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Biography

Dr. Kenji Mizuguchi is Professor of Computational Biology at Institute for Protein Research, Osaka University.

His research focuses on the development of computational methods for predicting protein structure, function and interaction, as well as data integration and database development, all aiming to establish systems approaches to drug discovery. His contributions to data integration include TargertMine, an integrated data warehouse for target prioritization, and DruMAP (Drug Metabolism and pharmacokinetics Analysis Platform), which is also a basis for a collaborative data sharing program with a group of pharmaceutical companies. He has applied original predictive methods, such as FUGUE for protein structures and PSIVER for protein interaction sites, to real-life projects, and succeeded in validating potential targets and designing novel drug candidate molecules.

He was previously Director of Artificial Intelligence Center for Health and Medical Research (ArCHER), at National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Japan (2019-2024), a Research Group Head at NIBIOHN (2006-2024), a University Lecturer at the Department of Applied Mathematics and Theoretical Physics (2004-2006) and a Group Leader at the Department of Biochemistry, University of Cambridge (2000-2004).

Prior to that, he was a postdoctoral fellow at Birkbeck College, University of London and at University of Cambridge (as a Long-Term Fellow of the Human Frontier Science Programme and a Fellow of the Japan Society for the Promotion of Science for Young Scientists).

Activities

Employment (1)

Osaka University: Suita, JP

(Institute for Protein Research)
Employment
Source: Self-asserted source
Kenji Mizuguchi

Funding (9)

Improved identification of drug targets by data warehousing and simulations of signal transduction pathways

Source: Self-asserted source
Kenji Mizuguchi via DimensionsWizard

Development of a target discovery platform by integrating data warehousing and protein function prediction

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Kenji Mizuguchi via DimensionsWizard

Drug development and biological function study of novel estrogen receptor activity modulator BIG3 protein

Source: Self-asserted source
Kenji Mizuguchi via DimensionsWizard

疾患関連タンパク質における機能決定アミノ酸残基の予測

Source: Self-asserted source
Kenji Mizuguchi via DimensionsWizard

Development and Expansion of the FlyMine/InterMine Project. No-cost extension of 8 months beyond original extension. Original end date 31/03/09. SA.

An integrated database for Drosophila and Anopheles genomics.

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Kenji Mizuguchi via DimensionsWizard

An integrated database for Drosophila and Anopheles genomics.

Source: Self-asserted source
Kenji Mizuguchi via DimensionsWizard

Prediction of structure and function for the Drosphila genome sequences. (Supplement to original award)

Source: Self-asserted source
Kenji Mizuguchi via DimensionsWizard

Prediction of structure and function for the Drosphila genome sequences.

Source: Self-asserted source
Kenji Mizuguchi via DimensionsWizard