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Employment (1)

University of Virginia: Charlottesville, VA, US

2018-07-01 to present | Associate Professor (Microbiology, Immunology, and Cancer Biology)
Employment
Source: Self-asserted source
Kwon-Sik Park

Education and qualifications (2)

University of Cincinnati College of Medicine: Cincinnati, OH, US

2000 to 2006 | Ph.D. (Molecular and Developmental Biology at Cincinnati Children's Hospital Medical Center)
Education
Source: Self-asserted source
Kwon-Sik Park

Chung-Ang University: Seoul, Seoul, KR

1991 to 1996 | B.S. (Life Sciences)
Education
Source: Self-asserted source
Kwon-Sik Park

Works (50 of 58)

Items per page:
Page 1 of 2

Genetically-engineered mouse models of small cell lung cancer: the next generation

Oncogene
2024-02-09 | Journal article
DOI: 10.1038/s41388-023-02929-7
Contributors: Matthew G. Oser; David MacPherson; Trudy G. Oliver; Julien Sage; Kwon-Sik Park
Source: check_circle
Crossref

Robo1 loss has pleiotropic effects on postnatal development and survival

2023-08-02 | Preprint
DOI: 10.1101/2023.08.01.551555
Contributors: Nicole A. Kirk; Ye Eun Hwang; Seul Gi Lee; Kee-Beom Kim; Kwon-Sik Park
Source: check_circle
Crossref

CRACD suppresses neuroendocrinal plasticity of lung adenocarcinoma

2023-04-21 | Preprint
DOI: 10.1101/2023.04.19.537576
Contributors: Bongjun Kim; Shengzhe Zhang; Yuanjian Huang; Kyung-Pil Ko; Gengyi Zou; Jie Zhang; Sohee Jun; Kee-Beom Kim; Youn-Sang Jung; Kwon-Sik Park et al.
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Crossref

Data from FGFR1 Is Critical for RBL2 Loss–Driven Tumor Development and Requires PLCG1 Activation for Continued Growth of Small Cell Lung Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.c.6512283
Contributors: Kee-Beom Kim; Youngchul Kim; Christopher J. Rivard; Dong-Wook Kim; Kwon-Sik Park
Source: check_circle
Crossref

Data from FGFR1 Is Critical for RBL2 Loss–Driven Tumor Development and Requires PLCG1 Activation for Continued Growth of Small Cell Lung Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.c.6512283.v1
Contributors: Kee-Beom Kim; Youngchul Kim; Christopher J. Rivard; Dong-Wook Kim; Kwon-Sik Park
Source: check_circle
Crossref

Data from Fragmentation of Small-Cell Lung Cancer Regulatory States in Heterotypic Microenvironments

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.c.6513091
Contributors: Dylan L. Schaff; Shambhavi Singh; Kee-Beom Kim; Matthew D. Sutcliffe; Kwon-Sik Park; Kevin A. Janes
Source: check_circle
Crossref

Data from Fragmentation of Small-Cell Lung Cancer Regulatory States in Heterotypic Microenvironments

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.c.6513091.v1
Contributors: Dylan L. Schaff; Shambhavi Singh; Kee-Beom Kim; Matthew D. Sutcliffe; Kwon-Sik Park; Kevin A. Janes
Source: check_circle
Crossref

Supplementary Data 1 from FGFR1 Is Critical for RBL2 Loss–Driven Tumor Development and Requires PLCG1 Activation for Continued Growth of Small Cell Lung Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22426293
Contributors: Kee-Beom Kim; Youngchul Kim; Christopher J. Rivard; Dong-Wook Kim; Kwon-Sik Park
Source: check_circle
Crossref

Supplementary Data 1 from FGFR1 Is Critical for RBL2 Loss–Driven Tumor Development and Requires PLCG1 Activation for Continued Growth of Small Cell Lung Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22426293.v1
Contributors: Kee-Beom Kim; Youngchul Kim; Christopher J. Rivard; Dong-Wook Kim; Kwon-Sik Park
Source: check_circle
Crossref

Supplementary Data 2 from FGFR1 Is Critical for RBL2 Loss–Driven Tumor Development and Requires PLCG1 Activation for Continued Growth of Small Cell Lung Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22426290
Contributors: Kee-Beom Kim; Youngchul Kim; Christopher J. Rivard; Dong-Wook Kim; Kwon-Sik Park
Source: check_circle
Crossref

Supplementary Data 2 from FGFR1 Is Critical for RBL2 Loss–Driven Tumor Development and Requires PLCG1 Activation for Continued Growth of Small Cell Lung Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22426290.v1
Contributors: Kee-Beom Kim; Youngchul Kim; Christopher J. Rivard; Dong-Wook Kim; Kwon-Sik Park
Source: check_circle
Crossref

Supplementary Data 3 from FGFR1 Is Critical for RBL2 Loss–Driven Tumor Development and Requires PLCG1 Activation for Continued Growth of Small Cell Lung Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22426287
Contributors: Kee-Beom Kim; Youngchul Kim; Christopher J. Rivard; Dong-Wook Kim; Kwon-Sik Park
Source: check_circle
Crossref

Supplementary Data 3 from FGFR1 Is Critical for RBL2 Loss–Driven Tumor Development and Requires PLCG1 Activation for Continued Growth of Small Cell Lung Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22426287.v1
Contributors: Kee-Beom Kim; Youngchul Kim; Christopher J. Rivard; Dong-Wook Kim; Kwon-Sik Park
Source: check_circle
Crossref

Supplementary Data from Fragmentation of Small-Cell Lung Cancer Regulatory States in Heterotypic Microenvironments

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22428661.v1
Contributors: Dylan L. Schaff; Shambhavi Singh; Kee-Beom Kim; Matthew D. Sutcliffe; Kwon-Sik Park; Kevin A. Janes
Source: check_circle
Crossref

Supplementary Data from Fragmentation of Small-Cell Lung Cancer Regulatory States in Heterotypic Microenvironments

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22428661
Contributors: Dylan L. Schaff; Shambhavi Singh; Kee-Beom Kim; Matthew D. Sutcliffe; Kwon-Sik Park; Kevin A. Janes
Source: check_circle
Crossref

Supplementary Fig 1 from FGFR1 Is Critical for RBL2 Loss–Driven Tumor Development and Requires PLCG1 Activation for Continued Growth of Small Cell Lung Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22426284
Contributors: Kee-Beom Kim; Youngchul Kim; Christopher J. Rivard; Dong-Wook Kim; Kwon-Sik Park
Source: check_circle
Crossref

Supplementary Fig 1 from FGFR1 Is Critical for RBL2 Loss–Driven Tumor Development and Requires PLCG1 Activation for Continued Growth of Small Cell Lung Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22426284.v1
Contributors: Kee-Beom Kim; Youngchul Kim; Christopher J. Rivard; Dong-Wook Kim; Kwon-Sik Park
Source: check_circle
Crossref

Supplementary Fig 2 from FGFR1 Is Critical for RBL2 Loss–Driven Tumor Development and Requires PLCG1 Activation for Continued Growth of Small Cell Lung Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22426281
Contributors: Kee-Beom Kim; Youngchul Kim; Christopher J. Rivard; Dong-Wook Kim; Kwon-Sik Park
Source: check_circle
Crossref

Supplementary Fig 2 from FGFR1 Is Critical for RBL2 Loss–Driven Tumor Development and Requires PLCG1 Activation for Continued Growth of Small Cell Lung Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22426281.v1
Contributors: Kee-Beom Kim; Youngchul Kim; Christopher J. Rivard; Dong-Wook Kim; Kwon-Sik Park
Source: check_circle
Crossref

Supplementary Fig 3 from FGFR1 Is Critical for RBL2 Loss–Driven Tumor Development and Requires PLCG1 Activation for Continued Growth of Small Cell Lung Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22426278
Contributors: Kee-Beom Kim; Youngchul Kim; Christopher J. Rivard; Dong-Wook Kim; Kwon-Sik Park
Source: check_circle
Crossref

Supplementary Fig 3 from FGFR1 Is Critical for RBL2 Loss–Driven Tumor Development and Requires PLCG1 Activation for Continued Growth of Small Cell Lung Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22426278.v1
Contributors: Kee-Beom Kim; Youngchul Kim; Christopher J. Rivard; Dong-Wook Kim; Kwon-Sik Park
Source: check_circle
Crossref

Supplementary Fig 4 from FGFR1 Is Critical for RBL2 Loss–Driven Tumor Development and Requires PLCG1 Activation for Continued Growth of Small Cell Lung Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22426275
Contributors: Kee-Beom Kim; Youngchul Kim; Christopher J. Rivard; Dong-Wook Kim; Kwon-Sik Park
Source: check_circle
Crossref

Supplementary Fig 4 from FGFR1 Is Critical for RBL2 Loss–Driven Tumor Development and Requires PLCG1 Activation for Continued Growth of Small Cell Lung Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22426275.v1
Contributors: Kee-Beom Kim; Youngchul Kim; Christopher J. Rivard; Dong-Wook Kim; Kwon-Sik Park
Source: check_circle
Crossref

Supplementary File S1 from Fragmentation of Small-Cell Lung Cancer Regulatory States in Heterotypic Microenvironments

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22428658.v1
Contributors: Dylan L. Schaff; Shambhavi Singh; Kee-Beom Kim; Matthew D. Sutcliffe; Kwon-Sik Park; Kevin A. Janes
Source: check_circle
Crossref

Supplementary File S1 from Fragmentation of Small-Cell Lung Cancer Regulatory States in Heterotypic Microenvironments

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22428658
Contributors: Dylan L. Schaff; Shambhavi Singh; Kee-Beom Kim; Matthew D. Sutcliffe; Kwon-Sik Park; Kevin A. Janes
Source: check_circle
Crossref

Supplementary File S2 from Fragmentation of Small-Cell Lung Cancer Regulatory States in Heterotypic Microenvironments

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22428655.v1
Contributors: Dylan L. Schaff; Shambhavi Singh; Kee-Beom Kim; Matthew D. Sutcliffe; Kwon-Sik Park; Kevin A. Janes
Source: check_circle
Crossref

Supplementary File S2 from Fragmentation of Small-Cell Lung Cancer Regulatory States in Heterotypic Microenvironments

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22428655
Contributors: Dylan L. Schaff; Shambhavi Singh; Kee-Beom Kim; Matthew D. Sutcliffe; Kwon-Sik Park; Kevin A. Janes
Source: check_circle
Crossref

Supplementary Methods from FGFR1 Is Critical for RBL2 Loss–Driven Tumor Development and Requires PLCG1 Activation for Continued Growth of Small Cell Lung Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22426272
Contributors: Kee-Beom Kim; Youngchul Kim; Christopher J. Rivard; Dong-Wook Kim; Kwon-Sik Park
Source: check_circle
Crossref

Supplementary Methods from FGFR1 Is Critical for RBL2 Loss–Driven Tumor Development and Requires PLCG1 Activation for Continued Growth of Small Cell Lung Cancer

2023-03-31 | Preprint
DOI: 10.1158/0008-5472.22426272.v1
Contributors: Kee-Beom Kim; Youngchul Kim; Christopher J. Rivard; Dong-Wook Kim; Kwon-Sik Park
Source: check_circle
Crossref

Effect of chromatin modifiers on the plasticity and immunogenicity of small-cell lung cancer

Experimental & Molecular Medicine
2022-12-12 | Journal article
DOI: 10.1038/s12276-022-00905-x
Contributors: Nicole A. Kirk; Kee-Beom Kim; Kwon-Sik Park
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Crossref

WNT5A–RHOA Signaling Is a Driver of Tumorigenesis and Represents a Therapeutically Actionable Vulnerability in Small Cell Lung Cancer

Cancer Research
2022-11-15 | Journal article | Author
DOI: 10.1158/0008-5472.can-22-1170
Part of ISSN: 0008-5472
Part of ISSN: 1538-7445
Contributors: Kee-Beom Kim; DONG-WOOK KIM; youngchul kim; Jun Tang; Nicole Kirk; Anna Gan; Bongjun Kim; Bingliang Fang; JAE-IL PARK; Yi Zheng et al.
Source: Self-asserted source
Kwon-Sik Park

Opa1 and Drp1 reciprocally regulate cristae morphology, ETC function, and NAD+ regeneration in KRas-mutant lung adenocarcinoma

2022-06-01 | Preprint
DOI: 10.1101/2022.06.01.494337
Contributors: Dane T. Sessions; Kee-Beom Kim; Jennifer A. Kashatus; Nikolas Churchill; Kwon-Sik Park; Marty W. Mayo; Hiromi Sesaki; David F. Kashatus
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Crossref

KIX domain determines a selective tumor-promoting role for EP300 and its vulnerability in small cell lung cancer

Science Advances
2022-02-18 | Journal article | Author
DOI: 10.1126/sciadv.abl4618
Part of ISSN: 2375-2548
Contributors: Kee-Beom Kim; Ashish; Dong-Wook Kim; Yongming Xue; Yuanjian Huang; Pei-Chi Hou; Yunpeng Zhou; Leilani J. Miranda; JAE-IL PARK; Xiaobing Shi et al.
Source: Self-asserted source
Kwon-Sik Park

Fragmentation of Small-Cell Lung Cancer Regulatory States in Heterotypic Microenvironments

Cancer Research
2021-04-01 | Journal article
DOI: 10.1158/0008-5472.CAN-20-1036
Contributors: Dylan L. Schaff; Shambhavi Singh; Kee-Beom Kim; Matthew D. Sutcliffe; Kwon-Sik Park; Kevin A. Janes
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Crossref

BCAT1 affects mitochondrial metabolism independently of leucine transamination in activated human macrophages

Journal of Cell Science
2020-11-15 | Journal article
DOI: 10.1242/jcs.247957
Contributors: Jeong-Hun Ko; Antoni Olona; Adonia E. Papathanassiu; Norzawani Buang; Kwon-Sik Park; Ana S. H. Costa; Claudio Mauro; Christian Frezza; Jacques Behmoaras
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Crossref

FGFR1 Is Critical for RBL2 Loss–Driven Tumor Development and Requires PLCG1 Activation for Continued Growth of Small Cell Lung Cancer

Cancer Research
2020-11-15 | Journal article
DOI: 10.1158/0008-5472.CAN-20-1453
Contributors: Kee-Beom Kim; Youngchul Kim; Christopher J. Rivard; Dong-Wook Kim; Kwon-Sik Park
Source: check_circle
Crossref

New Approaches to SCLC Therapy: From the Laboratory to the Clinic

Journal of Thoracic Oncology
2020-04 | Journal article
DOI: 10.1016/j.jtho.2020.01.016
Part of ISSN: 1556-0864
Contributors: Kwon-Sik Park; John T. Poirier; Julie George; Taofeek K. Owonikoko; Anton Berns; Elisabeth Brambilla; Lauren A. Byers; David Carbone; Huanhuan J. Chen; Camilla L. Christensen et al.
Source: Self-asserted source
Kwon-Sik Park

Fragmentation of Small-cell Lung Cancer Regulatory States in Heterotypic Microenvironments

2020-03-31 | Preprint
DOI: 10.1101/2020.03.30.017210
Contributors: Dylan L. Schaff; Shambhavi Singh; Kee-Beom Kim; Matthew D. Sutcliffe; Kwon-Sik Park; Kevin A. Janes
Source: check_circle
Crossref

A trans-eQTL network regulates osteoclast multinucleation and bone mass

2020-02-13 | Preprint
DOI: 10.1101/2020.02.13.947705
Contributors: Marie Pereira; Jeong-Hun Ko; John Logan; Hayley Protheroe; Kee-Beom Kim; Amelia Li Min Tan; Kwon-Sik Park; Maxime Rotival; Enrico Petretto; J. H. Duncan Bassett et al.
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Crossref

In situ 10-cell RNA sequencing in tissue and tumor biopsy samples

Scientific Reports
2019-12 | Journal article
DOI: 10.1038/s41598-019-41235-9
Part of ISSN: 2045-2322
Contributors: Kwon-Sik Park; Shambhavi Singh; Lixin Wang; Dylan L. Schaff; Matthew Sutcliffe; Alex F. Koeppel; Jungeun Kim; Onengut-Gumuscu; Kwon-Sik Park; Hui Zong et al.
Source: Self-asserted source
Kwon-Sik Park

Recent progress in mapping the emerging landscape of the small-cell lung cancer genome

Experimental & Molecular Medicine
2019-12 | Journal article
DOI: 10.1038/s12276-019-0349-5
Contributors: Kee-Beom Kim; Colin T. Dunn; Kwon-Sik Park
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Crossref

<i>Crebbp</i> Loss Drives Small Cell Lung Cancer and Increases Sensitivity to HDAC Inhibition

Cancer Discovery
2018-11-01 | Journal article | Author
DOI: 10.1158/2159-8290.cd-18-0385
Part of ISSN: 2159-8274
Part of ISSN: 2159-8290
Contributors: Deshui Jia; Arnaud Augert; Dong-Wook Kim; Emily Eastwood; Nan Wu; Ali H. Ibrahim; Kee-Beom Kim; Colin T. Dunn; Smitha P.S. Pillai; Adi F. Gazdar et al.
Source: Self-asserted source
Kwon-Sik Park

Intertumoral Heterogeneity in SCLC Is Influenced by the Cell Type of Origin

Cancer Discovery
2018-10-01 | Journal article
DOI: 10.1158/2159-8290.cd-17-0987
Part of ISSN: 2159-8274
Part of ISSN: 2159-8290
Contributors: Kwon-Sik Park; Dian Yang; Sarah K. Denny; Peyton G. Greenside; Andrea C. Chaikovsky; Jennifer J. Brady; Youcef Ouadah; Jeffrey M. Granja; Nadine S. Jahchan; Jing Shan Lim et al.
Source: Self-asserted source
Kwon-Sik Park

The role of canonical and non-canonical Hedgehog signaling in tumor progression in a mouse model of small cell lung cancer

Oncogene
2017-09 | Journal article
DOI: 10.1038/onc.2017.173
Part of ISSN: 0950-9232
Part of ISSN: 1476-5594
Contributors: Kwon-Sik Park; A Szczepny; S Rogers; W S N Jayasekara; K Park; R A McCloy; C R Cochrane; V Ganju; W A Cooper; J Sage et al.
Source: Self-asserted source
Kwon-Sik Park

Nfib Promotes Metastasis through a Widespread Increase in Chromatin Accessibility

Cell
2016-07 | Journal article
DOI: 10.1016/j.cell.2016.05.052
Part of ISSN: 0092-8674
Contributors: Kwon-Sik Park; Sarah K. Denny; Dian Yang; Chen-Hua Chuang; Jennifer J. Brady; Jing Shan Lim; Barbara M. Grüner; Shin-Heng Chiou; Alicia N. Schep; Jessika Baral et al.
Source: Self-asserted source
Kwon-Sik Park

Genetic requirement for <i>Mycl</i> and efficacy of RNA Pol I inhibition in mouse models of small cell lung cancer

Genes &amp; Development
2016-06-01 | Journal article
DOI: 10.1101/gad.279307.116
Part of ISSN: 0890-9369
Part of ISSN: 1549-5477
Contributors: Kwon-Sik Park; Dong-Wook Kim; Nan Wu; Young-Chul Kim; Pei Feng Cheng; Ryan Basom; Dongkyoon Kim; Colin T. Dunn; Anastasia Y. Lee; Keebeom Kim et al.
Source: Self-asserted source
Kwon-Sik Park

Comprehensive genomic profiles of small cell lung cancer

Nature
2015-08-06 | Journal article
DOI: 10.1038/nature14664
Part of ISSN: 0028-0836
Part of ISSN: 1476-4687
Contributors: Kwon-Sik Park; Julie George; Jing Shan Lim; Se Jin Jang; Yupeng Cun; Luka Ozretić; Gu Kong; Frauke Leenders; Xin Lu; Lynnette Fernández-Cuesta et al.
Source: Self-asserted source
Kwon-Sik Park

A Drug Repositioning Approach Identifies Tricyclic Antidepressants as Inhibitors of Small Cell Lung Cancer and Other Neuroendocrine Tumors

Cancer Discovery
2013-12-01 | Journal article
DOI: 10.1158/2159-8290.cd-13-0183
Part of ISSN: 2159-8274
Part of ISSN: 2159-8290
Contributors: Kwon-Sik Park; Nadine S. Jahchan; Joel T. Dudley; Pawel K. Mazur; Natasha Flores; Dian Yang; Alec Palmerton; Anne-Flore Zmoos; Dedeepya Vaka; Kim Q.T. Tran et al.
Source: Self-asserted source
Kwon-Sik Park

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

Nature Genetics
2012-10 | Journal article
DOI: 10.1038/ng.2396
Part of ISSN: 1061-4036
Part of ISSN: 1546-1718
Contributors: Kwon-Sik Park; Martin Peifer; Lynnette Fernández-Cuesta; Martin L Sos; Julie George; Danila Seidel; Lawryn H Kasper; Dennis Plenker; Frauke Leenders; Ruping Sun et al.
Source: Self-asserted source
Kwon-Sik Park

A crucial requirement for Hedgehog signaling in small cell lung cancer

Nature Medicine
2011-11 | Journal article
DOI: 10.1038/nm.2473
Part of ISSN: 1078-8956
Part of ISSN: 1546-170X
Contributors: Kwon-Sik Park; Kwon-Sik Park; Luciano G Martelotto; Martin Peifer; Martin L Sos; Anthony N Karnezis; Moe R Mahjoub; Katie Bernard; Jamie F Conklin; Anette Szczepny et al.
Source: Self-asserted source
Kwon-Sik Park
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Peer review (2 reviews for 1 publication/grant)

Review activity for Nature cell biology (2)
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