Personal information

Biography

An accomplished Board Certified Toxicologist with over 25 years of experience and achievements in oil and gas industry (6+ years), biotechnology start-up company and academia. Founding Toxicologist in PETRONAS with proven strategic and leadership in integrating toxicology and product stewardship to ensure sustainable value creation throughout the product life cycle. Strategically grown the section to a current team comprising of experts in (Eco)Toxicology, Product Stewardship and Environmental Health. Significant leadership and managerial experience in university and start-up biotechnology company. Over 40 publications and extensive research experience funded by national and international grants.

Activities

Employment (1)

Petroliam Nasional Bhd: Kuala Lumpur, WP, MY

2013-02-16 to present | Head (Product Stewardship & Toxicology)
Employment
Source: Self-asserted source
Salmaan H Inayat-Hussain

Education and qualifications (2)

University of Leicester Medical School: Leicester, Leicester, GB

1993-05-18 to 1997-05-17 | PhD (MRC Toxicology Unit)
Education
Source: Self-asserted source
Salmaan H Inayat-Hussain

Universiti Kebangsaan Malaysia: Kuala Lumpur, MY

1987-07-01 to 1991-04-01 | BSc (Hons) (Pharmacology)
Education
Source: Self-asserted source
Salmaan H Inayat-Hussain

Professional activities (1)

Yale University School of Public Health: New Haven, CT, US

2018-11-08 to present | Adjunct Professor (Environmental Health Sciences)
Invited position
Source: Self-asserted source
Salmaan H Inayat-Hussain

Works (50 of 51)

Items per page:
Page 1 of 2

Determining the endocrine disruption potential of industrial chemicals using an integrative approach: Public databases, in vitro exposure, and modeling receptor interactions

Environment International
2019 | Journal article
EID:

2-s2.0-85068826542

Contributors: Alofe, O.; Kisanga, E.; Inayat-Hussain, S.H.; Fukumura, M.; Garcia-Milian, R.; Perera, L.; Vasiliou, V.; Whirledge, S.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Evaluation of potential carcinogenicity of organic chemicals in synthetic turf crumb rubber

Environmental Research
2019 | Journal article
EID:

2-s2.0-85056644592

Contributors: Perkins, A.N.; Inayat-Hussain, S.H.; Deziel, N.C.; Johnson, C.H.; Ferguson, S.S.; Garcia-Milian, R.; Thompson, D.C.; Vasiliou, V.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Hazard assessment for hazardous air pollutants from petroleum refinery operations using multi-country regulatory databases

Society of Petroleum Engineers - SPE Symposium: Asia Pacific Health, Safety, Security, Environment and Social Responsibility 2019
2019 | Conference paper
EID:

2-s2.0-85066759570

Contributors: Ismail, M.; Hussain, S.H.I.; Yoneda, M.; Latif, M.T.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Workplace management of carcinogens, mutagens and reproductive toxicants

Society of Petroleum Engineers - SPE Symposium: Asia Pacific Health, Safety, Security, Environment and Social Responsibility 2019
2019 | Conference paper
EID:

2-s2.0-85066749689

Contributors: Abu-Bakar, A.; Fukumura, M.; Inayat Hussain, S.H.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Prioritization of reproductive toxicants in unconventional oil and gas operations using a multi-country regulatory data-driven hazard assessment

Environment International
2018 | Journal article
EID:

2-s2.0-85047263307

Contributors: Inayat-Hussain, S.H.; Fukumura, M.; Muiz Aziz, A.; Jin, C.M.; Jin, L.W.; Garcia-Milian, R.; Vasiliou, V.; Deziel, N.C.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Cohort Profile: The Malaysian Cohort (TMC) project: A prospective study of non-communicable diseases in a multi-ethnic population

International Journal of Epidemiology
2015 | Journal article
EID:

2-s2.0-84936769188

Contributors: Jamal, R.; Syed Zakaria, S.Z.; Kamaruddin, M.A.; Abd Jalal, N.; Ismail, N.; Mohd Kamil, N.; Abdullah, N.; Baharudin, N.; Hussin, N.H.; Othman, H. et al.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Lineage-related cytotoxicity and clonogenic profile of 1,4-benzoquinone-exposed hematopoietic stem and progenitor cells

Toxicology and Applied Pharmacology
2015 | Journal article
EID:

2-s2.0-84923025631

Contributors: Chow, P.W.; Abdul Hamid, Z.; Chan, K.M.; Inayat-Hussain, S.H.; Rajab, N.F.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Toxicity of tetramethylammonium hydroxide to aquatic organisms and its synergistic action with potassium iodide

Chemosphere
2015 | Journal article
EID:

2-s2.0-84912116065

Contributors: Mori, I.C.; Arias-Barreiro, C.R.; Koutsaftis, A.; Ogo, A.; Kawano, T.; Yoshizuka, K.; Inayat-Hussain, S.H.; Aoyama, I.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Involvement of Seladin-1 in goniothalamin-induced apoptosis in urinary bladder cancer cells

BMC Complementary and Alternative Medicine
2014 | Journal article
EID:

2-s2.0-84906841464

Contributors: Yen, H.K.; Fauzi, A.-R.; Din, L.B.; McKelvey-Martin, V.J.; Meng, C.K.; Inayat-Hussain, S.H.; Rajab, N.F.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

N,N-Dimethylacetamide

Encyclopedia of Toxicology: Third Edition
2014 | Book chapter
EID:

2-s2.0-85038009404

Contributors: Ghazali, A.R.; Inayat-Hussain, S.H.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Erratum: Design, synthesis, in vitro cytotoxicity evaluation and structure-activity relationship of Goniothalamin analogs (Archives of Pharmacal Research DOI 10.1007/s12272-013-0099-1)

Archives of Pharmacal Research
2013 | Journal article
EID:

2-s2.0-84880038570

Contributors: Mohideen, M.; Zulkepli, S.; Nik-Salleh, N.-S.; Leong, L.H.; Chan, K.M.; Inayat-Hussain, S.H.; Zulkefeli, M.; Weber, J.-F.F.; Rahman, A.F.M.M.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Styryl-lactone goniothalamin inhibits TNF-α-induced NF-κB activation

Food and Chemical Toxicology
2013 | Journal article
EID:

2-s2.0-84881002603

Contributors: Orlikova, B.; Schumacher, M.; Juncker, T.; Yan, C.C.; Inayat-Hussain, S.H.; Hajjouli, S.; Cerella, C.; Dicato, M.; Diederich, M.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

3,5-Dibenzyloxy-4'-hydroxystilbene induces early caspase-9 activation during apoptosis in human K562 chronic myelogenous leukemia cells

Journal of Toxicological Sciences
2012 | Journal article
EID:

2-s2.0-84856881324

Contributors: Roslie, H.; Chan, K.M.; Rajab, N.F.; Velu, S.S.; Kadir, S.A.I.A.S.A.; Bunyamin, I.; Weber, J.-F.F.; Thomas, N.F.; Majeed, A.B.A.; Myatt, G. et al.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Protection of hydroquinone-induced apoptosis by downregulation of Fau is mediated by NQO1

Free Radical Biology and Medicine
2012 | Journal article
EID:

2-s2.0-84867332822

Contributors: Siew, E.L.; Chan, K.M.; Williams, G.T.; Ross, D.; Inayat-Hussain, S.H.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

The pyranoxanthone inophyllin A induces oxidative stress mediated-apoptosis in Jurkat T lymphoblastic leukemia cells

Food and Chemical Toxicology
2012 | Journal article
EID:

2-s2.0-84862753030

Contributors: Chan, K.M.; Hamzah, R.; Rahaman, A.A.; Jong, V.Y.M.; Khong, H.Y.; Rajab, N.F.; Ee, G.C.L.; Inayat-Hussain, S.H.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Cytotoxic and antioxidant effects of methoxylated stilbene analogues on HepG2 hepatoma and Chang liver cells: Implications for structure activity relationship

Human and Experimental Toxicology
2011 | Journal article
EID:

2-s2.0-78651068987

Contributors: Hasiah, A.H.; Ghazali, A.R.; Weber, J.F.F.; Velu, S.; Thomas, N.F.; Inayat Hussain, S.H.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Novel Biomarkers of Organophosphate Exposure

Anticholinesterase Pesticides: Metabolism, Neurotoxicity, and Epidemiology
2011 | Book chapter
EID:

2-s2.0-84885748893

Contributors: Satoh, T.; Inayat-Hussain, S.H.; Kamijima, M.; Ueyama, J.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

A bacterial biosensor for oxidative stress using the constitutively expressed redox-sensitive protein roGFP2

Sensors
2010 | Journal article
EID:

2-s2.0-77957103528

Contributors: Arias-Barreiro, C.R.; Okazaki, K.; Koutsaftis, A.; Inayat-Hussain, S.H.; Tani, A.; Katsuhara, M.; Kimbara, K.; Mori, I.C.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Challenges associated with the synthesis of unusual o-carboxamido stilbenes by the Heck protocol: Intriguing substituent effects, their toxicological and chemopreventive implications

Organic and Biomolecular Chemistry
2010 | Journal article
EID:

2-s2.0-78649499220

Contributors: Kee, C.H.; Ariffin, A.; Awang, K.; Takeya, K.; Morita, H.; Hussain, S.I.; Chan, K.M.; Wood, P.J.; Threadgill, M.D.; Lim, C.G. et al.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Goniothalamin induces coronary artery smooth muscle cells apoptosis: The p53-dependent caspase-2 activation pathway

Toxicological Sciences
2010 | Journal article
EID:

2-s2.0-77955098397

Contributors: Chan, K.M.; Rajab, N.F.; Siegel, D.; Din, L.B.; Ross, D.; Inayat-Hussain, S.H.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Goniothalamin-induced oxidative stress, DNA damage and apoptosis via caspase-2 independent and Bcl-2 independent pathways in Jurkat T-cells

Toxicology Letters
2010 | Journal article
EID:

2-s2.0-75949091374

Contributors: Inayat-Hussain, S.H.; Chan, K.M.; Rajab, N.F.; Din, L.B.; Chow, S.C.; Kizilors, A.; Farzaneh, F.; Williams, G.T.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Modulation of the benzene metabolite hydroquinone induced toxicity: Evidence for an important role of fau

Chemico-Biological Interactions
2010 | Journal article
EID:

2-s2.0-77950630007

Contributors: Inayat-Hussain, S.H.; Ibrahim, H.A.; Siew, E.L.; Rajab, N.F.; Chan, K.M.; Williams, G.T.; Ross, D.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Malaysia

Information Resources in Toxicology
2009 | Book chapter
EID:

2-s2.0-84882837535

Contributors: Inayat-Hussain, S.H.; Abu Bakar, J.; Ibrahim, E.; Mokhtar, M.; Alia Nunis, M.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Mutagenic and clastogenic characterization of poststerilized poly(3-hydroxybutyrate-co-4-hydroxybutyrate) copolymer biosynthesized by Delftia acidovorans

Journal of Biomedical Materials Research - Part A
2009 | Journal article
EID:

2-s2.0-70350342878

Contributors: Ee, L.S.; Rajab, N.F.; Osman, A.B.; Sudesh, K.; Inayat-Hussain, S.H.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

RACK-1 overexpression protects against goniothalamin-induced cell death

Toxicology Letters
2009 | Journal article
EID:

2-s2.0-70449533777

Contributors: Inayat-Hussain, S.H.; Wong, L.T.; Chan, K.M.; Rajab, N.F.; Din, L.B.; Harun, R.; Kizilors, A.; Saxena, N.; Mourtada-Maarabouni, M.; Farzaneh, F. et al.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

In vitro testing of biomaterials toxicity and biocompatibility

Cellular Response to Biomaterials
2008 | Book chapter
EID:

2-s2.0-84902404113

Contributors: Inayat-Hussain, S.; Rajab, N.F.; Siew, E.L.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

A comparative study of proteasomal inhibition and apoptosis induced in N27 mesencephalic cells by dopamine and MG132

Journal of Neurochemistry
2007 | Journal article
EID:

2-s2.0-34447324627

Contributors: Zafar, K.S.; Inayat-Hussain, S.H.; Ross, D.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

In vitro biocompatibility evaluation of poly(3-hydroxybutyrate-co-4- hydroxybutyrate) copolymer in fibroblast cells

Journal of Biomedical Materials Research - Part A
2007 | Journal article
EID:

2-s2.0-34247607283

Contributors: Ee, L.S.; Rajab, N.F.; Osman, A.B.; Sudesh, K.; Inayat-Hussain, S.H.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Is plasma β-glucuronidase a novel human biomarker for monitoring anticholinesterase pesticides exposure? A Malaysian experience

Toxicology and Applied Pharmacology
2007 | Journal article
EID:

2-s2.0-33847266715

Contributors: Inayat-Hussain, S.H.; Lubis, S.H.; Sakian, N.I.M.; Ghazali, A.R.; Ali, N.S.; el Sersi, M.; Toong, L.M.; Zainal, A.M.; Hashim, S.; Ghazali, M.S. et al.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Goniothalamin induces apoptosis in vascular smooth muscle cells

Chemico-Biological Interactions
2006 | Journal article
EID:

2-s2.0-29944433590

Contributors: Chan, K.M.; Rajab, N.F.; Ishak, M.H.A.; Ali, A.M.; Yusoff, K.; Din, L.B.; Inayat-Hussain, S.H.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Overexpression of NQO1 protects human SK-N-MC neuroblastoma cells against dopamine-induced cell death

Toxicology Letters
2006 | Journal article
EID:

2-s2.0-33748772788

Contributors: Zafar, K.S.; Inayat-Hussain, S.H.; Siegel, D.; Bao, A.; Shieh, B.; Ross, D.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Intrinsic pathway of hydroquinone induced apoptosis occurs via both caspase-dependent and caspase-independent mechanisms

Chemical Research in Toxicology
2005 | Journal article
EID:

2-s2.0-15344344380

Contributors: Inayat-Hussain, S.H.; Ross, D.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

RH1 induces cellular damage in an NAD(P)H:quinone oxidoreductase 1-dependent manner: Relationship between DNA cross-linking, cell cycle perturbations, and apoptosis

Journal of Pharmacology and Experimental Therapeutics
2005 | Journal article
EID:

2-s2.0-18044364834

Contributors: Dehn, D.L.; Inayat-Hussain, S.H.; Ross, D.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Cell death induced by hydroxyapatite on L929 fibroblast cells.

The Medical journal of Malaysia
2004 | Journal article
EID:

2-s2.0-16544383349

Contributors: Inayat-Hussain, S.H.; Rajab, N.F.; Roslie, H.; Hussin, A.A.; Ali, A.M.; Annuar, B.O.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

DNA damage evaluation of hydroxyapatite on fibroblast cell L929 using the single cell gel electrophoresis assay.

The Medical journal of Malaysia
2004 | Journal article
EID:

2-s2.0-16544362318

Contributors: Rajab, N.F.; Yaakob, T.A.; Ong, B.Y.; Hamid, M.; Ali, A.M.; Annuar, B.O.; Inayat-Hussain, S.H.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Recent advances in the discovery and development of stilbenes and lactones in anticancer therapy

Expert Opinion on Therapeutic Patents
2004 | Journal article
EID:

2-s2.0-3042844301

Contributors: Inayat-Hussain, S.H.; Thomas, N.F.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Loss of mitochondrial transmembrane potential and caspase-9 activation during apoptosis induced by the novel styryl-lactone goniothalamin in HL-60 leukemia cells

Toxicology in Vitro
2003 | Journal article
EID:

2-s2.0-0038771105

Contributors: Inayat-Hussain, S.H.; Annuar, B.O.; Din, L.B.; Ali, A.M.; Ross, D.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Altholactone, a novel styryl-lactone induces apoptosis via oxidative stress in human HL-60 leukemia cells

Toxicology Letters
2002 | Journal article
EID:

2-s2.0-0037188449

Contributors: Inayat-Hussain, S.H.; Osman, A.B.; Din, L.B.; Taniguchi, N.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Apoptosis induction in CEM-SS T-lymphoblastic leukemic cell line by goniothalamin

Journal of Biochemistry, Molecular Biology and Biophysics
2001 | Journal article
EID:

2-s2.0-0035761712

Contributors: Ali, A.M.; Umar-Tsafe, N.; Mohamed, S.M.; Inayat-Hussain, S.H.; Oo, K.T.; Yusoff, K.; Osman, A.B.; Din, L.B.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Differential involvement of caspases in hydroquinone-induced apoptosis in human leukemic HL-60 and Jurkat cells

Toxicology and Applied Pharmacology
2001 | Journal article
EID:

2-s2.0-0035448665

Contributors: Inayat-Hussain, S.H.; Winski, S.L.; Ross, D.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Caspase-dependent and -independent mechanisms in apoptosis induced by hydroquinone and catechol metabolites of remoxipride in HL-60 cells

Chemico-Biological Interactions
2000 | Journal article
EID:

2-s2.0-0034662755

Contributors: Inayat-Hussain, S.H.; McGuinness, S.M.; Johansson, R.; Lundstrom, J.; Ross, D.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

A reappraisal of the role of Zn<sup>2+</sup> in TGF-β<inf>1</inf>-induced apoptosis in primary hepatocytes

Cell Biology and Toxicology
1999 | Journal article
EID:

2-s2.0-0033237429

Contributors: Inayat-Hussain, S.H.; Cohen, G.M.; Cain, K.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Caspases-3 and -7 are activated in goniothalamin-induced apoptosis in human Jurkat T-cells

FEBS Letters
1999 | Journal article
EID:

2-s2.0-0032865433

Contributors: Inayat-Hussain, S.H.; Osman, A.B.; Din, L.B.; Ali, A.M.; Snowden, R.T.; MacFarlane, M.; Cain, K.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Processing/activation of CPP32-like proteases is involved in transforming growth factor β<inf>1</inf>-induced apoptosis in rat hepatocytes

Hepatology
1997 | Journal article
EID:

2-s2.0-0030961678

Contributors: Inayat-Hussain, S.H.; Couet, C.; Cohen, G.M.; Cain, K.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

A cleavage-site-directed inhibitor of interleukin-1β-converting enzyme-like proteases inhibits apoptosis in primary cultures of rat hepatocytes

Biochemical Journal
1996 | Journal article
EID:

2-s2.0-0029670683

Contributors: Cain, K.; Inayat-Hussain, S.H.; Couet, C.; Cohen, G.M.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

A novel method for detecting apoptosis shows that hepatocytes undergo a time dependent increase in DNA cleavage and chromatin condensation which is augmented after TGF-β<inf>1</inf> treatment

Cytometry
1996 | Journal article
EID:

2-s2.0-0029871999

Contributors: Cain, K.; Inayat-Hussain, S.H.; Couet, C.; Qin, H.-M.; Oberhammer, F.A.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Hepatocyte death following transforming growth factor-β1 addition

Microscopy Research and Technique
1996 | Journal article
EID:

2-s2.0-0029893782

Contributors: Oberhammer, F.; Froschl, G.; Tiefenbacher, R.; Inayat-Hussain, S.H.; Cain, K.; Stopper, H.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Staurosporine induces apoptosis in primary hepatocytes by the activation of interleukinlβ converting enzyme (ICE)-like proteases

Biochemical Society Transactions
1996 | Journal article
EID:

2-s2.0-3543034296

Contributors: Couel, C.; Inayat-Hussain, S.H.; Cain, K.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

Multi-step DNA cleavage in rat liver nuclei is inhibited by thiol reactive agents

FEBS Letters
1995 | Journal article
EID:

2-s2.0-0028947906

Contributors: Cain, K.; Inayat-Hussain, S.H.; Kokileva, L.; Cohen, G.M.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier

DNA cleavage in rat liver nuclei activated by Mg2+ or Ca2+ + Mg2+ is inhibited by a variety of structurally unrelated inhibitors.

Biochemistry and cell biology = Biochimie et biologie cellulaire
1994 | Journal article
EID:

2-s2.0-0028540297

Contributors: Cain, K.; Inayat-Hussain, S.H.; Kokileva, L.; Cohen, G.M.
Source: Self-asserted source
Salmaan H Inayat-Hussain via Scopus - Elsevier
Items per page:
Page 1 of 2

Peer review (1 review for 1 publication/grant)

Review activity for Genes and environment. (1)