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Works (3)

Identification of highly selective SIK1/2 inhibitors that modulate innate immune activation and suppress intestinal inflammation

Proceedings of the National Academy of Sciences
2024-01-02 | Journal article
DOI: 10.1073/pnas.2307086120
Contributors: Holger Babbe; Thomas B. Sundberg; Mark Tichenor; Mark Seierstad; Genesis Bacani; James Berstler; Wenying Chai; Leon Chang; De Michael Chung; Kevin Coe et al.
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Discovery of JNJ-64264681: A Potent and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase

Journal of Medicinal Chemistry
2022-11-10 | Journal article
DOI: 10.1021/acs.jmedchem.2c01026
Contributors: Mark S. Tichenor; John J. M. Wiener; Navin L. Rao; Genesis M. Bacani; Jianmei Wei; Charlotte Pooley Deckhut; J. Kent Barbay; Kevin D. Kreutter; Leon Chang; Kathleen W. Clancy et al.
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Discovery of a Potent and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase with Oral Anti-Inflammatory Activity

ACS Medicinal Chemistry Letters
2021-05-13 | Journal article
DOI: 10.1021/acsmedchemlett.1c00044
Contributors: Mark S. Tichenor; John J. M. Wiener; Navin L. Rao; Charlotte Pooley Deckhut; J. Kent Barbay; Kevin D. Kreutter; Genesis M. Bacani; Jianmei Wei; Leon Chang; Heather E. Murrey et al.
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Peer review (3 reviews for 2 publications/grants)

Review activity for ACS medicinal chemistry letters. (1)
Review activity for Journal of medicinal chemistry. (2)
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