Personal information

United Kingdom

Biography

Daniel G. Bracewell is Professor of Bioprocess Analysis at the UCL Department of Biochemical Engineering. His notable contributions have significantly advanced our understanding of biological product purification, often through collaborations with industry leaders. He has authored over 100 peer-reviewed journal articles, many of which involve fruitful partnerships with esteemed institutions in Thailand, India, and the USA.

One particularly impactful project led to the creation of Puridify, a nanofiber adsorption technology company now owned by Cytiva. As the academic lead for the UCL-Cytiva Centre of Excellence, Daniel is at the forefront of pioneering efforts in bioprocessing. His current focus involves the development of cell-free / enzymatic manufacturing technologies, aimed at facilitating personalised cell and gene therapies.

Activities

Employment (3)

University College London: London, GB

Employment
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University College London

University College London: London, London, GB

2016-10-01 to present | Professor (Department of Biochemical Engineering)
Employment
Source: Self-asserted source
Daniel G. Bracewell

University College London: London, London, GB

2012-10-01 to 2016-09-30 | Reader (Biochemical Engineering)
Employment
Source: Self-asserted source
Daniel G. Bracewell

Funding (40)

Smart biomanufacturing for genomic medicines

2024-03-01 to 2029-02-28 | Grant
Engineering and Physical Sciences Research Council (Swindon, GB)
GRANT_NUMBER: EP/X025446/1
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard

Cryogenic electron microscopy-based understanding of viral vector heterogeneity to aide process development

2023-10-01 to 2027-09-30 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: 2879798
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard

Design of nanofibre based adsorbent for extracellular vesicle isolation

2023-10-01 to 2027-09-24 | Grant
Engineering and Physical Sciences Research Council (Swindon, GB)
GRANT_NUMBER: 2881719
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard

Manufacturing research hub for a sustainable future: Vaccines for pandemic preparedness

2023-09-01 to 2030-08-31 | Grant
Engineering and Physical Sciences Research Council (Swindon, GB)
GRANT_NUMBER: EP/X038181/1
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard

Prosperity Partnerships Call 5 Strategic Students Pall Europe and University College London

2023-08-25 to 2028-08-24 | Grant
Engineering and Physical Sciences Research Council (Swindon, GB)
GRANT_NUMBER: EP/Y528870/1
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard

The Future Vaccine Manufacturing Research Hub (Vax-Hub) - Additional Funding

2022-10-01 to 2023-03-31 | Grant
Engineering and Physical Sciences Research Council (Swindon, GB)
GRANT_NUMBER: EP/X03867X/1
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard

Visual identification, analysis and modelling of sterilising grade filtration for liposome enveloped products

2021-10-01 to 2025-09-30 | Grant
Engineering and Physical Sciences Research Council (Swindon, GB)
GRANT_NUMBER: 2596197
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard

A high throughput platform to capture process interactions in mAb downstream processing

2021-10-01 to 2025-09-26 | Grant
Engineering and Physical Sciences Research Council (Swindon, GB)
GRANT_NUMBER: 2585635
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard

Digital design and fabrication of advanced biopurification materials

2021-06-01 to 2024-05-31 | Grant
UK Research and Innovation (Swindon, GB)
GRANT_NUMBER: MR/W004399/1
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard

Chromatographic separations for mRNA therapeutics: developing platform process for a new therapeutic modality

2020-10-01 to 2025-09-27 | Grant
Engineering and Physical Sciences Research Council (Swindon, GB)
GRANT_NUMBER: 2424139
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard

3D measurement of fouling in membrane filtration: towards model based investigation and design

2020-10-01 to 2021-09-30 | Grant
Engineering and Physical Sciences Research Council (Swindon, GB)
GRANT_NUMBER: 2417227
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard

Nanofibre adsorbent design informed by mechanistic modelling of bioprocess performance

2020-09-28 to 2024-09-27 | Grant
Engineering and Physical Sciences Research Council (Swindon, GB)
GRANT_NUMBER: 2404769
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard

Big data analytics and advanced mathematical modelling to enhance chromatography performance

2019-10-01 to 2023-09-30 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: BB/T50841X/1
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard

Big data analytics and advanced mathematical modelling to enhance chromatography performance

2019-10-01 to 2023-09-22 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: 2247274
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard

Development of affinity ligands for antibody glycoform separations based on the Fc-gamma receptor

2019-10-01 to 2023-09-22 | Grant
Engineering and Physical Sciences Research Council (Swindon, GB)
GRANT_NUMBER: 2247017
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard

Evaluating the impacts of pumping stress on aggregate formation during Tangential Flow Filtration

2019-10-01 to 2023-09-22 | Grant
Engineering and Physical Sciences Research Council (Swindon, GB)
GRANT_NUMBER: 2247014
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard

The Future Vaccine Manufacturing Research Hub (Vax-Hub)

2018-03-31 to 2021-03-30 | Grant
Engineering and Physical Sciences Research Council (Swindon, GB)
GRANT_NUMBER: EP/R013756/1
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard

Specific exosomes as novel media component to enhance manufacturing cell lines.

2017-10-01 to 2022-04-24 | Grant
Natural Environment Research Council (Swindon, GB)
GRANT_NUMBER: 1916135
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard

Process development for recovery and purification of exosomes for regenerative therapy

2017-10-01 to 2022-03-24 | Grant
Natural Environment Research Council (Swindon, GB)
GRANT_NUMBER: 1926420
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard

GCRF establishment of biopharmaceutical and animal vaccine production capacity in Thailand and neighbouring South East Asian countries

2017-09-30 to 2021-12-31 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: BB/P02789X/1
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard

FUTURE TARGETED HEALTHCARE MANUFACTURING HUB

2017-01-01 to 2023-12-31 | Grant
Engineering and Physical Sciences Research Council (Swindon, GB)
GRANT_NUMBER: EP/P006485/1
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard

ULTRA - Ultra Low-cost Transferable Automated Platform for Vaccine Manufacturing

2016-11 to 2021-10 | Grant
Bill and Melinda Gates Foundation (WA, WA, US)
GRANT_NUMBER: OPP1154682
Source: Self-asserted source
Daniel G. Bracewell

Development and optimisation of downstream processing for next generation biotherapeutics

Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard
grade
Preferred source (of 2)‎

Determining biopharmaceutical critical quality signatures at the interface of upstream and downstream process development

2015-10-01 to 2019-09-30 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: 1632715
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard

Determining Biopharmaceutical Critical Quality Signatures at the interface of upstream and Downstream process development

2015-10-01 to 2019-09-30 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: BB/N503812/1
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard

Analytical Data Analysis for the Bioprocessing Industry

2015-10-01 to 2018-09-30 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: BB/N003950/1
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard

EPSRC Centre for Doctoral Training in Emergent Macromolecular Therapies (EMT): A National CDT linked to an EPSRC Centre for Innovative Manufacturing

Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard
grade
Preferred source (of 2)‎

Nanofibre scale-up and industrial validation - Industrial Biotechnology Catalyst Translation and Industrial Research Awards

Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard
grade
Preferred source (of 2)‎

13TSB_TIBio: Technology Inspired Innovation Bioscience - Puridify

2014-05-05 to 2015-11-05 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: BB/M004848/1
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard
grade
Preferred source (of 2)‎

Creation of a process understanding of chromatographic performance loss during biotherapeutic manufacture: A UK-India partnership

Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard
grade
Preferred source (of 3)‎

Centre for Nature Inspired Engineering (CNIE): Addressing Challenges in Sustainability and Scalable Manufacturing

2013-11-29 to 2018-11-28 | Grant
Engineering and Physical Sciences Research Council (Swindon, GB)
GRANT_NUMBER: EP/K038656/1
GRANT_NUMBER: EP/K038656/1
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard
grade
Preferred source (of 4)‎

US partnering on the use of neutron scattering to study aggregation in therapeutic proteins during manufacture and storage

Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard
grade
Preferred source (of 4)‎

BRIC DOCTORATE PROGRAMME - Understanding on-column protein aggregation and its impact on bioprocessing

2011-09-30 to 2015-09-29 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: BB/J003832/1
GRANT_NUMBER: BB/J003832/1
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard
grade
Preferred source (of 4)‎

Training for the next generation of bioprocessing leaders

2010-10-01 to 2014-09-30 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: BB/H015795/1
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard

Biochemical Engineering MSc

2010-10-01 to 2013-09-30 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: BB/H020632/1
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard

MRes in Synt0etic Biology

2010-10-01 to 2013-09-30 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: BB/H021027/1
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard

Training for the next generation of Bioprocessing leaders

2009-10-01 to 2013-09-30 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: BB/G016593/1
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard

Integrating upstream host cell line selection and development with improved downstream bioprocessing

Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard
grade
Preferred source (of 4)‎

IMRC for Bioprocessing

2007-03-31 to 2012-03-30 | Grant
Engineering and Physical Sciences Research Council (Swindon, GB)
GRANT_NUMBER: EP/E001599/1
GRANT_NUMBER: EP/E001599/1
Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard
grade
Preferred source (of 4)‎

A new microfluidic tool for rapid analysis of protein stability and integrity in bioprocesses

Source: Self-asserted source
Daniel G. Bracewell via DimensionsWizard
grade
Preferred source (of 4)‎

Peer review (11 reviews for 8 publications/grants)

Review activity for ACS applied materials & interfaces. (1)
Review activity for ACS synthetic biology. (1)
Review activity for Acta biomaterialia. (1)
Review activity for Analytical chemistry. (1)
Review activity for Biotechnology advances. (1)
Review activity for Journal of membrane science. (1)
Review activity for Molecular therapy. (1)
Review activity for Separation and purification technology. (4)