sup> zebrafish

European Journal of Neuroscience
2017 | Journal article
EID:

2-s2.0-85007452263

Part of ISSN: 14609568 0953816X
Contributors: Soman, S.; Keatinge, M.; Moein, M.; Da Costa, M.; Mortiboys, H.; Skupin, A.; Sugunan, S.; Bazala, M.; Kuznicki, J.; Bandmann, O.
Source: Self-asserted source
Marcus Keatinge via Scopus - Elsevier

Lysosomal and phagocytic activity is increased in astrocytes during disease progression in the SOD1 (G93A) mouse model of amyotrophic lateral sclerosis.

2015 | Journal article
Contributors: Baker DJ; Blackburn DJ; Keatinge M; Sokhi D; Viskaitis P; Heath PR; Ferraiuolo L; Kirby J; Shaw PJ
Source: Self-asserted source
Marcus Keatinge via Europe PubMed Central
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Glucocerebrosidase 1 deficient Danio rerio mirror key pathological aspects of human Gaucher disease and provide evidence of early microglial activation preceding alpha-synuclein-independent neuronal cell death.

2015-12 | Journal article
Contributors: Keatinge M; Bui H; Menke A; Chen YC; Sokol AM; Bai Q; Ellett F; Da Costa M; Burke D; Gegg M et al.
Source: Self-asserted source
Marcus Keatinge via Europe PubMed Central
grade
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TigarB causes mitochondrial dysfunction and neuronal loss in PINK1 deficiency.

2013-12 | Journal article
Contributors: Flinn LJ; Keatinge M; Bretaud S; Mortiboys H; Matsui H; De Felice E; Woodroof HI; Brown L; McTighe A; Soellner R et al.
Source: Self-asserted source
Marcus Keatinge via Europe PubMed Central
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Peer review (2 reviews for 1 publication/grant)

Review activity for Neurobiology of disease. (2)