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Selective SIRPα blockade reverses tumor T cell exclusion and overcomes cancer immunotherapy resistance.

The Journal of clinical investigation
2020-11-01 | Journal article
DOI: 10.1172/jci135528
PMID: 33074246
Source: Self-asserted source
Nicolas Poirier

Interleukin-7/Interferon axis drives T-cell and salivary gland epithelial cell interactions in Sjögren's syndrome.

Arthritis & rheumatology (Hoboken, N.J.)
2020-10-15 | Journal article
DOI: 10.1002/art.41558
PMID: 33058491
Source: Self-asserted source
Nicolas Poirier

Selective Costimulation Blockade With Antagonist Anti-CD28 Therapeutics in Transplantation.

Transplantation
2019-09-01 | Journal article
DOI: 10.1097/tp.0000000000002740
PMID: 30951014
Source: Self-asserted source
Nicolas Poirier

Interleukin-7 receptor blockade by an anti-CD127 monoclonal antibody in nonhuman primate kidney transplantation.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
2019-08-14 | Journal article
DOI: 10.1111/ajt.15543
PMID: 31344323
Source: Self-asserted source
Nicolas Poirier
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SIRPα/CD47 axis controls the maintenance of transplant tolerance sustained by myeloid-derived suppressor cells.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
2019-07-08 | Journal article
DOI: 10.1111/ajt.15497
PMID: 31207067
Source: Self-asserted source
Nicolas Poirier

IL-7 receptor influences anti-TNF responsiveness and T cell gut homing in inflammatory bowel disease.

The Journal of clinical investigation
2019-04-02 | Journal article
DOI: 10.1172/jci121668
PMID: 30939120
PMC: PMC6486337
Source: Self-asserted source
Nicolas Poirier

Full antagonist of the IL-7 receptor suppresses chronic inflammation in non-human primate models by controlling antigen-specific memory T cells.

Cell stress
2018-12-10 | Journal article
DOI: 10.15698/cst2018.12.168
PMID: 31225460
PMC: PMC6551675
Source: Self-asserted source
Nicolas Poirier

IL-7 receptor blockade blunts antigen-specific memory T cell responses and chronic inflammation in primates.

Nature communications
2018-10-26 | Journal article
DOI: 10.1038/s41467-018-06804-y
PMID: 30367166
PMC: PMC6203796
Source: Self-asserted source
Nicolas Poirier

CD28 blockade controls T cell activation to prevent graft-versus-host disease in primates.

The Journal of clinical investigation
2018-08-13 | Journal article
DOI: 10.1172/jci98793
PMID: 30102255
PMC: PMC6118599
Source: Self-asserted source
Nicolas Poirier

Dynamic human immune and tumour cells cross-talk in PDX-humanised mice warrants checkpoint inhibitor cancer immunotherapies assessment.

Gut
2018-04-26 | Journal article
DOI: 10.1136/gutjnl-2018-316467
PMID: 29700013
Source: Self-asserted source
Nicolas Poirier

MHC class I diversity of olive baboons (Papio anubis) unravelled by next-generation sequencing.

Immunogenetics
2018-02-24 | Journal article
DOI: 10.1007/s00251-018-1053-7
PMID: 29478145
PMC: PMC6006219
Source: Self-asserted source
Nicolas Poirier

Antagonist Anti-CD28 Therapeutics for the Treatment of Autoimmune Disorders.

Antibodies (Basel, Switzerland)
2017-11-21 | Journal article
DOI: 10.3390/antib6040019
PMID: 31548534
PMC: PMC6698823
Source: Self-asserted source
Nicolas Poirier

Prevention of lupus nephritis development in NZB/NZW mice by selective blockade of CD28.

European journal of immunology
2017-07-10 | Journal article
DOI: 10.1002/eji.201746923
PMID: 28631301
Source: Self-asserted source
Nicolas Poirier

Inhibition of effector antigen-specific T cells by intradermal administration of heme oxygenase-1 inducers.

Journal of autoimmunity
2017-03-23 | Journal article
DOI: 10.1016/j.jaut.2017.03.005
PMID: 28342735
Source: Self-asserted source
Nicolas Poirier

A quick and robust MHC typing method for free-ranging and captive primate species.

Immunogenetics
2017-01-13 | Journal article
DOI: 10.1007/s00251-016-0968-0
PMID: 28084496
PMC: PMC5350218
Source: Self-asserted source
Nicolas Poirier

First-in-Human Study in Healthy Subjects with FR104, a Pegylated Monoclonal Antibody Fragment Antagonist of CD28.

Journal of immunology (Baltimore, Md. : 1950)
2016-11-14 | Journal article
DOI: 10.4049/jimmunol.1601538
PMID: 27849166
Source: Self-asserted source
Nicolas Poirier

Comparative Analysis of piggyBac, CRISPR/Cas9 and TALEN Mediated BAC Transgenesis in the Zygote for the Generation of Humanized SIRPA Rats.

Scientific reports
2016-08-17 | Journal article
DOI: 10.1038/srep31455
PMID: 27530248
PMC: PMC4987655
Source: Self-asserted source
Nicolas Poirier

Anti-CD28 Antibody and Belatacept Exert Differential Effects on Mechanisms of Renal Allograft Rejection.

Journal of the American Society of Nephrology : JASN
2016-05-09 | Journal article
DOI: 10.1681/asn.2015070774
PMID: 27160407
PMC: PMC5118475
Source: Self-asserted source
Nicolas Poirier

Selective CD28 antagonist prevents Aldara-induced skin inflammation in non-human primates.

Experimental dermatology
2016-02-10 | Journal article
DOI: 10.1111/exd.12891
PMID: 26513536
Source: Self-asserted source
Nicolas Poirier

Clinical efficacy of a new CD28-targeting antagonist of T cell co-stimulation in a non-human primate model of collagen-induced arthritis.

Clinical and experimental immunology
2015-12-16 | Journal article
DOI: 10.1111/cei.12739
PMID: 26540618
Source: Self-asserted source
Nicolas Poirier

Selective CD28 Antagonist Blunts Memory Immune Responses and Promotes Long-Term Control of Skin Inflammation in Nonhuman Primates.

Journal of immunology (Baltimore, Md. : 1950)
2015-11-23 | Journal article
DOI: 10.4049/jimmunol.1501810
PMID: 26597009
Source: Self-asserted source
Nicolas Poirier

Co-Stimulatory Blockade of the CD28/CD80-86/CTLA-4 Balance in Transplantation: Impact on Memory T Cells?

Frontiers in immunology
2015-08-10 | Journal article
DOI: 10.3389/fimmu.2015.00411
PMID: 26322044
PMC: PMC4532816
Source: Self-asserted source
Nicolas Poirier

Correction: Selective Blockade of CD28-Mediated T Cell Costimulation Protects Rhesus Monkeys against Acute Fatal Experimental Autoimmune Encephalomyelitis.

Journal of immunology (Baltimore, Md. : 1950)
2015-07-01 | Journal article
DOI: 10.4049/jimmunol.1501150
PMID: 26138639
Source: Self-asserted source
Nicolas Poirier

Bortezomib, C1-inhibitor and plasma exchange do not prolong the survival of multi-transgenic GalT-KO pig kidney xenografts in baboons.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
2015-02-01 | Journal article
DOI: 10.1111/ajt.12988
PMID: 25612490
PMC: PMC4306235
Source: Self-asserted source
Nicolas Poirier

Selective blockade of CD28-mediated T cell costimulation protects rhesus monkeys against acute fatal experimental autoimmune encephalomyelitis.

Journal of immunology (Baltimore, Md. : 1950)
2015-01-14 | Journal article
DOI: 10.4049/jimmunol.1402563
PMID: 25589073
Source: Self-asserted source
Nicolas Poirier

FR104, an antagonist anti-CD28 monovalent fab' antibody, prevents alloimmunization and allows calcineurin inhibitor minimization in nonhuman primate renal allograft.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
2014-12-08 | Journal article
DOI: 10.1111/ajt.12964
PMID: 25488654
Source: Self-asserted source
Nicolas Poirier

Advantages of Papio anubis for preclinical testing of immunotoxicity of candidate therapeutic antagonist antibodies targeting CD28.

mAbs
2014-03-05 | Journal article
DOI: 10.4161/mabs.28375
PMID: 24598534
PMC: PMC4011914
Source: Self-asserted source
Nicolas Poirier

Targeting CD28, CTLA-4 and PD-L1 costimulation differentially controls immune synapses and function of human regulatory and conventional T-cells.

PloS one
2013-12-23 | Journal article
DOI: 10.1371/journal.pone.0083139
PMID: 24376655
PMC: PMC3871694
Source: Self-asserted source
Nicolas Poirier

Antagonist properties of monoclonal antibodies targeting human CD28: role of valency and the heavy-chain constant domain.

mAbs
2012-12-05 | Journal article
DOI: 10.4161/mabs.22697
PMID: 23221503
PMC: PMC3564885
Source: Self-asserted source
Nicolas Poirier

Gene transfer of human CD40Ig does not prevent rejection in a non-human primate kidney allotransplantation model.

Transplant immunology
2012-10-23 | Journal article
DOI: 10.1016/j.trim.2012.10.004
PMID: 23098770
Source: Self-asserted source
Nicolas Poirier

Preclinical efficacy and immunological safety of FR104, an antagonist anti-CD28 monovalent Fab' antibody.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
2012-07-03 | Journal article
DOI: 10.1111/j.1600-6143.2012.04164.x
PMID: 22759318
Source: Self-asserted source
Nicolas Poirier

CD28-specific immunomodulating antibodies: what can be learned from experimental models?

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
2012-04-04 | Journal article
DOI: 10.1111/j.1600-6143.2012.04032.x
PMID: 22471377
Source: Self-asserted source
Nicolas Poirier

Control of transplant tolerance and intragraft regulatory T cell localization by myeloid-derived suppressor cells and CCL5.

Journal of immunology (Baltimore, Md. : 1950)
2012-03-26 | Journal article
DOI: 10.4049/jimmunol.1101512
PMID: 22450806
Source: Self-asserted source
Nicolas Poirier

Transplant tolerance is associated with reduced expression of cystathionine-γ-lyase that controls IL-12 production by dendritic cells and TH-1 immune responses.

Blood
2012-01-19 | Journal article
DOI: 10.1182/blood-2011-04-350546
PMID: 22262763
Source: Self-asserted source
Nicolas Poirier

Xenotransplantation of galactosyl-transferase knockout, CD55, CD59, CD39, and fucosyl-transferase transgenic pig kidneys into baboons.

Transplantation proceedings
2011-11-01 | Journal article
DOI: 10.1016/j.transproceed.2011.09.024
PMID: 22099813
Source: Self-asserted source
Nicolas Poirier

Antibody-mediated depletion of lymphocyte-activation gene-3 (LAG-3(+) )-activated T lymphocytes prevents delayed-type hypersensitivity in non-human primates.

Clinical and experimental immunology
2011-02-24 | Journal article
DOI: 10.1111/j.1365-2249.2011.04329.x
PMID: 21352204
Source: Self-asserted source
Nicolas Poirier

A more selective costimulatory blockade of the CD28-B7 pathway.

Transplant international : official journal of the European Society for Organ Transplantation
2010-10-21 | Journal article
DOI: 10.1111/j.1432-2277.2010.01176.x
PMID: 20964725
Source: Self-asserted source
Nicolas Poirier

Alternatives to calcineurin inhibition in renal transplantation: belatacept, the first co-stimulation blocker.

Immunotherapy
2010-09-01 | Journal article
DOI: 10.2217/imt.10.57
PMID: 20874646
Source: Self-asserted source
Nicolas Poirier

Recombinant human C1-inhibitor prevents acute antibody-mediated rejection in alloimmunized baboons.

Kidney international
2010-03-24 | Journal article
DOI: 10.1038/ki.2010.75
PMID: 20336054
Source: Self-asserted source
Nicolas Poirier

Inducing CTLA-4-dependent immune regulation by selective CD28 blockade promotes regulatory T cells in organ transplantation.

Science translational medicine
2010-02-01 | Journal article
DOI: 10.1126/scitranslmed.3000116
PMID: 20371478
PMC: PMC2860737
Source: Self-asserted source
Nicolas Poirier

Depleting T-cell subpopulations in organ transplantation.

Transplant international : official journal of the European Society for Organ Transplantation
2008-10-30 | Journal article
DOI: 10.1111/j.1432-2277.2008.00788.x
PMID: 18980625
Source: Self-asserted source
Nicolas Poirier

Myeloid-derived suppressor cells accumulate in kidney allograft tolerance and specifically suppress effector T cell expansion.

Journal of immunology (Baltimore, Md. : 1950)
2008-06-01 | Journal article
DOI: 10.4049/jimmunol.180.12.7898
PMID: 18523253
Source: Self-asserted source
Nicolas Poirier

Recombinant human C1-inhibitor inhibits cytotoxicity induced by allo- and xenoantibodies.

Transplantation proceedings
2008-03-01 | Journal article
DOI: 10.1016/j.transproceed.2008.01.045
PMID: 18374134
Source: Self-asserted source
Nicolas Poirier

Acute humoral rejection of renal transplants in alloimmunized pigs.

The Journal of surgical research
2007-03-13 | Journal article
DOI: 10.1016/j.jss.2006.08.034
PMID: 17360000
Source: Self-asserted source
Nicolas Poirier

Peer review (1 review for 1 publication/grant)

Review activity for Nature communications (1)
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