Personal information

Emails & domains

Verified email domains

Other IDs

SciProfiles: 3999833

Activities

Collapse all

Employment (1)

University of Washington: Seattle, WA, US

2010-01-01 to present | Professor (Pediatrics and Pathology)
Employment
Source: Self-asserted source
Mark Majesky

Education and qualifications (1)

University of Washington: Seattle, WA, US

1984 to present | Ph.D. (Pharmacology)
Education
Source: Self-asserted source
Mark Majesky

Works (44)

Origins of Aortic Coarctation: A Vascular Smooth Muscle Compartment Boundary Model

2024-12-30 | Preprint
DOI: 10.20944/preprints202412.2407.v1
Contributors: Christina L. Greene; Geoffrey Traeger; Akshay Venkatesh; David Han; Mark W. Majesky
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

KLF4 in smooth muscle cell-derived progenitor cells is essential for angiotensin II-induced cardiac inflammation and fibrosis

2024-06-06 | Preprint
DOI: 10.1101/2024.06.04.597485
Contributors: Sizhao Lu; Austin J Jolly; Allison M Dubner; Keith A Strand; Marie F Mutryn; Tyler Hinthorn; Tysen Noble; Raphael A Nemenoff; Karen S Moulton; Mark W Majesky et al.
Source: check_circle
Crossref

Confounding Effects of Tamoxifen: Cautionary and Practical Considerations for the Use of Tamoxifen-Inducible Mouse Models in Atherosclerosis Research—Brief Report

Arteriosclerosis, Thrombosis, and Vascular Biology
2023-11 | Journal article
DOI: 10.1161/ATVBAHA.123.319922
Contributors: Allison M. Dubner; Sizhao Lu; Austin J. Jolly; Tysen Noble; Tyler Hinthorn; Raphael A. Nemenoff; Karen S. Moulton; Mark W. Majesky; Mary C.M. Weiser-Evans
Source: check_circle
Crossref

Smooth muscle–derived adventitial progenitor cells direct atherosclerotic plaque composition complexity in a Klf4-dependent manner

JCI Insight
2023-11-22 | Journal article
DOI: 10.1172/jci.insight.174639
Contributors: Allison M. Dubner; Sizhao Lu; Austin J. Jolly; Keith A. Strand; Marie F. Mutryn; Tyler Hinthorn; Tysen Noble; Raphael A. Nemenoff; Karen S. Moulton; Mark W. Majesky et al.
Source: check_circle
Crossref

ECM-Focused Proteomic Analysis of Ear Punch Regeneration inAcomys Cahirinus

2023-10-11 | Preprint
DOI: 10.1101/2023.10.11.561940
Contributors: Maxwell C. McCabe; Daryl M. Okamura; Christopher B. Erickson; Blair W. Perry; Chris M. Brewer; Elizabeth D. Nguyen; Anthony J. Saviola; Mark W. Majesky; Kirk C. Hansen
Source: check_circle
Crossref

Mammalian organ regeneration in spiny mice

Journal of Muscle Research and Cell Motility
2023-06 | Journal article
DOI: 10.1007/s10974-022-09631-3
Contributors: Daryl M. Okamura; Elizabeth D. Nguyen; Sarah J. Collins; Kevin Yoon; Joshua B. Gere; Mary C. M. Weiser-Evans; David R. Beier; Mark W. Majesky
Source: check_circle
Crossref

Redistribution of the chromatin remodeler Brg1 directs smooth muscle–derived adventitial progenitor–to–myofibroblast differentiation and vascular fibrosis

JCI Insight
2023-05-08 | Journal article
DOI: 10.1172/jci.insight.164862
Contributors: Austin J. Jolly; Sizhao Lu; Allison M. Dubner; Keith A. Strand; Marie F. Mutryn; Aaron Pilotti-Riley; Etienne P. Danis; Raphael A. Nemenoff; Karen S. Moulton; Mark W. Majesky et al.
Source: check_circle
Crossref

The adventitia in arterial development, remodeling, and hypertension

Biochemical Pharmacology
2022-11 | Journal article
DOI: 10.1016/j.bcp.2022.115259
Contributors: Mark W. Majesky; Mary C.M. Weiser-Evans
Source: check_circle
Crossref

Spiny mice activate unique transcriptional programs after severe kidney injury regenerating organ function without fibrosis.

iScience
2021-11-03 | Journal article
DOI: 10.1016/j.isci.2021.103269
PMID: 34849462
PMC: PMC8609232
Source: Self-asserted source
Mark Majesky

Adaptations in Hippo-Yap signaling and myofibroblast fate underlie scar-free ear appendage wound healing in spiny mice.

Developmental cell
2021-10-04 | Journal article
DOI: 10.1016/j.devcel.2021.09.008
PMID: 34610329
Source: Self-asserted source
Mark Majesky

Fate and State of Vascular Smooth Muscle Cells in Atherosclerosis

Circulation
2021-05-25 | Journal article
DOI: 10.1161/CIRCULATIONAHA.120.049922
Contributors: Joseph M. Miano; Edward A. Fisher; Mark W. Majesky
Source: check_circle
Crossref

Smooth muscle–derived progenitor cell myofibroblast differentiation through KLF4 downregulation promotes arterial remodeling and fibrosis

JCI Insight
2020-12-03 | Journal article
DOI: 10.1172/jci.insight.139445
Contributors: Sizhao Lu; Austin J. Jolly; Keith A. Strand; Allison M. Dubner; Marie F. Mutryn; Karen S. Moulton; Raphael A. Nemenoff; Mark W. Majesky; Mary C.M. Weiser-Evans
Source: check_circle
Crossref

A Tangled Web of Metabolism and Transcription Controls SMC Phenotype.

Circulation research
2020-01-02 | Journal article
DOI: 10.1161/circresaha.119.316281
PMID: 31895665
PMC: PMC7773153
Source: Self-asserted source
Mark Majesky

Origins of Smooth Muscle Progenitor Cells in Transplant Arteriosclerosis.

Circulation research
2019-07-03 | Journal article
DOI: 10.1161/circresaha.119.315379
PMID: 31268852
PMC: PMC6748309
Source: Self-asserted source
Mark Majesky

Lineage tracking of origin and fate of smooth muscle cells in atherosclerosis.

Cardiovascular research
2018-03-01 | Journal article
DOI: 10.1093/cvr/cvx251
PMID: 29293902
PMC: PMC5852531
Source: Self-asserted source
Mark Majesky

Vascular Development.

Arteriosclerosis, thrombosis, and vascular biology
2018-03-01 | Journal article
DOI: 10.1161/atvbaha.118.310223
PMID: 29467221
PMC: PMC5927597
Source: Self-asserted source
Mark Majesky

Branch Point Smooth Muscle Cells Highlighted by Novel Lineage Tracking Approach.

Circulation research
2018-01-01 | Journal article
DOI: 10.1161/circresaha.117.312444
PMID: 29348244
PMC: PMC5782817
Source: Self-asserted source
Mark Majesky

Smooth Muscle Cells Derived From Second Heart Field and Cardiac Neural Crest Reside in Spatially Distinct Domains in the Media of the Ascending Aorta-Brief Report.

Arteriosclerosis, thrombosis, and vascular biology
2017-06-29 | Journal article
DOI: 10.1161/atvbaha.117.309599
PMID: 28663257
PMC: PMC5570666
Source: Self-asserted source
Mark Majesky

Differentiated Smooth Muscle Cells Generate a Subpopulation of Resident Vascular Progenitor Cells in the Adventitia Regulated by Klf4.

Circulation research
2016-11-09 | Journal article
DOI: 10.1161/circresaha.116.309322
PMID: 27834190
PMC: PMC5250562
Source: Self-asserted source
Mark Majesky

Vascular Smooth Muscle Cells.

Arteriosclerosis, thrombosis, and vascular biology
2016-10-01 | Journal article
DOI: 10.1161/atvbaha.116.308261
PMID: 27655780
PMC: PMC5102260
Source: Self-asserted source
Mark Majesky

FOXE3 mutations predispose to thoracic aortic aneurysms and dissections.

The Journal of clinical investigation
2016-02-08 | Journal article
DOI: 10.1172/jci83778
PMID: 26854927
PMC: PMC4767350
Source: Self-asserted source
Mark Majesky

Origin of Matrix-Producing Cells That Contribute to Aortic Fibrosis in Hypertension.

Hypertension (Dallas, Tex. : 1979)
2015-12-22 | Journal article
DOI: 10.1161/hypertensionaha.115.06123
PMID: 26693821
PMC: PMC4713264
Source: Self-asserted source
Mark Majesky

Adventitia and perivascular cells.

Arteriosclerosis, thrombosis, and vascular biology
2015-08-01 | Journal article
DOI: 10.1161/atvbaha.115.306088
PMID: 26203160
PMC: PMC4515770
Source: Self-asserted source
Mark Majesky

Signaling pathways that control rho kinase activity maintain the embryonic epicardial progenitor state.

The Journal of biological chemistry
2015-03-02 | Journal article
DOI: 10.1074/jbc.m114.613190
PMID: 25733666
PMC: PMC4400346
Source: Self-asserted source
Mark Majesky

Pbx4 is Required for the Temporal Onset of Zebrafish Myocardial Differentiation.

Journal of developmental biology
2015-01-01 | Journal article
DOI: 10.3390/jdb3040093
PMID: 26770887
PMC: PMC4709844
Source: Self-asserted source
Mark Majesky

Tbx18 regulates development of the epicardium and coronary vessels.

Developmental biology
2013-09-07 | Journal article
DOI: 10.1016/j.ydbio.2013.08.019
PMID: 24016759
PMC: PMC4172450
Source: Self-asserted source
Mark Majesky

Choosing Smads: smooth muscle origin-specific transforming growth factor-β signaling.

Circulation research
2013-09-01 | Journal article
DOI: 10.1161/circresaha.113.302123
PMID: 24071452
Source: Self-asserted source
Mark Majesky

Coronary adventitial cells are linked to perivascular cardiac fibrosis via TGFβ1 signaling in the mdx mouse model of Duchenne muscular dystrophy.

Journal of molecular and cellular cardiology
2013-08-01 | Journal article
DOI: 10.1016/j.yjmcc.2013.07.014
PMID: 23911435
PMC: PMC3834000
Source: Self-asserted source
Mark Majesky

Interpreting inflammation: smooth muscle positional identity and nuclear factor-κB signaling.

Arteriosclerosis, thrombosis, and vascular biology
2013-06-01 | Journal article
DOI: 10.1161/atvbaha.113.301407
PMID: 23677878
PMC: PMC3748817
Source: Self-asserted source
Mark Majesky

Regulator of G-protein signaling - 5 (RGS5) is a novel repressor of hedgehog signaling.

PloS one
2013-04-18 | Journal article
DOI: 10.1371/journal.pone.0061421
PMID: 23637832
PMC: PMC3630190
Source: Self-asserted source
Mark Majesky

Changing topographic Hox expression in blood vessels results in regionally distinct vessel wall remodeling.

Biology open
2012-03-20 | Journal article
DOI: 10.1242/bio.2012039
PMID: 23213434
PMC: PMC3507213
Source: Self-asserted source
Mark Majesky

Smooth muscle diversity from human pluripotent cells.

Nature biotechnology
2012-02-08 | Journal article
DOI: 10.1038/nbt.2117
PMID: 22318032
PMC: PMC3690307
Source: Self-asserted source
Mark Majesky

Patterning the artery wall by lateral induction of Notch signaling.

Circulation
2011-12-06 | Journal article
DOI: 10.1161/circulationaha.111.075937
PMID: 22147908
PMC: PMC3392127
Source: Self-asserted source
Mark Majesky

Wnt1/βcatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair.

The EMBO journal
2011-11-15 | Journal article
DOI: 10.1038/emboj.2011.418
PMID: 22085926
PMC: PMC3261567
Source: Self-asserted source
Mark Majesky

The adventitia: a progenitor cell niche for the vessel wall.

Cells, tissues, organs
2011-10-14 | Journal article
DOI: 10.1159/000331413
PMID: 22005572
PMC: PMC3257816
Source: Self-asserted source
Mark Majesky

The adventitia: a dynamic interface containing resident progenitor cells.

Arteriosclerosis, thrombosis, and vascular biology
2011-07-01 | Journal article
DOI: 10.1161/atvbaha.110.221549
PMID: 21677296
PMC: PMC3382115
Source: Self-asserted source
Mark Majesky

Parsing aortic aneurysms: more surprises.

Circulation research
2011-03-01 | Journal article
DOI: 10.1161/circresaha.111.240861
PMID: 21372288
PMC: PMC3390159
Source: Self-asserted source
Mark Majesky

Vascular smooth muscle progenitor cells: building and repairing blood vessels.

Circulation research
2011-02-01 | Journal article
DOI: 10.1161/circresaha.110.223800
PMID: 21293008
PMC: PMC3382110
Source: Self-asserted source
Mark Majesky

Neointima formation: a local affair.

Arteriosclerosis, thrombosis, and vascular biology
2010-10-01 | Journal article
DOI: 10.1161/atvbaha.110.211433
PMID: 20844267
PMC: PMC3049730
Source: Self-asserted source
Mark Majesky

Loss of microRNAs in neural crest leads to cardiovascular syndromes resembling human congenital heart defects.

Arteriosclerosis, thrombosis, and vascular biology
2010-09-30 | Journal article
DOI: 10.1161/atvbaha.110.213306
PMID: 20884876
PMC: PMC2988089
Source: Self-asserted source
Mark Majesky

Building a vessel wall with notch signaling.

Circulation research
2009-02-01 | Journal article
DOI: 10.1161/circresaha.109.194233
PMID: 19246684
PMC: PMC2727662
Source: Self-asserted source
Mark Majesky

A sonic hedgehog signaling domain in the arterial adventitia supports resident Sca1+ smooth muscle progenitor cells.

Proceedings of the National Academy of Sciences of the United States of America
2008-06-30 | Journal article
DOI: 10.1073/pnas.0711382105
PMID: 18591670
PMC: PMC2453724
Source: Self-asserted source
Mark Majesky

Chapter 9. Development of coronary vessels.

Methods in enzymology
2008-01-01 | Journal article
DOI: 10.1016/s0076-6879(08)03009-7
PMID: 19022061
Source: Self-asserted source
Mark Majesky

Developmental basis of vascular smooth muscle diversity.

Arteriosclerosis, thrombosis, and vascular biology
2007-03-22 | Journal article
DOI: 10.1161/atvbaha.107.141069
PMID: 17379839
Source: Self-asserted source
Mark Majesky
How many people are using ORCID?