Personal information

Verified email addresses

United States

Biography

Presently, I am working as a Senior Research Scientist at Memorial Sloan Kettering Cancer Center, New York, USA. My research interest includes “epigenetics and transcriptional regulation”. My research work is focused on exploring the microenvironment of high-grade tumors that arise in the overall course of the disease and in relation to treatment.

During 2021-22, I worked as Postdoctoral Research Scientist at Columbia University, New York, US. My work was to explore differences between regulatory networks involved in cancer and normal tissues using bioinformatics and computational biology. Earlier, I was working as Post-Doc at TAGC, INSERM, Aix Marseille University, Marseille, France during 2018-21. My research work was focused on the Identification of Epromoters, promoters showing enhancer activity, like clusters in various stress conditions. We have developed a pipeline to identify Epromoter-like clusters. During 2016-18, I worked as Research Associate at CSIR-Institute of Genomics & Integrative Biology, New Delhi, India. My work was focused on the identification and validation of genetic and epigenetic biomarkers for high-altitude phenotypes using bioinformatics approaches. I pursued my Ph.D. work at the Department of Biochemistry, All India Institute of Medical Sciences (AIIMS), New Delhi, India, and earned my Ph.D. degree from NIU, India in 2016.

In my tenure, I have published around FIFTY Articles. In addition to this, I was awarded an Independent Research Project from the Indian Council of Medical Research, India. I was also an Invited Researcher (two times) at the Department of Medical Chemistry, Medical University of Vienna, Vienna, Austria. I was also awarded various travel grants from Indian and overseas funding agencies to present my research work.

Activities

Employment (5)

Sloan Kettering Institute: New York, NY, US

2022-03-15 to present | Senior Research Scientist (Solomon lab)
Employment
Source: check_circle
Memorial Sloan Kettering Cancer Center

Columbia University Irving Medical Center: New York, NY, US

2021-03-15 to present | Postdoctoral Research Scientist (Systems Biology)
Employment
Source: Self-asserted source
Himanshu Narayan Singh

Aix-Marseille Université: Marseille, Provence-Alpes-Côte d'Azu, FR

2016-07-01 to 2021-02-28 | Post Doctoral Fellow (INSERM U1090)
Employment
Source: Self-asserted source
Himanshu Narayan Singh

CSIR-Institute of Genomcis & Integrative Biology: Delhi, Delhi, IN

2018-08-01 to 2020-07-31 | Post Doctoral Fellow (Genomics & Molecular Biology)
Employment
Source: Self-asserted source
Himanshu Narayan Singh

All India Management Association: New Delhi, Delhi, IN

2011-09-01 to 2016-11-17 | Research Scholar (Biochemistry)
Employment
Source: Self-asserted source
Himanshu Narayan Singh

Education and qualifications (5)

Noida International University: Greater Noida, IN

2013-07-01 to 2016-12-28 | PhD (School of Sciences)
Education
Source: Self-asserted source
Himanshu Narayan Singh

Jamia Hamdard: New Delhi, IN

2009-07-01 to 2011-06-30 | M.Tech. (Bioinformatics) (Department of Computer, Science Faculty of Management & Information Technology)
Education
Source: Self-asserted source
Himanshu Narayan Singh

Institute of Advanced Studies in Education: Sardarshahar, Rajasthan, IN

2004-07-01 to 2008-06-30 | B.Tech. (Biotechnology) (Life Science)
Education
Source: Self-asserted source
Himanshu Narayan Singh

Udai Pratap College: Varanasi, Uttar Pradesh, IN

2003-07-01 to 2004-06-31 | 10+2
Education
Source: Self-asserted source
Himanshu Narayan Singh

Udai Pratap College: Varanasi, Uttar Pradesh, IN

2001-07-01 to 2002-06-31 | 10
Education
Source: Self-asserted source
Himanshu Narayan Singh

Professional activities (7)

Society for Neurochemistry India: Hyderabad, IN

Life Time
Membership
Source: Self-asserted source
Himanshu Narayan Singh

National Scientific and Technical Research Council: Buenos Aires, AR

Life Time
Membership
Source: Self-asserted source
Himanshu Narayan Singh

International Association of Engineers: Hong Kong, Hong Kong, CN

Life Time
Membership
Source: Self-asserted source
Himanshu Narayan Singh

Hypobaric Hypoxia Society: New Delhi, IN

General Secretary
Membership
Source: Self-asserted source
Himanshu Narayan Singh

DNA Society of India: Kolkata, IN

Life Time
Membership
Source: Self-asserted source
Himanshu Narayan Singh

Medical University of Vienna: Vienna, AT

2016-10-28 to 2016-11-13 | Invited Researcher (Department of Medical Chemistry)
Invited position
Source: Self-asserted source
Himanshu Narayan Singh

Medical University Vienna: Vienna, AT

2016-06-29 to 2016-07-22 | Invited Researcher (Dept. of Medical Chemistry)
Invited position
Source: Self-asserted source
Himanshu Narayan Singh

Funding (5)

International Travel Grant awarded from European Stroke Research Foundation (ESRF)

2016 to 2016 | Award
European Stroke Research Foundation (ESRF) (Venice, Italy, IT)
Source: Self-asserted source
Himanshu Narayan Singh

International Travel Grant awarded from ICHG2016, Kyoto, Japan

2016 to 2016 | Award
ICHG-2016, Kyoto, Japan (Kyoto, JP)
GRANT_NUMBER: 90439
Source: Self-asserted source
Himanshu Narayan Singh

International Travel Grant awarded by DBT

2015 to 2015 | Award
Department of Science and Technology (New Delhi, Delhi, IN)
GRANT_NUMBER: ITS/3691/2015-16
Source: Self-asserted source
Himanshu Narayan Singh

International Travel Grant from DBT, New Delhi, India

2015 to 2015 | Award
Department of Biotechnology (New Delhi, Delhi, IN)
Source: Self-asserted source
Himanshu Narayan Singh

Identification of Genes Containing DNA-Triplex Forming Large (Purine) Repeats in Human Genome and their application as therapeutic targets in Neurological disorders

2014-01 to 2016-12 | Salary award
Indian Council of Medical Research (New Delhi, New Delhi, IN)
Source: Self-asserted source
Himanshu Narayan Singh

Works (37)

Quercetin's antibiofilm effectiveness against drug resistant Staphylococcus aureus and its validation by in silico modeling

Research in Microbiology
2024-03 | Journal article
Contributors: Anjaneyulu Musini; Himanshu Narayan Singh; Jhansi Vulise; S.S. Sravanthi Pammi; Archana Giri
Source: check_circle
Crossref

Anticancer Drug Discovery Based on Natural Products: From Computational Approaches to Clinical Studies

Biomedicines
2024-01-16 | Journal article
Contributors: Pritee Chunarkar-Patil; Mohammed Kaleem; Richa Mishra; Subhasree Ray; Aftab Ahmad; Devvret Verma; Sagar Bhayye; Rajni Dubey; Himanshu Singh; Sanjay Kumar
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

SARS-CoV-2 Omicron Variant Genomic Sequences and Their Epidemiological Correlates Regarding the End of the Pandemic: In Silico Analysis

JMIR Bioinformatics and Biotechnology
2023-01-10 | Journal article
Contributors: Ashutosh Kumar; Adil Asghar; Himanshu N Singh; Muneeb A Faiq; Sujeet Kumar; Ravi K Narayan; Gopichand Kumar; Prakhar Dwivedi; Chetan Sahni; Rakesh K Jha et al.
Source: check_circle
Crossref

Transcriptomic Profiling Unravels Novel Deregulated Gene Signatures Associated with Acute Myocardial Infarction: A Bioinformatics Approach

Genes
2022-12-09 | Journal article
Contributors: Sanjay Kumar; Chun-Ming Shih; Lung-Wen Tsai; Rajni Dubey; Deepika Gupta; Tanmoy Chakraborty; Naveen Sharma; Abhishek Singh; Vishnu Swarup; Himanshu Singh
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Genome-wide expression reveals potential biomarkers in breast cancer bone metastasis

Journal of Integrative Bioinformatics
2022-09-30 | Journal article
Contributors: Yashbir Singh; Naidu Subbarao; Abhinav Jaimini; Quincy A. Hathaway; Amina Kunovac; Bradley Erickson; Vishnu Swarup; Himanshu Narayan Singh
Source: check_circle
Crossref

Emerging SARS‐CoV‐2 variants can potentially break set epidemiological barriers in COVID‐19

Journal of Medical Virology
2022-04 | Journal article
Contributors: Ashutosh Kumar; Rakesh Parashar; Sujeet Kumar; Muneeb A Faiq; Chiman Kumari; Maheswari Kulandhasamy; Ravi K. Narayan; Rakesh K. Jha; Himanshu N. Singh; Pranav Prasoon et al.
Source: check_circle
Crossref

Targeting rock2 isoform with its widely used inhibitors for faster post-stroke recovery

Indian Journal of Biochemistry and Biophysics
2021 | Journal article
EID:

2-s2.0-85100629766

Part of ISSN: 09750959 03011208
Contributors: Appunni, S.; Gupta, D.; Rubens, M.; Singh, A.K.; Swarup, V.; Singh, H.N.
Source: Self-asserted source
Himanshu Narayan Singh via Scopus - Elsevier

An in silico analysis of early SARS-CoV-2 variant B.1.1.529 (Omicron) genomic sequences and their epidemiological correlates

2021-12-22 | Preprint
Contributors: Ashutosh Kumar; Adil Asghar; Himanshu N. Singh; Muneeb A. Faiq; Sujeet Kumar; Ravi K. Narayan; Gopichand Kumar; Prakhar Dwivedi; Chetan Sahni; Rakesh K. Jha et al.
Source: check_circle
Crossref

Epromoters function as a hub to recruit key transcription factors required for the inflammatory response

Nature Communications
2021-11-18 | Journal article
Contributors: David Santiago-Algarra; Charbel Souaid; Himanshu Singh; Lan T. M. Dao; Saadat Hussain; Alejandra Medina-Rivera; Lucia Ramirez-Navarro; Jaime A. Castro-Mondragon; Nori Sadouni; Guillaume Charbonnier et al.
Source: check_circle
Crossref

A novel computational methodology for GWAS multi-locus analysis based on graph theory and machine learning

2021-10-26 | Preprint
Contributors: Subrata Saha; Himanshu Narayan Singh; Ahmed Soliman; Sanguthevar Rajasekaran
Source: check_circle
Crossref

CRISPR/Cas9 technology in neurological disorders: An update for clinicians

Annals of Movement Disorders
2020 | Journal article
EID:

2-s2.0-85108263568

Part of ISSN: 25903454 25903446
Contributors: Swarup, V.; Kumar, V.; Faruq, M.; Singh, H.; Singh, I.; Srivastava, A.K.
Source: Self-asserted source
Himanshu Narayan Singh via Scopus - Elsevier

Relevance of SARS-CoV-2 related factors ACE2 and TMPRSS2 expressions in gastrointestinal tissue with pathogenesis of digestive symptoms, diabetes-associated mortality, and disease recurrence in COVID-19 patients

bioRxiv
2020 | Other
EID:

2-s2.0-85098907406

Part of ISSN: 26928205
Contributors: Kumar, A.; Faiq, M.A.; Pareek, V.; Raza, K.; Narayan, R.K.; Prasoon, P.; Kumar, P.; Kulandhasamy, M.; Kumari, C.; Kant, K. et al.
Source: Self-asserted source
Himanshu Narayan Singh via Scopus - Elsevier

Relevance of SARS-CoV-2 related factors ACE2 and TMPRSS2 expressions in gastrointestinal tissue with pathogenesis of digestive symptoms, diabetes-associated mortality, and disease recurrence in COVID-19 patients

Medical Hypotheses
2020 | Journal article
EID:

2-s2.0-85090992362

Part of ISSN: 15322777 03069877
Contributors: Kumar, A.; Faiq, M.A.; Pareek, V.; Raza, K.; Narayan, R.K.; Prasoon, P.; Kumar, P.; Kulandhasamy, M.; Kumari, C.; Kant, K. et al.
Source: Self-asserted source
Himanshu Narayan Singh via Scopus - Elsevier

Transcriptomic analysis of the signature of neurogenesis in human hippocampus suggests restricted progenitor cell progression post-childhood

IBRO Reports
2020 | Journal article
EID:

2-s2.0-85090985251

Part of ISSN: 24518301
Contributors: Kumar, A.; Pareek, V.; Faiq, M.A.; Kumar, P.; Kumari, C.; Singh, H.N.; Ghosh, S.K.
Source: Self-asserted source
Himanshu Narayan Singh via Scopus - Elsevier

Encephalitis (Brain Fever): A medical mystry due to brain viral infection leading cause of premature deaths in India

EC Paediatrics
2019 | Other
Source: Self-asserted source
Himanshu Narayan Singh

Transcriptomic analysis of the neurogenesis signature suggests continued but minimal neurogenesis in the Adult Human Hippocampus

bioRxiv
2019 | Other
EID:

2-s2.0-85095645446

Part of ISSN: 26928205
Contributors: Kumar, A.; Pareek, V.; Faiq, M.A.; Kumar, P.; Kumari, C.; Singh, H.N.; Ghosh, S.K.
Source: Self-asserted source
Himanshu Narayan Singh via Scopus - Elsevier

Altered Expression of a Unique Set of Genes Reveals Complex Etiology of Schizophrenia.

Frontiers in Psychiatry
2019-12-12 | Journal article
Source: Self-asserted source
Himanshu Narayan Singh
grade
Preferred source (of 2)‎

A Novel Mathematical Model of Glaucoma Pathogenesis.

Journal of current glaucoma practice
2019-01-01 | Journal article
Source: Self-asserted source
Himanshu Narayan Singh
grade
Preferred source (of 2)‎

Recent Advances in Stroke Genetics

Advances in Stroke Research
2018 | Book chapter
Source: Self-asserted source
Himanshu Narayan Singh

Commentary: A Possible Mechanism of Zika Virus Associated Microcephaly: Imperative Role of Retinoic Acid Response Element (RARE) Consensus Sequence Repeats in the Viral Genome.

Frontiers in microbiology
2018-02-20 | Journal article
Source: Self-asserted source
Himanshu Narayan Singh
grade
Preferred source (of 2)‎

Altered expression of a unique set of genes reveals complex etiology of Schizophrenia

bioRxiv
2017 | Other
EID:

2-s2.0-85095633351

Part of ISSN: 26928205
Contributors: Kumar, A.; Singh, H.N.; Pareek, V.; Raza, K.; Kumar, P.; Faiq, M.A.; Mochan, S.; Dantham, S.; Upadhyaya, A.D.
Source: Self-asserted source
Himanshu Narayan Singh via Scopus - Elsevier

Recent Advances in Stroke Genetics

Advances in Stroke Research
2017 | Book chapter
Source: Self-asserted source
Himanshu Narayan Singh

nTrackAnnotator : Software for detection and annotation of sequence tracks of chosen nucleic acid bases with defined length in genome

Gene Reports
2017-06 | Journal article
Part of ISSN: 2452-0144
Source: Self-asserted source
Himanshu Narayan Singh
grade
Preferred source (of 2)‎

DNA trinucleotide (GAA) repeats in human genome: hint for disease pathogenesis?

Journal of biomolecular structure & dynamics
2017-06-23 | Journal article
Source: Self-asserted source
Himanshu Narayan Singh
grade
Preferred source (of 2)‎

DNA-triplex Forming Purine Repeat Containing Genes in Acinetobacter baumannii and Their Association with Infection and Adaptation.

Frontiers in Cellular and Infection Microbiology
2017-06-16 | Journal article
Source: Self-asserted source
Himanshu Narayan Singh
grade
Preferred source (of 2)‎

No changes in heme synthesis in human Friedreich´s ataxia erythroid progenitor cells.

Gene
2017-04-12 | Journal article
Source: Self-asserted source
Himanshu Narayan Singh
grade
Preferred source (of 2)‎

Assessment of binding properties of Actinomycin-D to 21nt DNA segment of hmgb1 gene promoter using spectroscopic and calorimetric techniques.

Journal of biomolecular structure & dynamics
2017-02-08 | Journal article
Source: Self-asserted source
Himanshu Narayan Singh
grade
Preferred source (of 2)‎

Targeting PknB, an eukaryotic-like serine/threonine protein kinase of Mycobacterium tuberculosis with phytomolecules.

Computational biology and chemistry
2017-01-09 | Journal article
Source: Self-asserted source
Himanshu Narayan Singh
grade
Preferred source (of 2)‎

Searching new targets to counter drug resistance - GTPase-Obg mRNA expression analysis in Mycobacterium under stress and in silico docking with GTPase inhibitors.

Journal of biomolecular structure & dynamics
2016-08-12 | Journal article
Source: Self-asserted source
Himanshu Narayan Singh
grade
Preferred source (of 2)‎

A Possible Mechanism of Zika Virus Associated Microcephaly: Imperative Role of Retinoic Acid Response Element (RARE) Consensus Sequence Repeats in the Viral Genome.

Frontiers in human neuroscience
2016-08-09 | Journal article
Source: Self-asserted source
Himanshu Narayan Singh
grade
Preferred source (of 2)‎

Structural aspects of the interaction of anticancer drug Actinomycin-D to the GC rich region of hmgb1 gene.

International journal of biological macromolecules
2016-02-26 | Journal article
Source: Self-asserted source
Himanshu Narayan Singh
grade
Preferred source (of 2)‎

Gene regulation by long purine tracks in brain related diseases.

Data in Brief
2015-09-04 | Journal article
Source: Self-asserted source
Himanshu Narayan Singh
grade
Preferred source (of 2)‎

Role of long purine stretches in controlling the expression of genes associated with neurological disorders.

Gene
2015-07-03 | Journal article
Source: Self-asserted source
Himanshu Narayan Singh
grade
Preferred source (of 2)‎

Identification of genes containing expanded purine repeats in the human genome and their apparent protective role against cancer.

Journal of biomolecular structure & dynamics
2015-06-25 | Journal article
Source: Self-asserted source
Himanshu Narayan Singh
grade
Preferred source (of 2)‎

Interaction of adriamycin with a regulatory element of hmgb1: spectroscopic and calorimetric approach.

Journal of biomolecular structure & dynamics
2014-10-14 | Journal article
Source: Self-asserted source
Himanshu Narayan Singh
grade
Preferred source (of 2)‎

In-Silico Identification of LTR type Retrotransposons and Their Transcriptional Activities in Solanum Tuberosum

International Journal of Soft Computing and Engineering
2013 | Journal article
Source: Self-asserted source
Himanshu Narayan Singh

COVID-19: A Review on Molecular Basis, Pathogenic Mechanisms, Therapeutic Aspects and Future Projections<strong> </strong>

Source: check_circle
Multidisciplinary Digital Publishing Institute

Peer review (6 reviews for 5 publications/grants)

Review activity for Brain sciences. (1)
Review activity for Genes. (1)
Review activity for Mayo Clinic proceedings. (2)
Review activity for Pharmaceutics. (1)
Review activity for World journal of surgical oncology (1)