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Employment (2)

Medizinische Hochschule Hannover: Hannover, Niedersachsen, DE

2022-03-01 to present | Junior group leader (Klinik für Gastroenterologie, Hepatologie und Endokrinologie)
Employment
Source: Self-asserted source
Doan Duy Hai Tran

Medizinische Hochschule Hannover: Hannover, Niedersachsen, DE

2014-01-01 to 2019-12-31 | Postdoc/Dr. (Institute for Cell Biochemistry)
Employment
Source: Self-asserted source
Doan Duy Hai Tran

Education and qualifications (2)

Medizinische Hochschule Hannover: Hannover, Niedersachsen, DE

2021-12-01 to 2021-12-01 | Habilitation (PD)
Education
Source: Self-asserted source
Doan Duy Hai Tran

Leibniz Universität Hannover: Hannover, Niedersachsen, DE

2004-10-01 to 2009-10-30 | Diplom (Biochemistry)
Qualification
Source: Self-asserted source
Doan Duy Hai Tran

Professional activities (3)

Frontiers in Cell and Developmental Biology: Lausanne, CH

2021-09-01 to present | Review Editor
Invited position
Source: Self-asserted source
Doan Duy Hai Tran

The (German) Society for Biochemistry and Molecular Biology: Bonn, DE

2013-01-01 to present
Membership
Source: Self-asserted source
Doan Duy Hai Tran

Signal Transduction Society: Weimar, DE

2012-01-01 to present
Service
Source: Self-asserted source
Doan Duy Hai Tran

Funding (4)

Identification and characterization of a potential Biomarker and Modulator for HCC development derived from cancer type-specific long noncoding (Lnc) RNAs

2019-03 to 2023-03 | Grant
Deutsche Forschungsgemeinschaft (Bonn, DE)
Source: Self-asserted source
Doan Duy Hai Tran

Application of Third Generation Sequencing (Nanopore Sequencing Technology): Identification of regulatory lncRNAs involved in sorafenib resistance

2018-07 to 2021-07 | Grant
Young Faculty Program of Hannover Medical School (Hannover, DE)
Source: Self-asserted source
Doan Duy Hai Tran

Identification of novel tumorsuppressor genes and epigenetic markers by profiling genome-wide methylation using Nanopore Sequencing Technology

2017-01 to 2018-01 | Grant
Lower Saxony Cancer Foundation (Hannover, DE)
Source: Self-asserted source
Doan Duy Hai Tran

Characterization of potential tumor suppressor THOC7, a member of mRNA export complex

2015-01 to 2016-01 | Grant
Hochschulinterne Leistungsförderung (HilF) (Hannover, DE)
Source: Self-asserted source
Doan Duy Hai Tran

Works (20)

Mapping alternative polyadenylation in human cells using direct RNA sequencing technology

STAR Protocols
2023-09 | Journal article
DOI: 10.1016/j.xpro.2023.102420
Contributors: Mareike Polenkowski; Aldrige Bernardus Allister; Sebastian Burbano de Lara; Madleen Soltau; Gajanan Kendre; Doan Duy Hai Tran
Source: check_circle
Crossref

THOC5 complexes with DDX5, DDX17, and CDK12 to regulate R loop structures and transcription elongation rate

iScience
2023-01 | Journal article | Author
DOI: 10.1016/j.isci.2022.105784
Part of ISSN: 2589-0042
Contributors: Mareike Polenkowski; Aldrige Bernardus Allister; Sebastian Burbano de Lara; Andrew Pierce; Bethany Geary; Omar El Bounkari; Lutz Wiehlmann; Andrea Hoffmann; Anthony D. Whetton; Teruko Tamura et al.
Source: Self-asserted source
Doan Duy Hai Tran
grade
Preferred source (of 2)‎

Identification of Novel Micropeptides Derived from Hepatocellular Carcinoma-Specific Long Noncoding RNA

International Journal of Molecular Sciences
2021-12-21 | Journal article
DOI: 10.3390/ijms23010058
Contributors: Mareike Polenkowski; Sebastian Burbano de Lara; Aldrige Allister; Thi Nguyen; Teruko Tamura; Doan Tran
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Genome-Wide Methylation Mapping Using Nanopore Sequencing Technology Identifies Novel Tumor Suppressor Genes in Hepatocellular Carcinoma

International Journal of Molecular Sciences
2021-04 | Journal article | Author
DOI: 10.3390/ijms22083937
Contributors: Colin F Davenport; Tobias Scheithauer; Alessia Dunst; Frauke Sophie Bahr; Marie Dorda; Lutz Wiehlmann; Doan Duy Hai Tran
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

C20orf204, a hepatocellular carcinoma-specific protein interacts with nucleolin and promotes cell proliferation.

Oncogenesis
2021-03-17 | Journal article
DOI: 10.1038/s41389-021-00320-3
PMID: 33731669
PMC: PMC7969625
Source: Self-asserted source
Doan Duy Hai Tran

Myc/Max dependent intronic long antisense noncoding RNA, EVA1A-AS, suppresses the expression of Myc/Max dependent anti-proliferating gene EVA1A in a U2 dependent manner.

Scientific reports
2019-11-21 | Journal article
DOI: 10.1038/s41598-019-53944-2
PMID: 31754186
PMC: PMC6872820
Source: Self-asserted source
Doan Duy Hai Tran

Colony-stimulating factor-1 receptor provides a growth advantage in epithelial cancer cell line A431 in the presence of epidermal growth factor receptor inhibitor gefitinib.

Cellular signalling
2018-07-31 | Journal article
DOI: 10.1016/j.cellsig.2018.07.014
PMID: 30075184
Source: Self-asserted source
Doan Duy Hai Tran

Myc target gene, long intergenic noncoding RNA, Linc00176 in hepatocellular carcinoma regulates cell cycle and cell survival by titrating tumor suppressor microRNAs.

Oncogene
2017-09-04 | Journal article
DOI: 10.1038/onc.2017.312
PMID: 28869604
Source: Self-asserted source
Doan Duy Hai Tran

Treatment with MAPKAP2 (MK2) inhibitor and DNA methylation inhibitor, 5-aza dC, synergistically triggers apoptosis in hepatocellular carcinoma (HCC) via tristetraprolin (TTP).

Cellular signalling
2016-09-13 | Journal article
DOI: 10.1016/j.cellsig.2016.09.002
PMID: 27619201
Source: Self-asserted source
Doan Duy Hai Tran

Extracellular-signal regulated kinase (Erk1/2), mitogen-activated protein kinase-activated protein kinase 2 (MK2) and tristetraprolin (TTP) comprehensively regulate injury-induced immediate early gene (IEG) response in in vitro liver organ culture.

Cellular signalling
2016-02-11 | Journal article
DOI: 10.1016/j.cellsig.2016.02.007
PMID: 26876787
Source: Self-asserted source
Doan Duy Hai Tran

mRNA export protein THOC5 as a tool for identification of target genes for cancer therapy.

Cancer letters
2016-01-28 | Journal article
DOI: 10.1016/j.canlet.2016.01.045
PMID: 26828015
Source: Self-asserted source
Doan Duy Hai Tran

Depletion of three combined THOC5 mRNA export protein target genes synergistically induces human hepatocellular carcinoma cell death.

Oncogene
2015-11-09 | Journal article
DOI: 10.1038/onc.2015.433
PMID: 26549021
Source: Self-asserted source
Doan Duy Hai Tran

Murine precision-cut liver slices (PCLS): a new tool for studying tumor microenvironments and cell signaling ex vivo.

Cell communication and signaling : CCS
2014-11-07 | Journal article
DOI: 10.1186/s12964-014-0073-7
PMID: 25376987
PMC: PMC4226874
Source: Self-asserted source
Doan Duy Hai Tran

THOC5 controls 3'end-processing of immediate early genes via interaction with polyadenylation specific factor 100 (CPSF100).

Nucleic acids research
2014-10-01 | Journal article
DOI: 10.1093/nar/gku911
PMID: 25274738
PMC: PMC4231767
Source: Self-asserted source
Doan Duy Hai Tran

THOC5, a member of the mRNA export complex: a novel link between mRNA export machinery and signal transduction pathways in cell proliferation and differentiation.

Cell communication and signaling : CCS
2014-01-10 | Journal article
DOI: 10.1186/1478-811x-12-3
PMID: 24410813
PMC: PMC3899923
Source: Self-asserted source
Doan Duy Hai Tran

THOC5, a member of the mRNA export complex, contributes to processing of a subset of wingless/integrated (Wnt) target mRNAs and integrity of the gut epithelial barrier.

BMC cell biology
2013-11-22 | Journal article
DOI: 10.1186/1471-2121-14-51
PMID: 24267292
PMC: PMC4222586
Source: Self-asserted source
Doan Duy Hai Tran

Transcriptional regulation of immediate-early gene response by THOC5, a member of mRNA export complex, contributes to the M-CSF-induced macrophage differentiation.

Cell death & disease
2013-10-24 | Journal article
DOI: 10.1038/cddis.2013.409
PMID: 24157873
PMC: PMC3920956
Source: Self-asserted source
Doan Duy Hai Tran

A pathway from leukemogenic oncogenes and stem cell chemokines to RNA processing via THOC5.

Leukemia
2012-10-03 | Journal article
DOI: 10.1038/leu.2012.283
PMID: 23032722
Source: Self-asserted source
Doan Duy Hai Tran

An ataxia-telangiectasia-mutated (ATM) kinase mediated response to DNA damage down-regulates the mRNA-binding potential of THOC5.

RNA (New York, N.Y.)
2011-09-21 | Journal article
DOI: 10.1261/rna.2820911
PMID: 21937706
PMC: PMC3198589
Source: Self-asserted source
Doan Duy Hai Tran

Identification of mRNAs that are spliced but not exported to the cytoplasm in the absence of THOC5 in mouse embryo fibroblasts.

RNA (New York, N.Y.)
2011-04-27 | Journal article
DOI: 10.1261/rna.2607011
PMID: 21525145
PMC: PMC3096037
Source: Self-asserted source
Doan Duy Hai Tran

Peer review (5 reviews for 3 publications/grants)

Review activity for Cell death and disease. (1)
Review activity for Cellular & Molecular Biology Letters. (1)
Review activity for Molecular cancer (3)
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