Personal information

Other IDs

Scopus Author ID: 8730245600

Keywords

Stroke, MRI, cerebral blood flow,

Countries

United Kingdom

Activities

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Employment (3)

UCB Pharma (United Kingdom): Slough, England, GB

2018-09-03 to present | Medical Science Liaison (Immunology)
Employment
Source: Self-asserted source
Chris McCabe

University of Glasgow: Glasgow, Glasgow, GB

2006-11-01 to 2018-08-31 | Research Fellow (Principal Investigator; SFC funded) (Institute of Neuroscience & Psychology)
Employment
Source: Self-asserted source
Chris McCabe

University of Glasgow: Glasgow, Glasgow, GB

2003-06-01 to 2006-10-31 | Postdoctoral Research Associate (Division of Clinical Neuroscience)
Employment
Source: Self-asserted source
Chris McCabe

Education and qualifications (3)

University of Glasgow: Glasgow, Glasgow, GB

2014-10-01 to 2017-06-01 | Postgraduate Certificate in Academic Practice
Education
Source: Self-asserted source
Chris McCabe

University of Strathclyde: Glasgow, Glasgow, GB

2000-06-01 to 2003-06-01 | PhD Cardiovascular Pharmacology (Physiology & Pharmacology)
Education
Source: Self-asserted source
Chris McCabe

University of Strathclyde: Glasgow, Glasgow, GB

1995-10-01 to 1999-06-01 | BSc (Hons) Immunology & Pharmacology (Physiology & Pharmacology)
Education
Source: Self-asserted source
Chris McCabe

Professional activities (1)

Journal of Cerebral Blood Flow & Metabolism: Glasgow, GB

2017-01-02 to 2018-08-31 | Editorial Board member
Invited position
Source: Self-asserted source
Chris McCabe

Funding (9)

Memantine – developing a prophylactic treatment for ischemic stroke

2016-03 to 2018-03 | Grant
Henry Smith Charity (London, GB)
Source: Self-asserted source
Chris McCabe

Brain damage after stroke: role of Angiotensin-1-7.

2014-10 to 2016-09 | Grant
Henry Smith Charity (London, GB)
Source: Self-asserted source
Chris McCabe

Supporting the ischaemic brain with oxygen-carrying perfluorocarbons.

2011 to 2013 | Grant
Chief Scientist Office (Edinburgh, GB)
Source: Self-asserted source
Chris McCabe

Inhibition of NADPH Oxidase as a potential neuroprotective strategy in the Stroke Prone Spontaneously Hypertensive (SHRSP) rat.

2010 to 2011 | Grant
Neurosciences foundation (Glasgow, GB)
Source: Self-asserted source
Chris McCabe

Metabolic syndrome, acute hyperglycemia and ischaemic lesion growth after experimentally-induced stroke.

2009 to 2010 | Contract
Chief Scientist Office (Edinburgh, GB)
Source: Self-asserted source
Chris McCabe

Imaging the Ischaemic Penumbra using BOLD MRI with oxygen challenge as a metabolic biotracer

2008-03-10 to 2011-03-09 | Grant
Medical Research Council (Swindon, GB)
GRANT_NUMBER: G0700439
GRANT_NUMBER: G0700439
Source: Self-asserted source
Chris McCabe via DimensionsWizard
grade
Preferred source (of 2)‎

Development of techniques and animal models to study the ischaemic penumbra in stroke.

2008 to 2009 | Grant
Wyeth TMRC research grant (Dundee, GB)
Source: Self-asserted source
Chris McCabe

Characterising the ischaemic penumbra in the SHRSP and WKY following focal cerebral ischaemia.

2006 to 2007 | Grant
Neurosciences Foundation (Glasgow, GB)
Source: Self-asserted source
Chris McCabe

The role of GADD34 in cerebral ischaemia: an investigation of focal ischaemia in GADD34 knockout mice.

2005 to 2006 | Grant
Neurosciences Foundation (Glasgow, GB)
Source: Self-asserted source
Chris McCabe

Works (43)

Impact of stroke co-morbidities on cortical collateral flow following ischaemic stroke

Journal of Cerebral Blood Flow and Metabolism
2020 | Journal article
DOI: 10.1177/0271678X19858532
EID:

2-s2.0-85068217552

Part of ISSN: 15597016 0271678X
Contributors: Biose, I.J.; Dewar, D.; Macrae, I.M.; McCabe, C.
Source: Self-asserted source
Chris McCabe via Scopus - Elsevier

UK consensus on pre-clinical vascular cognitive impairment functional outcomes assessment: Questionnaire and workshop proceedings

Journal of Cerebral Blood Flow & Metabolism
2020-07 | Journal article
DOI: 10.1177/0271678x20910552
Part of ISSN: 0271-678X
Part of ISSN: 1559-7016
Source: Self-asserted source
Chris McCabe
grade
Preferred source (of 2)‎

Change in CSF Dynamics Responsible for ICP Elevation After Ischemic Stroke in Rats: a New Mechanism for Unexplained END?

2019-08-15 | Journal article
DOI: 10.1007/s12975-019-00719-6
Source: Self-asserted source
Chris McCabe
grade
Preferred source (of 2)‎

Impact of stroke co-morbidities on cortical collateral flow following ischaemic stroke.

2019-06-01 | Journal article
PMID: 31234703
Source: Self-asserted source
Chris McCabe

Assessing the effects of Ang-(1-7) therapy following transient middle cerebral artery occlusion

Scientific Reports
2019-02-28 | Journal article
DOI: 10.1038/s41598-019-39102-8
Contributors: M. M. C. Arroja; E. Reid; L. A. Roy; A. V. Vallatos; W. M. Holmes; S. A. Nicklin; L. M. Work; C. McCabe
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Altered Extracellular Vesicle MicroRNA Expression in Ischemic Stroke and Small Vessel Disease.

Translational stroke research
2019-01 | Journal article
DOI: 10.1007/s12975-018-0682-3
PMID: 30617992
Contributors: van Kralingen JC; McFall A; Ord ENJ; Coyle TF; Bissett M; McClure JD; McCabe C; Macrae IM; Dawson J; Work LM
Source: Self-asserted source
Chris McCabe via Europe PubMed Central
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Preclinical Validation of the Therapeutic Potential of Glasgow Oxygen Level Dependent (GOLD) Technology: a Theranostic for Acute Stroke.

Translational stroke research
2018-11 | Journal article
DOI: 10.1007/s12975-018-0679-y
PMID: 30506268
Contributors: Deuchar GA; van Kralingen JC; Work LM; Santosh C; Muir KW; McCabe C; Macrae IM
Source: Self-asserted source
Chris McCabe via Europe PubMed Central
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Variability of functional outcome measures used in animal models of stroke and vascular cognitive impairment – a review of contemporary studies

Journal of Cerebral Blood Flow & Metabolism
2018-11 | Journal article
DOI: 10.1177/0271678X18799858
Contributors: Tuuli M Hietamies; Caroline Ostrowski; Zhong Pei; Luyang Feng; Christopher McCabe; Lorraine M Work; Terence J Quinn
Source: check_circle
Crossref
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Animal models of ischaemic stroke and characterisation of the ischaemic penumbra

Neuropharmacology
2018-05 | Journal article
DOI: 10.1016/j.neuropharm.2017.09.022
Contributors: Christopher McCabe; Mariana M. Arroja; Emma Reid; I. Mhairi Macrae
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Crossref
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Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology.

Clinical science (London, England : 1979)
2018-04 | Journal article
DOI: 10.1042/cs20171620
PMID: 29712883
Contributors: Horsburgh K; Wardlaw JM; van Agtmael T; Allan SM; Ashford MLJ; Bath PM; Brown R; Berwick J; Cader MZ; Carare RO et al.
Source: Self-asserted source
Chris McCabe via Europe PubMed Central
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Chronic photoperiod disruption does not increase vulnerability to focal cerebral ischemia in young normotensive rats

Journal of Cerebral Blood Flow and Metabolism
2017 | Journal article
DOI: 10.1177/0271678X16671316
EID:

2-s2.0-85032721905

Part of ISSN: 15597016 0271678X
Contributors: Ku Mohd Noor, K.M.; Wyse, C.; Roy, L.A.; Biello, S.M.; McCabe, C.; Dewar, D.
Source: Self-asserted source
Chris McCabe via Scopus - Elsevier

The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments).

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
2017-08 | Journal article
DOI: 10.1177/0271678X17709185
PMID: 28797196
PMC: PMC5669349
Contributors: Percie du Sert N; Alfieri A; Allan SM; Carswell HV; Deuchar GA; Farr TD; Flecknell P; Gallagher L; Gibson CL; Haley MJ et al.
Source: Self-asserted source
Chris McCabe via Europe PubMed Central
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Therapeutic potential of the renin angiotensin system in ischaemic stroke

Experimental & Translational Stroke Medicine
2016-12 | Journal article
DOI: 10.1186/s13231-016-0022-1
Contributors: Mariana Moreira Coutinho Arroja; Emma Reid; Christopher McCabe
Source: check_circle
Crossref
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Chronic photoperiod disruption does not increase vulnerability to focal cerebral ischemia in young normotensive rats.

2016-10 | Journal article
PMID: 27789784
Contributors: Ku Mohd Noor KM; Wyse C; Roy LA; Biello SM; McCabe C; Dewar D
Source: Self-asserted source
Chris McCabe via Europe PubMed Central

Imaging the ischaemic penumbra with T2* weighted MRI.

2016-02 | Journal article
DOI: 10.1177/0271678X15606464
PMID: 26661167
Contributors: McCabe C
Source: Self-asserted source
Chris McCabe via Europe PubMed Central
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The influence of gender on 'tissue at risk' in acute stroke: A diffusion-weighted magnetic resonance imaging study in a rat model of focal cerebral ischaemia.

2016-02 | Journal article
DOI: 10.1177/0271678X15606137
PMID: 26661149
Contributors: Baskerville TA; Macrae IM; Holmes WM; McCabe C
Source: Self-asserted source
Chris McCabe via Europe PubMed Central
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Erratum: Intracranial pressure elevation after ischemic stroke in rats: Cerebral edema is not the only cause, and short-duration mild hypothermia is a highly effective preventive therapy (Journal of Cerebral Blood Flow & Metabolism (2015) 35 (592-600) DOI: 10.1038/jcbfm.2014.230)

Journal of Cerebral Blood Flow and Metabolism
2015 | Journal article
DOI: 10.1038/jcbfm.2015.209
EID:

2-s2.0-84948673524

Part of ISSN: 15597016 0271678X
Contributors: Murtha, L.A.; Mcleod, D.D.; Pepperall, D.; Mccann, S.K.; Beard, D.J.; Tomkins, A.J.; Holmes, W.M.; Mccabe, C.; Macrae, I.M.; Spratt, N.J.
Source: Self-asserted source
Chris McCabe via Scopus - Elsevier

Intracranial pressure elevation after ischemic stroke in rats: cerebral edema is not the only cause, and short-duration mild hypothermia is a highly effective preventive therapy.

2015-04 | Journal article
DOI: 10.1038/jcbfm.2014.230
PMID: 25515213
Contributors: Murtha LA; McLeod DD; Pepperall D; McCann SK; Beard DJ; Tomkins AJ; Holmes WM; McCabe C; Macrae IM; Spratt NJ
Source: Self-asserted source
Chris McCabe via Europe PubMed Central
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Detection of ischemic penumbra using combined perfusion and T2* oxygen challenge imaging.

2015-01 | Journal article
DOI: 10.1111/ijs.12327
PMID: 25042078
PMC: PMC4283703
Contributors: Robertson CA; McCabe C; Lopez-Gonzalez MR; Deuchar GA; Dani K; Holmes WM; Muir KW; Santosh C; Macrae IM
Source: Self-asserted source
Chris McCabe via Europe PubMed Central
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Sodium-23 magnetic resonance imaging has potential for improving penumbra detection but not for estimating stroke onset time.

2015-01 | Journal article
DOI: 10.1038/jcbfm.2014.174
PMID: 25335803
Contributors: Wetterling F; Gallagher L; Mullin J; Holmes WM; McCabe C; Macrae IM; Fagan AJ
Source: Self-asserted source
Chris McCabe via Europe PubMed Central
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Hyperglycemia accelerates apparent diffusion coefficient-defined lesion growth after focal cerebral ischemia in rats with and without features of metabolic syndrome.

2013-10 | Journal article
DOI: 10.1038/jcbfm.2013.107
PMID: 23838826
PMC: PMC3790923
Contributors: Tarr D; Graham D; Roy LA; Holmes WM; McCabe C; Mhairi Macrae I; Muir KW; Dewar D
Source: Self-asserted source
Chris McCabe via Europe PubMed Central
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Combined antiapoptotic and antioxidant approach to acute neuroprotection for stroke in hypertensive rats.

2013-08 | Journal article
DOI: 10.1038/jcbfm.2013.70
PMID: 23632970
PMC: PMC3734772
Contributors: Ord EN; Shirley R; McClure JD; McCabe C; Kremer EJ; Macrae IM; Work LM
Source: Self-asserted source
Chris McCabe via Europe PubMed Central
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An MRI-histological study of white matter in stroke-free SHRSP.

2013-05 | Journal article
DOI: 10.1038/jcbfm.2013.14
PMID: 23403376
PMC: PMC3652693
Contributors: Brittain JF; McCabe C; Khatun H; Kaushal N; Bridges LR; Holmes WM; Barrick TR; Graham D; Dominiczak AF; Mhairi Macrae I et al.
Source: Self-asserted source
Chris McCabe via Europe PubMed Central
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Positive impact of pre-stroke surgery on survival following transient focal ischemia in hypertensive rats.

2012-11 | Journal article
DOI: 10.1016/j.jneumeth.2012.09.001
PMID: 22975473
PMC: PMC3501564
Contributors: Ord EN; Shirley R; van Kralingen JC; Graves A; McClure JD; Wilkinson M; McCabe C; Macrae IM; Work LM
Source: Self-asserted source
Chris McCabe via Europe PubMed Central
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Penumbra detection using PWI/DWI mismatch MRI in a rat stroke model with and without comorbidity: comparison of methods.

2012-09 | Journal article
DOI: 10.1038/jcbfm.2012.69
PMID: 22669479
PMC: PMC3434632
Contributors: Reid E; Graham D; Lopez-Gonzalez MR; Holmes WM; Macrae IM; McCabe C
Source: Self-asserted source
Chris McCabe via Europe PubMed Central
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Noninvasive MRI measurement of CBF: evaluating an arterial spin labelling sequence with 99mTc-HMPAO CBF autoradiography in a rat stroke model.

2012-06 | Journal article
DOI: 10.1038/jcbfm.2012.19
PMID: 22472604
PMC: PMC3367221
Contributors: Baskerville TA; McCabe C; Weir CJ; Macrae IM; Holmes WM
Source: Self-asserted source
Chris McCabe via Europe PubMed Central
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Melarsoprol cyclodextrin inclusion complexes as promising oral candidates for the treatment of human African trypanosomiasis.

2011-09 | Journal article
DOI: 10.1371/journal.pntd.0001308
PMID: 21909447
PMC: PMC3167784
Contributors: Rodgers J; Jones A; Gibaud S; Bradley B; McCabe C; Barrett MP; Gettinby G; Kennedy PG
Source: Self-asserted source
Chris McCabe via Europe PubMed Central
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Influence of 100% and 40% oxygen on penumbral blood flow, oxygen level, and T2*-weighted MRI in a rat stroke model.

2011-08 | Journal article
DOI: 10.1038/jcbfm.2011.65
PMID: 21559031
PMC: PMC3170951
Contributors: Baskerville TA; Deuchar GA; McCabe C; Robertson CA; Holmes WM; Santosh C; Macrae IM
Source: Self-asserted source
Chris McCabe via Europe PubMed Central
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Stroke penumbra defined by an MRI-based oxygen challenge technique: 1. Validation using [14C]2-deoxyglucose autoradiography.

2011-08 | Journal article
DOI: 10.1038/jcbfm.2011.66
PMID: 21559032
PMC: PMC3154682
Contributors: Robertson CA; McCabe C; Gallagher L; Lopez-Gonzalez Mdel R; Holmes WM; Condon B; Muir KW; Santosh C; Macrae IM
Source: Self-asserted source
Chris McCabe via Europe PubMed Central
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Stroke penumbra defined by an MRI-based oxygen challenge technique: 2. Validation based on the consequences of reperfusion.

2011-08 | Journal article
DOI: 10.1038/jcbfm.2011.67
PMID: 21559030
PMC: PMC3160486
Contributors: Robertson CA; McCabe C; Gallagher L; Lopez-Gonzalez Mdel R; Holmes WM; Condon B; Muir KW; Santosh C; Macrae IM
Source: Self-asserted source
Chris McCabe via Europe PubMed Central
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Magnetic resonance imaging to assess blood-brain barrier damage in murine trypanosomiasis.

2011-02 | Journal article
DOI: 10.4269/ajtmh.2011.10-0487
PMID: 21292912
PMC: PMC3029195
Contributors: Rodgers J; McCabe C; Gettinby G; Bradley B; Condon B; Kennedy PG
Source: Self-asserted source
Chris McCabe via Europe PubMed Central
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T2*-weighted magnetic resonance imaging with hyperoxia in acute ischemic stroke.

2010-07 | Journal article
DOI: 10.1002/ana.22032
PMID: 20582987
Contributors: Dani KA; Santosh C; Brennan D; McCabe C; Holmes WM; Condon B; Hadley DM; Macrae IM; Shaw M; Muir KW
Source: Self-asserted source
Chris McCabe via Europe PubMed Central
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Response to Letter by Yao

2010-02-25 | Journal article
DOI: https://doi.org/10.1161/STROKEAHA.109.575704
Source: Self-asserted source
Chris McCabe
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Differences in the evolution of the ischemic penumbra in stroke-prone spontaneously hypertensive and Wistar-Kyoto rats.

2009-12 | Journal article
DOI: 10.1161/STROKEAHA.109.559021
PMID: 19797186
PMC: PMC3145096
Contributors: McCabe C; Gallagher L; Gsell W; Graham D; Dominiczak AF; Macrae IM
Source: Self-asserted source
Chris McCabe via Europe PubMed Central
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In ovo non-invasive quantification of the myocardial function and mass of chick embryos using magnetic resonance imaging.

2009-08 | Journal article
DOI: 10.1002/nbm.1386
PMID: 19322809
Contributors: Holmes WM; McCabe C; Mullin JM; Condon B; Bain MM
Source: Self-asserted source
Chris McCabe via Europe PubMed Central
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Potential use of oxygen as a metabolic biosensor in combination with T2*-weighted MRI to define the ischemic penumbra.

2008-10 | Journal article
DOI: 10.1038/jcbfm.2008.56
PMID: 18545262
PMC: PMC3119432
Contributors: Santosh C; Brennan D; McCabe C; Macrae IM; Holmes WM; Graham DI; Gallagher L; Condon B; Hadley DM; Muir KW et al.
Source: Self-asserted source
Chris McCabe via Europe PubMed Central
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Images in cardiovascular medicine. Noninvasive self-gated magnetic resonance cardiac imaging of developing chick embryos in ovo.

2008-05 | Journal article
DOI: 10.1161/CIRCULATIONAHA.107.747154
PMID: 18506012
Contributors: Holmes WM; McCabe C; Mullin JM; Condon B; Bain MM
Source: Self-asserted source
Chris McCabe via Europe PubMed Central
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GADD34 gene restores virulence in viral vector used in experimental stroke study.

2008-04 | Journal article
DOI: 10.1038/sj.jcbfm.9600565
PMID: 17928799
Contributors: McCabe C; White F; Brown SM; Macrae IM
Source: Self-asserted source
Chris McCabe via Europe PubMed Central
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Effects of magnesium treatment in a model of internal capsule lesion in spontaneously hypertensive rats.

2008-02 | Journal article
DOI: 10.1161/STROKEAHA.107.492934
PMID: 18174487
Contributors: Lecrux C; McCabe C; Weir CJ; Gallagher L; Mullin J; Touzani O; Muir KW; Lees KR; Macrae IM
Source: Self-asserted source
Chris McCabe via Europe PubMed Central
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Effects of magnesium treatment in a model of internal capsule lesion in spontaneously hypertensive rats

Journal of Cerebral Blood Flow and Metabolism
2007 | Journal article
EID:

2-s2.0-36348950842

Part of ISSN: 0271678X
Contributors: Lecrux, C.; McCabe, C.; Weir, C.J.; Gallagher, L.; Mullin, J.; Touzani, O.; Muir, K.W.; Lees, K.R.; Macrae, I.M.
Source: Self-asserted source
Chris McCabe via Scopus - Elsevier

Identification of the growth arrest and DNA damage protein GADD34 in the normal human heart and demonstration of alterations in expression following myocardial ischaemia.

2006-02 | Journal article
DOI: 10.1016/j.ijcard.2005.01.051
PMID: 16337513
Contributors: Morton E; Macrae IM; McCabe C; Brown SM; White F
Source: Self-asserted source
Chris McCabe via Europe PubMed Central
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Endothelin and the ischaemic heart.

2005-10 | Journal article
DOI: 10.2174/157016105774329417
PMID: 16248776
Contributors: Wainwright CL; McCabe C; Kane KA
Source: Self-asserted source
Chris McCabe via Europe PubMed Central
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Electrophysiological and haemodynamic effects of endothelin ETA and ETB receptors in normal and ischaemic working rabbit hearts.

2005-09 | Journal article
DOI: 10.1038/sj.bjp.0706304
PMID: 15980873
PMC: PMC1576251
Contributors: McCabe C; Hicks MN; Kane KA; Wainwright CL
Source: Self-asserted source
Chris McCabe via Europe PubMed Central
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