Urmi Bajpai (0000-0003-2441-6089)

Personal information

Biography

Professor,
Department of Biomedical Science,
Acharya Narendra Dev College, University of Delhi, India

My group focuses on bacteriophages and the encoded lytic enzymes as alternatives/adjuncts to antibiotics. We have purified over 200 mycobacteriophages and several mycobacteriophage-derived endolysins as potential therapeutic candidates against Tuberculosis and Non-tuberculous Mycobacterial (NTM) infections. We also work on discovering small-molecule inhibitors as drug candidates that target Mur enzymes in M. tuberculosis.

Activities

Collapse all

Bacteriophages: The natural combatants to fight AMR

Emerging Paradigms for Antibiotic-Resistant Infections: Beyond the Pill

2024 | Book chapter

Contributors: Urmi Bajpai

Urmi Bajpai

https://orcid.org/0000-0003-2441-6089

Personal information

Keywords

Countries

Biography

Activities

Works (31)

Bacteriophages: The natural combatants to fight AMR

Unlocking prophage potential: In silico and experimental analysis of a novel Mycobacterium fortuitum LysinB containing a peptidoglycan-binding domain

Discovery and Characterization of a Novel LysinB from F2 Sub-Cluster Mycobacteriophage RitSun

Mycobacteriophages: Therapeutic Approach for Mycobacterial Infections.

Insights into the genomic features and lifestyle of B1 subcluster mycobacteriophages.

Genome announcement and analysis of five new mycobacteriophages belonging to the F, G, K, and P clusters

Phage-encoded lysins as promising antibacterials against uropathogenic Escherichia coli.

Beyond antibiotics: Phage-encoded lysins against Gram-negative pathogens.

Bacteriophages in the Treatment of Biofilms

Functional characterization of a DNA-dependent AAA ATPase in SimranZ1, an F cluster mycobacteriophage

). Identification of Perturbed Pathways Rendering Susceptibility to Tuberculosis in Type 2 Diabetes Mellitus Patients Using BioNSi Simulation of Integrated Network of Implicated Human Genes

Alternative Treatment of Secondary Bacterial and Fungal Infections Associated with Covid-19

Translational Bioinformatics Methods for Drug Repurposing

Computational identification and characterization of antigenic properties of Rv3899c of Mycobacterium tuberculosis and its interaction with human leukocyte antigen (HLA).

In silico prediction of natural compounds as potential multi-target inhibitors of structural proteins of SARS-CoV-2

Screening of compound library identifies novel inhibitors against the MurA enzyme of Escherichia coli

Design and Synthesis of Various 5′-Deoxy-5′-(4-Substituted-1,2,3-Triazol-1-yl)-Uridine Analogues as Inhibitors of Mycobacterium tuberculosis Mur Ligases

Functional characterization of the endolysins derived from mycobacteriophage PDRPxv

Re-purposing of the FDA-approved drugs to target MurB and MurE enzymes in Mycobacterium tuberculosis

Characterization and genome analysis of B1 sub-cluster mycobacteriophage PDRPxv

Screening of Antitubercular Compound Library Identifies Inhibitors of Mur Enzymes in Mycobacterium tuberculosis

Crystal Structure of UDP-N-acetylglucosamine-enolpyruvate reductase (MurB) from Mycobacterium tuberculosis

Isolation and characterization of bacteriophages from India, with lytic activity against Mycobacterium tuberculosis

Development of a one-pot assay for screening and identification of Mur pathway inhibitors in Mycobacterium tuberculosis

A comparative molecular dynamics study of MurA enzymes from E. coli and M. tuberculosis

Building a repository of potential drug targets in Mycobacterium tuberculosis by crowdsourcing

Functional analysis of TPM domain containing Rv2345 of Mycobacterium tuberculosis identifies its phosphatase activity

Cloning, expression, purification and bioinformatic analysis of 2–methylcitrate synthase from Mycobacterium tuberculosis

Structure based virtual screening to identify inhibitors against MurE Enzyme of Mycobacterium tuberculosis using AutoDock Vina

Clinical significance of 14-3-3 zeta in human esophageal cancer.

Mineralization of (C14) octadecane by Acinetobacter calcoaceticus S19