Personal information

Synthetic Biology, Gene Synthesis, Systems Biology, Translation, Transcription, Genome Engineering, Genome Sequencing, Immunology, T cells, Multiplexed screens, Chimeric Antigen Receptors, Protein Engineering
United States

Activities

Employment (1)

University of California, San Francisco: San Francisco, CA, US

Postdoctoral Fellow (Microbiology and Immunology)
Employment
Source: Self-asserted source
Daniel B. Goodman

Education and qualifications (1)

Massachusetts Institute of Technology: Boston, MA, US

2016-06-01 | Doctor of Philosophy, Bioinformatics and Integrative Genomics (Institute of Medical Engineering and Science)
Qualification
Source: Self-asserted source
Daniel B. Goodman

Works (34)

SEED-Selection enables high-efficiency enrichment of primary T cells edited at multiple loci

Nature Biotechnology
2025-02-05 | Journal article
Contributors: Christopher R. Chang; Vivasvan S. Vykunta; Jae Hyun J. Lee; Ke Li; Clara Kochendoerfer; Joseph J. Muldoon; Charlotte H. Wang; Thomas Mazumder; Yang Sun; Daniel B. Goodman et al.
Source: check_circle
Crossref

Naturally occurring T cell mutations enhance engineered T cell therapies

Nature
2024-02-15 | Journal article
Contributors: Julie Garcia; Jay Daniels; Yujin Lee; Iowis Zhu; Kathleen Cheng; Qing Liu; Daniel Goodman; Cassandra Burnett; Calvin Law; Chloë Thienpont et al.
Source: check_circle
Crossref

Ultra-high efficiency T cell reprogramming at multiple loci with SEED-Selection

2024-02-07 | Preprint
Contributors: Christopher R. Chang; Vivasvan S. Vykunta; Daniel B. Goodman; Joseph J. Muldoon; William A. Nyberg; Chang Liu; Vincent Allain; Allison Rothrock; Charlotte H. Wang; Alexander Marson et al.
Source: check_circle
Crossref

Pooled screening of CAR T cells identifies diverse immune signaling domains for next-generation immunotherapies

Science Translational Medicine
2022-11-09 | Journal article
Contributors: Daniel B. Goodman; Camillia S. Azimi; Kendall Kearns; Alexis Talbot; Kiavash Garakani; Julie Garcia; Nisarg Patel; Byungjin Hwang; David Lee; Emily Park et al.
Source: check_circle
Crossref

Pooled screening of CAR T cells identifies non-native signaling domains for next-generation immunotherapies

2021-07-12 | Other
Contributors: Daniel B. Goodman; Camillia S. Azimi; Kendall Kearns; Kiavash Garakani; Julie Garcia; Nisarg Patel; Byungjin Hwang; David Lee; Emily Park; Chun Jimmie Ye et al.
Source: check_circle
Crossref

High-throughput functional variant screens via in vivo production of single-stranded DNA

Proceedings of the National Academy of Sciences
2021-05-04 | Journal article
Contributors: Max G. Schubert; Daniel B. Goodman; Timothy M. Wannier; Divjot Kaur; Fahim Farzadfard; Timothy K. Lu; Seth L. Shipman; George M. Church
Source: check_circle
Crossref

High throughput functional variant screens via in-vivo production of single-stranded DNA

bioRxiv
2020 | Journal article
Source: Self-asserted source
Daniel B. Goodman

Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency

Nature biotechnology
2020 | Journal article
Source: Self-asserted source
Daniel B. Goodman

Pooled knockin targeting for genome engineering of cellular immunotherapies

Cell
2020 | Journal article
Source: Self-asserted source
Daniel B. Goodman

Methods for Rule-based Genome Design

2020-02 | Other
Source: Self-asserted source
Daniel B. Goodman

A Multiplexed Assay for Exon Recognition Reveals That an Unappreciated Fraction of Rare Genetic Variants Cause Large-Effect Disruptions to Splicing

Molecular Cell
2018 | Journal article
Source: Self-asserted source
Daniel B. Goodman

Enabling multiplexed testing of pooled donor cells through whole-genome sequencing

Genome medicine
2018 | Journal article
Source: Self-asserted source
Daniel B. Goodman

Large-scale screening of rare genetic variants in humans reveals frequent splicing disruptions

bioRxiv
2017 | Journal article
Source: Self-asserted source
Daniel B. Goodman

Millstone: software for multiplex microbial genome analysis and engineering

Genome biology
2017 | Journal article
Source: Self-asserted source
Daniel B. Goodman

Optimizing complex phenotypes through model-guided multiplex genome engineering

Genome biology
2017 | Journal article
Source: Self-asserted source
Daniel B. Goodman

Many rare genetic variants have unrecognized large-effect disruptions to exon recognition

2017-10-08 | Preprint
Contributors: Rocky Cheung; Kimberly D. Insigne; David Yao; Christina P. Burghard; Eric M. Jones; Daniel B. Goodman; Sriram Kosuri
Source: check_circle
Crossref

Design, synthesis, and testing toward a 57-codon genome.

Science
2016 | Journal article
Source: Self-asserted source
Daniel B. Goodman

DNAplotlib: programmable visualization of genetic designs and associated data

ACS synthetic biology
2016 | Journal article
Source: Self-asserted source
Daniel B. Goodman

Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli

Proceedings of the National Academy of Sciences
2016 | Journal article
Source: Self-asserted source
Daniel B. Goodman

Engineering and optimising deaminase fusions for genome editing

Nature communications
2016 | Journal article
Source: Self-asserted source
Daniel B. Goodman

Genome Editing With Targeted Deaminases

bioRxiv
2016 | Journal article
Source: Self-asserted source
Daniel B. Goodman

Understanding genetic systems through multiplexed design, synthesis, and measurement

2016 | Dissertation or Thesis
Source: Self-asserted source
Daniel B. Goodman

Rational optimization of tolC as a powerful dual selectable marker for genome engineering

Nucleic Acids Research
2014 | Journal article
Source: Self-asserted source
Daniel B. Goodman

Composability of regulatory sequences controlling transcription and translation in Escherichia coli

Proceedings of the National Academy of Sciences
2013 | Journal article
Source: Self-asserted source
Daniel B. Goodman

Genome-wide Codon Replacement Using Synthetic Oligonucleotides and Engineered Conjugation

Genome Engineering Technologies to Change the Genetic Code
2013 | Journal article
Source: Self-asserted source
Daniel B. Goodman

Genomically recoded organisms expand biological functions

Science
2013 | Journal article
Source: Self-asserted source
Daniel B. Goodman

Causes and Effects of N-Terminal Codon Bias in Bacterial Genes

Science
2013-10 | Journal article
Part of ISSN: 0036-8075
Contributors: D. B. Goodman; G. M. Church; S. Kosuri
Source: Self-asserted source
Daniel B. Goodman via Crossref Metadata Search

Precise Manipulation of Chromosomes in Vivo Enables Genome-Wide Codon Replacement

Science
2011-07 | Journal article
Contributors: F. J. Isaacs; P. A. Carr; H. H. Wang; M. J. Lajoie; B. Sterling; L. Kraal; A. C. Tolonen; T. A. Gianoulis; D. B. Goodman; N. B. Reppas et al.
Source: Self-asserted source
Daniel B. Goodman via Crossref Metadata Search

Product length and dye choice and and detection chemistry in the bead-emulsion amplification of millions of single DNA molecules in parallel

Analytical Chemistry
2009 | Journal article
Source: Self-asserted source
Daniel B. Goodman

Comparative proteogenomics: combining mass spectrometry and comparative genomics to analyze multiple genomes

Genome research
2008 | Journal article
Source: Self-asserted source
Daniel B. Goodman

Baculovirus Phylogeny Based on Genome Rearrangements

Comparative Genomics
2007 | Other
Part of ISSN: 0302-9743
Contributors: Daniel Goodman; Noah Ollikainen; Chris Sholley
Source: Self-asserted source
Daniel B. Goodman via Crossref Metadata Search

Automated multiplexed multidensity microfluidic (M/sup 3/) cell sensing based on electrical gain measurements

2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology
2005 | Conference paper
Source: Self-asserted source
Daniel B. Goodman

Automated multiplexed multidensity microfluidic (M/sup 3/) cell sensing based on electrical gain measurements

Microtechnology in Medicine and Biology, 2005. 3rd IEEE/EMBS Special Topic Conference on
2005 | Conference paper
Source: Self-asserted source
Daniel B. Goodman

Nanofluidic channel engineering using laminar flow layer-by-layer deposition of polyelectrolytes.

ASME Integrated Nanosystems & Nanotechnology Showcase
2004 | Conference paper
Source: Self-asserted source
Daniel B. Goodman

Peer review (3 reviews for 3 publications/grants)

Review activity for Journal for immunotherapy of cancer. (1)
Review activity for Nature biomedical engineering. (1)
Review activity for Science advances. (1)