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Works (44)

Selective SIRPα blockade reverses tumor T cell exclusion and overcomes cancer immunotherapy resistance.

The Journal of clinical investigation
2020-11-01 | Journal article
Source: Self-asserted source
Nicolas Poirier

Interleukin-7/Interferon axis drives T-cell and salivary gland epithelial cell interactions in Sjögren's syndrome.

Arthritis & rheumatology (Hoboken, N.J.)
2020-10-15 | Journal article
Source: Self-asserted source
Nicolas Poirier

Selective Costimulation Blockade With Antagonist Anti-CD28 Therapeutics in Transplantation.

Transplantation
2019-09-01 | Journal article
Source: Self-asserted source
Nicolas Poirier

Interleukin-7 receptor blockade by an anti-CD127 monoclonal antibody in nonhuman primate kidney transplantation.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
2019-08-14 | Journal article
Source: Self-asserted source
Nicolas Poirier
grade
Preferred source (of 2)‎

SIRPα/CD47 axis controls the maintenance of transplant tolerance sustained by myeloid-derived suppressor cells.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
2019-07-08 | Journal article
Source: Self-asserted source
Nicolas Poirier

IL-7 receptor influences anti-TNF responsiveness and T cell gut homing in inflammatory bowel disease.

The Journal of clinical investigation
2019-04-02 | Journal article
Source: Self-asserted source
Nicolas Poirier

Full antagonist of the IL-7 receptor suppresses chronic inflammation in non-human primate models by controlling antigen-specific memory T cells.

Cell stress
2018-12-10 | Journal article
Source: Self-asserted source
Nicolas Poirier

IL-7 receptor blockade blunts antigen-specific memory T cell responses and chronic inflammation in primates.

Nature communications
2018-10-26 | Journal article
Source: Self-asserted source
Nicolas Poirier

CD28 blockade controls T cell activation to prevent graft-versus-host disease in primates.

The Journal of clinical investigation
2018-08-13 | Journal article
Source: Self-asserted source
Nicolas Poirier

Dynamic human immune and tumour cells cross-talk in PDX-humanised mice warrants checkpoint inhibitor cancer immunotherapies assessment.

Gut
2018-04-26 | Journal article
Source: Self-asserted source
Nicolas Poirier

MHC class I diversity of olive baboons (Papio anubis) unravelled by next-generation sequencing.

Immunogenetics
2018-02-24 | Journal article
Source: Self-asserted source
Nicolas Poirier

Antagonist Anti-CD28 Therapeutics for the Treatment of Autoimmune Disorders.

Antibodies (Basel, Switzerland)
2017-11-21 | Journal article
Source: Self-asserted source
Nicolas Poirier

Prevention of lupus nephritis development in NZB/NZW mice by selective blockade of CD28.

European journal of immunology
2017-07-10 | Journal article
Source: Self-asserted source
Nicolas Poirier

Inhibition of effector antigen-specific T cells by intradermal administration of heme oxygenase-1 inducers.

Journal of autoimmunity
2017-03-23 | Journal article
Source: Self-asserted source
Nicolas Poirier

A quick and robust MHC typing method for free-ranging and captive primate species.

Immunogenetics
2017-01-13 | Journal article
Source: Self-asserted source
Nicolas Poirier

First-in-Human Study in Healthy Subjects with FR104, a Pegylated Monoclonal Antibody Fragment Antagonist of CD28.

Journal of immunology (Baltimore, Md. : 1950)
2016-11-14 | Journal article
Source: Self-asserted source
Nicolas Poirier

Comparative Analysis of piggyBac, CRISPR/Cas9 and TALEN Mediated BAC Transgenesis in the Zygote for the Generation of Humanized SIRPA Rats.

Scientific reports
2016-08-17 | Journal article
Source: Self-asserted source
Nicolas Poirier

Anti-CD28 Antibody and Belatacept Exert Differential Effects on Mechanisms of Renal Allograft Rejection.

Journal of the American Society of Nephrology : JASN
2016-05-09 | Journal article
Source: Self-asserted source
Nicolas Poirier

Selective CD28 antagonist prevents Aldara-induced skin inflammation in non-human primates.

Experimental dermatology
2016-02-10 | Journal article
Source: Self-asserted source
Nicolas Poirier

Clinical efficacy of a new CD28-targeting antagonist of T cell co-stimulation in a non-human primate model of collagen-induced arthritis.

Clinical and experimental immunology
2015-12-16 | Journal article
Source: Self-asserted source
Nicolas Poirier

Selective CD28 Antagonist Blunts Memory Immune Responses and Promotes Long-Term Control of Skin Inflammation in Nonhuman Primates.

Journal of immunology (Baltimore, Md. : 1950)
2015-11-23 | Journal article
Source: Self-asserted source
Nicolas Poirier

Co-Stimulatory Blockade of the CD28/CD80-86/CTLA-4 Balance in Transplantation: Impact on Memory T Cells?

Frontiers in immunology
2015-08-10 | Journal article
Source: Self-asserted source
Nicolas Poirier

Correction: Selective Blockade of CD28-Mediated T Cell Costimulation Protects Rhesus Monkeys against Acute Fatal Experimental Autoimmune Encephalomyelitis.

Journal of immunology (Baltimore, Md. : 1950)
2015-07-01 | Journal article
Source: Self-asserted source
Nicolas Poirier

Bortezomib, C1-inhibitor and plasma exchange do not prolong the survival of multi-transgenic GalT-KO pig kidney xenografts in baboons.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
2015-02-01 | Journal article
Source: Self-asserted source
Nicolas Poirier

Selective blockade of CD28-mediated T cell costimulation protects rhesus monkeys against acute fatal experimental autoimmune encephalomyelitis.

Journal of immunology (Baltimore, Md. : 1950)
2015-01-14 | Journal article
Source: Self-asserted source
Nicolas Poirier

FR104, an antagonist anti-CD28 monovalent fab' antibody, prevents alloimmunization and allows calcineurin inhibitor minimization in nonhuman primate renal allograft.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
2014-12-08 | Journal article
Source: Self-asserted source
Nicolas Poirier

Advantages of Papio anubis for preclinical testing of immunotoxicity of candidate therapeutic antagonist antibodies targeting CD28.

mAbs
2014-03-05 | Journal article
Source: Self-asserted source
Nicolas Poirier

Targeting CD28, CTLA-4 and PD-L1 costimulation differentially controls immune synapses and function of human regulatory and conventional T-cells.

PloS one
2013-12-23 | Journal article
Source: Self-asserted source
Nicolas Poirier

Antagonist properties of monoclonal antibodies targeting human CD28: role of valency and the heavy-chain constant domain.

mAbs
2012-12-05 | Journal article
Source: Self-asserted source
Nicolas Poirier

Gene transfer of human CD40Ig does not prevent rejection in a non-human primate kidney allotransplantation model.

Transplant immunology
2012-10-23 | Journal article
Source: Self-asserted source
Nicolas Poirier

Preclinical efficacy and immunological safety of FR104, an antagonist anti-CD28 monovalent Fab' antibody.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
2012-07-03 | Journal article
Source: Self-asserted source
Nicolas Poirier

CD28-specific immunomodulating antibodies: what can be learned from experimental models?

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
2012-04-04 | Journal article
Source: Self-asserted source
Nicolas Poirier

Control of transplant tolerance and intragraft regulatory T cell localization by myeloid-derived suppressor cells and CCL5.

Journal of immunology (Baltimore, Md. : 1950)
2012-03-26 | Journal article
Source: Self-asserted source
Nicolas Poirier

Transplant tolerance is associated with reduced expression of cystathionine-γ-lyase that controls IL-12 production by dendritic cells and TH-1 immune responses.

Blood
2012-01-19 | Journal article
Source: Self-asserted source
Nicolas Poirier

Xenotransplantation of galactosyl-transferase knockout, CD55, CD59, CD39, and fucosyl-transferase transgenic pig kidneys into baboons.

Transplantation proceedings
2011-11-01 | Journal article
Source: Self-asserted source
Nicolas Poirier

Antibody-mediated depletion of lymphocyte-activation gene-3 (LAG-3(+) )-activated T lymphocytes prevents delayed-type hypersensitivity in non-human primates.

Clinical and experimental immunology
2011-02-24 | Journal article
Source: Self-asserted source
Nicolas Poirier

A more selective costimulatory blockade of the CD28-B7 pathway.

Transplant international : official journal of the European Society for Organ Transplantation
2010-10-21 | Journal article
Source: Self-asserted source
Nicolas Poirier

Alternatives to calcineurin inhibition in renal transplantation: belatacept, the first co-stimulation blocker.

Immunotherapy
2010-09-01 | Journal article
Source: Self-asserted source
Nicolas Poirier

Recombinant human C1-inhibitor prevents acute antibody-mediated rejection in alloimmunized baboons.

Kidney international
2010-03-24 | Journal article
Source: Self-asserted source
Nicolas Poirier

Inducing CTLA-4-dependent immune regulation by selective CD28 blockade promotes regulatory T cells in organ transplantation.

Science translational medicine
2010-02-01 | Journal article
Source: Self-asserted source
Nicolas Poirier

Depleting T-cell subpopulations in organ transplantation.

Transplant international : official journal of the European Society for Organ Transplantation
2008-10-30 | Journal article
Source: Self-asserted source
Nicolas Poirier

Myeloid-derived suppressor cells accumulate in kidney allograft tolerance and specifically suppress effector T cell expansion.

Journal of immunology (Baltimore, Md. : 1950)
2008-06-01 | Journal article
Source: Self-asserted source
Nicolas Poirier

Recombinant human C1-inhibitor inhibits cytotoxicity induced by allo- and xenoantibodies.

Transplantation proceedings
2008-03-01 | Journal article
Source: Self-asserted source
Nicolas Poirier

Acute humoral rejection of renal transplants in alloimmunized pigs.

The Journal of surgical research
2007-03-13 | Journal article
Source: Self-asserted source
Nicolas Poirier

Peer review (1 review for 1 publication/grant)

Review activity for Nature communications (1)