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Isoform-level expression of the constitutive androstane receptor (CAR or NR1I3) transcription factor better predicts the mRNA expression of the cytochrome P450s in human liver samples

Drug Metabolism and Disposition
2025-01 | Journal article
DOI: 10.1124/dmd.124.001923
Contributors: Joseph M. Collins; Danxin Wang
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DNA Methylation in the CYP3A Distal Regulatory Region (DRR) Is Associated with the Expression of CYP3A5 and CYP3A7 in Human Liver Samples

Molecules
2024-11-16 | Journal article
DOI: 10.3390/molecules29225407
Contributors: Joseph M. Collins; Danxin Wang
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A Comprehensive Evaluation of the Effects of RNA-Editing Proteins ADAR and ADARB1 on the Expression of the Drug-Metabolizing Enzymes in HepaRG Cells

Drug Metabolism and Disposition
2023-11 | Journal article
DOI: 10.1124/dmd.123.001396
Contributors: Joseph M. Collins; Danxin Wang
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Transcriptional regulation of carboxylesterase 1 (CES1) in human liver: role of the nuclear receptor NR1H3 (LXRα) and its splice isoforms

Drug Metabolism and Disposition
2021-10-25 | Journal article
DOI: 10.1124/dmd.121.000649
Contributors: Joseph M Collins; Rong Lu; Xinwen Wang; Hao-Jie Zhu; Danxin Wang
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