Personal information

Activities

Employment (1)

CRCM/Inserm/Cnrs/AMU: Marseille, FR

2012 to present | DR1 CNRS (epigenetic factors in hematopoiesis)
Employment
Source: Self-asserted source
Estelle Duprez

Education and qualifications (3)

harvard institute of medicine: Boston, US

1999-10-01 to 2002-04-01 | post-doc (hematology)
Education
Source: Self-asserted source
Estelle Duprez

Cancer Research UK: London, London, GB

1996-06-01 to 1997-12-01 | Post-doc
Education
Source: Self-asserted source
Estelle Duprez

Hôpital Saint-Louis: Paris, Île-de-France, FR

1992-09-01 to 1995-12-01 | PhD (Centre hayem)
Education
Source: Self-asserted source
Estelle Duprez

Works (38)

Predictive modelling of Acute Promyelocytic Leukaemia resistance to Retinoic Acid therapy

2025-01-09 | Other
Contributors: José Sanchez-villanueva; Lia N'Guyen; Mathilde Poplineau; Estelle Duprez; Elisabeth Remy; Denis Thieffry
Source: check_circle
Crossref

Direct presentation of inflammation-associated self-antigens by thymic innate-like T cells induces elimination of autoreactive CD8+ thymocytes

Nature Immunology
2024-08 | Journal article
Contributors: Yuanyuan You; Josefine Dunst; Kewei Ye; Patrick A. Sandoz; Annika Reinhardt; Inga Sandrock; Natalia R. Comet; Rupak Dey Sarkar; Emily Yang; Estelle Duprez et al.
Source: check_circle
Crossref

Logical modelling of myelofibrotic microenvironment predicts dysregulated progenitor stem cell crosstalk

BioSystems
2023-09 | Journal article
Contributors: S.P. Chapman; E. Duprez; Elisabeth Remy
Source: Self-asserted source
Estelle Duprez via HAL

A novel Boolean network inference strategy to model early hematopoiesis aging

Computational and Structural Biotechnology Journal
2022 | Journal article
Contributors: Léonard Hérault; Mathilde Poplineau; Estelle Duprez; Élisabeth Remy
Source: Self-asserted source
Estelle Duprez via HAL

Single Cell Transcriptomics to Understand HSC Heterogeneity and Its Evolution upon Aging

Cells
2022-10-04 | Journal article
Contributors: Léonard Hérault; Mathilde Poplineau; Elisabeth Remy; Estelle Duprez
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Crossref
grade
Preferred source (of 2)‎

Single-cell multi-omics analyses reveal EZH2 as a main driver of retinoic acid resistance in PLZF-RARA leukemia

2022-03-29 | Working paper
Contributors: M. Poplineau; N. Platet; A. Mazuel; L. Hérault; S. Koide; W. Kuribayashi; N. Carbuccia; L. N’guyen; J. Vernerey; M. Oshima et al.
Source: Self-asserted source
Estelle Duprez via HAL

Pharmacologic Reduction of Mitochondrial Iron Triggers a Noncanonical BAX/BAK-Dependent Cell Death

Cancer Discovery
2022-03-01 | Journal article
Contributors: Sylvain Garciaz; Andrew Guirguis; Sebastian Müller; Fiona Brown; Yih-Chih Chan; Ali Motazedian; Caitlin Rowe; James Kuzich; Kah Lok Chan; Kevin Tran et al.
Source: Self-asserted source
Estelle Duprez via HAL

SC-RNA-seq assisted synthesis of a Boolean network to model early haematopoiesis aging

2022-02-12 | Working paper
Contributors: Léonard Hérault; Mathilde Poplineau; Estelle Duprez; Elisabeth Remy
Source: Self-asserted source
Estelle Duprez via HAL

Single-cell RNA-seq reveals a concomitant delay in differentiation and cell cycle of aged hematopoietic stem cells

BMC Biology
2021-12 | Journal article
Contributors: Léonard Hérault; Mathilde Poplineau; Adrien Mazuel; Nadine Platet; Élisabeth Remy; Estelle Duprez
Source: check_circle
Crossref

Mining old transcriptomes to predict HSC age

Blood
2021-08-12 | Journal article
Contributors: Mathilde Poplineau; Estelle Duprez
Source: check_circle
Crossref

Single-cell RNA-seq reveals a concomitant delay in differentiation and cell cycle of aged hematopoietic stem cell

2020-06-18 | Preprint
Contributors: Léonard Hérault; Mathilde Poplineau; Adrien Mazuel; Nadine Platet; Élisabeth Remy; Estelle Duprez
Source: check_circle
Crossref

New Insights into PLZF/Rara Mechanism during APL Onset: EZH2 on the Road

Blood
2019-11-13 | Journal article
Part of ISSN: 0006-4971
Part of ISSN: 1528-0020
Source: Self-asserted source
Estelle Duprez

Epigenetic down-regulation of the HIST1 locus predicts better prognosis in acute myeloid leukemia with NPM1 mutation.

Clinical epigenetics
2019-10-12 | Journal article
Source: Self-asserted source
Estelle Duprez

PLZF limits enhancer activity during hematopoietic progenitor aging

Nucleic Acids Research
2019-05-21 | Journal article
Contributors: Mathilde Poplineau; Julien Vernerey; Nadine Platet; Lia N’guyen; Léonard Hérault; Michela Esposito; Andrew J Saurin; Christel Guilouf; Atsushi Iwama; Estelle Duprez
Source: check_circle
Crossref

Nidogen-1 Contributes to the Interaction Network Involved in Pro-B Cell Retention in the Peri-sinusoidal Hematopoietic Stem Cell Niche.

Cell reports
2019-03-01 | Journal article
Source: Self-asserted source
Estelle Duprez

TP53INP1 deficiency maintains murine B lymphopoiesis in aged bone marrow through redox-controlled IL-7R/STAT5 signaling

Proceedings of the National Academy of Sciences
2019-01-02 | Journal article
Contributors: Bochra Zidi; Christelle Vincent-Fabert; Laurent Pouyet; Marion Seillier; Amelle Vandevelde; Prudence N’guessan; Mathilde Poplineau; Geoffrey Guittard; Stéphane J. C. Mancini; Estelle Duprez et al.
Source: check_circle
Crossref

Regulation of the positive transcriptional effect of PLZF through a non-canonical EZH2 activity.

Nucleic acids research
2018-04-01 | Journal article
Source: Self-asserted source
Estelle Duprez

[The biological complexity of Polycomb group proteins: the case of EZH2].

Medecine sciences : M/S
2017-05-01 | Journal article
Source: Self-asserted source
Estelle Duprez

The cryptic IRF2BP2-RARA fusion transforms hematopoietic stem/progenitor cells and induces retinoid-sensitive acute promyelocytic leukemia.

Leukemia
2016-11-22 | Journal article
Source: Self-asserted source
Estelle Duprez

PLZF mutation alters mouse hematopoietic stem cell function and cell cycle progression.

Blood
2016-03-03 | Journal article
Source: Self-asserted source
Estelle Duprez

The BMI1 polycomb protein represses cyclin G2-induced autophagy to support proliferation in chronic myeloid leukemia cells.

Leukemia
2015-04-30 | Journal article
Source: Self-asserted source
Estelle Duprez

Downregulation of the Wnt inhibitor CXXC5 predicts a better prognosis in acute myeloid leukemia.

Blood
2015-03-24 | Journal article
Source: Self-asserted source
Estelle Duprez

Site- and allele-specific polycomb dysregulation in T-cell leukaemia.

Nature communications
2015-01-23 | Journal article
Source: Self-asserted source
Estelle Duprez

PcG methylation of the HIST1 cluster defines an epigenetic marker of acute myeloid leukemia.

Leukemia
2014-12-08 | Journal article
Source: Self-asserted source
Estelle Duprez

Epigenetics in focus: pathogenesis of myelodysplastic syndromes and the role of hypomethylating agents.

Critical reviews in oncology/hematology
2013-07-07 | Journal article
Source: Self-asserted source
Estelle Duprez

A hypomorphic mutation in the Gfi1 transcriptional repressor results in a novel form of neutropenia.

European journal of immunology
2012-09-01 | Journal article
Source: Self-asserted source
Estelle Duprez

Characterisation of genome-wide PLZF/RARA target genes.

PloS one
2011-09-20 | Journal article
Source: Self-asserted source
Estelle Duprez

MafB Restricts M-CSF-Dependent Myeloid Commitment Divisions of Hematopoietic Stem Cells

Cell
2009-07 | Journal article
Part of ISSN: 0092-8674
Source: Self-asserted source
Estelle Duprez

The PRC1 Polycomb group complex interacts with PLZF/RARA to mediate leukemic transformation.

Genes & Development
2009-05-01 | Journal article
Source: Self-asserted source
Estelle Duprez

Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation.

Blood
2005-05-24 | Journal article
Source: Self-asserted source
Estelle Duprez

A new role for C/EBPbeta in acute promyelocytic leukemia.

Cell Cycle
2004-04-01 | Journal article
Source: Self-asserted source
Estelle Duprez

C/EBPbeta: a major PML-RARA-responsive gene in retinoic acid-induced differentiation of APL cells.

The EMBO journal
2003-11-01 | Journal article
Source: Self-asserted source
Estelle Duprez

Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment, and As2O3-induced PML or PML/retinoic acid receptor alpha degradation.

The Journal of experimental medicine
2001-06-01 | Journal article
Source: Self-asserted source
Estelle Duprez

HPC3 is a new human polycomb orthologue that interacts and associates with RING1 and Bmi1 and has transcriptional repression properties.

The Journal of biological chemistry
2000-09-01 | Journal article
Source: Self-asserted source
Estelle Duprez

A mutated PML/RARA found in the retinoid maturation resistant NB4 subclone, NB4-R2, blocks RARA and wild-type PML/RARA transcriptional activities.

Leukemia
2000-02-01 | Journal article
Source: Self-asserted source
Estelle Duprez

JEM-1, a novel nuclear co-factor: localisation and functional interaction with AP-1.

Leukemia
1999-12-01 | Journal article
Source: Self-asserted source
Estelle Duprez

Identification of the t(15;17) in AML FAB types other than M3: evaluation of the role of molecular screening for the PML/RARalpha rearrangement in newly diagnosed AML. The Medical Research Council (MRC) Adult Leukaemia Working Party.

British journal of haematology
1999-04-01 | Journal article
Source: Self-asserted source
Estelle Duprez

Surface residue mutations of the PML RING finger domain alter the formation of nuclear matrix-associated PML bodies.

Journal of cell science
1997-09-01 | Journal article
PMID: 9378769
Source: Self-asserted source
Estelle Duprez

Peer review (2 reviews for 2 publications/grants)

Review activity for Clinical epigenetics (1)
Review activity for Nature communications (1)