Personal information

Verified email domains

Japan

Activities

Employment (1)

Hokkaido University of Science: Sapporo, Hokkaido, JP

2018-04-01 to present | Associate Professor
Employment
Source: Self-asserted source
Kohei Togami

Education and qualifications (1)

Hokkaido University of Science: Sapporo, JP

2018-04 to present | Associate Professor (Faculty of Pharmaceutical Sciences)
Education
Source: Self-asserted source
Kohei Togami

Funding (8)

Pioneering research on development of "Drug Delivery System" for deworming gastrointestinal-infected Anisakis

2023-06-30 to 2026-03-31 | Grant
Japan Society for the Promotion of Science (Tokyo, JP)
GRANT_NUMBER: 23K17446
Source: Self-asserted source
Kohei Togami via DimensionsWizard

Development of epigenetic regulation techniques using drug delivery systems for kidney regeneration treatment

2022-06-30 to 2024-03-31 | Grant
Japan Society for the Promotion of Science (Tokyo, JP)
GRANT_NUMBER: 22K19941
Source: Self-asserted source
Kohei Togami via DimensionsWizard

アニサキス駆虫薬の探索とDDS創製:魚生食文化継承のため先人の研究挫折を超克する

2019-06-28 to 2021-03-31 | Grant
Japan Society for the Promotion of Science (Tokyo, JP)
GRANT_NUMBER: 19K22778
Source: Self-asserted source
Kohei Togami via DimensionsWizard

DDSと光イメージングが紡ぐ肺線維症の高感度かつ低リスクな病巣検出法の創出

2018-04-01 to 2021-03-31 | Grant
Japan Society for the Promotion of Science (Tokyo, JP)
GRANT_NUMBER: 18K12066
Source: Self-asserted source
Kohei Togami via DimensionsWizard

線維組織を足場とする放出制御型ナノ粒子による肺がん及び肺線維症治療システムの創製

2018-04-01 to 2021-03-31 | Grant
Japan Society for the Promotion of Science (Tokyo, JP)
GRANT_NUMBER: 18K06603
Source: Self-asserted source
Kohei Togami via DimensionsWizard

ライフスタイルに発症起因する難治性肺疾患の征圧基盤:肺投与型DDSがその扉を開く

2017-04-01 to 2021-03-31 | Grant
Japan Society for the Promotion of Science (Tokyo, JP)
GRANT_NUMBER: 17H02178
Source: Self-asserted source
Kohei Togami via DimensionsWizard

病巣の肺胞構造制御に基づく難治性呼吸器疾患治療DDSの創出

2015-04-01 to 2018-03-31 | Grant
Japan Society for the Promotion of Science (Tokyo, JP)
GRANT_NUMBER: 15K19165
Source: Self-asserted source
Kohei Togami via DimensionsWizard

Efficient delivery to fibrotic lesion of anti-fibrotic agents incorporated into nanoparticles for the treatment of idiopathic pulmonary fibrosis

2012-04-01 to 2015-03-31 | Grant
Japan Society for the Promotion of Science (Tokyo, JP)
GRANT_NUMBER: 24790167
Source: Self-asserted source
Kohei Togami via DimensionsWizard

Works (38)

Heterogenous Intrapulmonary Distribution of Aerosolized Model Compounds in Mice with Bleomycin-Induced Pulmonary Fibrosis

Journal of Aerosol Medicine and Pulmonary Drug Delivery
2023-12-01 | Journal article
Contributors: Kohei Togami; Yukimune Kanehira; Yuki Yumita; Hiroaki Ozaki; Rui Wang; Hitoshi Tada; Sumio Chono
Source: check_circle
Crossref

Development of a Compensated Förster Resonance Energy Transfer Imaging for Improved Assessment of the Intrapulmonary Distribution of Polymeric Nanoparticles

Journal of Pharmaceutical Sciences
2023-10 | Journal article
Contributors: Kohei Togami; Yoshiki Hazama; Yuki Nakamura; Kiyomi Ishizawa; Sumio Chono
Source: check_circle
Crossref

Development of visualization and analysis methods for evaluating intratumoral nanoparticle kinetics for tumor-targeted drug delivery using Förster resonance energy transfer in vivo live imaging and tissue clearing techniques

Journal of Pharmaceutical and Biomedical Analysis
2023-01 | Journal article
Contributors: Kohei Togami; Kiyomi Ishizawa; Mio Yasuda; Hitoshi Tada; Sumio Chono
Source: check_circle
Crossref

Improvement of the pharmacokinetics and antifibrotic effects of nintedanib by intrapulmonary administration of a nintedanib–hydroxypropyl-γ-cyclodextrin inclusion complex in mice with bleomycin-induced pulmonary fibrosis

European Journal of Pharmaceutics and Biopharmaceutics
2022-03 | Journal article
Part of ISSN: 0939-6411
Source: Self-asserted source
Kohei Togami

Aerosolized Liposomal Formulation Prevents Enhanced Drug Transfer from Fibrotic Lungs to the Systemic Circulation

Current Drug Delivery
2021-08 | Journal article
Contributors: Kohei Togami; Kaede Kurasho; Yukimune Kanehira; Hitoshi Tada; Sumio Chono
Source: check_circle
Crossref

Three-Dimensional Imaging of Pulmonary Fibrotic Foci at the Alveolar Scale Using Tissue-Clearing Treatment with Staining Techniques of Extracellular Matrix

International Journal of Biomedical Imaging
2020-12-29 | Journal article
Contributors: Kohei Togami; Hiroaki Ozaki; Yuki Yumita; Anri Kitayama; Hitoshi Tada; Sumio Chono; D. L. Wilson
Source: check_circle
Crossref

Prolonged distribution of aerosolized PEGylated liposomes in the lungs of mice with bleomycin-induced pulmonary fibrosis

Drug Development and Industrial Pharmacy
2020-11-01 | Journal article
Contributors: Kohei Togami; Yuki Maruta; Mao Nanbu; Hitoshi Tada; Sumio Chono
Source: check_circle
Crossref

Evaluation of Tissue-Clearing Techniques for Intraorgan Imaging of Distribution of Polymeric Nanoparticles as Drug Carriers

Drug Development and Industrial Pharmacy
2020-10-29 | Journal article
Part of ISSN: 0363-9045
Part of ISSN: 1520-5762
Source: Self-asserted source
Kohei Togami
grade
Preferred source (of 3)‎

Assessment of transporter-mediated efflux of nintedanib using in vitro cell line models of idiopathic pulmonary fibrosis.

Die Pharmazie
2020-08-01 | Journal article
Source: Self-asserted source
Kohei Togami

Intrapulmonary Pharmacokinetics and Drug Distribution Characteristics for the Treatment of Respiratory Diseases

YAKUGAKU ZASSHI
2020-03-01 | Journal article
Part of ISSN: 0031-6903
Part of ISSN: 1347-5231
Source: Self-asserted source
Kohei Togami

Intratumoral delivery and therapeutic efficacy of nanoparticle-encapsulated anti-tumor siRNA following intrapulmonary administration for potential treatment of lung cancer

Pharmaceutical Development and Technology
2019-06-17 | Journal article
Part of ISSN: 1083-7450
Part of ISSN: 1097-9867
Source: Self-asserted source
Kohei Togami
grade
Preferred source (of 2)‎

Evaluation of various tissue-clearing techniques for the three-dimensional visualization of liposome distribution in mouse lungs at the alveolar scale

International Journal of Pharmaceutics
2019-05 | Journal article
Part of ISSN: 0378-5173
Source: Self-asserted source
Kohei Togami
grade
Preferred source (of 2)‎

Tissue-clearing techniques enable three-dimensional visualization of aerosolized model compound and lung structure at the alveolar scale

Biological and Pharmaceutical Bulletin
2018 | Journal article
EID:

2-s2.0-85040120764

Contributors: Togami, K.; Kitayama, A.; Daisho, T.; Wang, R.; Tada, H.; Chono, S.
Source: Self-asserted source
Kohei Togami via Scopus - Elsevier

Usability of theophylline extended-release dry syrups

Journal of Generic Medicines: The Business Journal for the Generic Medicines Sector
2018-12 | Journal article
Part of ISSN: 1741-1343
Part of ISSN: 1741-7090
Source: Self-asserted source
Kohei Togami

Taste and dissolution of theophylline extended-release dry syrups

Journal of Generic Medicines: The Business Journal for the Generic Medicines Sector
2018-09 | Journal article
Part of ISSN: 1741-1343
Part of ISSN: 1741-7090
Source: Self-asserted source
Kohei Togami

The Effect of Dexmedetomidine on Oral Mucosal Blood Flow and the Absorption of Lidocaine

Anesthesia Progress
2018-09 | Journal article
Part of ISSN: 0003-3006
Source: Self-asserted source
Kohei Togami

Aerosolized liposomes with dipalmitoyl phosphatidylcholine enhance pulmonary absorption of encapsulated insulin compared with co-administered insulin

Drug Development and Industrial Pharmacy
2017 | Journal article
EID:

2-s2.0-85025833670

Contributors: Chono, S.; Togami, K.; Itagaki, S.
Source: Self-asserted source
Kohei Togami via Scopus - Elsevier

Evaluation of permeability alteration and epithelial–mesenchymal transition induced by transforming growth factor-β<inf>1</inf>in A549, NCI-H441, and Calu-3 cells: Development of an in vitro model of respiratory epithelial cells in idiopathic pulmonary fibrosis

Journal of Pharmacological and Toxicological Methods
2017 | Journal article
EID:

2-s2.0-85014356306

Contributors: Togami, K.; Yamaguchi, K.; Chono, S.; Tada, H.
Source: Self-asserted source
Kohei Togami via Scopus - Elsevier
grade
Preferred source (of 2)‎

Storage stability of serum formulations containing ofloxacin for autologous serum eardrop therapy

Pharmazie
2017 | Journal article
EID:

2-s2.0-85017292927

Contributors: Hashimoto, N.; Togami, K.; Endou, K.; Onodera, H.; Tanimoto, H.; Itagaki, S.; Chono, S.
Source: Self-asserted source
Kohei Togami via Scopus - Elsevier

Alteration in Intrapulmonary Pharmacokinetics of Aerosolized Model Compounds Due to Disruption of the Alveolar Epithelial Barriers Following Bleomycin-Induced Pulmonary Fibrosis in Rats

Journal of Pharmaceutical Sciences
2016 | Journal article
EID:

2-s2.0-84964425168

Contributors: Togami, K.; Chono, S.; Tada, H.
Source: Self-asserted source
Kohei Togami via Scopus - Elsevier

Sustained distribution of aerosolized PEGylated liposomes in epithelial lining fluids on alveolar surfaces

Drug Delivery and Translational Research
2016 | Journal article
EID:

2-s2.0-84983670540

Contributors: Kaneko, K.; Togami, K.; Yamamoto, E.; Wang, S.; Morimoto, K.; Itagaki, S.; Chono, S.
Source: Self-asserted source
Kohei Togami via Scopus - Elsevier

Tumor distribution and anti-tumor effect of doxorubicin following intrapulmonary administration to mice with metastatic lung tumor

Journal of Drug Delivery Science and Technology
2016 | Journal article
EID:

2-s2.0-84964341640

Contributors: Kanehira, Y.; Togami, K.; Tada, H.; Chono, S.
Source: Self-asserted source
Kohei Togami via Scopus - Elsevier

Efficient delivery to human lung fibroblasts (WI-38) of pirfenidone incorporated into liposomes modified with truncated basic fibroblast growth factor and its inhibitory effect on collagen synthesis in idiopathic pulmonary fibrosis

Biological and Pharmaceutical Bulletin
2015 | Journal article
EID:

2-s2.0-84922345721

Contributors: Togami, K.; Miyao, A.; Miyakoshi, K.; Kanehira, Y.; Tada, H.; Chono, S.
Source: Self-asserted source
Kohei Togami via Scopus - Elsevier

Pharmacokinetic evaluation of tissue distribution of pirfenidone and its metabolites for idiopathic pulmonary fibrosis therapy

Biopharmaceutics and Drug Disposition
2015 | Journal article
EID:

2-s2.0-84941745499

Contributors: Togami, K.; Kanehira, Y.; Tada, H.
Source: Self-asserted source
Kohei Togami via Scopus - Elsevier

Involvement of intestinal permeability in the oral absorption of clarithromycin and telithromycin

Biopharmaceutics and Drug Disposition
2014 | Journal article
EID:

2-s2.0-84922211802

Contributors: Togami, K.; Hayashi, Y.; Chono, S.; Morimoto, K.
Source: Self-asserted source
Kohei Togami via Scopus - Elsevier

Aerosol-based efficient delivery of azithromycin to alveolar macrophages for treatment of respiratory infections

Pharmaceutical Development and Technology
2013 | Journal article
EID:

2-s2.0-84883381121

Contributors: Togami, K.; Chono, S.; Morimoto, K.
Source: Self-asserted source
Kohei Togami via Scopus - Elsevier

Dexmedetomidine decreases the oral mucosal blood flow

British Journal of Oral and Maxillofacial Surgery
2013 | Journal article
EID:

2-s2.0-84889880325

Contributors: Kawaai, H.; Yoshida, K.; Tanaka, E.; Togami, K.; Tada, H.; Ganzberg, S.; Yamazaki, S.
Source: Self-asserted source
Kohei Togami via Scopus - Elsevier

Enantioselective uptake of fexofenadine by Caco-2 cells as model intestinal epithelial cells

Journal of Pharmacy and Pharmacology
2013 | Journal article
EID:

2-s2.0-84870860939

Contributors: Togami, K.; Tosaki, Y.; Chono, S.; Morimoto, K.; Hayasaka, M.; Tada, H.
Source: Self-asserted source
Kohei Togami via Scopus - Elsevier

Possible involvement of pirfenidone metabolites in the antifibrotic action of a therapy for idiopathic pulmonary fibrosis

Biological and Pharmaceutical Bulletin
2013 | Journal article
EID:

2-s2.0-84887117377

Contributors: Togami, K.; Kanehira, Y.; Tada, H.
Source: Self-asserted source
Kohei Togami via Scopus - Elsevier

Subcellular distribution of azithromycin and clarithromycin in rat alveolar macrophages (NR8383) in Vitro

Biological and Pharmaceutical Bulletin
2013 | Journal article
EID:

2-s2.0-84884648979

Contributors: Togami, K.; Chono, S.; Morimoto, K.
Source: Self-asserted source
Kohei Togami via Scopus - Elsevier

Aerosol-based efficient delivery of clarithromycin, a macrolide antimicrobial agent, to lung epithelial lining fluid and alveolar macrophages for treatment of respiratory infections

Journal of Aerosol Medicine and Pulmonary Drug Delivery
2012 | Journal article
EID:

2-s2.0-84859398578

Contributors: Togami, K.; Chono, S.; Morimoto, K.
Source: Self-asserted source
Kohei Togami via Scopus - Elsevier

Transport characteristics of clarithromycin, azithromycin and telithromycin, antibiotics applied for treatment of respiratory infections, in Calu-3 cell monolayers as model lung epithelial cells

Pharmazie
2012 | Journal article
EID:

2-s2.0-84862321766

Contributors: Togami, K.; Chono, S.; Morimoto, K.
Source: Self-asserted source
Kohei Togami via Scopus - Elsevier

Distribution characteristics of clarithromycin and azithromycin, macrolide antimicrobial agents used for treatment of respiratory infections, in lung epithelial lining fluid and alveolar macrophages

Biopharmaceutics and Drug Disposition
2011 | Journal article
EID:

2-s2.0-80053179622

Contributors: Togami, K.; Chono, S.; Morimoto, K.
Source: Self-asserted source
Kohei Togami via Scopus - Elsevier

Efficient drug delivery to lung epithelial lining fluid by aerosolization of ciprofloxacin incorporated into PEGylated liposomes for treatment of respiratory infections

Drug Development and Industrial Pharmacy
2011 | Journal article
EID:

2-s2.0-79953253279

Contributors: Chono, S.; Suzuki, H.; Togami, K.; Morimoto, K.
Source: Self-asserted source
Kohei Togami via Scopus - Elsevier

Aerosol-based efficient delivery of telithromycin, a ketolide antimicrobial agent, to lung epithelial lining fluid and alveolar macrophages for treatment of respiratory infections

Drug Development and Industrial Pharmacy
2010 | Journal article
EID:

2-s2.0-77953195425

Contributors: Togami, K.; Chono, S.; Seki, T.; Morimoto, K.
Source: Self-asserted source
Kohei Togami via Scopus - Elsevier

Effect of surface-mannose modification on aerosolized liposomal delivery to alveolar macrophages

Drug Development and Industrial Pharmacy
2010 | Journal article
EID:

2-s2.0-74949118665

Contributors: Chono, S.; Kaneko, K.; Yamamoto, E.; Togami, K.; Morimoto, K.
Source: Self-asserted source
Kohei Togami via Scopus - Elsevier

Intracellular pharmacokinetics of telithromycin, a ketolide antibiotic, in alveolar macrophages

Journal of Pharmacy and Pharmacology
2010 | Journal article
EID:

2-s2.0-77949533787

Contributors: Togami, K.; Chono, S.; Seki, T.; Morimoto, K.
Source: Self-asserted source
Kohei Togami via Scopus - Elsevier

Distribution characteristics of telithromycin, a novel ketolide antimicrobial agent applied for treatment of respiratory infection, in lung epithelial lining fluid and alveolar macrophages

Drug Metabolism and Pharmacokinetics
2009 | Journal article
EID:

2-s2.0-71449110365

Contributors: Togami, K.; Chono, S.; Seki, T.; Morimoto, K.
Source: Self-asserted source
Kohei Togami via Scopus - Elsevier

Peer review (4 reviews for 3 publications/grants)

Review activity for Advanced science. (1)
Review activity for Carbohydrate polymers. (2)
Review activity for Molecular pharmaceutics. (1)