Personal information

Biography

Currently employed as a research associate in a postdoctoral role at the University of Sheffield. The aim of my research is to investigate and improve the treatment for glioblastoma, a disease which generally still has a poor prognosis, using innovate new technology. This is in combination with obtaining and culturing appropriate cell models isolated from patient derived biopsies here in Sheffield.

Previously conducted my PhD research in oncology and chemistry at the University of Sheffield. My work focused on the development of transition metal based drugs to treat superficial cancers.

My skill set

* Cell line derivation from patient derived biopsies

* Tissue culture 2D and 3D (spheroid and 3D scaffolding) with primary and established cell lines

* Bioassays (immunofluorescence, cell viability, molecular detection, cell response pathways, organelle function)

* SDS-PAGE western blot

* Scientific writing

* Combination therapies

* Scoring and data analysis (in vitro and in vivo)

* Bioinformatics

* Microscopy (widefield, confocal, two-photon and TEM)

* Chemical spectroscopy and excited state dynamics

* Nanoparticles (synthesis and translation to cells)

* Protocol development

Activities

Employment (3)

University of Sheffield: Sheffield, GB

Employment
Source: check_circle
myPublications at the University of Sheffield

The University of Sheffield: Sheffield, Sheffield, GB

2021-10-01 to present | Research Associate (Oncology + Metabolism )
Employment
Source: Self-asserted source
Callum Jones

The University of Sheffield: Sheffield, Sheffield, GB

2021-03-01 to 2021-08-31 | Research Assistant (Oncology and Metabolism )
Employment
Source: Self-asserted source
Callum Jones

Education and qualifications (2)

The University of Sheffield: Sheffield, Sheffield, GB

2017-10-01 to 2021-09-30 | Doctor of Philosophy (Oncology + Metabolism )
Education
Source: Self-asserted source
Callum Jones

The University of Sheffield: Sheffield, Sheffield, GB

2013-10-01 to 2017-06-27 | MChem, 1st Class Honours (Chemistry )
Qualification
Source: Self-asserted source
Callum Jones

Funding (1)

Using red light to specifically kill oral tumours

2017-10 to 2020-09 | Grant
Rosetrees Trust (London , GB)
Source: Self-asserted source
Callum Jones

Works (11)

SENP3-FIS1 axis promotes mitophagy and cell survival under hypoxia

Cell Death & Disease
2024-12-05 | Journal article
Contributors: Alice Zhao; Laura Maple; Juwei Jiang; Katie N. Myers; Callum G. Jones; Hannah Gagg; Connor McGarrity-Cottrell; Ola Rominiyi; Spencer J. Collis; Greg Wells et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Ex-vivo models of post-surgical residual disease in human glioblastoma [version 1; peer review: 2 approved with reservations]

2024-11-04 | Journal article
Part of ISSN: 2046-1402
Funded by GRANT_NUMBER:

ET_2019/1_10403, FL_2021_/1_10610

Funded by GRANT_NUMBER: NC/T001895/1
Contributors: Ola Rominiyi; Connor McGarrity-Cottrell; Katie N Myers; Callum G Jones; Kelsey Wosnitzka; Sophie T Williams; Aurelie Vanderlinden; Andra-Gabriela Antohi; Natividad Gomez-Roman; Anthony J Chalmers et al.
Source: check_circle
F1000
grade
Preferred source (of 3)‎

Photostable iridium(III) cyclometallated complex is an efficient photosensitizer for killing multiple cancer cell lines and 3D models under low doses of visible light

Journal of Medicinal Chemistry
2024-09-26 | Journal article
SOURCE-WORK-ID:

1626330

Part of ISSN: 0022-2623
WOSUID:

WOS:001307697100001

Contributors: Callum Jones; M Martinez-Alonso; Hannah Gagg; L Kirby; Julia Weinstein; helen bryant
Source: check_circle
myPublications at the University of Sheffield
grade
Preferred source (of 2)‎

Ex-vivo drug screening of surgically resected glioma stem cells to replace murine avatars and provide personalise cancer therapy for glioblastoma patients [version 2; peer review: 2 approved]

2024-03-11 | Journal article
Part of ISSN: 2046-1402
Funded by GRANT_NUMBER: 200520
Funded by GRANT_NUMBER: ET_2019/1_10403
Funded by GRANT_NUMBER: NC/T002093/1, NC/T001895/1
Funded by GRANT_NUMBER: R6L
Contributors: Hannah Gagg; Sophie T. Williams; Samantha Conroy; Katie N. Myers; Connor McGarrity-Cottrell; Callum Jones; Thomas Helleday; Juha Rantala; Ola Rominiyi; Sarah J. Danson et al.
Source: check_circle
F1000
grade
Preferred source (of 3)‎

Development and Optimisation of Tumour Treating Fields (TTFields) Delivery within 3D Primary Glioma Stem Cell-like Models of Spatial Heterogeneity

Cancers
2024-02-21 | Journal article
Contributors: Callum G. Jones; Aurelie Vanderlinden; Ola Rominiyi; Spencer J. Collis
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

Phototoxicity of cyclometallated Ir(III) complexes bearing a thio-bis-benzimidazole ligand, and its monodentate analogue, as potential PDT photosensitisers in cancer cell killing

JBIC Journal of Biological Inorganic Chemistry
2024-01-06 | Journal article
Contributors: Marta Martínez-Alonso; Callum G. Jones; James D. Shipp; Dimitri Chekulaev; Helen E. Bryant; Julia A. Weinstein
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

DNA damage response inhibitors enhance tumour treating fields (TTFields) potency in glioma stem-like cells

British Journal of Cancer
2023-09-30 | Journal article
Part of ISSN: 0007-0920
Part of ISSN: 1532-1827
Contributors: Aurelie Vanderlinden; Callum G. Jones; Katie N. Myers; Ola Rominiyi; Spencer Collis
Source: Self-asserted source
Callum Jones
grade
Preferred source (of 2)‎

Ex-vivo drug screening of surgically resected glioma stem cells to replace murine avatars and provide personalise cancer therapy for glioblastoma patients

F1000Research
2023-08-08 | Journal article
Contributors: Hannah Gagg; Sophie T. Williams; Samantha Conroy; Katie N. Myers; Connor McGarrity-Cottrell; Callum Jones; Thomas Helleday; Juha Rantala; Ola Rominiyi; Sarah J. Danson et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Heteronuclear d–d and d–f Ru(ii)/M complexes [M = Gd(iii), Yb(iii), Nd(iii), Zn(ii) or Mn(ii)] of ligands combining phenanthroline and aminocarboxylate binding sites: combined relaxivity, cell imaging and photophysical studies

Dalton Transactions
2019 | Journal article
Part of ISSN: 1477-9226
Part of ISSN: 1477-9234
Source: Self-asserted source
Callum Jones
grade
Preferred source (of 3)‎

Photophysical and Cellular Imaging Studies of Brightly Luminescent Osmium(II) Pyridyltriazole Complexes

Inorganic Chemistry
2018-11-05 | Journal article
Part of ISSN: 0020-1669
Part of ISSN: 1520-510X
Source: Self-asserted source
Callum Jones
grade
Preferred source (of 3)‎

Preparation of Substituted Tetrahydro-1-benzazepines by Lithiation-Trapping

European Journal of Organic Chemistry
2018-10-17 | Journal article
Part of ISSN: 1434-193X
Source: Self-asserted source
Callum Jones
grade
Preferred source (of 3)‎