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Atherosclerosis, Plaque stability, macrophages, Inflammation, macrophage immune metabolism, lipid dr
United States

Activities

Employment (3)

The University of Iowa University College: Iowa City, IA, US

2020-08 to 2022-09 | Research Assistant Professor (Internal Medicine)
Employment
Source: Self-asserted source
Prakash Doddapattar

Univesity of Iowa: Iowa city, Iowa, US

2014-07-09 to 2020-08-07 | Postdoctoral Research Scholar (Internal Medicine)
Employment
Source: Self-asserted source
Prakash Doddapattar

Medical University of Graz: Graz, Steiermark, AT

2009 to 2013 | Researcher (Molecular Biology and Biochemistry)
Employment
Source: Self-asserted source
Prakash Doddapattar

Funding (2)

Mechanistic role of pyruvate kinase M2 in atherogenesis

2020-07-01 to 2022-09-02 | Grant
American Heart Association (Dallas, US)
GRANT_NUMBER:

20CDA35310580

Source: check_circle
American Heart Association

Novel role of Integrins in Atherosclerosis

Award
American Heart Association (TX, TX, US)
Source: Self-asserted source
Prakash Doddapattar

Works (28)

Targeting Neutrophil α9 Improves Functional Outcomes After Stroke in Mice With Obesity-Induced Hyperglycemia

Stroke
2023-09 | Journal article
Contributors: Rakesh B. Patel; Nirav Dhanesha; Brijesh Sutariya; Madankumar Ghatge; Prakash Doddapattar; Tarun Barbhuyan; Mariia Kumskova; Enrique C. Leira; Anil K. Chauhan
Source: check_circle
Crossref

Myeloid Cell PKM2 Deletion Enhances Efferocytosis and Reduces Atherosclerosis

Circulation Research
2022-04-29 | Journal article
Contributors: Prakash Doddapattar; Rishabh Dev; Madankumar Ghatge; Rakesh B. Patel; Manish Jain; Nirav Dhanesha; Steven R. Lentz; Anil K. Chauhan
Source: check_circle
Crossref

PKM2 promotes neutrophil activation and cerebral thromboinflammation: therapeutic implications for ischemic stroke

Blood
2022-02-24 | Journal article
Contributors: Nirav Dhanesha; Rakesh B. Patel; Prakash Doddapattar; Madankumar Ghatge; Gagan D. Flora; Manish Jain; Daniel Thedens; Heena Olalde; Mariia Kumskova; Enrique C. Leira et al.
Source: check_circle
Crossref

Integrin α9 regulates smooth muscle cell phenotype switching and vascular remodeling

JCI Insight
2021-05-24 | Journal article
Contributors: Manish Jain; Rishabh Dev; Prakash Doddapattar; Shigeyuki Kon; Nirav Dhanesha; Anil K. Chauhan
Source: check_circle
Crossref

Smooth Muscle Cell–Specific PKM2 (Pyruvate Kinase Muscle 2) Promotes Smooth Muscle Cell Phenotypic Switching and Neointimal Hyperplasia

Arteriosclerosis, Thrombosis, and Vascular Biology
2021-05-05 | Journal article
Contributors: Manish Jain; Nirav Dhanesha; Prakash Doddapattar; Manasa K. Nayak; Liang Guo; Anne Cornelissen; Steven R. Lentz; Aloke V. Finn; Anil K. Chauhan
Source: check_circle
Crossref

Cellular fibronectin promotes deep vein thrombosis in diet-induced obese mice.

Journal of thrombosis and haemostasis : JTH
2020-12-10 | Journal article
Source: Self-asserted source
Prakash Doddapattar

Differential Roles of Endothelial Cell-Derived and Smooth Muscle Cell-Derived Fibronectin Containing Extra Domain A in Early and Late Atherosclerosis.

Arteriosclerosis, thrombosis, and vascular biology
2020-05-21 | Journal article
Source: Self-asserted source
Prakash Doddapattar

Targeting Myeloid-Specific Integrin α9β1 Improves Short- and Long-Term Stroke Outcomes in Murine Models With Preexisting Comorbidities by Limiting Thrombosis and Inflammation.

Circulation research
2020-03-20 | Journal article
Source: Self-asserted source
Prakash Doddapattar

Targeting myeloid-cell specific integrin α9β1 inhibits arterial thrombosis in mice

Blood
2020-03-12 | Journal article
Contributors: Nirav Dhanesha; Manasa K. Nayak; Prakash Doddapattar; Manish Jain; Gagan D. Flora; Shigeyuki Kon; Anil K. Chauhan
Source: check_circle
Crossref

Smooth muscle cell–specific fibronectin-EDA mediates phenotypic switching and neointimal hyperplasia

Journal of Clinical Investigation
2019-11-25 | Journal article
Part of ISSN: 0021-9738
Part of ISSN: 1558-8238
Source: Self-asserted source
Prakash Doddapattar

Dichloroacetate, an inhibitor of pyruvate dehydrogenase kinases, inhibits platelet aggregation and arterial thrombosis.

Blood advances
2018-08 | Journal article
Contributors: Nayak MK; Dhanesha N; Doddapattar P; Rodriguez O; Sonkar VK; Dayal S; Chauhan AK
Source: Self-asserted source
Prakash Doddapattar via Europe PubMed Central

Deletion of Extra Domain A of Fibronectin Reduces Acute Myocardial Ischaemia/Reperfusion Injury in Hyperlipidaemic Mice by Limiting Thrombo-Inflammation.

Thrombosis and haemostasis
2018-06 | Journal article
Contributors: Chorawala MR; Prakash P; Doddapattar P; Jain M; Dhanesha N; Chauhan AK
Source: Self-asserted source
Prakash Doddapattar via Europe PubMed Central

Nutrition and Nutraceuticals in Neuroinflammatory and Brain Metabolic Stress: Implications for Neurodegenerative Disorders.

CNS & neurological disorders drug targets
2018-06 | Journal article
Contributors: Pandareesh MD; Kandikattu HK; Razack S; Narayanappa A; Choudhari R; Vikram A; Doddapattar P
Source: Self-asserted source
Prakash Doddapattar via Europe PubMed Central

Endothelial Cell-Derived Von Willebrand Factor, But Not Platelet-Derived, Promotes Atherosclerosis in Apolipoprotein E-Deficient Mice.

Arteriosclerosis, thrombosis, and vascular biology
2018-01 | Journal article
Contributors: Doddapattar P; Dhanesha N; Chorawala MR; Tinsman C; Jain M; Nayak MK; Staber JM; Chauhan AK
Source: Self-asserted source
Prakash Doddapattar via Europe PubMed Central

Fibronectin Containing Extra Domain A Induces Plaque Destabilization in the Innominate Artery of Aged Apolipoprotein E-Deficient Mice.

Arteriosclerosis, thrombosis, and vascular biology
2018-01 | Journal article
Contributors: Doddapattar P; Jain M; Dhanesha N; Lentz SR; Chauhan AK
Source: Self-asserted source
Prakash Doddapattar via Europe PubMed Central

ADAMTS13 Retards Progression of Diabetic Nephropathy by Inhibiting Intrarenal Thrombosis in Mice.

Arteriosclerosis, thrombosis, and vascular biology
2017-05 | Journal article
Contributors: Dhanesha N; Doddapattar P; Chorawala MR; Nayak MK; Kokame K; Staber JM; Lentz SR; Chauhan AK
Source: Self-asserted source
Prakash Doddapattar via Europe PubMed Central

Endothelial Cell-Derived von Willebrand Factor Is the Major Determinant That Mediates von Willebrand Factor-Dependent Acute Ischemic Stroke by Promoting Postischemic Thrombo-Inflammation.

Arteriosclerosis, thrombosis, and vascular biology
2016-07 | Journal article
Contributors: Dhanesha N; Prakash P; Doddapattar P; Khanna I; Pollpeter MJ; Nayak MK; Staber JM; Chauhan AK
Source: Self-asserted source
Prakash Doddapattar via Europe PubMed Central

Protein methionine oxidation augments reperfusion injury in acute ischemic stroke.

JCI insight
2016-05 | Journal article
Contributors: Gu SX; Blokhin IO; Wilson KM; Dhanesha N; Doddapattar P; Grumbach IM; Chauhan AK; Lentz SR
Source: Self-asserted source
Prakash Doddapattar via Europe PubMed Central

Monoglyceride lipase deficiency modulates endocannabinoid signaling and improves plaque stability in ApoE-knockout mice.

Atherosclerosis
2015-11 | Journal article
Contributors: Vujic N; Schlager S; Eichmann TO; Madreiter-Sokolowski CT; Goeritzer M; Rainer S; Schauer S; Rosenberger A; Woelfler A; Doddapattar P et al.
Source: Self-asserted source
Prakash Doddapattar via Europe PubMed Central

Active autophagy but not lipophagy in macrophages with defective lipolysis

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
2015-10 | Journal article
Contributors: Madeleine Goeritzer; Nemanja Vujic; Stefanie Schlager; Prakash G. Chandak; Melanie Korbelius; Benjamin Gottschalk; Christina Leopold; Sascha Obrowsky; Silvia Rainer; Prakash Doddapattar et al.
Source: check_circle
Crossref

Deletion of Methionine Sulfoxide Reductase A Does Not Affect Atherothrombosis but Promotes Neointimal Hyperplasia and Extracellular Signal-Regulated Kinase 1/2 Signaling.

Arteriosclerosis, thrombosis, and vascular biology
2015-10 | Journal article
Contributors: Klutho PJ; Pennington SM; Scott JA; Wilson KM; Gu SX; Doddapattar P; Xie L; Venema AN; Zhu LJ; Chauhan AK et al.
Source: Self-asserted source
Prakash Doddapattar via Europe PubMed Central

Fibronectin Splicing Variants Containing Extra Domain A Promote Atherosclerosis in Mice Through Toll-Like Receptor 4.

Arteriosclerosis, thrombosis, and vascular biology
2015-10 | Journal article
Contributors: Doddapattar P; Gandhi C; Prakash P; Dhanesha N; Grumbach IM; Dailey ME; Lentz SR; Chauhan AK
Source: Self-asserted source
Prakash Doddapattar via Europe PubMed Central

Genetic Ablation of Extra Domain A of Fibronectin in Hypercholesterolemic Mice Improves Stroke Outcome by Reducing Thrombo-Inflammation.

Circulation
2015-10 | Journal article
Contributors: Dhanesha N; Ahmad A; Prakash P; Doddapattar P; Lentz SR; Chauhan AK
Source: Self-asserted source
Prakash Doddapattar via Europe PubMed Central

Xanthohumol ameliorates atherosclerotic plaque formation, hypercholesterolemia, and hepatic steatosis in ApoE-deficient mice.

Molecular nutrition & food research
2013-05 | Journal article
Contributors: Doddapattar P; Radović B; Patankar JV; Obrowsky S; Jandl K; Nusshold C; Kolb D; Vujić N; Doshi L; Chandak PG et al.
Source: Self-asserted source
Prakash Doddapattar via Europe PubMed Central

Intestinal GATA4 deficiency protects from diet-induced hepatic steatosis.

Journal of hepatology
2012-06 | Journal article
Contributors: Patankar JV; Obrowsky S; Doddapattar P; Hoefler G; Battle M; Levak-Frank S; Kratky D
Source: Self-asserted source
Prakash Doddapattar via Europe PubMed Central

C16 ceramide is crucial for triacylglycerol-induced apoptosis in macrophages.

Cell death & disease
2012-03 | Journal article
Contributors: Aflaki E; Doddapattar P; Radović B; Povoden S; Kolb D; Vujić N; Wegscheider M; Koefeler H; Hornemann T; Graier WF et al.
Source: Self-asserted source
Prakash Doddapattar via Europe PubMed Central

Lack of acyl-CoA:diacylglycerol acyltransferase 1 reduces intestinal cholesterol absorption and attenuates atherosclerosis in apolipoprotein E knockout mice.

Biochimica et biophysica acta
2011-09 | Journal article
Contributors: Chandak PG; Obrowsky S; Radovic B; Doddapattar P; Aflaki E; Kratzer A; Doshi LS; Povoden S; Ahammer H; Hoefler G et al.
Source: Self-asserted source
Prakash Doddapattar via Europe PubMed Central

Endothelial Cell-Derived Von Willebrand Factor, But Not Platelet-Derived, Promotes Atherosclerosis in Apolipoprotein E-Deficient Mice.

ATVB
Journal article
Source: Self-asserted source
Prakash Doddapattar

Peer review (1 review for 1 publication/grant)

Review activity for American Heart Association (1)