Personal information

Neuron-astrocyte interactions, Astrocyte , Brain development, Cell development, Sonic signaling, Reactive astrogliosis, Cell identity/fate, Microglia, Oligodendrocyte, Progenitor cells, Central Nervous System, Cerebellum, Neurodegenerative Diseases, Synapse formation/pruning, Neuroinflammation, Cell Communication, Phagocytosis, Molecular genetics, Brain injuries, Cell morphogenesis
United States

Activities

Employment (2)

UCSF Medical Center: San Francisco, CA, US

2021-07-01 to present | Specialist (Neurology)
Employment
Source: Self-asserted source
Yajun Xie

Harvard Medical School: Boston, MA, US

2016-09-01 to 2021-06-30 | Postdoc (Neurobiology)
Employment
Source: Self-asserted source
Yajun Xie

Education and qualifications (1)

Zhejiang University: Hangzhou, Zhejiang, CN

2011-09-01 to 2016-06-01 | Ph.D. (Neuroscience)
Qualification
Source: Self-asserted source
Yajun Xie

Funding (2)

Louis Perry Jones Postdoctoral Fellow

Salary award
Harvard Medical School (MA, MA, US)
Source: Self-asserted source
Yajun Xie

The Alice and Joseph Brooks Fund Postdoctoral Fellow

Salary award
Harvard Medical School (MA, MA, US)
Source: Self-asserted source
Yajun Xie

Works (17)

Multimodal classification of neurons in the lateral septum

2024-02-20 | Preprint
Contributors: Christopher M. Reid; Yuqi Ren; Yajun Xie; Miguel Turrero Garcίa; Diana Tran; Steve Vu; Jonathan Liu; Manal A. Adam; Sarah M. Hanson; Angela O. Pisco et al.
Source: check_circle
Crossref

Astrocyte-neuron crosstalk through Hedgehog signaling mediates cortical synapse development

Cell Reports
2022-02 | Journal article
Contributors: Yajun Xie; Aaron T. Kuan; Wengang Wang; Zachary T. Herbert; Olivia Mosto; Olubusola Olukoya; Manal Adam; Steve Vu; Minsu Kim; Diana Tran et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Attraction and repulsion cooperate during brain-circuit wiring

Nature
2021-06-17 | Journal article
Part of ISSN: 0028-0836
Part of ISSN: 1476-4687
Source: Self-asserted source
Yajun Xie
grade
Preferred source (of 2)‎

Gab1 mediates PDGF signaling and is essential to oligodendrocyte differentiation and CNS myelination

eLife
2020 | Journal article
EID:

2-s2.0-85078509963

Part of ISSN: 2050084X
Contributors: Zhou, L.; Shao, C.-Y.; Xie, Y.-J.; Wang, N.; Xu, S.-M.; Luo, B.-Y.; Wu, Z.-Y.; Ke, Y.H.; Qiu, M.; Shen, Y.
Source: Self-asserted source
Yajun Xie via Scopus - Elsevier

Transcriptional regulation of MGE progenitor proliferation by PRDM16 controls cortical GABAergic interneuron production

Development (Cambridge, England)
2020 | Journal article
EID:

2-s2.0-85096347988

Part of ISSN: 14779129
Contributors: Turrero García, M.; Baizabal, J.-M.; Tran, D.N.; Peixoto, R.; Wang, W.; Xie, Y.; Adam, M.A.; English, L.A.; Reid, C.M.; Brito, S.I. et al.
Source: Self-asserted source
Yajun Xie via Scopus - Elsevier

Sonic hedgehog signaling in astrocytes mediates cell type-specific synaptic organization

eLife
2019 | Journal article
EID:

2-s2.0-85069890363

Part of ISSN: 2050084X
Contributors: Hill, S.A.; Blaeser, A.S.; Coley, A.A.; Xie, Y.; Shepard, K.A.; Harwell, C.C.; Gao, W.-J.; Garcia, A.D.R.
Source: Self-asserted source
Yajun Xie via Scopus - Elsevier

Leucine-Rich Glioma Inactivated 1 Promotes Oligodendrocyte Differentiation and Myelination via TSC-mTOR Signaling

Frontiers in Molecular Neuroscience
2018 | Journal article
EID:

2-s2.0-85054850069

Part of ISSN: 16625099
Contributors: Xie, Y.-J.; Zhou, L.; Wang, Y.; Jiang, N.-W.; Cao, S.; Shao, C.-Y.; Wang, X.-T.; Li, X.-Y.; Shen, Y.; Zhou, L.
Source: Self-asserted source
Yajun Xie via Scopus - Elsevier

Celecoxib Ameliorates Seizure Susceptibility in Autosomal Dominant Lateral Temporal Epilepsy

The Journal of Neuroscience
2018-03-28 | Journal article
Contributors: Lin Zhou; Liang Zhou; Li-da Su; Sheng-Long Cao; Ya-Jun Xie; Na Wang; Chong-Yu Shao; Ya-Nan Wang; Jia-Huan Zhou; John K. Cowell et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Downregulation of Glutamate Transporter EAAT4 by Conditional Knockout of Rheb1 in Cerebellar Purkinje Cells

Cerebellum
2016 | Journal article
EID:

2-s2.0-84937604330

Part of ISSN: 14734230 14734222
Contributors: Jiang, N.-W.; Wang, D.-J.; Xie, Y.-J.; Zhou, L.; Su, L.-D.; Li, H.; Wang, Q.-W.; Shen, Y.
Source: Self-asserted source
Yajun Xie via Scopus - Elsevier

Essential roles of leucine-rich glioma inactivated 1 in the development of embryonic and postnatal cerebellum

Scientific Reports
2015 | Journal article
EID:

2-s2.0-84929350648

Part of ISSN: 20452322
Contributors: Xie, Y.-J.; Zhou, L.; Jiang, N.; Zhang, N.; Zou, N.; Zhou, L.; Wang, Y.; Cowell, J.K.; Shen, Y.
Source: Self-asserted source
Yajun Xie via Scopus - Elsevier

LGI1 is Involved in the Development of Mouse Brain

Cerebellum
2015 | Journal article
EID:

2-s2.0-84925484003

Part of ISSN: 14734230 14734222
Contributors: Su, L.-D.; Xie, Y.-J.; Zhou, L.; Shen, Y.; Hu, Y.-H.
Source: Self-asserted source
Yajun Xie via Scopus - Elsevier

Numb deficiency in cerebellar Purkinje cells impairs synaptic expression of metabotropic glutamate receptor and motor coordination

Proceedings of the National Academy of Sciences of the United States of America
2015 | Journal article
EID:

2-s2.0-84950335863

Part of ISSN: 10916490 00278424
Contributors: Zhou, L.; Yang, D.; Wang, D.-J.; Xie, Y.-J.; Zhou, J.-H.; Zhou, L.; Huang, H.; Han, S.; Shao, C.-Y.; Li, H.-S. et al.
Source: Self-asserted source
Yajun Xie via Scopus - Elsevier

GSK3β Promotes the Differentiation of Oligodendrocyte Precursor Cells via β-Catenin-Mediated Transcriptional Regulation

Molecular Neurobiology
2014 | Journal article
EID:

2-s2.0-84911007211

Part of ISSN: 15591182 08937648
Contributors: Zhou, L.; Shao, C.-Y.; Xu, S.-M.; Ma, J.; Xie, Y.-J.; Zhou, L.; Teng, P.; Wang, Y.; Qiu, M.; Shen, Y.
Source: Self-asserted source
Yajun Xie via Scopus - Elsevier

C-terminal domain of ICA69 interacts with PICK1 and acts on trafficking of PICK1-PKCα complex and cerebellar plasticity

PLoS ONE
2013 | Journal article
EID:

2-s2.0-84892667812

Part of ISSN: 19326203
Contributors: Wang, Z.; Wang, Y.-N.; Sun, C.-L.; Yang, D.; Su, L.-D.; Xie, Y.-J.; Zhou, L.; Wang, Y.; Shen, Y.
Source: Self-asserted source
Yajun Xie via Scopus - Elsevier

Distinct Functions of Nuclear Distribution Proteins LIS1, Ndel1 and NudCL in Regulating Axonal Mitochondrial Transport

Traffic
2013 | Journal article
EID:

2-s2.0-84878991033

Part of ISSN: 13989219 16000854
Contributors: Shao, C..-Y.; Zhu, J.; Xie, Y..-J.; Wang, Z.; Wang, Y..-N.; Wang, Y.; Su, L..-D.; Zhou, L.; Zhou, T..-H.; Shen, Y.
Source: Self-asserted source
Yajun Xie via Scopus - Elsevier

Upregulation of glutamate transporter GLT-1 by mTOR-Akt-NF-kB cascade in astrocytic oxygen-glucose deprivation

GLIA
2013 | Journal article
EID:

2-s2.0-84886640630

Part of ISSN: 08941491 10981136
Contributors: Ji, Y.-F.; Zhou, L.; Xie, Y.-J.; Xu, S.-M.; Zhu, J.; Teng, P.; Shao, C.-Y.; Wang, Y.; Luo, J.-H.; Shen, Y.
Source: Self-asserted source
Yajun Xie via Scopus - Elsevier

Cytosolic phospholipase A <inf>2</inf> alpha/arachidonic acid signaling mediates depolarization-induced suppression of excitation in the cerebellum

PLoS ONE
2012 | Journal article
EID:

2-s2.0-84865161325

Part of ISSN: 19326203
Contributors: Wang, D.-J.; Yang, D.; Su, L.-D.; Xie, Y.-j.; Zhou, L.; Sun, C.-L.; Wang, Y.; Wang, X.-X.; Zhou, L.; Shen, Y.
Source: Self-asserted source
Yajun Xie via Scopus - Elsevier

Peer review (10 reviews for 5 publications/grants)

Review activity for Biology. (5)
Review activity for Biomolecules. (1)
Review activity for International journal of molecular sciences. (1)
Review activity for Life. (1)
Review activity for NeuroSci. (2)