Personal information

Activities

Works (22)

Structural Congeners of Izenamides Responsible for Cathepsin D Inhibition: Insights from Synthesis-Derived Elucidation

Marine Drugs
2023-04 | Journal article | Author
Contributors: Hyun Su Kim; Hyejin Kong; Taewoo Kim; Changjin Lim; Seungbeom Lee; Seok-Ho Kim; Young-Ger Suh
Source: check_circle
Multidisciplinary Digital Publishing Institute

Antitumor Activity of Novel Signal Transducer and Activator of Transcription 3 Inhibitors on Retinoblastoma

Molecular pharmacology
2021 | Journal article
EID:

2-s2.0-85112124660

Part of ISSN: 15210111
Contributors: Jo, D.H.; Lee, S.; Bak, E.; Cho, C.S.; Han, Y.T.; Kim, K.; Suh, Y.-G.; Kim, J.H.
Source: Self-asserted source
Seungbeom Lee via Scopus - Elsevier

Discovery of novel potent migrastatic Thiazolo[5,4-b]pyridines targeting Lysyl-tRNA synthetase (KRS) for treatment of Cancer metastasis

European Journal of Medicinal Chemistry
2021 | Journal article
EID:

2-s2.0-85103733602

Part of ISSN: 17683254 02235234
Contributors: Lee, S.; Kwon, N.H.; Seo, B.; Lee, J.Y.; Cho, H.Y.; Kim, K.; Kim, H.S.; Jung, K.; Jeon, Y.H.; Kim, S. et al.
Source: Self-asserted source
Seungbeom Lee via Scopus - Elsevier

ERRγ ligand HPB2 upregulates BDNF-TrkB and enhances dopaminergic neuronal phenotype

Pharmacological Research
2021 | Journal article
EID:

2-s2.0-85099289538

Part of ISSN: 10961186 10436618
Contributors: Kim, H.I.; Lee, S.; Lim, J.; Chung, S.; Koo, T.-S.; Ji, Y.-G.; Suh, Y.-G.; Son, W.S.; Kim, S.-H.; Choi, H.J.
Source: Self-asserted source
Seungbeom Lee via Scopus - Elsevier

Recent advances in development of hetero-bivalent kinase inhibitors

European Journal of Medicinal Chemistry
2021 | Journal article
EID:

2-s2.0-85102351330

Part of ISSN: 17683254 02235234
Contributors: Lee, S.; Kim, J.; Jo, J.; Chang, J.W.; Sim, J.; Yun, H.
Source: Self-asserted source
Seungbeom Lee via Scopus - Elsevier

A Michael Acceptor Analogue, SKSI-0412, Down-Regulates Inflammation and Proliferation Factors through Suppressing Signal Transducer and Activator of Transcription 3 Signaling in IL-17A-Induced Human Keratinocyte

International Journal of Molecular Sciences
2021-08 | Journal article | Author
Contributors: A-Ram Kim; Seungbeom Lee; Jung U Shin; seung hui seok; Young-Ger Suh; DONG HYUN KIM
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

2-Aminophenylpyrimidines as Novel Inhibitors of Aminoacyl-tRNA Synthetase Interacting Multifunctional Protein 2 (AIMP2)-DX2 for Lung Cancer Treatment

Journal of Medicinal Chemistry
2020 | Journal article
EID:

2-s2.0-85084025682

Part of ISSN: 15204804 00222623
Contributors: Lee, S.; Kim, D.G.; Kim, K.; Kim, T.; Lim, S.; Kong, H.; Kim, S.; Suh, Y.-G.
Source: Self-asserted source
Seungbeom Lee via Scopus - Elsevier

A novel small molecule STAT3 inhibitor SLSI-1216 suppresses proliferation and tumor growth of triple-negative breast cancer cells through apoptotic induction

Biochemical Pharmacology
2020 | Journal article
EID:

2-s2.0-85086650170

Part of ISSN: 18732968 00062952
Contributors: Park, S.K.; Byun, W.S.; Lee, S.; Han, Y.T.; Jeong, Y.-S.; Jang, K.; Chung, S.-J.; Lee, J.; Suh, Y.-G.; Lee, S.K.
Source: Self-asserted source
Seungbeom Lee via Scopus - Elsevier

An electrophilic deguelin analogue inhibits stat3 signaling in h-ras-transformed human mammary epithelial cells: The cysteine 259 residue as a potential target

Biomedicines
2020 | Journal article
EID:

2-s2.0-85095693777

Part of ISSN: 22279059
Contributors: Hong, S.-J.; Kim, J.-T.; Kim, S.-J.; Cho, N.-C.; Kim, K.; Lee, S.; Suh, Y.-G.; Cho, K.-C.; Kim, K.P.; Surh, Y.-J.
Source: Self-asserted source
Seungbeom Lee via Scopus - Elsevier

Collective Syntheses of Guaiane Sesquiterpenes: Stereoselective Syntheses of (+)-Dysodensiol F, (+)-10β,14-Dihydroxy- allo-aromadendrane, and (-)-Dendroside C Aglycon

Journal of Organic Chemistry
2020 | Journal article
EID:

2-s2.0-85094644208

Part of ISSN: 15206904 00223263
Contributors: Kim, H.S.; Park, H.; Lim, J.; Lim, C.; Kim, T.; Lee, S.; Hur, J.; Sim, J.; Choi, H.J.; Suh, Y.-G.
Source: Self-asserted source
Seungbeom Lee via Scopus - Elsevier

Development and validation of analytical method for SH-1242 in the rat and mouse plasma by liquid chromatography/tandem mass spectrometry

Molecules
2020 | Journal article
EID:

2-s2.0-85078688431

Part of ISSN: 14203049
Contributors: Jeong, Y.-S.; Baek, M.; Lee, S.; Kim, M.-S.; Maeng, H.-J.; Lee, J.-H.; Suh, Y.-G.; Chung, S.-J.
Source: Self-asserted source
Seungbeom Lee via Scopus - Elsevier

Synthesis and Structure-Activity Relationships of Arylsulfonamides as AIMP2-DX2 Inhibitors for the Development of a Novel Anticancer Therapy

Journal of Medicinal Chemistry
2020 | Journal article
EID:

2-s2.0-85084092035

Part of ISSN: 15204804 00222623
Contributors: Sivaraman, A.; Kim, D.G.; Bhattarai, D.; Kim, M.; Lee, H.Y.; Lim, S.; Kong, J.; Goo, J.-I.; Shim, S.; Lee, S. et al.
Source: Self-asserted source
Seungbeom Lee via Scopus - Elsevier

15-Keto prostaglandin E<inf>2</inf> suppresses STAT3 signaling and inhibits breast cancer cell growth and progression

Redox Biology
2019 | Journal article
EID:

2-s2.0-85065893974

Part of ISSN: 22132317
Contributors: Lee, E.J.; Kim, S.-J.; Hahn, Y.-I.; Yoon, H.-J.; Han, B.; Kim, K.; Lee, S.; Kim, K.P.; Suh, Y.G.; Na, H.-K. et al.
Source: Self-asserted source
Seungbeom Lee via Scopus - Elsevier

Investigation of B,C-ring truncated deguelin derivatives as heat shock protein 90 (HSP90) inhibitors for use as anti-breast cancer agents

Bioorganic and Medicinal Chemistry
2019 | Journal article
EID:

2-s2.0-85062157105

Part of ISSN: 14643391 09680896
Contributors: Kim, H.S.; Hoang, V.-H.; Hong, M.; Chul Kim, K.; Ann, J.; Nguyen, C.-T.; Seo, J.H.; Choi, H.; Yong Kim, J.; Kim, K.-W. et al.
Source: Self-asserted source
Seungbeom Lee via Scopus - Elsevier

Conformation-Enabled Total Syntheses of Ohmyungsamycins A and B and Structural Revision of Ohmyungsamycin B

Angewandte Chemie - International Edition
2018 | Journal article
EID:

2-s2.0-85042234557

Part of ISSN: 15213773 14337851
Contributors: Hur, J.; Jang, J.; Sim, J.; Son, W.S.; Ahn, H.-C.; Kim, T.S.; Shin, Y.-H.; Lim, C.; Lee, S.; An, H. et al.
Source: Self-asserted source
Seungbeom Lee via Scopus - Elsevier

Novel Hypoxia-Inducible Factor 1α (HIF-1α) Inhibitors for Angiogenesis-Related Ocular Diseases: Discovery of a Novel Scaffold via Ring-Truncation Strategy

Journal of Medicinal Chemistry
2018 | Journal article
EID:

2-s2.0-85055034698

Part of ISSN: 15204804 00222623
Contributors: An, H.; Lee, S.; Lee, J.M.; Jo, D.H.; Kim, J.; Jeong, Y.-S.; Heo, M.J.; Cho, C.S.; Choi, H.; Seo, J.H. et al.
Source: Self-asserted source
Seungbeom Lee via Scopus - Elsevier

Total synthesis of (+)-brasilenyne: Via concise construction of an oxonane framework containing a 1,3- cis, cis -diene

Chemical Communications
2018 | Journal article
EID:

2-s2.0-85040603632

Part of ISSN: 1364548X 13597345
Contributors: Lim, C.; Ahn, J.; Sim, J.; Yun, H.; Hur, J.; An, H.; Jang, J.; Lee, S.; Suh, Y.-G.
Source: Self-asserted source
Seungbeom Lee via Scopus - Elsevier

Asymmetric Total Synthesis of (+)-Intricenyne via an Endocyclization Route to Oxocane Skeleton

Organic Letters
2017 | Journal article
EID:

2-s2.0-85038428681

Part of ISSN: 15237052 15237060
Contributors: Ahn, J.; Lim, C.; Yun, H.; Kim, H.S.; Kwon, S.; Lee, J.; Lee, S.; An, H.; Park, H.-G.; Suh, Y.-G.
Source: Self-asserted source
Seungbeom Lee via Scopus - Elsevier

Deguelin analogue SH-1242 inhibits Hsp90 activity and exerts potent anticancer efficacy with limited neurotoxicity

Cancer Research
2016 | Journal article
EID:

2-s2.0-84958171100

Part of ISSN: 15387445 00085472
Contributors: Lee, S.-C.; Min, H.-Y.; Choi, H.; Bae, S.Y.; Park, K.H.; Hyun, S.Y.; Lee, H.J.; Moon, J.; Park, S.-H.; Kim, J.Y. et al.
Source: Self-asserted source
Seungbeom Lee via Scopus - Elsevier

Identification of a novel circadian clock modulator controlling BMAL1 expression through a ROR/REV-ERB-response element-dependent mechanism

Biochemical and Biophysical Research Communications
2016 | Journal article
EID:

2-s2.0-84953637322

Part of ISSN: 10902104 0006291X
Contributors: Lee, J.; Lee, S.; Chung, S.; Park, N.; Son, G.H.; An, H.; Jang, J.; Chang, D.-J.; Suh, Y.-G.; Kim, K.
Source: Self-asserted source
Seungbeom Lee via Scopus - Elsevier

Total synthesis of (-)-deguelin via an iterative pyran-ring formation strategy

Chemical Communications
2015 | Journal article
EID:

2-s2.0-84929328705

Part of ISSN: 1364548X 13597345
Contributors: Lee, S.; An, H.; Chang, D.-J.; Jang, J.; Kim, K.; Sim, J.; Lee, J.; Suh, Y.-G.
Source: Self-asserted source
Seungbeom Lee via Scopus - Elsevier

Design, synthesis, and biological evaluation of novel deguelin-based heat shock protein 90 (HSP90) inhibitors targeting proliferation and angiogenesis

Journal of Medicinal Chemistry
2012 | Journal article
EID:

2-s2.0-84871647827

Part of ISSN: 00222623 15204804
Contributors: Chang, D.-J.; An, H.; Kim, K.-S.; Kim, H.H.; Jung, J.; Lee, J.M.; Kim, N.-J.; Han, Y.T.; Yun, H.; Lee, S. et al.
Source: Self-asserted source
Seungbeom Lee via Scopus - Elsevier

Peer review (1 review for 1 publication/grant)

Review activity for The international journal of biochemistry & cell biology. (1)