Personal information

Taiwan

Activities

Employment (5)

Taipei Medical University: Taipei, TW

2020-08 to present | Professor (Graduate Institute of Translational Medicine, College of Medical Science and Technology)
Employment
Source: Self-asserted source
Hao-Ching Wang

Taipei Medical University: Taipei, TW

2017-02 to 2021-07 | Associate professor (Graduate Institute of Translational Medicine, College of Medical Science and Technology)
Employment
Source: Self-asserted source
Hao-Ching Wang

Taipei Medical University: Taipei, TW

2013-08 to 2017-01 | Assistant professor (Graduate Institute of Translational Medicine, College of Medical Science and Technology)
Employment
Source: Self-asserted source
Hao-Ching Wang

Academia Sinica: Taipei, TW

2011-01 to 2013-07 | Distinguished Postdoctoral Scholar (Institute of Biological Chemistry)
Employment
Source: Self-asserted source
Hao-Ching Wang

Academia Sinica: Taipei, TW

2009-09 to 2010-12 | Postdoctoral Fellow (Institute of Biological Chemistry)
Employment
Source: Self-asserted source
Hao-Ching Wang

Education and qualifications (1)

Institute of Biochemical Sciences: Taipei, TW

2003 to 2008 | Ph. D. (National Taiwan University)
Education
Source: Self-asserted source
Hao-Ching Wang

Funding (7)

Functional Study of Phytoplasma Phyl1 Interacting Proteins Using Structural and Proteomic Approaches – Stage 2 Study

2021-08 to 2024-07 | Grant
National Science and Technology Council (Taipei, TW)
Source: Self-asserted source
Hao-Ching Wang

Exploring the Activation Mechanism and Neutralization Strategy of the Ahpnd-Causing Toxins Piravp and Pirbvp

2020-08 to 2023-07 | Grant
National Science and Technology Council (Taipei, TW)
Source: Self-asserted source
Hao-Ching Wang

Functional Study of Phytoplasma Phyl1 Interacting Proteins Using Structural and Proteomic Approaches

2020-08 to 2021-07 | Grant
National Science and Technology Council (Taipei, TW)
Source: Self-asserted source
Hao-Ching Wang

Investigation of the Cytotoxic Mechanism of Photorhabdus Luminescens Pirapl and Pirbpl Toxins by Using Structural and Proteomic Approaches

2018-08 to 2019-07 | Grant
National Science and Technology Council (Taipei, TW)
Source: Self-asserted source
Hao-Ching Wang

Exploring the potential applications of DNA mimic protein SAUGI in viral diseases and MRSA by structure-based study

2017-08 to 2018-07 | Grant
Ministry of Science and Technology, Taiwan (Taipei, TW)
GRANT_NUMBER:

106-2311-B-038-002

Source: Self-asserted source
Hao-Ching Wang

Uncovering the specific interactions between DNA mimic proteins and their target DNA binding proteins by structure-based studies

2014-08 to 2017-07 | Grant
Ministry of Science and Technology, Taiwan (Taipei, TW)
GRANT_NUMBER:

103-2311-B-038-005-MY3

Source: Self-asserted source
Hao-Ching Wang

Potential application of the Staphylococcus aureus DNA mimic protein SAUGI in combating human viral disease

2013-10 to 2014-09 | Grant
Ministry of Science and Technology, Taiwan (Taipei, TW)
GRANT_NUMBER:

102-2311-B-038-003

Source: Self-asserted source
Hao-Ching Wang

Works (44)

Ribonuclease 1 Induces T‐Cell Dysfunction and Impairs CD8+ T‐Cell Cytotoxicity to Benefit Tumor Growth through Hijacking STAT1

Advanced Science
2025-02-11 | Journal article
Contributors: Wen‐Hao Yang; Bao‐Yue Huang; Hsing‐Yu Rao; Peng Ye; Bi Chen; Hao‐Ching Wang; Chih‐Hung Chung; Heng‐Hsiung Wu; Hung‐Rong Yen; Shao‐Chun Wang et al.
Source: check_circle
Crossref

Structural insights into the molecular mechanism of phytoplasma immunodominant membrane protein

IUCrJ
2024-05-01 | Journal article
Contributors: Chang-Yi Liu; Han-Pin Cheng; Chan-Pin Lin; Yi-Ting Liao; Tzu-Ping Ko; Shin-Jen Lin; Shih-Shun Lin; Hao-Ching Wang
Source: check_circle
Crossref

Structural and functional analyses of viral H2 protein of the vaccinia virus entry fusion complex

Journal of Virology
2023-12-21 | Journal article
Contributors: Chi-Fei Kao; Chang-Yi Liu; Chia-Lin Hsieh; Kathleen Joyce D. Carillo; Der-Lii M. Tzou; Hao-Ching Wang; Wen Chang; Derek Walsh
Source: check_circle
Crossref

A bacterial binary toxin system that kills both insects and aquatic crustaceans: Photorhabdus insect-related toxins A and B

PLOS Pathogens
2023-05-04 | Journal article
Contributors: Hao-Ching Wang; Christoph Dehio; Shin-Jen Lin; Han-Ching Wang; Ramya Kumar; Phuoc Thien Le; Jiann-Horng Leu
Source: check_circle
Crossref

Multiple Nucleocapsid Structural Forms of Shrimp White Spot Syndrome Virus Suggests a Novel Viral Morphogenetic Pathway

International Journal of Molecular Sciences
2023-04-19 | Journal article
Contributors: Hui-Ju Huang; Sen-Lin Tang; Yuan-Chih Chang; Hao-Ching Wang; Tze Hann Ng; Rees F. Garmann; Yu-Wen Chen; Jiun-Yan Huang; Ramya Kumar; Sheng-Hsiung Chang et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

An undefined cystatin CsCPI1 from tea plant Camellia sinensis harbors antithrombotic activity

Biomedicine & Pharmacotherapy
2023-03 | Journal article
Part of ISSN: 0753-3322
Contributors: Mingqian Fang; Jong-Ho Cha; Hao-Ching Wang; Peng Ye; Bi Chen; Mengrou Chen; Wen-Hao Yang; Xiuwen Yan
Source: Self-asserted source
Hao-Ching Wang

Novel Algorithm for Improved Protein Classification Using Graph Similarity

IEEE/ACM Transactions on Computational Biology and Bioinformatics
2022 | Journal article
Part of ISSN: 1545-5963
Part of ISSN: 1557-9964
Part of ISSN: 2374-0043
Contributors: Hsin-Hung Chou; Ching-Tien Hsu; Chin-Wei Hsu; Kai-Hsun Yao; Hao-Ching Wang; Sun-Yuan Hsieh
Source: Self-asserted source
Hao-Ching Wang
grade
Preferred source (of 2)‎

Expression of the AHPND Toxins PirAvp and PirBvp Is Regulated by Components of the Vibrio parahaemolyticus Quorum Sensing (QS) System

International Journal of Molecular Sciences
2022-03-07 | Journal article
Contributors: Shin-Jen Lin; Jiun-Yan Huang; Phuoc-Thien Le; Chung-Te Lee; Che-Chang Chang; Yi-Yuan Yang; Emily Chia-Yu Su; Chu-Fang Lo; Hao-Ching Wang
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Investigating the Viral Suppressor HC-Pro Inhibiting Small RNA Methylation through Functional Comparison of HEN1 in Angiosperm and Bryophyte

Viruses
2021-09-15 | Journal article
Contributors: Neda Sanobar; Pin-Chun Lin; Zhao-Jun Pan; Ru-Ying Fang; Veny Tjita; Fang-Fang Chen; Hao-Ching Wang; Huang-Lung Tsai; Shu-Hsing Wu; Tang-Long Shen et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Identification and characterization of l-amino acid oxidase 2 gene in orange-spotted grouper (Epinephelus coioides)

Developmental & Comparative Immunology
2021-07 | Journal article
Part of ISSN: 0145-305X
Contributors: Jiann-Horng Leu; Chi-Hang Tsai; Chia-Hsun Yang; Hsin-Yiu Chou; Hao-Ching Wang
Source: Self-asserted source
Hao-Ching Wang

Synthesis and biological evaluation of phenothiazine derivative-containing hydroxamic acids as potent class II histone deacetylase inhibitors

European Journal of Medicinal Chemistry
2021-07 | Journal article
Part of ISSN: 0223-5234
Contributors: Kai-Cheng Hsu; Jung-Chun Chu; Hui-Ju Tseng; Chia-I Liu; Hao-Ching Wang; Tony Eight Lin; Hong-Sheng Lee; Ling-Wei Hsin; Andrew H.-J. Wang; Chien-Huang Lin et al.
Source: Self-asserted source
Hao-Ching Wang

A shrimp glycosylase protein, PmENGase, interacts with WSSV envelope protein VP41B and is involved in WSSV pathogenesis

Developmental & Comparative Immunology
2020-07 | Journal article
Part of ISSN: 0145-305X
Contributors: Jiun-Yan Huang; Hao-Ching Wang; Yu-Chun Chen; Po-Sue Wang; Shin-Jen Lin; Yun-Shiang Chang; Kuan-Fu Liu; Chu-Fang Lo
Source: Self-asserted source
Hao-Ching Wang

A Review of the Functional Annotations of Important Genes in the AHPND-Causing pVA1 Plasmid

Microorganisms
2020-07-03 | Journal article
Contributors: Hao-Ching Wang; Shin-Jen Lin; Arpita Mohapatra; Ramya Kumar; Han-Ching Wang
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Structural insights into the interaction between phytoplasmal effector causing phyllody 1 and MADS transcription factors

The Plant Journal
2019-11 | Journal article
Contributors: Yi‐Ting Liao; Shih‐Shun Lin; Shin‐Jen Lin; Wan‐Ting Sun; Bing‐Nan Shen; Han‐Pin Cheng; Chan‐Pin Lin; Tzu‐Ping Ko; Yi‐Fan Chen; Hao‐Ching Wang
Source: check_circle
Crossref

Vaccinia viral A26 protein is a fusion suppressor of mature virus and triggers membrane fusion through conformational change at low pH

PLOS Pathogens
2019-06-20 | Journal article
Contributors: Hung-Wei Chang; Richard C. Condit; Cheng-Han Yang; Yu-Chun Luo; Bo-Gang Su; Huei-Yin Cheng; Shu-Yun Tung; Kathleen Joyce D. Carillo; Yi-Ting Liao; Der-Lii M. Tzou et al.
Source: check_circle
Crossref

New paradigm of functional regulation by DNA mimic proteins: Recent updates

IUBMB Life
2019-05 | Journal article
Part of ISSN: 1521-6543
Part of ISSN: 1521-6551
Contributors: Hao‐Ching Wang; Chia‐Cheng Chou; Kai‐Cheng Hsu; Chi‐Hua Lee; Andrew H.-J. Wang
Source: Self-asserted source
Hao-Ching Wang

Structural Insights to the Heterotetrameric Interaction between the Vibrio parahaemolyticus PirAvp and PirBvp Toxins and Activation of the Cry-Like Pore-Forming Domain

Toxins
2019-04-22 | Journal article
Contributors: Shin-Jen Lin; Yi-Fan Chen; Kai-Cheng Hsu; Yun-Ling Chen; Tzu-Ping Ko; Chu-Fang Lo; Han-Ching Wang; Hao-Ching Wang
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Gene-to-Gene Network Analysis of the Mediation of Plant Innate Immunity by the Eliciting Plant Response-Like 1 (Epl1) Elicitor of <i>Trichoderma formosa</i>

Molecular Plant-Microbe Interactions®
2018-07 | Journal article
Part of ISSN: 0894-0282
Part of ISSN: 1943-7706
Contributors: Chi-Hua Cheng; Bing-Nan Shen; Qian-Wen Shang; Li-Yu Daisy Liu; Kou-Cheng Peng; Yan-Huey Chen; Fang-Fang Chen; Sin-Fen Hu; Yu-Tai Wang; Hao-Ching Wang et al.
Source: Self-asserted source
Hao-Ching Wang

Dual Inhibition of PIK3C3 and FGFR as a New Therapeutic Approach to Treat Bladder Cancer

Clinical Cancer Research
2017 | Journal article
Part of ISSN: 1078-0432
Contributors: Chun-Han Chen; C. Changou; Tsung-Han Hsieh; Yu-Ching Lee; Cheng-Ying Chu; Kai-Cheng Hsu; Hao-Ching Wang; Yu-Chen Lin; Yan-Ni Lo; Yun-Ru Liu et al.
Source: Self-asserted source
Hao-Ching Wang via Crossref Metadata Search

The monomeric form of Neisseria DNA mimic protein DMP19 prevents DNA from binding to the histone-like HU protein

PLOS ONE
2017-12-08 | Journal article
Contributors: Ming-Fen Huang; Akira Ishihama; Shin-Jen Lin; Tzu-Ping Ko; Yi-Ting Liao; Kai-Cheng Hsu; Hao-Ching Wang
Source: check_circle
Crossref

Structural Insights into the Cytotoxic Mechanism of Vibrio parahaemolyticus PirAvp and PirBvp Toxins

Marine Drugs
2017-12-01 | Journal article
Contributors: Shin-Jen Lin; Kai-Cheng Hsu; Hao-Ching Wang
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Using structural-based protein engineering to modulate the differential inhibition effects of SAUGI on human and HSV uracil DNA glycosylase

Nucleic Acids Research
2016 | Journal article
EID:

2-s2.0-84970007062

Contributors: Wang, H.-C.; Ho, C.-H.; Chou, C.-C.; Ko, T.-P.; Huang, M.-F.; Hsu, K.-C.; Wang, A.H.-J.
Source: Self-asserted source
Hao-Ching Wang via Scopus - Elsevier

A novel detection platform for shrimp white spot syndrome virus using an ICP11-dependent immunomagnetic reduction (IMR) assay

PLoS ONE
2015 | Journal article
EID:

2-s2.0-84946594015

Contributors: Liu, B.-H.; Lin, Y.-C.; Ho, C.-S.; Yang, C.-C.; Chang, Y.-T.; Chang, J.-F.; Li, C.-Y.; Cheng, C.-S.; Huang, J.-Y.; Lee, Y.-F. et al.
Source: Self-asserted source
Hao-Ching Wang via Scopus - Elsevier

Erratum: The opportunistic marine pathogen Vibrio parahaemolyticus becomes virulent by acquiring a plasmid that expresses a deadly toxin (Proceedings of the National Academy of Sciences of the United States of America (2015) 112 (10798-10803))

Proceedings of the National Academy of Sciences of the United States of America
2015 | Journal article
EID:

2-s2.0-84942693300

Contributors: Lee, C.-T.; Chen, I.-T.; Yang, Y.-T.; Ko, T.-P.; Huang, Y.-T.; Huang, J.-Y.; Huang, M.-F.; Lin, S.-J.; Chen, C.-Y.; Lin, S.-S. et al.
Source: Self-asserted source
Hao-Ching Wang via Scopus - Elsevier

The opportunistic marine pathogen Vibrio parahaemolyticus becomes virulent by acquiring a plasmid that expresses a deadly toxin

Proceedings of the National Academy of Sciences of the United States of America
2015 | Journal article
EID:

2-s2.0-84940493708

Contributors: Lee, C.-T.; Chen, I.-T.; Yang, Y.-T.; Ko, T.-P.; Huang, Y.-T.; Huang, J.-Y.; Huang, M.-F.; Lin, S.-J.; Chen, C.-Y.; Lin, S.-S. et al.
Source: Self-asserted source
Hao-Ching Wang via Scopus - Elsevier

White spot syndrome virus protein kinase 1 defeats the host cell's iron-withholding defense mechanism by interacting with host ferritin

Journal of Virology
2015 | Journal article
EID:

2-s2.0-84920771787

Contributors: Lin, S.-J.; Lee, D.-Y.; Wang, H.-C.; Kang, S.-T.; Hwang, P.-P.; Kou, G.-H.; Huang, M.-F.; Chang, G.-D.; Loa, C.-F.
Source: Self-asserted source
Hao-Ching Wang via Scopus - Elsevier

Crowning proteins: Modulating the protein surface properties using crown ethers

Angewandte Chemie - International Edition
2014 | Journal article
EID:

2-s2.0-84915748746

Contributors: Lee, C.-C.; Maestre-Reyna, M.; Hsu, K.-C.; Wang, H.-C.; Liu, C.-I.; Jeng, W.-Y.; Lin, L.-L.; Wood, R.; Chou, C.-C.; Yang, J.-M. et al.
Source: Self-asserted source
Hao-Ching Wang via Scopus - Elsevier

DNA mimic proteins: Functions, structures, and bioinformatic analysis

Biochemistry
2014 | Journal article
EID:

2-s2.0-84900559770

Contributors: Wang, H.-C.; Ho, C.-H.; Hsu, K.-C.; Yang, J.-M.; Wang, A.H.-J.
Source: Self-asserted source
Hao-Ching Wang via Scopus - Elsevier

Staphylococcus aureus protein SAUGI acts as a uracil-DNA glycosylase inhibitor

Nucleic Acids Research
2014 | Journal article
EID:

2-s2.0-84893236435

Contributors: Wang, H.-C.; Hsu, K.-C.; Yang, J.-M.; Wu, M.-L.; Ko, T.-P.; Lin, S.-R.; Wang, A.H.-J.
Source: Self-asserted source
Hao-Ching Wang via Scopus - Elsevier

The T4 phage DNA mimic protein arn inhibits the DNA binding activity of the bacterial histone-like protein H-NS

Journal of Biological Chemistry
2014 | Journal article
EID:

2-s2.0-84907457043

Contributors: Ho, C.-H.; Wang, H.-C.; Ko, T.-P.; Chang, Y.-C.; Wang, A.H.-J.
Source: Self-asserted source
Hao-Ching Wang via Scopus - Elsevier

Neisseria conserved hypothetical protein DMP12 is a DNA mimic that binds to histone-like HU protein

Nucleic Acids Research
2013 | Journal article
EID:

2-s2.0-84877304449

Contributors: Wang, H.-C.; Wu, M.-L.; Ko, T.-P.; Wang, A.H.-J.
Source: Self-asserted source
Hao-Ching Wang via Scopus - Elsevier

Neisseria conserved protein DMP19 is a DNA mimic protein that prevents DNA binding to a hypothetical nitrogen-response transcription factor

Nucleic Acids Research
2012 | Journal article
EID:

2-s2.0-84863222948

Contributors: Wang, H.-C.; Ko, T.-P.; Wu, M.-L.; Ku, S.-C.; Wu, H.-J.; Wang, A.H.-J.
Source: Self-asserted source
Hao-Ching Wang via Scopus - Elsevier

Penaeus monodon thioredoxin restores the DNA binding activity of oxidized white spot syndrome virus IE1

Antioxidants and Redox Signaling
2012 | Journal article
EID:

2-s2.0-84863919224

Contributors: Huang, J.-Y.; Liu, W.-J.; Wang, H.-C.; Lee, D.-Y.; Leu, J.-H.; Wang, H.-C.; Tsai, M.-H.; Kang, S.-T.; Chen, I.-T.; Kou, G.-H. et al.
Source: Self-asserted source
Hao-Ching Wang via Scopus - Elsevier

Proteomic analysis of differentially expressed proteins in the lymphoid organ of Vibrio harveyi-infected Penaeus monodon

Molecular Biology Reports
2012 | Journal article
EID:

2-s2.0-84863739983

Contributors: Chaikeeratisak, V.; Somboonwiwat, K.; Wang, H.-C.; Lo, C.F.; Tassanakajon, A.
Source: Self-asserted source
Hao-Ching Wang via Scopus - Elsevier

Substrate binding of a GH5 endoglucanase from the ruminal fungus Piromyces rhizinflata

Acta Crystallographica Section F: Structural Biology and Crystallization Communications
2011 | Journal article
EID:

2-s2.0-80955135673

Contributors: Tseng, C.-W.; Ko, T.-P.; Guo, R.-T.; Huang, J.-W.; Wang, H.-C.; Huang, C.-H.; Cheng, Y.-S.; Wang, A.H.-J.; Liu, J.-R.
Source: Self-asserted source
Hao-Ching Wang via Scopus - Elsevier

The role of aldehyde dehydrogenase and Hsp70 in suppression of white spot syndrome virus replication at high temperature

Journal of Virology
2011 | Journal article
EID:

2-s2.0-79952587378

Contributors: Lin, Y.-R.; Hung, H.-C.; Leu, J.-H.; Wang, H.-C.; Kou, G.-H.; Lo, C.-F.
Source: Self-asserted source
Hao-Ching Wang via Scopus - Elsevier

Proteomic analysis of differentially expressed proteins in Penaeus monodon hemocytes after Vibrio harveyi infection

Proteome Science
2010 | Journal article
EID:

2-s2.0-77954413903

Contributors: Somboonwiwat, K.; Chaikeeratisak, V.; Wang, H.-C.; Fang Lo, C.; Tassanakajon, A.
Source: Self-asserted source
Hao-Ching Wang via Scopus - Elsevier

Penaeus monodon caspase is targeted by a white spot syndrome virus anti-apoptosis protein

Developmental and Comparative Immunology
2008 | Journal article
EID:

2-s2.0-38649105206

Contributors: Leu, J.-H.; Wang, H.-C.; Kou, G.-H.; Lo, C.-F.
Source: Self-asserted source
Hao-Ching Wang via Scopus - Elsevier

Transactivation, dimerization, and DNA-binding activity of white spot syndrome virus immediate-early protein IE1

Journal of Virology
2008 | Journal article
EID:

2-s2.0-55549111874

Contributors: Liu, W.-J.; Chang, Y.-S.; Wang, H.-C.; Leu, J.-H.; Kou, G.-H.; Lo, C.-F.
Source: Self-asserted source
Hao-Ching Wang via Scopus - Elsevier

White spot syndrome virus protein ICP11: A histone-binding DNA mimic that disrupts nucleosome assembly

Proceedings of the National Academy of Sciences of the United States of America
2008 | Journal article
EID:

2-s2.0-58549094285

Contributors: Wang, H.-C.; Wang, H.-C.; Ko, T.-P.; Lee, Y.-M.; Leu, J.-H.; Ho, C.-H.; Huang, W.-P.; Lo, C.-F.; Wang, A.H.-J.
Source: Self-asserted source
Hao-Ching Wang via Scopus - Elsevier

Analysis of differently expressed proteins and transcripts in gills of Penaeus vannamei after yellow head virus infection

Proteomics
2007 | Journal article
EID:

2-s2.0-35648986063

Contributors: Rattanarojpong, T.; Wang, H.-C.; Lo, C.-F.; Flegel, T.W.
Source: Self-asserted source
Hao-Ching Wang via Scopus - Elsevier

Identification of icp11, the most highly expressed gene of shrimp white spot syndrome virus (WSSV)

Diseases of Aquatic Organisms
2007 | Journal article
EID:

2-s2.0-34247510197

Contributors: Wang, H.-C.; Wang, H.-C.; Kou, G.-H.; Lo, C.-F.; Huang, W.-P.
Source: Self-asserted source
Hao-Ching Wang via Scopus - Elsevier

Protein expression profiling of the shrimp cellular response to white spot syndrome virus infection

Developmental and Comparative Immunology
2007 | Journal article
EID:

2-s2.0-33947732449

Contributors: Wang, H.-C.; Wang, H.-C.; Leu, J.-H.; Kou, G.-H.; Wang, A.H.-J.; Lo, C.-F.
Source: Self-asserted source
Hao-Ching Wang via Scopus - Elsevier

Identification of icp11, the most highly expressed gene of shrimp white spot syndrome virus (WSSV).

Diseases of aquatic organisms
2007-03 | Journal article
Source: Self-asserted source
Hao-Ching Wang via Europe PubMed Central

Peer review (5 reviews for 2 publications/grants)

Review activity for Aquaculture. (3)
Review activity for Developmental and comparative immunology. (2)