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Japan

Activities

Employment (1)

Shionogi & Co., Ltd: Osaka, JP

2005-04-01 to present | Research Director (Biopharmaceutical analysis)
Employment
Source: Self-asserted source
Hiroshi Ueda

Education and qualifications (3)

Osaka University: Osaka, JP

2024-04-01 to present | MPH (Public Health)
Education
Source: Self-asserted source
Hiroshi Ueda

Kobe University: Kobe, JP

2021-04-01 to 2022-09-25 | MBA (Business administration)
Education
Source: Self-asserted source
Hiroshi Ueda

Osaka University of Pharmaceutical Sciences: Takatsuki, JP

2012-04-01 to 2015-03-31 | Ph.D (Pharmaceutical Science)
Qualification
Source: Self-asserted source
Hiroshi Ueda

Professional activities (1)

University of Copenhagen: Copenhagen, DK

2016-04-01 to 2017-03-01 | Guest Post Doctoral Researcher (Department of Pharmacy)
Invited position
Source: Self-asserted source
Hiroshi Ueda

Works (30)

Formation of drug–drug salt crystals and co-amorphous forms of levofloxacin and 4-aminosalicylic acid for pulmonary applications

RSC Pharmaceutics
2025 | Journal article
Contributors: Hiroshi Ueda; Jun Yee Tse; Tetsuya Miyano; Yuzuki Nakayama; Peiwen Mo; Yuta Hatanaka; Hiromasa Uchiyama; Yuichi Tozuka; Kazunori Kadota
Source: check_circle
Crossref

Specific intermolecular interaction with sodium glycocholate generates the co-amorphous system showing higher physical stability and aqueous solubility of Y<sub>5</sub> receptor antagonist of neuropeptide Y, a brick dust molecule

European Journal of Pharmaceutics and Biopharmaceutics
2024 | Journal article
EID:

2-s2.0-85199257213

Part of ISSN: 18733441 09396411
Contributors: Aikawa, S.; Tanaka, H.; Ueda, H.; Maruyama, M.; Higaki, K.
Source: Self-asserted source
Hiroshi Ueda via Scopus - Elsevier
grade
Preferred source (of 2)‎

Cocrystallization Enables Ensitrelvir to Overcome Anomalous Low Solubility Caused by Strong Intermolecular Interactions between Triazine–Triazole Groups in Stable Crystal Form

Molecular Pharmaceutics
2024-12-02 | Journal article
Contributors: Tetsuya Miyano; Shigeru Ando; Daiki Nagamatsu; Yui Watanabe; Daichi Sawada; Hiroshi Ueda
Source: check_circle
Crossref

Co-Amorphous Solid Dispersion System for Improvement in Dissolution Profile of N-(((1r,4r)-4-((6-fluorobenzo[d]oxazol-2-yl)amino)cyclohexyl)methyl)-2-methylpropane-2-sulfonamide as a Neuropeptide Y5 Receptor Antagonist

Pharmaceutics
2024-10-02 | Journal article
Contributors: Hironori Tanaka; Hiroshi Ueda
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

The Continuous and Reversible Transformation of the Polymorphs of an MGAT2 Inhibitor (S-309309) from the Anhydrate to the Hydrate in Response to Relative Humidity

Pharmaceutics
2024-07-17 | Journal article
Contributors: Tetsuya Miyano; Katsuji Sugita; Hiroshi Ueda
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

Continuous and reversible transformation of the polymorphs of an MGAT2 inhibitor (S-309309) from the anhydrate to the hydrate in response to relative humidity

2024-06-20 | Preprint
Contributors: Hiroshi Ueda; Katsuji Sugita; Tetsuya Miyano
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Baloxavir Marboxil Shows Anomalous Conversion of Crystal Forms from Stable to Metastable through Formation of Specific Solvate Form

Journal of Pharmaceutical Sciences
2023 | Journal article
EID:

2-s2.0-85134837600

Part of ISSN: 15206017 00223549
Contributors: Ueda, H.; Osaki, H.; Miyano, T.
Source: Self-asserted source
Hiroshi Ueda via Scopus - Elsevier
grade
Preferred source (of 2)‎

COVID-19 Induces Innovation of Drug Discovery and Development,新型コロナウイルス感染症がもたらした医薬品の研究開発の変革

Journal of the Society of Powder Technology, Japan
2023 | Journal article
EID:

2-s2.0-85165187228

Part of ISSN: 18837239 03866157
Contributors: Ueda, H.
Source: Self-asserted source
Hiroshi Ueda via Scopus - Elsevier

Dissolution-permeation of hot-melt extruded amorphous solid dispersion comprising an experimental grade of HPMCAS

ADMET and DMPK
2023 | Journal article
EID:

2-s2.0-85174688091

Part of ISSN: 18487718
Contributors: Tanaka, H.; Miyano, T.; Ueda, H.
Source: Self-asserted source
Hiroshi Ueda via Scopus - Elsevier
grade
Preferred source (of 2)‎

Formation of a Stable Co-Amorphous System for a Brick Dust Molecule by Utilizing Sodium Taurocholate with High Glass Transition Temperature

Pharmaceutics
2023 | Journal article
EID:

2-s2.0-85146572949

Part of ISSN: 19994923
Contributors: Aikawa, S.; Tanaka, H.; Ueda, H.; Maruyama, M.; Higaki, K.
Source: Self-asserted source
Hiroshi Ueda via Scopus - Elsevier
grade
Preferred source (of 3)‎

Formation of Hemihydrate Crystal form Overcomes Milling Issue Induced by Exposed Functional Groups on Cleavage Plane for a Y5 Receptor Antagonist of Neuropeptide Y

Journal of Pharmaceutical Sciences
2023 | Journal article
EID:

2-s2.0-85158886146

Part of ISSN: 15206017 00223549
Contributors: Nagamatsu, D.; Ando, S.; Fujimura, Y.; Miyano, T.; Sugita, K.; Ueda, H.
Source: Self-asserted source
Hiroshi Ueda via Scopus - Elsevier
grade
Preferred source (of 2)‎

Improvement in Inhalation Properties of Theophylline and Levofloxacin by Co-Amorphization and Enhancement in Its Stability by Addition of Amino Acid as a Third Component

Molecular Pharmaceutics
2023 | Journal article
EID:

2-s2.0-85178107627

Part of ISSN: 15438392 15438384
Contributors: Ueda, H.; Hirakawa, Y.; Miyano, T.; Nakayama, Y.; Hatanaka, Y.; Uchiyama, H.; Tozuka, Y.; Kadota, K.
Source: Self-asserted source
Hiroshi Ueda via Scopus - Elsevier
grade
Preferred source (of 2)‎

Microelectron Diffraction Reveals Contamination of Polymorphs by Structure Analysis of Microscale Crystals in a Novel Pharmaceutical Cocrystal

Crystal Growth and Design
2023 | Journal article
EID:

2-s2.0-85176127673

Part of ISSN: 15287505 15287483
Contributors: Miyano, T.; Hirakawa, Y.; Yamano, A.; Ueda, H.
Source: Self-asserted source
Hiroshi Ueda via Scopus - Elsevier
grade
Preferred source (of 2)‎

Design of a Stable Coamorphous System Using Lactose as an Antiplasticizing Agent for Diphenhydramine Hydrochloride with a Low Glass Transition Temperature

Molecular Pharmaceutics
2022-03-22 | Journal article
Part of ISSN: 1543-8384
Part of ISSN: 1543-8392
Source: Self-asserted source
Hiroshi Ueda
grade
Preferred source (of 3)‎

Applicability of an experimental grade of hydroxypropyl methylcellulose acetate succinate as a carrier for formation of solid dispersion with indomethacin

Pharmaceutics
2021 | Journal article
EID:

2-s2.0-85102860263

Part of ISSN: 19994923
Contributors: Ueda, H.; Hirakawa, Y.; Tanaka, H.; Miyano, T.; Sugita, K.
Source: Self-asserted source
Hiroshi Ueda via Scopus - Elsevier
grade
Preferred source (of 3)‎

Co-amorphous formation of piroxicam-citric acid to generate supersaturation and improve skin permeation

European Journal of Pharmaceutical Sciences
2021 | Journal article
EID:

2-s2.0-85097756315

Part of ISSN: 18790720 09280987
Contributors: Hirakawa, Y.; Ueda, H.; Takata, Y.; Minamihata, K.; Wakabayashi, R.; Kamiya, N.; Goto, M.
Source: Self-asserted source
Hiroshi Ueda via Scopus - Elsevier

Multiwell Raman plate reader for high-throughput biochemical screening

Scientific Reports
2021-12 | Journal article
Part of ISSN: 2045-2322
Source: Self-asserted source
Hiroshi Ueda
grade
Preferred source (of 2)‎

A novel binary supercooled liquid formulation for transdermal drug delivery

Biological and Pharmaceutical Bulletin
2020 | Journal article
EID:

2-s2.0-85081070683

Part of ISSN: 13475215 09186158
Contributors: Hirakawa, Y.; Ueda, H.; Wakabayashi, R.; Kamiya, N.; Goto, M.
Source: Self-asserted source
Hiroshi Ueda via Scopus - Elsevier

Formulation of co-amorphous systems from naproxen and naproxen sodium and in situ monitoring of physicochemical state changes during dissolution testing by Raman spectroscopy

International Journal of Pharmaceutics
2020 | Journal article
EID:

2-s2.0-85088100862

Part of ISSN: 18733476 03785173
Contributors: Ueda, H.; Peter Bøtker, J.; Edinger, M.; Löbmann, K.; Grohganz, H.; Müllertz, A.; Rades, T.; Østergaard, J.
Source: Self-asserted source
Hiroshi Ueda via Scopus - Elsevier

In-situ dissolution and permeation studies of nanocrystal formulations with second-derivative UV spectroscopy

International Journal of Pharmaceutics
2019 | Journal article
EID:

2-s2.0-85060247742

Part of ISSN: 18733476 03785173
Contributors: Imono, M.; Uchiyama, H.; Ueda, H.; Kadota, K.; Tozuka, Y.
Source: Self-asserted source
Hiroshi Ueda via Scopus - Elsevier

New insight into transdermal drug delivery with supersaturated formulation based on co-amorphous system

International Journal of Pharmaceutics
2019 | Journal article
EID:

2-s2.0-85070557301

Part of ISSN: 18733476 03785173
Contributors: Hirakawa, Y.; Ueda, H.; Miyano, T.; Kamiya, N.; Goto, M.
Source: Self-asserted source
Hiroshi Ueda via Scopus - Elsevier

Application of a Salt Coformer in a Co-Amorphous Drug System Dramatically Enhances the Glass Transition Temperature: A Case Study of the Ternary System Carbamazepine, Citric Acid, and l -Arginine

Molecular Pharmaceutics
2018 | Journal article
EID:

2-s2.0-85046644032

Part of ISSN: 15438392 15438384
Contributors: Ueda, H.; Wu, W.; Löbmann, K.; Grohganz, H.; Müllertz, A.; Rades, T.
Source: Self-asserted source
Hiroshi Ueda via Scopus - Elsevier

Organic acids as co-formers for co-amorphous systems – Influence of variation in molar ratio on the physicochemical properties of the co-amorphous systems

European Journal of Pharmaceutics and Biopharmaceutics
2018 | Journal article
EID:

2-s2.0-85050334408

Part of ISSN: 18733441 09396411
Contributors: Wu, W.; Ueda, H.; Löbmann, K.; Rades, T.; Grohganz, H.
Source: Self-asserted source
Hiroshi Ueda via Scopus - Elsevier

Co-amorphous Formation Induced by Combination of Tranilast and Diphenhydramine Hydrochloride

Journal of Pharmaceutical Sciences
2017 | Journal article
EID:

2-s2.0-84993988081

Part of ISSN: 15206017 00223549
Contributors: Ueda, H.; Kadota, K.; Imono, M.; Ito, T.; Kunita, A.; Tozuka, Y.
Source: Self-asserted source
Hiroshi Ueda via Scopus - Elsevier

A Strategy for Co-former Selection to Design Stable Co-amorphous Formations Based on Physicochemical Properties of Non-steroidal Inflammatory Drugs

Pharmaceutical Research
2016 | Journal article
EID:

2-s2.0-84960447982

Part of ISSN: 1573904X 07248741
Contributors: Ueda, H.; Muranushi, N.; Sakuma, S.; Ida, Y.; Endoh, T.; Kadota, K.; Tozuka, Y.
Source: Self-asserted source
Hiroshi Ueda via Scopus - Elsevier

Low hygroscopic spray-dried powders with trans-glycosylated food additives enhance the solubility and oral bioavailability of ipriflavone

Food Chemistry
2016 | Journal article
EID:

2-s2.0-84933074132

Part of ISSN: 18737072 03088146
Contributors: Fujimori, M.; Kadota, K.; Kato, K.; Seto, Y.; Onoue, S.; Sato, H.; Ueda, H.; Tozuka, Y.
Source: Self-asserted source
Hiroshi Ueda via Scopus - Elsevier

Anomalous role change of tertiary amino and ester groups as hydrogen acceptors in eudragit E based solid dispersion depending on the concentration of naproxen

Molecular Pharmaceutics
2015 | Journal article
EID:

2-s2.0-84926617518

Part of ISSN: 15438392 15438384
Contributors: Ueda, H.; Wakabayashi, S.; Kikuchi, J.; Ida, Y.; Kadota, K.; Tozuka, Y.
Source: Self-asserted source
Hiroshi Ueda via Scopus - Elsevier

Anti-plasticizing effect of amorphous indomethacin induced by specific intermolecular interactions with PVA copolymer

Journal of Pharmaceutical Sciences
2014 | Journal article
EID:

2-s2.0-84906316321

Part of ISSN: 15206017 00223549
Contributors: Ueda, H.; Aikawa, S.; Kashima, Y.; Kikuchi, J.; Ida, Y.; Tanino, T.; Kadota, K.; Tozuka, Y.
Source: Self-asserted source
Hiroshi Ueda via Scopus - Elsevier

Raman mapping for kinetic analysis of crystallization of amorphous drug based on distributional images

International Journal of Pharmaceutics
2014 | Journal article
EID:

2-s2.0-84892618704

Part of ISSN: 03785173 18733476
Contributors: Ueda, H.; Ida, Y.; Kadota, K.; Tozuka, Y.
Source: Self-asserted source
Hiroshi Ueda via Scopus - Elsevier

Process monitoring of ultrasound compaction as a small-scale heating process

European Journal of Pharmaceutical Sciences
2013 | Journal article
EID:

2-s2.0-84885082640

Part of ISSN: 18790720 09280987
Contributors: Ueda, H.; Kawai, A.; Hayashi, T.; Ida, Y.; Kakemi, M.; Tozuka, Y.
Source: Self-asserted source
Hiroshi Ueda via Scopus - Elsevier

Peer review (16 reviews for 8 publications/grants)

Review activity for ACS omega. (1)
Review activity for Crystal growth & design. (2)
Review activity for European journal of pharmaceutical sciences. (2)
Review activity for European journal of pharmaceutics and biopharmaceutics. (5)
Review activity for Journal of pharmaceutical & biomedical analysis. (1)
Review activity for Journal of pharmaceutical sciences : (2)
Review activity for Powder technology. (2)
Review activity for The journal of physical chemistry. (1)