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ResearcherID: LTE-9357-2024
Loop profile: 477861
SciProfiles: 2593055

Countries

Czech Republic

Biography

Dr Sudhanshu Shekhar is a Scientist (Výzkumný pracovník) at the Laboratory of Gnotobiology, Institute of Microbiology of the Czech Academy of Sciences, Czech Republic. He received his MSc in Integrated Immunology and PhD in Infection and Immunity from the University of Oxford in England and the University of Manitoba in Canada, respectively. He then worked as a Postdoctoral and Senior Scientist at the University of Oslo, Norway, exploring host-microbiota interplay in animal models and humans. Of note, he is a registered veterinarian, who holds a DVM in Veterinary Medicine. Overall, his research interest and passion revolve around understanding and capitalizing on host-microbiota interactions in order to develop novel vaccines and therapeutics.

Activities

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Employment (3)

Czech Academy of Sciences, Institute of Microbiology: Prague, CZ

2024 to present | Scientist
Employment
Source: Self-asserted source
Sudhanshu Shekhar

University of Oslo: Oslo, Oslo, NO

2019 to 2022 | Senior Researcher
Employment
Source: Self-asserted source
Sudhanshu Shekhar

University of Oslo: Oslo, Oslo, NO

2015 to 2018 | Postdoctoral Researcher
Employment
Source: Self-asserted source
Sudhanshu Shekhar

Education and qualifications (2)

University of Manitoba: Winnipeg, MB, CA

2010 to 2015 | PhD (Medical Microbiology and Infectious Diseases)
Education
Source: Self-asserted source
Sudhanshu Shekhar

University of Oxford: Oxford, Oxfordshire, GB

2006 to 2007 | MSc (Nuffield Department of Surgical Sciences )
Education
Source: Self-asserted source
Sudhanshu Shekhar

Works (32)

Nasal microbiota transplantation: a gateway to novel treatments

Trends in Microbiology
2025-03 | Journal article
DOI: 10.1016/j.tim.2024.12.010
Contributors: Sudhanshu Shekhar; Martin Schwarzer; Achal Dhariwal; Fernanda Cristina Petersen
Source: check_circle
Crossref

Enhancement of Macrophage Immunity against Chlamydial Infection by Natural Killer T Cells

Cells
2024 | Journal article
DOI: 10.3390/CELLS13020133
WOSUID: WOS:001151958800001
Contributors: Peng, Ying; Qiao, Sai; Wang, Hong; Shekhar, Sudhanshu; Wang, Shuhe; Yang, Jie; Fan, Yijun; Yang, Xi
Source: check_circle
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HAMLET, a human milk protein-lipid complex, modulates amoxicillin induced changes in an <i>ex vivo</i> biofilm model of the oral microbiome

Frontiers in Microbiology
2024 | Journal article
DOI: 10.3389/FMICB.2024.1406190
WOSUID: WOS:001271726300001
Contributors: Brar, Navdeep Kaur; Dhariwal, Achal; Shekhar, Sudhanshu; Junges, Roger; Hakansson, Anders P.; Petersen, Fernanda Cristina
Source: check_circle
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Treatment of Mouse Infants with Amoxicillin, but Not the Human Milk-Derived Antimicrobial HAMLET, Impairs Lung Th17 Responses

Antibiotics
2023 | Journal article
DOI: 10.3390/ANTIBIOTICS12020423
WOSUID: WOS:000938832200001
Contributors: Shekhar, Sudhanshu; Brar, Navdeep Kaur; Hakansson, Anders P.; Petersen, Fernanda Cristina
Source: check_circle
Web of Science Researcher Profile Sync
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Suppressive effect of therapeutic antibiotic regimen on antipneumococcal Th1/Th17 responses in neonatal mice

Pediatric Research
2023-03 | Journal article
DOI: 10.1038/s41390-022-02115-7
Part of ISSN: 0031-3998
Part of ISSN: 1530-0447
Contributors: Sudhanshu Shekhar; Navdeep K. Brar; Fernanda C. Petersen
Source: Self-asserted source
Sudhanshu Shekhar
grade
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Effects of different amoxicillin treatment durations on microbiome diversity and composition in the gut

PLOS ONE
2022-10-27 | Journal article
DOI: 10.1371/journal.pone.0275737
Part of ISSN: 1932-6203
Contributors: Katrine Lekang; Sudhanshu Shekhar; Dag Berild; Fernanda Cristina Petersen; Hanne Cecilie Winther-Larsen
Source: Self-asserted source
Sudhanshu Shekhar
grade
Preferred source (of 2)‎

Vaccination With the Commensal Streptococcus mitis Expressing Pneumococcal Serotype 5 Capsule Elicits IgG/IgA and Th17 Responses Against Streptococcus pneumoniae

Frontiers in Immunology
2021-04-19 | Journal article
DOI: 10.3389/fimmu.2021.676488
Part of ISSN: 1664-3224
Contributors: Sudhanshu Shekhar; Heidi A. Åmdal; Fernanda Cristina Petersen
Source: Self-asserted source
Sudhanshu Shekhar
grade
Preferred source (of 2)‎

Semaphorin 3E Protects against Chlamydial Infection by Modulating Dendritic Cell Functions

The Journal of Immunology
2021-03-15 | Journal article | Author
DOI: 10.4049/jimmunol.2001013
Part of ISSN: 0022-1767
Part of ISSN: 1550-6606
Contributors: RONY THOMAS; Shuhe Wang; Sudhanshu Shekhar; Ying Peng; Sai Qiao; Chunyan Zhang; Lianyu Shan; Hesam Movassagh; Abdelilah Gounni; Jie Yang et al.
Source: Self-asserted source
Sudhanshu Shekhar
grade
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The Dark Side of Antibiotics: Adverse Effects on the Infant Immune Defense Against Infection

Frontiers in Pediatrics
2020-10-15 | Journal article
DOI: 10.3389/fped.2020.544460
Part of ISSN: 2296-2360
Contributors: Sudhanshu Shekhar; Fernanda Cristina Petersen
Source: Self-asserted source
Sudhanshu Shekhar
grade
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NK cells modulate T cell responses via interaction with dendritic cells in Chlamydophila pneumoniae infection

Cellular Immunology
2020-07 | Journal article
DOI: 10.1016/j.cellimm.2020.104132
Part of ISSN: 0008-8749
Contributors: Lei Zhao; Hong Wang; Rony Thomas; Xiaoling Gao; Hong Bai; Sudhanshu Shekhar; Shuhe Wang; Jie Yang; Weiming Zhao; Xi Yang
Source: Self-asserted source
Sudhanshu Shekhar
grade
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Pulmonary CD103+ dendritic cells: key regulators of immunity against infection

Cellular & Molecular Immunology
2020-06 | Journal article
DOI: 10.1038/s41423-020-0397-8
Part of ISSN: 1672-7681
Part of ISSN: 2042-0226
Contributors: Sudhanshu Shekhar; Xi Yang
Source: Self-asserted source
Sudhanshu Shekhar
grade
Preferred source (of 2)‎

Intranasal Immunization with the Commensal <i>Streptococcus mitis</i> Confers Protective Immunity against Pneumococcal Lung Infection

Applied and Environmental Microbiology
2019 | Journal article
DOI: 10.1128/AEM.02235-18
WOSUID: WOS:000460468400002
Contributors: Shekhar, Sudhanshu; Khan, Rabia; Schenck, Karl; Petersen, Fernanda Cristina
Source: check_circle
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Mouse IgG2a Antibodies Specific for the Commensal <i>Streptococcus mitis</i> Show Stronger Cross-Reactivity with <i>Streptococcus pneumoniae</i> than IgG1 Antibodies

Journal of Immunology Research
2019 | Journal article
DOI: 10.1155/2019/7906724
WOSUID: WOS:000487761100001
Contributors: Shekhar, Sudhanshu; Khan, Rabia; Khan, Ata Ul Razzaq; Petersen, Fernanda Cristina
Source: check_circle
Web of Science Researcher Profile Sync
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Editorial: Understanding and Exploiting Host-Commensal Interactions to Combat Pathogens

Frontiers in Immunology
2019-11-12 | Journal article
DOI: 10.3389/fimmu.2019.02645
Part of ISSN: 1664-3224
Contributors: Sudhanshu Shekhar; Fernanda Cristina Petersen; Xi Yang
Source: Self-asserted source
Sudhanshu Shekhar
grade
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Commensal Bacteria: An Emerging Player in Defense Against Respiratory Pathogens

Frontiers in Immunology
2019-05-31 | Journal article
DOI: 10.3389/fimmu.2019.01203
Part of ISSN: 1664-3224
Contributors: Rabia Khan; Fernanda Cristina Petersen; Sudhanshu Shekhar
Source: Self-asserted source
Sudhanshu Shekhar
grade
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CD103+ lung dendritic cells (LDCs) induce stronger Th1/Th17 immunity to a bacterial lung infection than CD11bhi LDCs

Cellular &amp; Molecular Immunology
2018-04 | Journal article
DOI: 10.1038/cmi.2016.68
Part of ISSN: 1672-7681
Part of ISSN: 2042-0226
Contributors: Sudhanshu Shekhar; Ying Peng; Shuhe Wang; Xi Yang
Source: Self-asserted source
Sudhanshu Shekhar
grade
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Antibodies Reactive to Commensal Streptococcus mitis Show Cross-Reactivity With Virulent Streptococcus pneumoniae Serotypes

Frontiers in Immunology
2018-04-16 | Journal article
DOI: 10.3389/fimmu.2018.00747
Part of ISSN: 1664-3224
Contributors: Sudhanshu Shekhar; Rabia Khan; Daniela M. Ferreira; Elena Mitsi; Esther German; Gro Herredsvela Rørvik; Dag Berild; Karl Schenck; Keehwan Kwon; Fernanda Petersen
Source: Self-asserted source
Sudhanshu Shekhar
grade
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Exploring Host–Commensal Interactions in the Respiratory Tract

Frontiers in Immunology
2018-01-17 | Journal article
DOI: 10.3389/fimmu.2017.01971
Part of ISSN: 1664-3224
Contributors: Sudhanshu Shekhar; Karl Schenck; Fernanda Cristina Petersen
Source: Self-asserted source
Sudhanshu Shekhar
grade
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Cytokines in Autoimmune Disease

Mediators of Inflammation
2017 | Journal article
DOI: 10.1155/2017/5089815
Part of ISSN: 0962-9351
Part of ISSN: 1466-1861
Contributors: Qingdong Guan; Xiaoling Gao; junhui wang; Yu Sun; Sudhanshu Shekhar
Source: Self-asserted source
Sudhanshu Shekhar
grade
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A Quorum-Sensing System That Regulates Streptococcus pneumoniae Biofilm Formation and Surface Polysaccharide Production

mSphere
2017-10-25 | Journal article
DOI: 10.1128/msphere.00324-17
Part of ISSN: 2379-5042
Contributors: Roger Junges; Gabriela Salvadori; Sudhanshu Shekhar; Heidi A. Åmdal; Jimstan N. Periselneris; Tsute Chen; Jeremy S. Brown; Fernanda C. Petersen
Source: Self-asserted source
Sudhanshu Shekhar
grade
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Invariant Natural Killer T Cells Promote T Cell Immunity by Modulating the Function of Lung Dendritic Cells during Chlamydia pneumoniae Infection

Journal of Innate Immunity
2015 | Journal article
DOI: 10.1159/000368779
Part of ISSN: 1662-811X
Part of ISSN: 1662-8128
Contributors: Sudhanshu Shekhar; Antony George Joyee; Xiaoling Gao; Ying Peng; Shuhe Wang; Jie Yang; Xi Yang
Source: Self-asserted source
Sudhanshu Shekhar
grade
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Natural killer cells in host defense against veterinary pathogens

Veterinary Immunology and Immunopathology
2015-11 | Journal article
DOI: 10.1016/j.vetimm.2015.10.001
Part of ISSN: 0165-2427
Contributors: Sudhanshu Shekhar; Xi Yang
Source: Self-asserted source
Sudhanshu Shekhar
grade
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NK cells modulate the lung dendritic cell‐mediated Th1/Th17 immunity during intracellular bacterial infection

European Journal of Immunology
2015-10 | Journal article
DOI: 10.1002/eji.201445390
Part of ISSN: 0014-2980
Part of ISSN: 1521-4141
Contributors: Sudhanshu Shekhar; Ying Peng; Xiaoling Gao; Antony G Joyee; Shuhe Wang; Hong Bai; Lei Zhao; Jie Yang; Xi Yang
Source: Self-asserted source
Sudhanshu Shekhar
grade
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Dynamics of NKT-Cell Responses to Chlamydial Infection

Frontiers in Immunology
2015-05-15 | Journal article
DOI: 10.3389/fimmu.2015.00233
Part of ISSN: 1664-3224
Contributors: Sudhanshu Shekhar; Antony George Joyee; Xi Yang
Source: Self-asserted source
Sudhanshu Shekhar
grade
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Human Immunodeficiency Virus Type 1 Employs the Cellular Dynein Light Chain 1 Protein for Reverse Transcription through Interaction with Its Integrase Protein

Journal of Virology
2015-04 | Journal article
DOI: 10.1128/jvi.03347-14
Part of ISSN: 0022-538X
Part of ISSN: 1098-5514
Contributors: Kallesh Danappa Jayappa; Zhujun Ao; Xiaoxia Wang; Andrew J. Mouland; Sudhanshu Shekhar; Xi Yang; Xiaojian Yao
Source: Self-asserted source
Sudhanshu Shekhar
grade
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Chlamydial Lung Infection Induces Transient IL-9 Production Which Is Redundant for Host Defense against Primary Infection

PLOS ONE
2015-02-03 | Journal article
DOI: 10.1371/journal.pone.0115195
Part of ISSN: 1932-6203
Contributors: Ying Peng; Xiaoling Gao; Jie Yang; Sudhanshu Shekhar; Shuhe Wang; Yijun Fan; Xi Yang
Source: Self-asserted source
Sudhanshu Shekhar

Invariant Natural Killer T Cells: Boon or Bane in Immunity to Intracellular Bacterial Infections?

Journal of Innate Immunity
2014 | Journal article
DOI: 10.1159/000361048
Part of ISSN: 1662-811X
Part of ISSN: 1662-8128
Contributors: Sudhanshu Shekhar; Antony George Joyee; Xi Yang
Source: Self-asserted source
Sudhanshu Shekhar
grade
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Interleukin-22 Promotes T Helper 1 (Th1)/Th17 Immunity in Chlamydial Lung Infection

Molecular Medicine
2014-01 | Journal article
DOI: 10.2119/molmed.2013.00115
Part of ISSN: 1076-1551
Part of ISSN: 1528-3658
Contributors: Ying Peng; Xiaoling Gao; Jie Yang; Sudhanshu Shekhar; Shuhe Wang; Yijun Fan; Weiming Zhao; Xi Yang
Source: Self-asserted source
Sudhanshu Shekhar
grade
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The darker side of follicular helper T cells: from autoimmunity to immunodeficiency

Cellular & Molecular Immunology
2012-09 | Journal article
DOI: 10.1038/cmi.2012.26
Part of ISSN: 1672-7681
Part of ISSN: 2042-0226
Contributors: Sudhanshu Shekhar; Xi Yang
Source: Self-asserted source
Sudhanshu Shekhar
grade
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Identification and phenotypic characterization of γδ T cells in rat lymph

Research in Veterinary Science
2012-08 | Journal article
DOI: 10.1016/j.rvsc.2011.07.014
Part of ISSN: 0034-5288
Contributors: Sudhanshu Shekhar; Simon Milling; Chris Jenkins; Gordon MacPherson
Source: Self-asserted source
Sudhanshu Shekhar
grade
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The glycolipid exoantigen derived from Chlamydia muridarum activates invariant natural killer T cells

Cellular & Molecular Immunology
2012-07 | Journal article
DOI: 10.1038/cmi.2012.19
Part of ISSN: 1672-7681
Part of ISSN: 2042-0226
Contributors: Ying Peng; Lei Zhao; Sudhanshu Shekhar; Lu Liu; Hong Wang; Qiang Chen; Xiaoling Gao; Xi Yang; Weiming Zhao
Source: Self-asserted source
Sudhanshu Shekhar
grade
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Migration of γδ T cells in steady-state conditions

Veterinary Immunology and Immunopathology
2012-06 | Journal article
DOI: 10.1016/j.vetimm.2012.03.016
Part of ISSN: 0165-2427
Contributors: Sudhanshu Shekhar; Simon Milling; Xi Yang
Source: Self-asserted source
Sudhanshu Shekhar
grade
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