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Editorial: Nuclear Medicine in the Context of Personalized Medicine

Frontiers in Medicine
2020 | Journal article
DOI: 10.3389/FMED.2020.00252
WOSUID: WOS:000543452900001
Contributors: Barbet, Jacques; Bernaudin, Myriam; Payoux, Pierre; Cicone, Francesco; Gaugler, Marie-Helene; Kraeber-Bodere, Francoise
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Secretion of Acid Sphingomyelinase and Ceramide by Endothelial Cells Contributes to Radiation-Induced Intestinal Toxicity

Cancer Research
2020 | Journal article
DOI: 10.1158/0008-5472.CAN-19-1527
WOSUID: WOS:000541824200022
Contributors: Leonetti, Daniela; Estephan, Hala; Ripoche, Natacha; Dubois, Nolwenn; Aguesse, Audrey; Gouard, Sebastien; Brossard, Lisa; Chiavassa, Sophie; Corre, Isabelle; Pecqueur, Claire et al.
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Secreted acid sphingomyelinase and ceramide contribute to radiation-induced intestinal toxicity

Radiotherapy and Oncology
2018 | Journal article
DOI: 10.1016/S0167-8140(18)30895-8
WOSUID: WOS:000437723401190
Contributors: Estephan, H.; Leonetti, D.; Gaugler, M. H.; Hadchity, E.; Corre, I.; Paris, F.
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Editorial: innovative radiopharmaceuticals in oncology and Neurology

Frontiers in Medicine
2017 | Journal article
DOI: 10.3389/FMED.2016.00074
WOSUID: WOS:000407078900001
Contributors: Barbet, Jacques; Barbet, Jacques; Arlicot, Nicolas; Arlicot, Nicolas; Gaugler, Marie-Helene; Gaugler, Marie-Helene; Cherel, Michel; Cherel, Michel; Guilloteau, Denis; Guilloteau, Denis et al.
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Ionizing radiation induces long-term senescence in endothelial cells through mitochondrial respiratory complex II dysfunction and superoxide generation

Free Radical Biology and Medicine
2017 | Journal article
DOI: 10.1016/J.FREERADBIOMED.2017.04.019
WOSUID: WOS:000403463500066
Contributors: Lafargue, Audrey; Degorre, Charlotte; Corre, Isabelle; Alves-Guerra, Marie-Clotilde; Gaugler, Marie-Helene; Vallette, Francois; Pecqueur, Claire; Paris, Francois
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Plasma membrane reorganization links acid sphingomyelinase/ceramide to p38 MAPK pathways in endothelial cells apoptosis

Cellular Signalling
2017-05 | Journal article
DOI: 10.1016/j.cellsig.2017.02.001
Contributors: Colin Niaudet; Stéphanie Bonnaud; Maëva Guillonneau; Sébastien Gouard; Marie-Hélène Gaugler; Soizic Dutoit; Natacha Ripoche; Nolwenn Dubois; Valérie Trichet; Isabelle Corre et al.
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Plasma ceramide, a real-time predictive marker of pulmonary and hepatic metastases response to stereotactic body radiation therapy combined with irinotecan

Radiotherapy and Oncology
2016 | Journal article
DOI: 10.1016/J.RADONC.2016.03.014
WOSUID: WOS:000379559400007
Contributors: Dubois, Nolwenn; Rio, Emmanuel; Ripoche, Natacha; Ferchaud-Roucher, Veronique; Gaugler, Marie-Helene; Campion, Loic; Krempf, Michel; Carrie, Christian; Mahe, Marc; Mirabel, Xavier et al.
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Therapeutic Efficacy of Alpha-RIT Using a Bi-213-Anti-hcD138 Antibody in a Mouse Model of Ovarian Peritoneal Carcinomatosis

Frontiers in Medicine
2015 | Journal article
DOI: 10.3389/FMED.2015.00088
WOSUID: WOS:000219268400085
Contributors: Derrien, Aurelie; Gouard, Sebastien; Maurel, Catherine; Gaugler, Marie-Helene; Bruchertseifer, Frank; Morgenstem, Alfred; Faivre-Chauvet, Alain; Classe, Jean-Marc; Cherel, Michel
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Inhibition of tumor angiogenesis by globotriaosylceramide immunotargeting

OncoImmunology
2013 | Journal article
DOI: 10.4161/ONCI.23700
WOSUID: WOS:000322566200001
Contributors: Birkle, Stephane; Desselle, Ariane; Chaumette, Tanguy; Gaugler, Marie-Helene; Cochonneau, Denis; Fleurence, Julien; Dubois, Nolwenn; Hulin, Philippe; Aubry, Jacques; Paris, Francois
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Anti-Gb3 Monoclonal Antibody Inhibits Angiogenesis and Tumor Development

Plos One
2012 | Journal article
DOI: 10.1371/JOURNAL.PONE.0045423
WOSUID: WOS:000311929800002
Contributors: Desselle, Ariane; Chaumette, Tanguy; Gaugler, Marie-Helene; Cochonneau, Denis; Fleurence, Julien; Dubois, Nolwenn; Hulin, Philippe; Aubry, Jacques; Birkle, Stephane; Paris, Francois
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Les effets des rayonnements ionisants sur le système cardiovasculaire

Radioprotection
2011 | Journal article
DOI: 10.1051/RADIOPRO/2011141
WOSUID: WOS:000299445200004
Contributors: F. Milliat; M. Benderitter; M.-H. Gaugler
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RhoA GTPase regulates radiation-induced alterations in endothelial cell adhesion and migration

Biochemical and Biophysical Research Communications
2011 | Journal article
DOI: 10.1016/J.BBRC.2011.09.150
WOSUID: WOS:000297088600019
Contributors: Rousseau, Matthieu; Gaugler, Marie-Helene; Rodallec, Audrey; Bonnaud, Stephanie; Paris, Francois; Corre, Isabelle
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Radiothérapie et athérome

Médecine/sciences
2010 | Journal article
DOI: 10.1051/MEDSCI/2010268-9740
WOSUID: WOS:000282085900018
Contributors: Marie-Hélène Gaugler; Franck Drouet; Michel Krempf
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Sphingosine-1-Phosphate Activates the AKT Pathway to Protect Small Intestines from Radiation-Induced Endothelial Apoptosis

Cancer Research
2010 | Journal article
DOI: 10.1158/0008-5472.CAN-10-2043
WOSUID: WOS:000285045900040
Contributors: S. Bonnaud; C. Niaudet; F. Legoux; I. Corre; G. Delpon; X. Saulquin; Z. Fuks; M.-H. Gaugler; R. Kolesnick; F. Paris
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CRITICAL ROLE OF ACID SPHINGOMYELINASE (ASM) IN INTESTINAL DYSFUNCTION AFTER RADIATION EXPOSURE

Naunyn-Schmiedeberg's Archives of Pharmacology
2009 | Journal article
WOSUID: WOS:000270185300026
Contributors: Gaugler, M. H.; Ripoche, N.; Gouard, S.; Benderitter, M.; Paris, F.
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P38-MEDIATED ENDOTHELIAL CELL DEATH AFTER IONIZING RADIATION IS UNDER THE CONTROL OF CERAMIDE GENERATION AND MEMBRANE REMODELING

Naunyn-Schmiedeberg's Archives of Pharmacology
2009 | Journal article
WOSUID: WOS:000270185300039
Contributors: Niaudet, C.; Bonnaud, S.; Gouard, S.; Gaugler, M. H.; Corre, I.; Paris, F.
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Pravastatin Limits Radiation-Induced Vascular Dysfunction in the Skin

Journal of Investigative Dermatology
2009 | Journal article
DOI: 10.1038/JID.2008.360
WOSUID: WOS:000266218000028
Contributors: Valerie Holler; Valerie Buard; Marie-Helene Gaugler; Olivier Guipaud; Cedric Baudelin; Amandine Sache; Maria del R. Perez; Claire Squiban; Radia Tamarat; Fabien Milliat et al.
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Radiation effects on circulating and endothelial cell interactions studied by quantitative real-time videomicroscopy.

International Journal of Radiation Biology
2009 | Journal article
DOI: 10.1080/09553000210152980
WOSUID: WOS:000178570800006
Contributors: V. Vereycken-Holler; J. Aigueperse; M.-H. Gaugler
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Membrane-remodeling controls the death of microvascular cells engaged by radiotherapy

European Journal of Cancer, Supplement
2008 | Journal article
DOI: 10.1016/S1359-6349(08)71403-4
WOSUID: WOS:000257919000229
Contributors: Niaudet, C.; Bonnaud, S.; Gouard, S.; Gaugler, M. H.; Corre, I.; Paris, F.
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Intestinal epithelial cell dysfunction is mediated by an endothelial-specific radiation-induced bystander effect

Radiation Research
2007 | Journal article
DOI: 10.1667/RR0702.1
WOSUID: WOS:000243769000006
Contributors: Marie-Hélène Gaugler; Michel Neunlist; Stéphanie Bonnaud; Philippe Aubert; Marc Benderitter; François Paris
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Sphingosine-1-phosphate protects proliferating endothelial cells from ceramide-induced apoptosis but not from DNA damage-induced mitotic death

Cancer Research
2007 | Journal article
DOI: 10.1158/0008-5472.CAN-06-2802
WOSUID: WOS:000244289200049
Contributors: Bonnaud, Stephanie; Niaudet, Colin; Pottier, Geraldine; Gaugler, Marie-Helene; Millour, Julie; Barbet, Jacques; Sabatier, Laure; Paris, Francois
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Application of autologous hematopoietic cell therapy to a nonhuman primate model of heterogeneous high-dose irradiation

Radiation Research
2005 | Journal article
DOI: 10.1667/RR3352
WOSUID: WOS:000228570700011
Contributors: Bertho, JM; Prat, M; Frick, J; Demarquay, C; Gaugler, MH; Dudoignon, N; Clairand, I; Chapel, A; Gorin, NC; Thierry, D et al.
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Pravastatin as a modulator of vascular dysfunction in the cutaneous radiation syndrome

Journal of Investigative Dermatology
2005 | Journal article
WOSUID: WOS:000231862600488
Contributors: Marie-Helene Gaugler
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Pravastatin limits endothelial activation after irradiation and decreases the resulting inflammatory and thrombotic responses

Radiation Research
2005 | Journal article
DOI: 10.1667/RR3302
WOSUID: WOS:000228570700001
Contributors: Gaugler, MH; Vereycken-Holler, V; Squiban, C; Vandamme, M; Vozenin-Brotons, MC; Benderitter, M
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Expression and Function of Integrins on Hematopoietic Progenitor Cells

Acta Haematologica
2004 | Journal article
DOI: 10.1159/000203655
WOSUID: WOS:A1997VY77800004
Contributors: Laure Coulombel; Isabelle Auffray; Marie-Hèlène Gaugler; Mario Rosemblatt
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Parallel-plate flow chamber and intravital microscopy: Two fluorescence analysis tools to quantify platelet interactions with endothelial cells (EC) after irradiation

Cytometry Part A
2004 | Journal article
WOSUID: WOS:000221319900240
Contributors: Marie-Helene Gaugler
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PECAM-1 (CD31) is required for interactions of platelets with endothelial cells after irradiation

Journal of Thrombosis and Haemostasis
2004 | Journal article
DOI: 10.1111/J.1538-7836.2004.00951.X
WOSUID: WOS:000225090700024
Contributors: M.-H. Gaugler; V. Vereycken-Holler; C. Squiban; J. Aigueperse
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Inflammatory reaction and changes in expression of coagulation proteins on lung endothelial cells after total-body irradiation in mice

Radiation Research
2003 | Journal article
DOI: 10.1667/RR3087
WOSUID: WOS:000187079200004
Contributors: Van der Meeren, A; Vandamme, M; Squiban, C; Gaugler, MH; Mouthon, MA
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Irradiation increases the interactions of platelets with the endothelium in vivo: Analysis by intravital microscopy

Radiation Research
2003 | Journal article
DOI: 10.1667/3068
WOSUID: WOS:000186176000013
Contributors: Mouthon, MA; Vereycken-Holler, V; Van der Meeren, A; Gaugler, MH
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Thrombopoietin protects mice from mortality and myelosuppression following high-dose irradiation: importance of time scheduling

Canadian Journal of Physiology and Pharmacology
2002 | Journal article
DOI: 10.1139/Y02-090
WOSUID: WOS:000177331600017
Contributors: Mouthon, MA; Van der Meeren, A; Vandamme, M; Squiban, C; Gaugler, MH
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Ticlopidine inhibits the prothrombotic effects of thrombopoietin and ameliorates survival after supralethal total body irradiation

Thrombosis and Haemostasis
2002 | Journal article
DOI: 10.1055/S-0037-1612993
WOSUID: WOS:000173869300025
Contributors: Mouthon, MA; Gaugler, MH; Vandamme, M; Gourmelon, P; Wagemaker, G; Van der Meeren, A
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Administration of recombinant human IL11 after supralethal radiation exposure promotes survival in mice: interactive effect with thrombopoietin.

Radiation research
2002-06-01 | Journal article
DOI: 10.1667/0033-7587(2002)157[0642:aorhia]2.0.co;2
PMID: 12005542
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Marie-Helene Gaugler

Inflammatory response to abdominal irradiation stimulates hemopoiesis

International Journal of Radiation Biology
2001 | Journal article
DOI: 10.1080/0955300010000782
WOSUID: WOS:000166479900010
Contributors: Mouthon, MA; Vandamme, M; Van der Meeren, A; Gourmelon, P; Gaugler, MH
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Irradiation enhances the support of haemopoietic cell transmigration, proliferation and differentiation by endothelial cells

British Journal of Haematology
2001 | Journal article
DOI: 10.1046/J.1365-2141.2001.02852.X
WOSUID: WOS:000170007900018
Contributors: Gaugler, MH; Squiban, C; Mouthon, MA; Gourmelon, P; Van der Meeren, A
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Single administration of thrombopoietin to lethally irradiated mice prevents infectious and thrombotic events leading to mortality

Experimental Hematology
2001 | Journal article
DOI: 10.1016/S0301-472X(00)00624-X
WOSUID: WOS:000166848000006
Contributors: Mouthon, MA; Gaugler, MH; Van der Meeren, A; Vandamme, M; Gourmelon, P; Wagemaker, G
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Differential regulation by IL-4 and IL-10 of radiation-induced IL-6 and IL-8 production and ICAM-1 expression by human endothelial cells

Cytokine
1999 | Journal article
DOI: 10.1006/CYTO.1999.0497
WOSUID: WOS:000083740200003
Contributors: Van der Meeren, A; Squiban, C; Gourmelon, P; Lafont, H; Gaugler, MH
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Interleukin 4 promotes survival of lethally irradiated mice in the absence of hematopoietic efficacy

Radiation Research
1999 | Journal article
DOI: 10.2307/3580258
WOSUID: WOS:000084168500007
Contributors: Van der Meeren, A; Van der Meeren, A; Gaugler, MH; Gaugler, MH; Mouthon, MA; Mouthon, MA; Squiban, C; Squiban, C; Gourmelon, P; Gourmelon, P
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Thrombopoietin promotes hematopoietic recovery and survival after high-dose whole body irradiation

International Journal of Radiation Oncology Biology Physics
1999 | Journal article
DOI: 10.1016/S0360-3016(98)00477-5
WOSUID: WOS:000079190900021
Contributors: Mouthon, MA; van der Meeren, A; Gaugler, MH; Visser, TP; Squiban, C; Gourmelon, P; Wagemaker, G
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Characterization of the response of human bone marrow endothelial cells to in vitro irradiation

British Journal of Haematology
1998 | Journal article
DOI: 10.1046/J.1365-2141.1998.01119.X
WOSUID: WOS:000077834400012
Contributors: Gaugler, MH; Squiban, C; Claraz, M; Schweitzer, K; Weksler, B; Gourmelon, P; Van der Meeren, A
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Contrasting regulatory mechanism of IL-8 production by endothelial cells in vitro following TNF-alpha stimulation or gamma radiation exposure

The FASEB Journal
1997 | Journal article
WOSUID: WOS:A1997WL53001137
Contributors: VanderMeeren, A; Lafont, H; Vandamme, M; Gaugler, MH
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Ionizing radiation enhances IL-6 and IL-8 production by human endothelial cells

Mediators of Inflammation
1997 | Journal article
DOI: 10.1080/09629359791677
WOSUID: WOS:A1997XP59900003
Contributors: VanderMeeren, A; Bertho, JM; Vandamme, M; Gaugler, MH
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Late and persistent up-regulation of intercellular adhesion molecule-1 (ICAM-1) expression by ionizing radiation in human endothelial cells in vitro

International Journal of Radiation Biology
1997 | Journal article
DOI: 10.1080/095530097143428
WOSUID: WOS:A1997XQ20200009
Contributors: Gaugler, MH; Squiban, C; VanderMeeren, A; Bertho, JM; Vandamme, M; Mouthon, MA
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The radioinduced increased release of soluble adhesion molecules and von Willebrand factor by human endothelial cells is inhibited by a protease inhibitor

Blood
1996 | Journal article
WOSUID: WOS:A1996VT98600214
Contributors: Marie-Helene Gaugler
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Modulation of adhesion molecules expression on stromal cells by ionizing radiation.

Blood
1995 | Journal article
WOSUID: WOS:A1995TH91002645
Contributors: Marie-Helene Gaugler
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RANTES PRODUCTION IS DIFFERENTIALLY REGULATED BY GAMMA-IRRADIATION IN DIFFERENT CELLULAR-MODELS

Molecular Biology of the Cell
1995 | Journal article
WOSUID: WOS:A1995TF51302557
Contributors: Marie-Helene Gaugler
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EXPRESSION OF ADHESION MOLECULES IN HUMAN BONE-MARROW MICROENVIRONMENT AFTER EXPOSURE TO IONIZING-RADIATION IN-VITRO

Experimental Hematology
1994 | Journal article
WOSUID: WOS:A1994PB36800515
Contributors: Marie-Helene Gaugler
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HEMATOPOIETIC GROWTH-FACTORS PRODUCTION BY IRRADIATED HUMAN BONE-MARROW FIBROBLASTS AND UMBILICAL VEIN CORD ENDOTHELIAL-CELLS

Blood
1993 | Journal article
WOSUID: WOS:A1993MJ68202004
Contributors: Marie-Helene Gaugler
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Cell-cell matrix and cell-cell interactions during hematopoietic differentiation

Bone Marrow Transplantation
1992 | Journal article
WOSUID: WOS:A1992JD06400006
Contributors: Coulombel L; Rosemblatt M; Gaugler MH; Leroy C; Vainchenker W
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Adhesive properties of human erythroblastic precursor cells

Blood Cells
1991 | Journal article
WOSUID: WOS:A1991EQ92400006
Contributors: Coulombel L; Vuillet-Gaugler MH; Leroy C; Rosemblatt M; Breton-Gorius J
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ASSOCIATION BETWEEN LEUKEMIC ERYTHROID PROGENITORS AND BONE-MARROW MACROPHAGES

Blood Cells
1991 | Journal article
WOSUID: WOS:A1991EQ92400010
Contributors: BRETONGORIUS, J; VUILLETGAUGLER, MH; COULOMBEL, L; GUICHARD, J; TEILLET, F; VAINCHENKER, W
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