Personal information

Verified email addresses

Chemistry, Chemical Biology, Enzymology, Radical SAM Enzyme
Japan

Activities

Employment (3)

Institute of Science Tokyo: Tokyo, JP

2024-10-01 to present | Assistant Professor (Department of Chemistry)
Employment
Source: Self-asserted source
Shusuke Sato

The University of Texas at Austin: Austin, TX, US

2021-10-01 to 2024-09-30 | Postdoc (Division of Chemical Biology and Medicinal Chemistry)
Employment
Source: Self-asserted source
Shusuke Sato

Tokyo Institute of Technology: Tokyo, Tôkyô, JP

2021-04-01 to 2021-09-30 | Postdoc (Department of Chemistry)
Employment
Source: Self-asserted source
Shusuke Sato

Education and qualifications (3)

Tokyo Institute of Technology: Tokyo, Tôkyô, JP

2018-04-01 to 2021-03-31 | Doctor (Department of Chemistry)
Education
Source: Self-asserted source
Shusuke Sato

Tokyo Institute of Technology: Tokyo, Tôkyô, JP

2016-04-01 to 2018-03-31 | Master (Department of Chemistry)
Education
Source: Self-asserted source
Shusuke Sato

Tokyo Institute of Technology: Tokyo, Tôkyô, JP

2011-04-01 to 2015-03-31 | Bachelor (School of Science)
Education
Source: Self-asserted source
Shusuke Sato

Funding (1)

炭素-炭素結合形成に関わるラジカルS-アデノシル-L-メチオニン酵素の機能解析

2019-04 to 2021-03 | Grant
JSPS (Tokyo, JP)
GRANT_NUMBER: 19J11692
Source: Self-asserted source
Shusuke Sato

Works (13)

Complete In Vitro Reconstitution of the Apramycin Biosynthetic Pathway Demonstrates the Unusual Incorporation of a β-d-Sugar Nucleotide in the Final Glycosylation Step

Journal of the American Chemical Society
2024-04-10 | Journal article
Contributors: Shusuke Sato; Po-Hsun Fan; Yu-Cheng Yeh; Hung-wen Liu
Source: check_circle
Crossref

Biosynthetic Origin of the Octose Core and Its Mechanism of Assembly during Apramycin Biosynthesis

Journal of the American Chemical Society
2023-10-04 | Journal article
Contributors: Po-Hsun Fan; Shusuke Sato; Yu-Cheng Yeh; Hung-wen Liu
Source: check_circle
Crossref

Mechanism of S-Adenosyl-l-methionine C-Methylation by Cobalamin-dependent Radical S-Adenosyl-l-methionine Methylase in 1-Amino-2-methylcyclopropanecarboxylic Acid Biosynthesis

Organic Letters
2022-12-16 | Journal article
Contributors: Fumitaka Kudo; Atsushi Minato; Shusuke Sato; Nayuta Nagano; Chitose Maruyama; Yoshimitsu Hamano; Junko Hashimoto; Ikuko Kozone; Kazuo Shin-ya; Tadashi Eguchi
Source: check_circle
Crossref

Identification of the Early Steps in Herbicidin Biosynthesis Reveals an Atypical Mechanism of C-Glycosylation

Journal of the American Chemical Society
2022-08-31 | Journal article
Contributors: Zhang Chen; Shusuke Sato; Yujie Geng; Jiawei Zhang; Hung-wen Liu
Source: check_circle
Crossref

Characterization of the cobalamin-dependent radical S-adenosyl-l-methionine enzyme C-methyltransferase Fom3 in fosfomycin biosynthesis

Methods in Enzymology
2022-01-01 | Book chapter
Part of ISBN: 9780323955577
Part of ISSN: 0076-6879
Contributors: Shusuke Sato; Fumitaka Kudo; Tadashi Eguchi
Source: Self-asserted source
Shusuke Sato

Biochemical and Mutational Analysis of Radical S-Adenosyl-L-Methionine Adenosylhopane Synthase HpnH from Zymomonas mobilis Reveals that the Conserved Residue Cysteine-106 Reduces a Radical Intermediate and Determines the Stereochemistry

Biochemistry
2021-09-10 | Journal article
Part of ISSN: 0006-2960
Part of ISSN: 1520-4995
Source: Self-asserted source
Shusuke Sato

C-Methylation of S-adenosyl-L-Methionine Occurs Prior to Cyclopropanation in the Biosynthesis of 1-Amino-2-Methylcyclopropanecarboxylic Acid (Norcoronamic Acid) in a Bacterium

Biomolecules
2020-05-16 | Journal article
Contributors: Chitose Maruyama; Yukiko Chinone; Shusuke Sato; Fumitaka Kudo; Kosuke Ohsawa; Junya Kubota; Junko Hashimoto; Ikuko Kozone; Takayuki Doi; Kazuo Shin-ya et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Characterization of Radical SAM Adenosylhopane Synthase, HpnH, which Catalyzes the 5′‐Deoxyadenosyl Radical Addition to Diploptene in the Biosynthesis of C35 Bacteriohopanepolyols

Angewandte Chemie International Edition
2020-01-02 | Journal article
Part of ISSN: 1433-7851
Part of ISSN: 1521-3773
Source: Self-asserted source
Shusuke Sato

Functional Characterization of 3‐Aminobenzoic Acid Adenylation Enzyme PctU and UDP‐N‐Acetyl‐D‐Glucosamine: 3‐Aminobenzoyl‐ACP Glycosyltransferase PctL in Pactamycin Biosynthesis

ChemBioChem
2019-09-30 | Journal article
Part of ISSN: 1439-4227
Part of ISSN: 1439-7633
Source: Self-asserted source
Shusuke Sato

C-Methylation Catalyzed by Fom3, a Cobalamin-Dependent Radical S-adenosyl-l-methionine Enzyme in Fosfomycin Biosynthesis, Proceeds with Inversion of Configuration

Biochemistry
2018-08-21 | Journal article
Part of ISSN: 0006-2960
Part of ISSN: 1520-4995
Source: Self-asserted source
Shusuke Sato

Biochemical and Structural Analysis of FomD That Catalyzes the Hydrolysis of Cytidylyl (S)-2-Hydroxypropylphosphonate in Fosfomycin Biosynthesis

Biochemistry
2018-08-14 | Journal article
Part of ISSN: 0006-2960
Part of ISSN: 1520-4995
Source: Self-asserted source
Shusuke Sato

Fosfomycin Biosynthesis via Transient Cytidylylation of 2-Hydroxyethylphosphonate by the Bifunctional Fom1 Enzyme

ACS Chemical Biology
2017-08-18 | Journal article
Part of ISSN: 1554-8929
Part of ISSN: 1554-8937
Source: Self-asserted source
Shusuke Sato

Methylcobalamin-Dependent Radical SAM C-Methyltransferase Fom3 Recognizes Cytidylyl-2-hydroxyethylphosphonate and Catalyzes the Nonstereoselective C-Methylation in Fosfomycin Biosynthesis

Biochemistry
2017-07-18 | Journal article
Part of ISSN: 0006-2960
Part of ISSN: 1520-4995
Source: Self-asserted source
Shusuke Sato