Personal information

Inflammatory Bowel disease, microbiota, Crohn's disease, Ulcerative Colitis, Biomarker

Biography

I obtained a degree in Biology from the University Autonoma of Barcelona in 2002. PhD from the Rovira i Virgili University (URV) in 2007. I developed my postdoctoral stage at the Weastmead Millenium Institute in Sydney, Australia. During this stage, I participated as a researcher in the international project "Phylogeny as a basis for Molecular Identification of Pathogenic Fungi" Grant number 3352303 and as a professor of a postgraduate course at the University of Sydney. Currently, I am I3 Senior Scientist (former Ramón y Cajal tenure) at the Research Group on Diabetes and Associated Metabolic Alterations at the Health Institute Pere Virgili (IISPV, Tarragona). My main line of research was to identify the key factors that intervene in the triggering of the innate immune response of adipose tissue in local or systemic inflammation in the context of obesity and Crohn's disease. I led a project associated with my RyC contract (RYC-2013-13186) and a national project (PI15/00143), which had produced the fruit of 6 scientific publications in prestigious journals in its area and two patents (PCT/EP2019/051157; EP17382615.7). I have been granted a national project (PI18/00037) to evaluate the role of peri-intestinal adipose tissue as a barrier to bacterial translocation presented by patients with Crohn's disease and its immunomodulatory function mediated by adipose-derived stem cells which so far has produced two publications in prestigious journals in its area and one more is under review. I also received a grant prize from the European Crohn's and Colitis Organization (ECCO) to perform an integrative analysis of DNA methylation and RNA sequencing in human adipose-derived stem cells of Crohn's disease patients with different clinical activities. In addition, I participated as a collaborating researcher in an interciber project (PIE14/00045), a project of the Marató de TV3 (PV17013S) and Caixaimpulse project (SUCCIPRO). Recently, I have created my own research group in Inflammatory Bowel Diseases (IBoDi) at IISPV (https://www.iispv.cat/grup/grup-de-recerca-en-malalties-inflamatories-intestinals/). In terms of teaching ability, I am directing two doctoral thesis and I also directed 3 Master's final projects and 6 final degree projects (URV and University of Barcelona) in the last 5 years. I am an associate professor in the Department of Biochemistry and Biotechnology at the URV. In reference to institutional responsibilities, I am part of the Steering Committee HRS4R and the Committee of Seminars and Training of the IISPV. In the last years, I participate in several acts of scientific dissemination (European Research night, 11th of February, Pint of Science, Talks in open school health program of the city of Reus, schools and high schools,...) and currently, I am a member of the board of directors of the scientific dissemination association, DivulgaTarragona (https://divulgatgn.wordpress.com/).

Activities

Employment (1)

Intituto de Investigaciones Sanitarias Pere Virgili: Tarragona, Cataluña, ES

2014-10-23 to present | Stabilized I3 Researcher (former RyC) (Nutrition and Metabolism. Gastroenterology.)
Employment
Source: Self-asserted source
Carolina Serena

Education and qualifications (2)

Universitat Rovira i Virgili: Tarragona, Catalunya, ES

2003-09-01 to 2007-07-19 | PhD (Microbiology)
Education
Source: Self-asserted source
Carolina Serena

University Autonoma of Barcelona: Barcelona, ES

2002-01 | Biologist
Education
Source: Self-asserted source
Carolina Serena

Professional activities (3)

Societat Catalana de Digestologia: Barcelona, Catalunya, ES

Membership
Source: Self-asserted source
Carolina Serena

Grupo Español de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa: Bilbao, Basque, ES

2019-01-01 to present
Membership
Source: Self-asserted source
Carolina Serena

European Crohn's and Colitis Organisation: Wien, Wien, AT

2016-01-01 to present
Membership
Source: Self-asserted source
Carolina Serena

Funding (6)

VESICULAS EXTRACELULARES TOLEROGENICAS DE CELULAS MADRE PARA RESTAURAR EL PAPEL PROTECTOR DEL TEJIDO ADIPOSO MESENTERICO EN LA INFLAMACION INTESTINAL EN LA ENFERMEDAD DE CROHN

2024-09 to 2027-12 | Grant
Ministerio de Ciencia, Innovación y Universidades (Madrid, ES)
Source: Self-asserted source
Carolina Serena

Bases moleculares de la actividad del browning en el tejido adiposo mesentérico de enfermos de Crohn: estableciendo las bases para futuras terapias y seguimiento.

2024-01 to 2025-01 | Grant
Grupo Español de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa (Madrid, ES)
Source: Self-asserted source
Carolina Serena

Succinato, un metabolito derivado de la microbiota, marcador de actividad en la Enfermedad de Crohn

2022-01 to 2023-01 | Award
I beca Clinica Galapagos-GETECCU (Madrid, ES)
Source: Self-asserted source
Carolina Serena

Peri-lesional adipose tissue (creeping fat) as an immune-modulating element of intestinal dysbiosis in Crohn's disease

2018-01 to 2022-01 | Grant
Instituto de Salud Carlos III (Madrid, ES)
GRANT_NUMBER:

PI18/00037

Source: Self-asserted source
Carolina Serena

An integrative analysis of DNA methylation and RNA-Seq data in human adipose-stem cells of Crohn’s disease patients with different clinical activity

2018-01 to 2019-06 | Grant
European Crohn's and Colitis Organization (Vienn, AT)
GRANT_NUMBER:

ECCO grant to CS

Source: Self-asserted source
Carolina Serena

Mechanistic basis for the distinct inflammatory profile in obese and Crohn’s disease subjects: searching for novel therapeutic approaches.

2016-01 to 2019-01 | Grant
Instituto de Salud Carlos III (Madrid, Madrid, ES)
GRANT_NUMBER:

PI15/00143

Source: Self-asserted source
Carolina Serena

Peer review (2 reviews for 2 publications/grants)

Review activity for Clinical epigenetics (1)
Review activity for Gastroenterología y hepatología. (1)