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Employment (1)

Duke University: Durham, NC, US

2018-08 to present | PhD Graduate Student (Chemistry )
Employment
Source: Self-asserted source
C. Skyler Cochrane

Education and qualifications (2)

Duke University: Durham, North Carolina, US

2018-08-15 to 2023-07-10 | PhD Candidate (Chemistry)
Education
Source: Self-asserted source
C. Skyler Cochrane

Rhodes College: Memphis, TN, US

2014-08 to 2018-05 | Bachelor of Science (Chemistry)
Education
Source: Self-asserted source
C. Skyler Cochrane

Works (7)

Preclinical safety and efficacy characterization of an LpxC inhibitor against Gram-negative pathogens

Science Translational Medicine
2023-08-09 | Journal article
DOI: 10.1126/scitranslmed.adf5668
Contributors: Jinshi Zhao; C. Skyler Cochrane; Javaria Najeeb; David Gooden; Carly Sciandra; Ping Fan; Nadine Lemaitre; Kate Newns; Robert A. Nicholas; Ziqiang Guan et al.
Source: check_circle
Crossref

Synthesis and analysis of novel catecholic ligands as inhibitors of catechol-O-methyltransferase

Bioorganic & Medicinal Chemistry Letters
2023-04 | Journal article
DOI: 10.1016/j.bmcl.2023.129286
Part of ISSN: 0960-894X
Contributors: A. Katherine Hatstat; Grace M. Kennedy; Trevor R. Squires; Gisela Xhafkollari; C. Skyler Cochrane; Mauricio Cafiero; Larryn Peterson
Source: Self-asserted source
C. Skyler Cochrane

Development of LpxH Inhibitors Chelating the Active Site Dimanganese Metal Cluster of LpxH

ChemMedChem
2023-04-17 | Journal article
DOI: 10.1002/cmdc.202300023
Part of ISSN: 1860-7179
Part of ISSN: 1860-7187
Contributors: Seung-Hwa Kwak; C. Skyler Cochrane; Jae Cho; Patrick A. Dome; Amanda Ennis; Jea Hyun Kim; Pei Zhou; Jiyong Hong
Source: Self-asserted source
C. Skyler Cochrane

L-DOPA Dioxygenase Activity on 6-Substituted Dopamine Analogues

Biochemistry
2021-08-17 | Journal article
DOI: 10.1021/acs.biochem.1c00310
Part of ISSN: 0006-2960
Part of ISSN: 1520-4995
Contributors: Alexander M. Goldberg; Miranda K. Robinson; Erykah S. Starr; Ryan N. Marasco; Alexa C. Alana; C. Skyler Cochrane; Kameron L. Klugh; David J. Strzeminski; Muxue Du; Keri Colabroy et al.
Source: Self-asserted source
C. Skyler Cochrane

Synthesis and evaluation of sulfonyl piperazine LpxH inhibitors

Bioorganic Chemistry
2020-09 | Journal article
DOI: 10.1016/j.bioorg.2020.104055
Part of ISSN: 0045-2068
Contributors: Seung-Hwa Kwak; C. Skyler Cochrane; Amanda F. Ennis; Won Young Lim; Caroline G. Webster; Jae Cho; Benjamin A. Fenton; Pei Zhou; Jiyong Hong
Source: Self-asserted source
C. Skyler Cochrane

Structural basis of the UDP-diacylglucosamine pyrophosphohydrolase LpxH inhibition by sulfonyl piperazine antibiotics

Proceedings of the National Academy of Sciences
2020-02-25 | Journal article
DOI: 10.1073/pnas.1912876117
Part of ISSN: 0027-8424
Part of ISSN: 1091-6490
Contributors: Jae Cho; Minhee Lee; C. Skyler Cochrane; Caroline G. Webster; Benjamin A. Fenton; Jinshi Zhao; Jiyong Hong; Pei Zhou
Source: Self-asserted source
C. Skyler Cochrane

Catechol reactivity: Synthesis of dopamine derivatives substituted at the 6-position

Synthetic Communications
2017-03-04 | Journal article
DOI: 10.1080/00397911.2016.1269350
Part of ISSN: 0039-7911
Part of ISSN: 1532-2432
Contributors: Jennifer C. Rote; Sarah N. Malkowski; C. Skyler Cochrane; Gabrielle E. Bailey; Noah S. Brown; Mauricio Cafiero; Larryn W. Peterson
Source: Self-asserted source
C. Skyler Cochrane
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