Personal information

Activities

Employment (2)

University of Colorado Denver School of Medicine: Aurora, CO, US

2018-11-01 to present | Associate Professor (Anesthesiology)
Employment
Source: Self-asserted source
Fabrice Dabertrand

University of Vermont College of Medicine: Burlington, VT, US

2014-01-01 to 2018-10-31 | Assistant Professor (Pharmacology)
Employment
Source: Self-asserted source
Fabrice Dabertrand

Education and qualifications (3)

University of Vermont College of Medicine: Burlington, VT, US

2009-01-01 to 2013-12-31 | Post-doctoral Fellow (Pharmacology)
Education
Source: Self-asserted source
Fabrice Dabertrand

Université de Bordeaux UFR Sciences et Technologies: Talence, Aquitaine, FR

2006-12-01 to 2008-11-30 | Post-doctoral Fellow (Center for Cognitive and Integrative Neurosciences)
Education
Source: Self-asserted source
Fabrice Dabertrand

Université de Bordeaux UFR des Sciences Médicales: Bordeaux, Aquitaine, FR

2004-07-01 to 2006-11-27 | Ph. D. (Neuroscience)
Education
Source: Self-asserted source
Fabrice Dabertrand

Professional activities (5)

Microcirculatory Society: Columbia, Missouri, US

2019 to present | Member
Membership
Source: Self-asserted source
Fabrice Dabertrand

International Society of Cerebral Blood Flow and Metabolism: Bethesda, MD, US

2019 to present | Member
Membership
Source: Self-asserted source
Fabrice Dabertrand

The Society of General Physiologists: DC, DC, US

2015 to present | Member
Membership
Source: Self-asserted source
Fabrice Dabertrand

American Physiological Society: Bethesda, MD, US

2012 to present | Member
Membership
Source: Self-asserted source
Fabrice Dabertrand

American Society for Pharmacology and Experimental Therapeutics: Bethesda, MD, US

2009 to present | Member
Membership
Source: Self-asserted source
Fabrice Dabertrand

Funding (4)

Advance in PIP2 treatment to restore capillary blood flow

2023-03 to 2034-02 | Grant
Orphan Disease Center, Perelman School of Medicine, University of Pennsylvania (PA, PA, US)
Source: Self-asserted source
Fabrice Dabertrand

Rescuing neurovascular coupling to protect neuronal plasticity and cognition

2022-07-15 to 2025-06-30 | Grant
National Institute of Neurological Disorders and Stroke (Bethesda, US)
GRANT_NUMBER: RF1NS129022
Source: Self-asserted source
Fabrice Dabertrand via DimensionsWizard

Capillary control of cerebral blood flow, and its disruption in small vessel disease

2017-02-01 to 2023-02-28 | Grant
National Heart Lung and Blood Institute (Bethesda, US)
GRANT_NUMBER: R01HL136636
Source: Self-asserted source
Fabrice Dabertrand via DimensionsWizard

RyR3 splice variants determine fundamental calcium signaling processes in cerebral arteries

2009-07-01 to 2011-06-30 | Grant
American Heart Association (Dallas, US)
GRANT_NUMBER:

09POST2290090

Source: Self-asserted source
Fabrice Dabertrand via DimensionsWizard

Works (33)

Sweet relief: make the brain Glo against diabetic cognitive fog

The Journal of Physiology
2024-11 | Journal article
Contributors: Fabrice Dabertrand
Source: check_circle
Crossref

Harnessing micrometer-scale tPA beads for high plasmin generation and accelerated fibrinolysis

2024-11-08 | Preprint
Contributors: Matthew J. Osmond; Fabrice Dabertrand; Nidia Quillinan; Enming J. Su; Daniel A. Lawrence; David W.M. Marr; Keith B. Neeves
Source: check_circle
Crossref

Estrogen regulates myogenic tone in hippocampal arterioles by enhanced basal release of nitric oxide and endothelial SKCachannel activity

2023-08-17 | Preprint
Contributors: Danielle A. Jeffrey; Abigail Russell; Mayra Bueno Guerrero; Jackson T. Fontaine; Phinea Romero; Amanda C. Rosehart; Fabrice Dabertrand
Source: check_circle
Crossref

Ex vivo capillary-parenchymal arteriole approach to study brain pericyte physiology.

Neurophotonics
2022-06-23 | Journal article | Author
Contributors: DANIELLE JEFFREY; Fontaine JT; Fabrice Dabertrand
Source: Self-asserted source
Fabrice Dabertrand

Differential restoration of functional hyperemia by antihypertensive drug classes in hypertension-related cerebral small vessel disease

Journal of Clinical Investigation
2021-09-15 | Journal article
Contributors: Masayo Koide; Osama F. Harraz; Fabrice Dabertrand; Thomas A. Longden; Hannah R. Ferris; George C. Wellman; David C. Hill-Eubanks; Adam S. Greenstein; Mark T. Nelson
Source: check_circle
Crossref

Prostaglandin E2 Dilates Intracerebral Arterioles When Applied to Capillaries: Implications for Small Vessel Diseases.

Frontiers in aging neuroscience
2021-08-13 | Journal article
Contributors: Fabrice Dabertrand; Longden TA; Weir N; Fontaine JT; Anne Joutel; Dabertrand F
Source: Self-asserted source
Fabrice Dabertrand

PIP 2 corrects cerebral blood flow deficits in small vessel disease by rescuing capillary Kir2.1 activity

Proceedings of the National Academy of Sciences
2021-04-27 | Journal article
Contributors: Fabrice Dabertrand; Osama F. Harraz; Masayo Koide; Thomas A. Longden; Amanda C. Rosehart; David C. Hill-Eubanks; Anne Joutel; Mark T. Nelson
Source: check_circle
Crossref

HB-EGF depolarizes hippocampal arterioles to restore myogenic tone in a genetic model of small vessel disease.

Mechanisms of ageing and development
2020-10-27 | Journal article
Contributors: Fabrice Dabertrand; Fontaine JT; Amanda Rosehart; Anne Joutel; Dabertrand F
Source: Self-asserted source
Fabrice Dabertrand

The capillary Kir channel as sensor and amplifier of neuronal signals: Modeling insights on K + -mediated neurovascular communication

Proceedings of the National Academy of Sciences
2020-07-14 | Journal article
Contributors: Arash Moshkforoush; Baarbod Ashenagar; Osama F. Harraz; Fabrice Dabertrand; Thomas A. Longden; Mark T. Nelson; Nikolaos M. Tsoukias
Source: check_circle
Crossref

Reducing Hypermuscularization of the Transitional Segment Between Arterioles and Capillaries Protects Against Spontaneous Intracerebral Hemorrhage.

Circulation
2020-03-18 | Journal article
Source: Self-asserted source
Fabrice Dabertrand

Ex Vivo Pressurized Hippocampal Capillary-Parenchymal Arteriole Preparation for Functional Study

Journal of Visualized Experiments
2019-12-18 | Journal article
Part of ISSN: 1940-087X
Source: Self-asserted source
Fabrice Dabertrand

Endothelial GqPCR activity controls capillary electrical signaling and brain blood flow through PIP 2 depletion

Proceedings of the National Academy of Sciences
2018-04-10 | Journal article
Contributors: Osama F. Harraz; Thomas A. Longden; Fabrice Dabertrand; David Hill-Eubanks; Mark T. Nelson
Source: check_circle
Crossref

Changes in Cerebral Arteries and Parenchymal Arterioles With Aging: Role of Rho Kinase 2 and Impact of Genetic Background.

Hypertension
2018-04-01 | Journal article
Source: Self-asserted source
Fabrice Dabertrand

The yin and yang of KV channels in cerebral small vessel pathologies

Microcirculation
2018-01 | Journal article
Contributors: Masayo Koide; Arash Moshkforoush; Nikolaos M. Tsoukias; David C. Hill‐Eubanks; George C. Wellman; Mark T. Nelson; Fabrice Dabertrand
Source: check_circle
Crossref

Capillary K<sup>+</sup>-sensing initiates retrograde hyperpolarization to increase local cerebral blood flow

Nature Neuroscience
2017 | Journal article
EID:

2-s2.0-85015683909

Contributors: Longden, T.A.; Dabertrand, F.; Koide, M.; Gonzales, A.L.; Tykocki, N.R.; Brayden, J.E.; Hill-Eubanks, D.; Nelson, M.T.
Source: Self-asserted source
Fabrice Dabertrand via Scopus - Elsevier

Isolation and cannulation of cerebral parenchymal arterioles

Journal of Visualized Experiments
2016 | Journal article
EID:

2-s2.0-84971531828

Contributors: Pires, P.W.; Dabertrand, F.; Earley, S.
Source: Self-asserted source
Fabrice Dabertrand via Scopus - Elsevier

Mechanistic insights into a TIMP3-sensitive pathway constitutively engaged in the regulation of cerebral hemodynamics

eLife
2016 | Journal article
EID:

2-s2.0-84983642499

Contributors: Capone, C.; Dabertrand, F.; Baron-Menguy, C.; Chalaris, A.; Ghezali, L.; Domenga-Denier, V.; Schmidt, S.; Huneau, C.; Rose-John, S.; Nelson, M.T. et al.
Source: Self-asserted source
Fabrice Dabertrand via Scopus - Elsevier

Blood brain barrier precludes the cerebral arteries to intravenously-injected antisense oligonucleotide.

European Journal of Pharmacology
2015 | Journal article
EID:

2-s2.0-84919784502

Contributors: Boursereau, R.; Donadieu, A.; Dabertrand, F.; Dubayle, D.; Morel, J.-L.
Source: Self-asserted source
Fabrice Dabertrand via Scopus - Elsevier

Potassium channelopathy-like defect underlies early-stage cerebrovascular dysfunction in a genetic model of small vessel disease

Proceedings of the National Academy of Sciences of the United States of America
2015 | Journal article
EID:

2-s2.0-84923169823

Contributors: Dabertrand, F.; Krøigaard, C.; Bonev, A.D.; Cognat, E.; Dalsgaar, T.; Domenga-Denier, V.; Hill-Eubanks, D.C.; Braydena, J.E.; Joutel, A.; Nelson, M.T.
Source: Self-asserted source
Fabrice Dabertrand via Scopus - Elsevier

A PLCγ1-dependent, force-sensitive signaling network in the myogenic constriction of cerebral arteries

Science Signaling
2014 | Journal article
EID:

2-s2.0-84901944514

Contributors: Gonzales, A.L.; Yang, Y.; Sullivan, M.N.; Sanders, L.; Dabertrand, F.; Hill-Eubanks, D.C.; Nelson, M.T.; Earley, S.
Source: Self-asserted source
Fabrice Dabertrand via Scopus - Elsevier

Stress-induced glucocorticoid signaling remodels neurovascular coupling through impairment of cerebrovascular inwardly rectifying K+ channel function

Proceedings of the National Academy of Sciences of the United States of America
2014 | Journal article
EID:

2-s2.0-84901045159

Contributors: Longden, T.A.; Dabertrand, F.; Hill-Eubanks, D.C.; Hammack, S.E.; Nelson, M.T.
Source: Self-asserted source
Fabrice Dabertrand via Scopus - Elsevier

Up-regulation of ryanodine receptor expression increases the calcium-induced calcium release and spontaneous calcium signals in cerebral arteries from hindlimb unloaded rats

Pflugers Archiv European Journal of Physiology
2014 | Journal article
EID:

2-s2.0-84904269930

Contributors: Morel, J.-L.; Dabertrand, F.; Porte, Y.; Prevot, A.; Macrez, N.
Source: Self-asserted source
Fabrice Dabertrand via Scopus - Elsevier

Prostaglandin E2, a postulated astrocyte-derived neurovascular coupling agent, constricts rather than dilates parenchymal arterioles

Journal of Cerebral Blood Flow and Metabolism
2013 | Journal article
EID:

2-s2.0-84876418668

Contributors: Dabertrand, F.; Hannah, R.M.; Pearson, J.M.; Hill-Eubanks, D.C.; Brayden, J.E.; Nelson, M.T.
Source: Self-asserted source
Fabrice Dabertrand via Scopus - Elsevier

Ryanodine Receptors, Calcium Signaling, and Regulation of Vascular tone in the cerebral parenchymal microcirculation

Microcirculation
2013 | Journal article
EID:

2-s2.0-84877664270

Contributors: Dabertrand, F.; Nelson, M.T.; Brayden, J.E.
Source: Self-asserted source
Fabrice Dabertrand via Scopus - Elsevier

Acidosis dilates brain parenchymal arterioles by conversion of calcium waves to sparks to activate BK channels

Circulation Research
2012 | Journal article
EID:

2-s2.0-84856062857

Contributors: Dabertrand, F.; Nelson, M.T.; Brayden, J.E.
Source: Self-asserted source
Fabrice Dabertrand via Scopus - Elsevier

Spaceflight regulates ryanodine receptor subtype 1 in portal vein myocytes in the opposite way of hypertension

Journal of Applied Physiology
2012 | Journal article
EID:

2-s2.0-84856853367

Contributors: Dabertrand, F.; Porte, Y.; MacRez, N.; Morel, J.-L.
Source: Self-asserted source
Fabrice Dabertrand via Scopus - Elsevier

Comparison between gentamycin and exon skipping treatments to restore ryanodine receptor subtype 2 functions in mdx mouse duodenum myocytes

European Journal of Pharmacology
2010 | Journal article
EID:

2-s2.0-73649125251

Contributors: Dabertrand, F.; Mironneau, J.; Henaff, M.; Macrez, N.; Morel, J.-L.
Source: Self-asserted source
Fabrice Dabertrand via Scopus - Elsevier

The decrease of expression of ryanodine receptor sub-type 2 is reversed by gentamycin sulphate in vascular myocytes from mdx mice

Journal of Cellular and Molecular Medicine
2009 | Journal article
EID:

2-s2.0-77449153149

Contributors: Morel, J.-L.; Dabertrand, F.; Fritz, N.; Henaff, M.; Mironneau, J.; Macrez, N.
Source: Self-asserted source
Fabrice Dabertrand via Scopus - Elsevier

Acetylcholine evokes an InsP3R1-dependent transient Ca 2+ signal in rat duodenum myocytes

Canadian Journal of Physiology and Pharmacology
2008 | Journal article
EID:

2-s2.0-50849112414

Contributors: Fritz, N.; Dabertrand, F.; Mironneau, J.; Macrez, N.; Morel, J.-L.
Source: Self-asserted source
Fabrice Dabertrand via Scopus - Elsevier

Full length ryanodine receptor subtype 3 encodes spontaneous calcium oscillations in native duodenal smooth muscle cells

Cell Calcium
2008 | Journal article
EID:

2-s2.0-45049087942

Contributors: Dabertrand, F.; Mironneau, J.; Macrez, N.; Morel, J.-L.
Source: Self-asserted source
Fabrice Dabertrand via Scopus - Elsevier

Role of RYR3 splice variants in calcium signaling in mouse nonpregnant and pregnant myometrium

American Journal of Physiology - Cell Physiology
2007 | Journal article
EID:

2-s2.0-34548763917

Contributors: Dabertrand, F.; Fritz, N.; Mironneau, J.; Macrez, N.; Morel, J.-L.
Source: Self-asserted source
Fabrice Dabertrand via Scopus - Elsevier

Strain differences in hypothalamic-pituitary-adrenocortical axis function and adipogenic effects of corticosterone in rats

Journal of Endocrinology
2007 | Journal article
EID:

2-s2.0-38349075003

Contributors: Marissal-Arvy, N.; Gaumont, A.; Langlois, A.; Dabertrand, F.; Bouchecareilh, M.; Tridon, C.; Mormede, P.
Source: Self-asserted source
Fabrice Dabertrand via Scopus - Elsevier

Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells

Cell Calcium
2006 | Journal article
EID:

2-s2.0-33646777149

Contributors: Dabertrand, F.; Morel, J.-L.; Sorrentino, V.; Mironneau, J.; Mironneau, C.; Macrez, N.
Source: Self-asserted source
Fabrice Dabertrand via Scopus - Elsevier

Peer review (22 reviews for 10 publications/grants)

Review activity for American Heart Association (4)
Review activity for British journal of pharmacology. (4)
Review activity for Cell reports. (1)
Review activity for eLife (3)
Review activity for Microcirculation (4)
Review activity for Nature communications (1)
Review activity for Pharmacological research. (1)
Review activity for Proceedings of the National Academy of Sciences of the United States of America. (2)
Review activity for The Journal of general physiology. (1)
Review activity for The journal of general physiology. (1)