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Scopus Author ID: 6507416937
ResearcherID: L-2491-2014

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Works (35)

Whole Exome Sequencing in Children With Type 1 Diabetes Before Age 6 Years Reveals Insights Into Disease Heterogeneity

Journal of Diabetes Research
2024-01 | Journal article
DOI: 10.1155/2024/3076895
Contributors: Andreia Fiúza Ribeiro; Ana Laura Fitas; Marcela Oliveira Pires; Paula Matoso; Dário Ligeiro; Daniel Sobral; Carlos Penha-Gonçalves; Jocelyne Demengeot; Íris Caramalho; Catarina Limbert et al.
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The rare DRB1*04:08-DQ8 haplotype is the main HLA class II genetic driver and discriminative factor of Early-onset Type 1 diabetes in the Portuguese population

Frontiers in Immunology
2024-01-03 | Journal article
DOI: 10.3389/fimmu.2023.1299609
Part of ISSN: 1664-3224
Contributors: Iris Caramalho; Paula Matoso; Dário Ligeiro; Tiago Paixão; Daniel Sobral; Ana Laura Fitas; Catarina Limbert; Jocelyne Demengeot; Carlos Penha-Gonçalves
Source: Self-asserted source
Iris Caramalho

Adoptive Transfer and Bone Marrow Chimera Models to Analyze Treg Function and Differentiation

Methods in Molecular Biology
2023 | Book chapter
DOI: 10.1007/978-1-0716-2647-4_2
Part of ISBN: 9781071626467
Part of ISBN: 9781071626474
Part of ISSN: 1064-3745
Part of ISSN: 1940-6029
Contributors: Vital da Silva Domingues; Iris Caramalho; Marie-Louise Bergman; Jocelyne Demengeot
Source: Self-asserted source
Iris Caramalho

The rare DRB1*04-DQ8 haplotype is the main discriminative HLA class II genetic driver of Early-Onset Type 1 Diabetes in the Portuguese population

2023-07-24 | Preprint
DOI: 10.1101/2023.07.23.23293034
Contributors: Iris Caramalho; Paula Matoso; Dário Ligeiro; Tiago Paixão; Daniel Sobral; Ana Laura Fitas; Catarina Limbert; Jocelyne Demengeot; Carlos Penha-Gonçalves
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Crossref

Portuguese Society of Immunology (SPI): Turning 50, inspired by the past, looking into the future

European Journal of Immunology
2023-06-27 | Journal article
DOI: 10.1002/eji.202350570
Part of ISSN: 0014-2980
Part of ISSN: 1521-4141
Contributors: Iris Caramalho; Maria Strecht Almeida; Manuel Vilanova; Carlos Penha‐Gonçalves
Source: Self-asserted source
Iris Caramalho

Influence of the mesenchymal stromal cell source on the hematopoietic supportive capacity of umbilical cord blood-derived CD34+-enriched cells

Stem Cell Research & Therapy
2021-12 | Journal article
DOI: 10.1186/s13287-021-02474-8
Part of ISSN: 1757-6512
Source: Self-asserted source
Iris Caramalho

LRBA deficiency: a new genetic cause of monogenic lupus

Annals of the Rheumatic Diseases
2020-03 | Journal article
DOI: 10.1136/annrheumdis-2019-216410
Part of ISSN: 0003-4967
Part of ISSN: 1468-2060
Source: Self-asserted source
Iris Caramalho

The multifaceted Foxp3fgfp allele enhances spontaneous and therapeutic immune surveillance of cancer in mice

European Journal of Immunology
2020-03 | Journal article
DOI: 10.1002/eji.201948251
Contributors: José Almeida‐Santos; Marie‐Louise Bergman; Inês Amendoeira Cabral; Vasco Correia; Íris Caramalho; Jocelyne Demengeot
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Crossref

Children with type 1 diabetes of early age at onset – immune and metabolic phenotypes

Journal of Pediatric Endocrinology and Metabolism
2019-09-25 | Journal article
DOI: 10.1515/jpem-2019-0103
Part of ISSN: 2191-0251
Part of ISSN: 0334-018X
Source: Self-asserted source
Iris Caramalho

Expansion of FOXP3+ regulatory CD4 T cells upon exposure to hymenoptera venom during the beekeeping season

Allergy
2019-06 | Journal article
DOI: 10.1111/all.13713
Contributors: M. C. P. Santos; A. Serra‐Caetano; E. Pedro; A. Melo; I. Caramalho; M. P. Barbosa; R. M. M. Victorino; A. E. Sousa
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Crossref

MonoMAC Syndrome Caused by a Novel GATA2 Mutation Successfully Treated by Allogeneic Hematopoietic Stem Cell Transplantation

Journal of Clinical Immunology
2019-01 | Journal article
DOI: 10.1007/s10875-018-0576-x
Part of ISSN: 0271-9142
Part of ISSN: 1573-2592
Contributors: Moraes-Fontes; Íris Caramalho; Amy P. Hsu; Steven M. Holland; Manuel Abecasis
Source: Self-asserted source
Iris Caramalho

Fatal CTLA-4 heterozygosity with autoimmunity and recurrent infections: a de novo mutation

Clin Case Rep.
2017-11-06 | Journal article
DOI: 10.1002/ccr3.1257
Source: Self-asserted source
Iris Caramalho

Human naïve regulatory T-cells feature high steady-state turnover and are maintained by IL-7

Oncotarget
2016 | Journal article
DOI: 10.18632/oncotarget.7512
EID:

2-s2.0-84962891343
Contributors: Silva, S.L.; Albuquerque, A.S.; Serra-Caetano, A.; Foxall, R.B.; Pires, A.R.; Matoso, P.; Fernandes, S.M.; Ferreira, J.; Cheynier, R.; Victorino, R.M.M. et al.
Source: Self-asserted source
Iris Caramalho via Scopus - Elsevier

Bee venom enhances the differentiation of human regulatory T cells

Allergy: European Journal of Allergy and Clinical Immunology
2015 | Journal article
DOI: 10.1111/all.12691
EID:

2-s2.0-84942368921
Contributors: Caramalho, I.; Melo, A.; Pedro, E.; Barbosa, M.M.P.; Victorino, R.M.M.; Pereira Santos, M.C.; Sousa, A.E.
Source: Self-asserted source
Iris Caramalho via Scopus - Elsevier

Human regulatory T-cell development is dictated by Interleukin-2 and -15 expressed in a non-overlapping pattern in the thymus

Journal of Autoimmunity
2015 | Journal article
DOI: 10.1016/j.jaut.2014.11.002
EID:

2-s2.0-84920149783
Contributors: Caramalho, I.; Nunes-Silva, V.; Pires, A.R.; Mota, C.; Pinto, A.I.; Nunes-Cabaço, H.; Foxall, R.B.; Sousa, A.E.
Source: Self-asserted source
Iris Caramalho via Scopus - Elsevier

Predominant role of interferon-γ 3 in the host protective effect of CD8 + T cells against Neospora caninum infection

Scientific Reports
2015 | Journal article
DOI: 10.1038/srep14913
EID:

2-s2.0-84943770641
Contributors: Correia, A.; Ferreirinha, P.; Botelho, S.; Belinha, A.; Leitão, C.; Caramalho, I.; Teixeira, L.; González-Fernandéz, A.; Appelberg, R.; Vilanova, M.
Source: Self-asserted source
Iris Caramalho via Scopus - Elsevier

Regulatory T-cell development in the human thymus

Frontiers in Immunology
2015 | Journal article
DOI: 10.3389/fimmu.2015.00395
EID:

2-s2.0-84938506526
Contributors: Caramalho, Í.; Nunes-Cabaço, H.; Foxall, R.B.; Sousa, A.E.
Source: Self-asserted source
Iris Caramalho via Scopus - Elsevier

Delta-like 1-mediated notch signaling enhances the in vitro conversion of human memory CD4 T cells into FOXP3-expressing regulatory T cells

Journal of Immunology
2014 | Journal article
DOI: 10.4049/jimmunol.1400198
EID:

2-s2.0-84916877038
Contributors: Mota, C.; Nunes-Silva, V.; Pires, A.R.; Matoso, P.; Victorino, R.M.M.; Sousa, A.E.; Caramalho, I.
Source: Self-asserted source
Iris Caramalho via Scopus - Elsevier

Recent thymic emigrants are the preferential precursors of regulatory T cells differentiated in the periphery

Proceedings of the National Academy of Sciences of the United States of America
2013 | Journal article
DOI:

10.1073/pnas.1221955110
Contributors: Paiva, R.S.; Lino, A.C.; Bergman, M.-L.; Caramalho, I.; Sousa, A.E.; Zelenay, S.; Demengeot, J.
Source: Self-asserted source
Iris Caramalho via Scopus - Elsevier

The Genetic Basis of Escherichia coli Pathoadaptation to Macrophages

PLoS Pathogens
2013 | Journal article
DOI: 10.1371/journal.ppat.1003802
EID:

2-s2.0-84892897486
Contributors: Miskinyte, M.; Sousa, A.; Ramiro, R.S.; de Sousa, J.A.M.; Kotlinowski, J.; Caramalho, I.; Magalhães, S.; Soares, M.P.; Gordo, I.
Source: Self-asserted source
Iris Caramalho via Scopus - Elsevier

Differentiation of human thymic regulatory T cells at the double positive stage

European Journal of Immunology
2011 | Journal article
DOI:

10.1002/eji.201141614
Contributors: Nunes-Cabaço, H.; Caramalho, I.; Sepúlveda, N.; Sousa, A.E.
Source: Self-asserted source
Iris Caramalho via Scopus - Elsevier

Regulatory T cells Contribute to Diabetes Protection in Lipopolysaccharide-Treated Non-Obese Diabetic Mice

Scandinavian Journal of Immunology
2011 | Journal article
DOI:

10.1111/j.1365-3083.2011.02627.x
Contributors: Caramalho, I.; Rodrigues-Duarte, L.; Perez, A.; Zelenay, S.; Penha-Gonçalves, C.; Demengeot, J.
Source: Self-asserted source
Iris Caramalho via Scopus - Elsevier

Foxp3 induction in human and murine thymus precedes the CD4+ CD8+ stage but requires early T-cell receptor expression

Immunology and Cell Biology
2010 | Journal article
DOI:

10.1038/icb.2010.4
Contributors: Nunes-Cabaço, H.; Ribot, J.C.; Caramalho, I.; Serra-Caetano, A.; Silva-Santos, B.; Sousa, A.E.
Source: Self-asserted source
Iris Caramalho via Scopus - Elsevier

Inhibition of murine γδ lymphocyte expansion and effector function by regulatory αβ T cells is cell-contactdependent and sensitive to GITR modulation

European Journal of Immunology
2010 | Journal article
DOI:

10.1002/eji.200939715
Contributors: Gonçalves-Sousa, N.; Ribot, J.C.; DeBarros, A.; Correia, D.V.; Caramalho, Í.; Silva-Santos, B.
Source: Self-asserted source
Iris Caramalho via Scopus - Elsevier

Steroid treatments in mice do not alter the number and function of regulatory T cells, but amplify cyclophosphamide-induced autoimmune disease

Journal of Autoimmunity
2009 | Journal article
DOI:

10.1016/j.jaut.2009.03.008
Contributors: Moraes-Fontes, M.F.; Rebelo, M.; Caramalho, I.; Zelenay, S.; Bergman, M.-L.; Coutinho, A.; Demengeot, J.
Source: Self-asserted source
Iris Caramalho via Scopus - Elsevier

Visualizing CTL/melanoma cell interactions: Multiple hits must be delivered for tumour cell annihilation

Journal of Cellular and Molecular Medicine
2009 | Journal article
DOI:

10.1111/j.1582-4934.2008.00586.x
Contributors: Caramalho, Í.; Faroudi, M.; Padovan, E.; Müller, S.; Valitutti, S.
Source: Self-asserted source
Iris Caramalho via Scopus - Elsevier

Effects of intracellular calcium and actin cytoskeleton on TCR mobility measured by fluorescence recovery

PLoS ONE
2008 | Journal article
DOI:

10.1371/journal.pone.0003913
Contributors: Dushek, O.; Mueller, S.; Soubies, S.; Depoil, D.; Caramalho, I.; Coombs, D.; Valitutti, S.
Source: Self-asserted source
Iris Caramalho via Scopus - Elsevier

When three is not a crowd: A Crossregulation Model of the dynamics and repertoire selection of regulatory CD4+ T cells

Immunological Reviews
2007 | Journal article
DOI:

10.1111/j.1600-065X.2007.00487.x
Contributors: Carneiro, J.; Leon, K.; Caramalho, Í.; Van Den Dool, C.; Gardner, R.; Oliveira, V.; Bergman, M.-L.; Sepúlveda, N.; Paixão, T.; Faro, J. et al.
Source: Self-asserted source
Iris Caramalho via Scopus - Elsevier

Regulatory T cells in microbial infection

Springer Seminars in Immunopathology
2006 | Journal article
DOI:

10.1007/s00281-006-0024-5
Contributors: Demengeot, J.; Zelenay, S.; Moraes-Fontes, M.F.; Caramalho, Í.; Coutinho, A.
Source: Self-asserted source
Iris Caramalho via Scopus - Elsevier

Foxp3+ CD25- CD4 T cells constitute a reservoir of committed regulatory cells that regain CD25 expression upon homeostatic expansion

Proceedings of the National Academy of Sciences of the United States of America
2005 | Journal article
DOI:

10.1073/pnas.0408679102
Contributors: Zelenay, S.; Lopes-Carvalho, T.; Caramalho, I.; Moraes-Fontes, M.F.; Rebelo, M.; Demengeot, J.
Source: Self-asserted source
Iris Caramalho via Scopus - Elsevier

Thymic commitment of regulatory T cells is a pathway of TCR-dependent selection that isolates repertoires undergoing positive or negative selection

Current Topics in Microbiology and Immunology
2005 | Journal article
EID: 2-s2.0-20444396226
Contributors: Coutinho, A.; Caramalho, I.; Seixas, E.; Demengeot, J.
Source: Self-asserted source
Iris Caramalho via Scopus - Elsevier

Protection against systemic candidiasis in mice immunized with secreted aspartic proteinase 2

Immunology
2004 | Journal article
DOI:

10.1111/j.1365-2567.2004.01819.x
Contributors: Vilanova, M.; Teixeira, L.; Caramalho, Í.; Torrado, E.; Marques, A.; Madureira, P.; Ribeiro, A.; Ferreira, P.; Gama, M.; Demengeot, J.
Source: Self-asserted source
Iris Caramalho via Scopus - Elsevier

Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide

Journal of Experimental Medicine
2003 | Journal article
DOI:

10.1084/jem.20021633
Contributors: Caramalho, I.; Lopes-Carvalho, T.; Ostler, D.; Zelenay, S.; Haury, M.; Demengeot, J.
Source: Self-asserted source
Iris Caramalho via Scopus - Elsevier

IFn-α/β enhances BCR-dependent B cell responses

International Immunology
2002 | Journal article
EID: 2-s2.0-0036206908
Contributors: Braun, D.; Caramalho, I.; Demengeot, J.
Source: Self-asserted source
Iris Caramalho via Scopus - Elsevier

Regulatory T cells: The physiology of autoreactivity in dominant tolerance and "quality control" of immune responses

Immunological Reviews
2001 | Journal article
DOI:

10.1034/j.1600-065X.2001.1820107.x
Contributors: Coutinho, A.; Hori, S.; Carvalho, T.; Caramalho, I.; Demengeot, J.
Source: Self-asserted source
Iris Caramalho via Scopus - Elsevier
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