Personal information

NGS, Bioinformatics, Breast cancer, RNA-seq, R, Bash

Activities

Employment (3)

MultiplexDX: Bratislava, SK

2023-08 to present | Senior Scientist
Employment
Source: Self-asserted source
Natália Valková

MultiplexDX: Bratislava, SK

2022-06 to 2023-07 | Scientist
Employment
Source: Self-asserted source
Natália Valková

Czech Academy of Sciences, Institute of Biophysics: Brno, CZ

2019-01 to 2022-06 | Doctoral researcher
Employment
Source: Self-asserted source
Natália Valková

Education and qualifications (1)

Masaryk University: Brno, CZ

2019-09 to 2023-09 | PhD in Molecular and Cell Biology and Genetics (Department of Experimental Biology)
Education
Source: Self-asserted source
Natália Valková

Works (21)

The spatially informed mFISHseq assay resolves biomarker discordance and predicts treatment response in breast cancer

Nature Communications
2025-01-02 | Journal article
Contributors: Evan D. Paul; Barbora Huraiová; Natália Valková; Natalia Matyasovska; Daniela Gábrišová; Soňa Gubová; Helena Ignačáková; Tomáš Ondris; Michal Gala; Liliane Barroso et al.
Source: check_circle
Crossref

Multiplexed RNA-FISH-guided Laser Capture Microdissection RNA Sequencing Improves Breast Cancer Molecular Subtyping, Prognostic Classification, and Predicts Response to Antibody Drug Conjugates

2023-12-06 | Preprint
Contributors: Evan D. Paul; Barbora Huraiová; Natália Valková; Natalia Birknerova; Daniela Gábrišová; Sona Gubova; Helena Ignačáková; Tomáš Ondris; Silvia Bendíková; Jarmila Bíla et al.
Source: check_circle
Crossref

Transactivation by partial function P53 family mutants is increased by the presence of G-quadruplexes at a promoter site.

Biochimie
2023-10-13 | Journal article
Contributors: Vojsovič M; Kratochvilová L; Valková N; Šislerová L; El Rashed Z; Menichini P; Inga A; Monti P; Brázda V
Source: Self-asserted source
Natália Valková

G-quadruplexes in the evolution of hepatitis B virus.

Nucleic acids research
2023-08-01 | Journal article
Contributors: Václav Brázda; Dobrovolná M; Bohálová N; Mergny JL
Source: Self-asserted source
Natália Valková

Dual mode of IFI16 binding to supercoiled and linear DNA: A closer insight.

Biochemical and biophysical research communications
2023-05-15 | Journal article
Contributors: Valková N; Kratochvilová L; Martinková L; Václav Brázda
Source: Self-asserted source
Natália Valková

G-quadruplex ligands as potent regulators of lysosomes.

Autophagy
2023-02-05 | Journal article
Contributors: Ferret L; Alvarez-Valadez K; Rivière J; Muller A; Bohálová N; Yu L; Lionel Guittat; Václav Brázda; Guido Kroemer; Mergny JL et al.
Source: Self-asserted source
Natália Valková

Analysis of G-Quadruplex-Forming Sequences in Drought Stress-Responsive Genes, and Synthesis Genes of Phenolic Compounds in Arabidopsis thaliana

Life
2023-01-10 | Journal article
Contributors: Petr Pečinka; Natália Bohálová; Adriana Volná; Kristýna Kundrátová; Václav Brázda; Martin Bartas
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

The Newly Sequenced Genome of Pisum sativum Is Replete with Potential G-Quadruplex-Forming Sequences—Implications for Evolution and Biological Regulation

International Journal of Molecular Sciences
2022-07-30 | Journal article
Contributors: Michaela Dobrovolná; Natália Bohálová; Vratislav Peška; Jiawei Wang; Yu Luo; Martin Bartas; Adriana Volná; Jean-Louis Mergny; Václav Brázda
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Interaction of Proteins with Inverted Repeats and Cruciform Structures in Nucleic Acids.

International journal of molecular sciences
2022-05-31 | Journal article
Contributors: Richard Peter Bowater; Bohálová N; Václav Brázda
Source: Self-asserted source
Natália Valková

G-quadruplexes in helminth parasites.

Nucleic acids research
2022-03-01 | Journal article
Contributors: Cantara A; Yu Luo; Dobrovolná M; Bohalova N; Fojta M; Daniela Verga; Guittat L; Cucchiarini A; Savrimoutou S; Häberli C et al.
Source: Self-asserted source
Natália Valková

New telomere to telomere assembly of human chromosome 8 reveals a previous underestimation of G-quadruplex forming sequences and inverted repeats

Gene
2022-02 | Journal article
Contributors: Václav Brázda; Natália Bohálová; Richard P. Bowater
Source: check_circle
Crossref

Conservation and over-representation of G-quadruplex sequences in regulatory regions of mitochondrial DNA across distinct taxonomic sub-groups.

Biochimie
2021-12-20 | Journal article
Contributors: Bohálová N; Dobrovolná M; Brázda V; Stefan Bidula
Source: Self-asserted source
Natália Valková

Novel G-quadruplex prone sequences emerge in the complete assembly of the human X chromosome.

Biochimie
2021-09-09 | Journal article
Contributors: Bohálová N; Mergny JL; Václav Brázda
Source: Self-asserted source
Natália Valková

Analysis of putative quadruplex-forming sequences in fungal genomes: novel antifungal targets?

Microbial genomics
2021-05-01 | Journal article
Contributors: Warner EF; Bohálová N; Václav Brázda; Zoe Waller; Stefan Bidula
Source: Self-asserted source
Natália Valková

Analyses of viral genomes for G-quadruplex forming sequences reveal their correlation with the type of infection.

Biochimie
2021-04-09 | Journal article
Contributors: Bohálová N; Cantara A; Bartas M; Kaura P; Jiri Stastny; Pečinka P; Fojta M; Mergny JL; Václav Brázda
Source: Self-asserted source
Natália Valková

Tracing dsDNA Virus-Host Coevolution through Correlation of Their G-Quadruplex-Forming Sequences.

International journal of molecular sciences
2021-03-26 | Journal article | Author
Contributors: Natália Valková; Cantara A; Martin Bartas; Kaura P; Jiri Stastny; Petr Pečinka; Miroslav Fojta; Václav Brázda
Source: Self-asserted source
Natália Valková
grade
Preferred source (of 3)‎

Evaluating the Influence of a G-Quadruplex Prone Sequence on the Transactivation Potential by Wild-Type and/or Mutant P53 Family Proteins through a Yeast-Based Functional Assay

Genes
2021-02 | Journal article | Author
Contributors: Paola Monti; Václav Brázda; Natália Valková; Otília Porubiaková; Paola Menichini; Andrea Speciale; Renata Bocciardi; Alberto Inga; Gilberto Fronza
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

G-quadruplexes in H1N1 influenza genomes.

BMC genomics
2021-01-23 | Journal article
Source: Self-asserted source
Natália Valková
grade
Preferred source (of 2)‎

SARS-CoV-2 hot-spot mutations are significantly enriched within inverted repeats and CpG island loci.

Briefings in bioinformatics
2020-12-21 | Journal article
Source: Self-asserted source
Natália Valková

In-Depth Bioinformatic Analyses of <i>Nidovirales</i> Including Human SARS-CoV-2, SARS-CoV, MERS-CoV Viruses Suggest Important Roles of Non-canonical Nucleic Acid Structures in Their Lifecycles.

Frontiers in microbiology
2020-07-03 | Journal article
Source: Self-asserted source
Natália Valková

The Influence of Quadruplex Structure in Proximity to P53 Target Sequences on the Transactivation Potential of P53 Alpha Isoforms.

International journal of molecular sciences
2019-12-24 | Journal article
Source: Self-asserted source
Natália Valková