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Employment (2)

Shenzhen Bay Laboratory: Shenzhen, Guangdong, CN

2020-03-16 to present | Asistant professor
Employment
Source: Self-asserted source
Rui WANG

Peking University Shenzhen Graduate School: Nanshan, Shenzhen, CN

2011-02-01 to 2012-11-30 | Research Associate (Chemical biology&biotechnology)
Employment
Source: Self-asserted source
Rui WANG

Education and qualifications (1)

Chinese University of Hong Kong: New Territories, Hong Kong, HK

2013-08-01 to 2016-09-30 | phd (Chemistry)
Education
Source: Self-asserted source
Rui WANG

Works (46)

A blood-based multi-omic landscape for the molecular characterization of kidney stone disease

Molecular Omics
2024 | Journal article
DOI: 10.1039/D3MO00261F
Contributors: Weibing Pan‡; Tianwei Yun; Xin Ouyang; Zhijun Ruan; Tuanjie Zhang; Yuhao An; Rui Wang; Peng Zhu
Source: check_circle
Crossref

A pyridinium-based strategy for lysine-selective protein modification and chemoproteomic profiling in live cells

Chemical Science
2024 | Journal article
DOI: 10.1039/D3SC05766F
Contributors: Chuan Wan; Dongyan Yang; Chunli Song; Mingchan Liang; Yuhao An; Chenshan Lian; Chuan Dai; Yuxin Ye; Feng Yin; Rui Wang et al.
Source: check_circle
Crossref

Covalent PROTAC design method based on a sulfonyl pyridone probe

Chemical Communications
2024 | Journal article
DOI: 10.1039/D3CC05127G
Contributors: Qinhong Luo; Yaqi Wang; Zhanfeng Hou; Huiting Liang; Licheng Tu; Yun Xing; Chuan Wan; Jianbo Liu; Rui Wang; Lizhi Zhu et al.
Source: check_circle
Crossref

β-Carbonyl sulfonium enables cysteine-specific bioconjugation for activity-based protein profiling in live cells

Chemical Communications
2024 | Journal article
DOI: 10.1039/D4CC00295D
Contributors: Chuan Wan; Dongyan Yang; Xiaochun Guo; Tuanjie Zhang; Zhijun Ruan; Chuan Dai; Yun Xing; Feng Yin; Rui Wang; Zigang Li
Source: check_circle
Crossref

Tunable Activated Esters Enable Lysine-Selective Protein Labeling and Profiling

Analytical Chemistry
2024-11-19 | Journal article
DOI: 10.1021/acs.analchem.4c02215
Contributors: Chuan Wan; Dongyan Yang; Yuhao An; Lingwei Kong; Ziyuan Zhou; Li Tang; Zhe Zhang; Yaohong Dai; Rui Wang
Source: check_circle
Crossref

Engineered human serum albumin for mapping drug fluctuations: Generatation of pseudo-fluorescent proteins by covalently coupling dyes for probing tamoxifen in vitro, in cellulo, and in vivo

Chemical Engineering Journal
2024-03 | Journal article
DOI: 10.1016/j.cej.2024.149484
Contributors: Xueting Wang; Xianwen Wang; Rui Wang; Xueao Wang; Zheng Li; Yanli Yang; Hai-Liang Zhu; Yong Qian
Source: check_circle
Crossref

Dynamic Metabolons Using Stimuli-Responsive Protein Cages

Journal of the American Chemical Society
2024-03-13 | Journal article
DOI: 10.1021/jacs.3c12876
Contributors: Wei Kang; Xiao Ma; Huawei Zhang; Juncai Ma; Chunxue Liu; Jiani Li; Hanhan Guo; Daping Wang; Rui Wang; Bo Li et al.
Source: check_circle
Crossref

Exploring the Binding Interaction Between Phosphotyrosine Peptides and SH2 Domains by Proximal Crosslinking

Methods in Molecular Biology
2023 | Book chapter
DOI: 10.1007/978-1-0716-3393-9_14
Part of ISBN: 9781071633922
Part of ISBN: 9781071633939
Part of ISSN: 1064-3745
Part of ISSN: 1940-6029
Contributors: Rui Wang; Yishu Bao; Jiang Xia
Source: Self-asserted source
Rui WANG

The thiol-sulfoxonium ylide photo-click reaction for bioconjugation

Chemical Science
2023 | Journal article
DOI: 10.1039/d2sc05650j
Part of ISSN: 2041-6520
Part of ISSN: 2041-6539
Contributors: Chuan Wan; Zhanfeng Hou; Dongyan Yang; Ziyuan Zhou; Hongkun Xu; Yuena Wang; Chuan Dai; Mingchan Liang; Jun Meng; Jiean Chen et al.
Source: Self-asserted source
Rui WANG

Pyridinium-Based Strategy for a Bioorthogonal Conjugation-Assisted Purification Method for Profiling Cell Surface Proteome

Analytical Chemistry
2023-11-21 | Journal article
DOI: 10.1021/acs.analchem.3c04279
Part of ISSN: 0003-2700
Part of ISSN: 1520-6882
Contributors: Chuan Dai; Xiaochun Guo; Zhuoheng Pan; Chuan Wan; Dongyan Yang; Yongli Li; Chenshan Lian; Yuhao An; Tuanjie Zhang; Fadeng Yang et al.
Source: Self-asserted source
Rui WANG

Development of Lysine Crotonyl‐Mimic Probe to Covalently Identify H3K27Cr Interacting Proteins

Chemistry – A European Journal
2023-11-08 | Journal article
DOI: 10.1002/chem.202301624
Part of ISSN: 0947-6539
Part of ISSN: 1521-3765
Contributors: Xiaochun Guo; Yuena Wang; Yuhao An; Zhihong Liu; Jianbo Liu; Jiaxin Chen; Mei‐miao Zhan; Mingcha Liang; Zhanfeng Hou; Chuan Wan et al.
Source: Self-asserted source
Rui WANG

Selective Protein of Interest Degradation through the Split-and-Mix Liposome Proteolysis Targeting Chimera Approach

Journal of the American Chemical Society
2023-10-11 | Journal article
DOI: 10.1021/jacs.3c05948
Part of ISSN: 0002-7863
Part of ISSN: 1520-5126
Contributors: Chunli Song; Zijun Jiao; Zhanfeng Hou; Rui Wang; Chenshan Lian; Yun Xing; Qinhong Luo; Yuhao An; Fenfang Yang; Yuechen Wang et al.
Source: Self-asserted source
Rui WANG

Wnt3a signaling with serum supply induces replication stress in cultured cells

Biochemistry and Biophysics Reports
2023-09 | Journal article
DOI: 10.1016/j.bbrep.2023.101499
Part of ISSN: 2405-5808
Contributors: Ying Wang; Rui Wang; Haiying Ma; Mengsu Yang; Zigang Li; Liang ZHANG
Source: Self-asserted source
Rui WANG

Comparative Analysis of Transcriptome and Proteome Revealed the Common Metabolic Pathways Induced by Prevalent ESBL Plasmids in Escherichia coli

International Journal of Molecular Sciences
2023-09-12 | Journal article
DOI: 10.3390/ijms241814009
Part of ISSN: 1422-0067
Contributors: Chuan Huang; Hoa-Quynh Pham; Lina ZHU; Rui Wang; Oi-Kwan Law; Shu-Ling Lin; Qi-Chang Nie; Liang Zhang; Xin Wang; Terrence chi kong LAU
Source: Self-asserted source
Rui WANG

Bioorthogonal Fluoride-Responsive Azide and Alkynyl Pyridinium Click Cycloaddition <i>in Vitro</i> and in Live Cells

Organic Letters
2023-06-16 | Journal article
DOI: 10.1021/acs.orglett.3c01403
Part of ISSN: 1523-7060
Part of ISSN: 1523-7052
Contributors: Zhanfeng Hou; Chuan Wan; Yun Xing; Xiaochun Guo; Yaping Zhang; Rui Wang; Feng Yin; Ming-Sheng Xie
Source: Self-asserted source
Rui WANG

Chemical protein synthesis elucidates key modulation mechanism of the tyrosine-O-sulfation in inducing strengthened inhibitory activity of hirudin

Chinese Chemical Letters
2023-05 | Journal article
DOI: 10.1016/j.cclet.2022.107806
Contributors: Ye Yang; Mingchan Liang; Rui Wang; Chunmao He
Source: check_circle
Crossref

Targeting UBE2C for degradation by bioPROTACs based on bacterial E3 ligase

Chinese Chemical Letters
2023-04 | Journal article
DOI: 10.1016/j.cclet.2022.08.012
Contributors: Jinpeng Wang; Min Zhang; Susheng Liu; Zhipeng He; Rui Wang; Minchan Liang; Yuhao An; Chenran Jiang; Chunli Song; Zigong Ning et al.
Source: check_circle
Crossref

Flavin catalyzed desulfurization of peptides and proteins in aqueous media

Organic &amp; Biomolecular Chemistry
2022 | Journal article
DOI: 10.1039/d2ob00641c
Part of ISSN: 1477-0520
Part of ISSN: 1477-0539
Source: Self-asserted source
Rui WANG

Histidine-Specific bioconjugation via visible-light-promoted thioacetal activation

Chemical Science
2022 | Journal article
DOI: 10.1039/d2sc02353a
Part of ISSN: 2041-6520
Part of ISSN: 2041-6539
Source: Self-asserted source
Rui WANG

The phosphorylation and dephosphorylation switch of VCP/p97 regulates the architecture of centrosome and spindle

Cell Death & Differentiation
2022-10 | Journal article
DOI: 10.1038/s41418-022-01000-4
Contributors: Kaiyuan Zhu; Yang Cai; Xiaotong Si; Zuodong Ye; Yuanzhu Gao; Chuang Liu; Rui Wang; Zhibin Ma; Huazhang Zhu; Liang Zhang et al.
Source: check_circle
Crossref

A Peptide-Based Ligand-Directed Chemistry Enables Protein Functionalization

Organic Letters
2022-10-07 | Journal article
DOI: 10.1021/acs.orglett.2c02974
Contributors: Yuena Wang; Rongtong Zhao; Chuan Wan; Xiaochun Guo; Fenfang Yang; Zhanfeng Hou; Rui Wang; Shuiming Li; Tiejian Feng; Feng Yin et al.
Source: check_circle
Crossref

A proximity-triggered strategy towards transferable PROTACs

CCS Chemistry
2022-06-22 | Journal article
DOI: 10.31635/ccschem.022.202201985
Part of ISSN: 2096-5745
Source: Self-asserted source
Rui WANG

Chemo-Selective Cys–Pen Disulfide for Proximity-Induced Cysteine Cross-Linking

ACS Chemical Biology
2022-03-18 | Journal article
DOI: 10.1021/acschembio.2c00083
Contributors: Mei-miao Zhan; Rui Wang; Zhihong Liu; Na Liu; Yuxin Ye; Mingchan Liang; Yichi Zhang; Chenran Jiang; Feng Yin; Zigang Li
Source: check_circle
Crossref

Low-Toxicity Sulfonium-Based Probes for Cysteine-Specific Profiling in Live Cells

Analytical Chemistry
2022-03-15 | Journal article
DOI: 10.1021/acs.analchem.1c05129
Contributors: Rui Wang; Dongyan Yang; Tian Tian; Yuhao An; Chuan Wan; Qi Chang; Mingchan Liang; Zhanfeng Hou; Ying Wang; Liang Zhang et al.
Source: check_circle
Crossref

Quantitative proteomics reveals differential immunoglobulin-associated proteome (IgAP) in patients of acute myocardial infarction and chronic coronary syndromes

Journal of Proteomics
2022-02 | Journal article
DOI: 10.1016/j.jprot.2021.104449
Part of ISSN: 1874-3919
Source: Self-asserted source
Rui WANG

Sulfonium Triggered Alkyne–Azide Click Cycloaddition

Organic Letters
2022-02-25 | Journal article
DOI: 10.1021/acs.orglett.2c00021
Contributors: Zhanfeng Hou; Yuena Wang; Chuan Wan; Lijuan Song; Rui Wang; Xiaochun Guo; Dongyan Yang; Yaping Zhang; Xuan Qin; Ziyuan Zhou et al.
Source: check_circle
Crossref

Design and Evaluation of a Novel Peptide–Drug Conjugate Covalently Targeting SARS-CoV-2 Papain-like Protease

Journal of Medicinal Chemistry
2022-01-13 | Journal article
DOI: 10.1021/acs.jmedchem.1c02022
Contributors: Na Liu; Yichi Zhang; Yingshou Lei; Rui Wang; Meimiao Zhan; Jianbo Liu; Yuhao An; Yaoqi Zhou; Jian Zhan; Feng Yin et al.
Source: check_circle
Crossref

Identification of an autoinhibitory, mitophagy-inducing peptide derived from the transmembrane domain of USP30

Autophagy
2022-01-06 | Journal article
DOI: 10.1080/15548627.2021.2022360
Part of ISSN: 1554-8627
Part of ISSN: 1554-8635
Source: Self-asserted source
Rui WANG

Electrophilic Sulfonium-Promoted Peptide and Protein Amidation in Aqueous Media

Organic Letters
2021-12-30 | Journal article
DOI: 10.1021/acs.orglett.1c04017
Part of ISSN: 1523-7060
Part of ISSN: 1523-7052
Source: Self-asserted source
Rui WANG

Proximity-induced amino-yne reaction for selective MDM4 conjugation via propargylated sulfonium

Chinese Chemical Letters
2021-11 | Journal article
DOI: 10.1016/j.cclet.2021.04.015
Part of ISSN: 1001-8417
Source: Self-asserted source
Rui WANG

A bifunctional vinyl-sulfonium tethered peptide induced by thio-Michael-type addition reaction

Chinese Chemical Letters
2021-09 | Journal article
DOI: 10.1016/j.cclet.2021.09.071
Part of ISSN: 1001-8417
Source: Self-asserted source
Rui WANG

Vacuolin-1 inhibits endosomal trafficking and metastasis via CapZβ

Oncogene
2021-03-10 | Journal article
DOI: 10.1038/s41388-021-01662-3
Part of ISSN: 0950-9232
Part of ISSN: 1476-5594
Source: Self-asserted source
Rui WANG

Intramolecular methionine alkylation constructs sulfonium tethered peptides for protein conjugation

Chemical Communications
2020 | Journal article
DOI: 10.1039/D0CC00377H
Contributors: Yang Li; Chenshan Lian; Zhanfeng Hou; Dongyuan Wang; Rui Wang; Chuan Wan; Wanjin Zhong; Rongtong Zhao; Yuena Wang; Shuiming Li et al.
Source: check_circle
Crossref

Correction for Zhang et al., “Pseudomonas aeruginosa Regulatory Protein AnvM Controls Pathogenicity in Anaerobic Environments and Impacts Host Defense”

mBio
2020-10-27 | Journal article
DOI: 10.1128/mbio.02368-20
Part of ISSN: 2161-2129
Part of ISSN: 2150-7511
Source: Self-asserted source
Rui WANG

Host–Guest Protein Assembly for Affinity Purification of Methyllysine Proteomes

Analytical Chemistry
2020-07-07 | Journal article
DOI: 10.1021/acs.analchem.0c01643
Contributors: Linting Li; Min Liu; Ludan Yue; Rui Wang; Ning Zhang; Yujie Liang; Liang Zhang; Lixin Cheng; Jiang Xia; Ruibing Wang
Source: check_circle
Crossref

Dissecting the novel partners of nuclear c-Raf and its role in all-trans retinoic acid (ATRA)-induced myeloblastic leukemia cells differentiation

Experimental Cell Research
2020-04 | Journal article
DOI: 10.1016/j.yexcr.2020.111989
Part of ISSN: 0014-4827
Source: Self-asserted source
Rui WANG
grade
Preferred source (of 2)‎

Safeguarding intestine cells against enteropathogenic Escherichia coli by intracellular protein reaction, a preventive antibacterial mechanism

Proceedings of the National Academy of Sciences
2020-03-10 | Journal article
DOI: 10.1073/pnas.1914567117
Part of ISSN: 0027-8424
Part of ISSN: 1091-6490
Source: Self-asserted source
Rui WANG

A sulfonium tethered peptide ligand rapidly and selectively modifies protein cysteine in vicinity

Chemical Science
2019 | Journal article
DOI: 10.1039/c9sc00034h
Part of ISSN: 2041-6520
Part of ISSN: 2041-6539
Source: Self-asserted source
Rui WANG
grade
Preferred source (of 2)‎

Chemical Probes Reveal Sirt2’s New Function as a Robust “Eraser” of Lysine Lipoylation

Journal of the American Chemical Society
2019-11-20 | Journal article
DOI: 10.1021/jacs.9b06913
Part of ISSN: 0002-7863
Part of ISSN: 1520-5126
Source: Self-asserted source
Rui WANG

Synthetic Multienzyme Complexes, Catalytic Nanomachineries for Cascade Biosynthesis In Vivo

ACS Nano
2019-09-24 | Journal article
DOI: 10.1021/acsnano.9b03631
Part of ISSN: 1936-0851
Part of ISSN: 1936-086X
Source: Self-asserted source
Rui WANG

Pseudomonas aeruginosa Regulatory Protein AnvM Controls Pathogenicity in Anaerobic Environments and Impacts Host Defense

mBio
2019-07-23 | Journal article
DOI: 10.1128/mbio.01362-19
Part of ISSN: 2150-7511
Source: Self-asserted source
Rui WANG

The ribosomal maturation factor P from Mycobacterium smegmatis facilitates the ribosomal biogenesis by binding to the small ribosomal protein S12

Journal of Biological Chemistry
2019-01-04 | Journal article
DOI: 10.1074/jbc.ra118.002298
Part of ISSN: 0021-9258
Part of ISSN: 1083-351X
Source: Self-asserted source
Rui WANG

Affinity Purification of Methyllysine Proteome by Site-Specific Covalent Conjugation

Analytical Chemistry
2018-12-04 | Journal article
DOI: 10.1021/acs.analchem.8b02796
Part of ISSN: 0003-2700
Part of ISSN: 1520-6882
Source: Self-asserted source
Rui WANG

Reverse Binding Mode of Phosphotyrosine Peptides with SH2 Protein

Biochemistry
2018-09-04 | Journal article
DOI: 10.1021/acs.biochem.8b00677
Part of ISSN: 0006-2960
Part of ISSN: 1520-4995
Source: Self-asserted source
Rui WANG

Targeted Covalent Inhibition of Grb2–Sos1 Interaction through Proximity-Induced Conjugation in Breast Cancer Cells

Molecular Pharmaceutics
2017-05 | Journal article
DOI: 10.1021/acs.molpharmaceut.6b00952
Part of ISSN: 1543-8384
Part of ISSN: 1543-8392
Source: Self-asserted source
Rui WANG

PDZ-Reactive Peptide Activates Ephrin-B Reverse Signaling and Inhibits Neuronal Chemotaxis

ACS Chemical Biology
2016-01-15 | Journal article
DOI: 10.1021/acschembio.5b00889
Part of ISSN: 1554-8929
Part of ISSN: 1554-8937
Source: Self-asserted source
Rui WANG

Peer review (4 reviews for 3 publications/grants)

Review activity for ACS medicinal chemistry letters. (1)
Review activity for Analytical chemistry. (1)
Review activity for International journal of biological macromolecules. (2)
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