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Activities

Employment (1)

University of Leicester: Leicester, Leicestershire, GB

1999-01-01 to present | Dean of Research (Molecular and Cell Biology)
Employment
Source: Self-asserted source
Andrew Fry

Education and qualifications (2)

University of Oxford: Oxford, Oxfordshire, GB

1989-09-01 to 1993-01-01 | DPhil (Clinical Medicine)
Education
Source: Self-asserted source
Andrew Fry

University of Oxford: Oxford, Oxfordshire, GB

1985-09-01 to 1989-07-31 | BA (Biochemistry)
Education
Source: Self-asserted source
Andrew Fry

Professional activities (1)

Faculty Opinions: London, GB

2009-02-10 to present | Faculty Member
Invited position
Source: check_circle
Faculty Opinions

Funding (21)

A multi-user FACS facility at the University of Leicester

2018-01-01 to 2021-12-31 | Grant
Wellcome Trust (London, GB)
GRANT_NUMBER:

208393/Z/17/Z

Source: Self-asserted source
Andrew Fry via DimensionsWizard

Structural and functional investigations on the consequences of Sam68 post-translational modifications on alternative splicing regulation

2017-12-04 to 2020-12-03 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: BB/R002347/1
Source: Self-asserted source
Andrew Fry via DimensionsWizard

Institutional Strategic Support Fund

2017-01-01 to 2019-12-31 | Grant
Wellcome Trust (London, GB)
GRANT_NUMBER:

204801/Z/16/Z

Source: Self-asserted source
Andrew Fry via DimensionsWizard

Targeting HSP70 to block mitotic progression and centrosome clustering

2016-04-01 to 2019-09-14 | Grant
Worldwide Cancer Research (St Andrews, GB)
GRANT_NUMBER:

WCR-16-0119

Source: Self-asserted source
Andrew Fry via DimensionsWizard

Structural mechanisms of regulation and assembly in the nephronophthisis INVS-NPHP3-NEK8-ANKS6 module

2016-01-01 to 2017-11-01 | Grant
Medical Research Council (London, GB)
GRANT_NUMBER: MR/L017032/2
Source: Self-asserted source
Andrew Fry via DimensionsWizard

A Super-resolution multiphoton and dynamic STORM imaging facility

2015-01-27 to 2016-01-26 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: BB/M012034/1
Source: Self-asserted source
Andrew Fry via DimensionsWizard

Structural mechanisms of regulation and assembly in the nephronophthisis INVS-NPHP3-NEK8-ANKS6 module

2014-07-31 to 2015-12-31 | Grant
Medical Research Council (London, GB)
GRANT_NUMBER: MR/L017032/1
Source: Self-asserted source
Andrew Fry via DimensionsWizard

EML proteins in microtubule regulation, cell division and cancer

2013-04-01 to 2016-03-30 | Grant
Worldwide Cancer Research (St Andrews, GB)
GRANT_NUMBER:

WCR-13-0042

Source: Self-asserted source
Andrew Fry via DimensionsWizard

Central Research Facility.

2010-06-11 to 2013-11-10 | Grant
Wellcome Trust (London, GB)
GRANT_NUMBER:

085999/Z/08/Z

Source: Self-asserted source
Andrew Fry via DimensionsWizard

Investigating Pix protein function in microtubule-related processes

2008-09-30 to 2012-03-30 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: BB/F010702/1
Source: Self-asserted source
Andrew Fry via DimensionsWizard

NIMA-related kinases in cell cycle control and human disease.

2007-10-01 to 2013-09-30 | Grant
Wellcome Trust (London, GB)
GRANT_NUMBER:

082828/Z/07/Z

Source: Self-asserted source
Andrew Fry via DimensionsWizard

Identification and validation of Nek2 kinase inhibitors: hit to lead development

2006-12-01 to 2008-01-31 | Grant
Cancer Research UK (London, GB)
GRANT_NUMBER:

CRUK-A7820

Source: Self-asserted source
Andrew Fry via DimensionsWizard

Regulation of protein destruction in mitosis.

2006-04-01 to 2010-12-31 | Grant
Worldwide Cancer Research (St Andrews, GB)
GRANT_NUMBER:

WCR-06-0029

Source: Self-asserted source
Andrew Fry via DimensionsWizard

Confocal imaging of intracellular protein dynamics.

2005-11-01 to 2008-10-31 | Grant
Wellcome Trust (London, GB)
GRANT_NUMBER:

078020/Z/05/Z

Source: Self-asserted source
Andrew Fry via DimensionsWizard

OFD1, a centrosomal protein mutated in human polcystic kidney disease: an investigation of its role in kidney growth and differentiation.

2005-04-18 to 2008-04-17 | Grant
Wellcome Trust (London, GB)
GRANT_NUMBER:

075311/Z/04/Z

Source: Self-asserted source
Andrew Fry via DimensionsWizard

Delta vision digital imaging fluorescence microscope system

2005-01-01 to 2006-12-31 | Grant
Wellcome Trust (London, GB)
GRANT_NUMBER:

060514/Z/00/B

Source: Self-asserted source
Andrew Fry via DimensionsWizard

Examining the role of the Nek6, Nek7 and Nek9 protein kinases in cell cycle progression and spindle assembly in Xenopus laevis.

2004-11-01 to 2007-10-31 | Grant
Wellcome Trust (London, GB)
GRANT_NUMBER:

075269/Z/04/Z

Source: Self-asserted source
Andrew Fry via DimensionsWizard

Investigating the roles of C-Nap1 and Nek2 in centrosome organization.

2003-01-01 to 2007-09-30 | Grant
Wellcome Trust (London, GB)
GRANT_NUMBER:

069035/Z/02/Z

Source: Self-asserted source
Andrew Fry via DimensionsWizard

Delta vision digital imaging fluroescence microscope system.

2001-06-01 to 2004-12-31 | Grant
Wellcome Trust (London, GB)
GRANT_NUMBER:

060514/Z/00/A

Source: Self-asserted source
Andrew Fry via DimensionsWizard

Delta vision digital imaging fluorescence microscope system.

2001-06-01 to 2004-05-31 | Grant
Wellcome Trust (London, GB)
GRANT_NUMBER:

060514/Z/00/Z

Source: Self-asserted source
Andrew Fry via DimensionsWizard

Cell cycle control: Elucidation of the function of a potential human nimA protein kinase homolog.

1993-10-01 to 1994-09-30 | Grant
Swiss National Science Foundation (Bern, CH)
GRANT_NUMBER: 38928
Source: Self-asserted source
Andrew Fry via DimensionsWizard

Works (50 of 74)

Items per page:
Page 1 of 2

Endogenous oncogenic KRAS expression increases cell proliferation and motility in near-diploid hTERT RPE-1 cells

2023-09-08 | Preprint
Contributors: Naushin L. Hindul; Lauren R. Abbott; Sumaya M.D. Adan; Kornelis R. Straatman; Andrew M. Fry; Kouji Hirota; Kayoko Tanaka
Source: check_circle
Crossref

Data from EML4-ALK Variant 3 Promotes Mitotic Errors and Spindle Assembly Checkpoint Deficiency Leading to Increased Microtubule Poison Sensitivity

2023-04-03 | Preprint
Contributors: Kellie Lucken; Laura O'Regan; Jene Choi; Josephina Sampson; Sarah L. Pashley; Richard Bayliss; Sam Khan; Andrew M. Fry
Source: check_circle
Crossref

Data from EML4-ALK Variant 3 Promotes Mitotic Errors and Spindle Assembly Checkpoint Deficiency Leading to Increased Microtubule Poison Sensitivity

2023-04-03 | Preprint
Contributors: Kellie Lucken; Laura O'Regan; Jene Choi; Josephina Sampson; Sarah L. Pashley; Richard Bayliss; Sam Khan; Andrew M. Fry
Source: check_circle
Crossref

Supplementary Figure from EML4-ALK Variant 3 Promotes Mitotic Errors and Spindle Assembly Checkpoint Deficiency Leading to Increased Microtubule Poison Sensitivity

2023-04-03 | Preprint
Contributors: Kellie Lucken; Laura O'Regan; Jene Choi; Josephina Sampson; Sarah L. Pashley; Richard Bayliss; Sam Khan; Andrew M. Fry
Source: check_circle
Crossref

Supplementary Figure from EML4-ALK Variant 3 Promotes Mitotic Errors and Spindle Assembly Checkpoint Deficiency Leading to Increased Microtubule Poison Sensitivity

2023-04-03 | Preprint
Contributors: Kellie Lucken; Laura O'Regan; Jene Choi; Josephina Sampson; Sarah L. Pashley; Richard Bayliss; Sam Khan; Andrew M. Fry
Source: check_circle
Crossref

BAP1 loss induces mitotic defects in mesothelioma cells through BRCA1-dependent and independent mechanisms

2022-08-04 | Preprint
Contributors: Andrew Fry; Anita Singh; Sara Busacca; Aarti Gaba; Michael Sheaff; Charlotte Poile; Apostolos Nakas; Joanna Dzialo; Aleksandra Bzura; Alan Dawson et al.
Source: check_circle
Crossref

Alternative Treatment Options to ALK Inhibitor Monotherapy for EML4-ALK-Driven Lung Cancer

Cancers
2022-07-15 | Journal article
Contributors: Savvas Papageorgiou; Sarah L. Pashley; Laura O’Regan; Sam Khan; Richard Bayliss; Andrew M. Fry
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

EML4-ALK Variant 3 Promotes Mitotic Errors and Spindle Assembly Checkpoint Deficiency Leading to Increased Microtubule Poison Sensitivity

Molecular Cancer Research
2022-06-03 | Journal article
Contributors: Kellie Lucken; Laura O'Regan; Jene Choi; Josephina Sampson; Sarah L. Pashley; Richard Bayliss; Sam Khan; Andrew M. Fry
Source: check_circle
Crossref

Construction of a human hTERT RPE-1 cell line with inducible Cre for editing of endogenous genes

Biology Open
2022-02-15 | Journal article
Contributors: Naushin L. Hindul; Amarjot Jhita; Daiana G. Oprea; Tasnim Alamgir Hussain; Oksana Gonchar; Miguel Angel Muro Campillo; Laura O'Regan; Masato T. Kanemaki; Andrew M. Fry; Kouji Hirota et al.
Source: check_circle
Crossref

Phase‐separated foci of EML4‐ALK facilitate signalling and depend upon an active kinase conformation

EMBO reports
2021-12-06 | Journal article
Contributors: Josephina Sampson; Mark W Richards; Jene Choi; Andrew M Fry; Richard Bayliss
Source: check_circle
Crossref

2-Arylamino-6-ethynylpurines are cysteine-targeting irreversible inhibitors of Nek2 kinase

RSC Medicinal Chemistry
2020 | Journal article
Contributors: Christopher J. Matheson; Christopher R. Coxon; Richard Bayliss; Kathy Boxall; Benoit Carbain; Andrew M. Fry; Ian R. Hardcastle; Suzannah J. Harnor; Corine Mas-Droux; David R. Newell et al.
Source: check_circle
Crossref

Phase-separation of EML4-ALK variant 3 is dependent upon an active ALK conformation

2020-06-11 | Preprint
Contributors: Josephina Sampson; Mark W. Richards; Jene Choi; Andrew M. Fry; Richard Bayliss
Source: check_circle
Crossref

Nek11

Encyclopedia of Signaling Molecules
2018 | Other
Part of ISBN: 9783319671987
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Nek2

Encyclopedia of Signaling Molecules
2018 | Other
Part of ISBN: 9783319671987
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Nek6

Encyclopedia of Signaling Molecules
2018 | Other
Part of ISBN: 9783319671987
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Nek7

Encyclopedia of Signaling Molecules
2018 | Other
Part of ISBN: 9783319671987
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Nek8

Encyclopedia of Signaling Molecules
2018 | Other
Part of ISBN: 9783319671987
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Nek9/Nercc1

Encyclopedia of Signaling Molecules
2018 | Other
Part of ISBN: 9783319671987
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Mitotic phosphorylation by Nek6 and Nek7 reduces microtubule affinity of EML4 to alter spindle dynamics and promote chromosome congression

2018-11-09 | Other
Contributors: Andrew M. Fry; Rozita Adib; Jessica M Montgomery; Joseph Atherton; Laura O'Regan; Mark Richards; Kees R Straatman; Daniel Roth; Anne Straube; Richard Bayliss et al.
Source: check_circle
Crossref

Mitotic phosphorylation regulates Hsp72 spindle localization by uncoupling ATP binding from substrate release

Science Signaling
2018-08-14 | Journal article
Contributors: Manjeet Mukherjee; Sarah Sabir; Laura O’Regan; Josephina Sampson; Mark W. Richards; Nicolas Huguenin-Dezot; James R. Ault; Jason W. Chin; Anastasia Zhuravleva; Andrew M. Fry et al.
Source: check_circle
Crossref

Mitotic Regulation by NEK Kinase Networks

Frontiers in Cell and Developmental Biology
2017 | Journal article
Part of ISSN: 2296-634X
Contributors: Andrew M. Fry; Richard Bayliss; Joan Roig
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Nek2

Encyclopedia of Cancer
2017 | Other
Part of ISBN: 9783662468746
Contributors: Andrew M. Fry
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Quantum counting: Operator methods for discrete population dynamics with applications to cell division

Progress in Biophysics and Molecular Biology
2017-11 | Journal article
Contributors: T.R. Robinson; E. Haven; A.M. Fry
Source: check_circle
Crossref

Faculty of 1000 evaluation for A mechanism for the elimination of the female gamete centrosome in Drosophila melanogaster.

F1000 - Post-publication peer review of the biomedical literature
2017-08 | Dataset
Contributors: Andrew Fry
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Faculty of 1000 evaluation for Centrosomes. Regulated assembly of a supramolecular centrosome scaffold in vitro.

F1000 - Post-publication peer review of the biomedical literature
2017-08 | Dataset
Contributors: Andrew Fry
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Faculty of 1000 evaluation for Dishevelled is a NEK2 kinase substrate controlling dynamics of centrosomal linker proteins.

F1000 - Post-publication peer review of the biomedical literature
2017-08 | Dataset
Contributors: Andrew Fry
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Faculty of 1000 evaluation for Nuclear alignment in myotubes requires centrosome proteins recruited by nesprin-1.

F1000 - Post-publication peer review of the biomedical literature
2017-08 | Dataset
Contributors: Andrew Fry
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Faculty of 1000 evaluation for SPD-2/CEP192 and CDK Are Limiting for Microtubule-Organizing Center Function at the Centrosome.

F1000 - Post-publication peer review of the biomedical literature
2017-08 | Dataset
Contributors: Andrew Fry
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Faculty of 1000 evaluation for Structural basis for mitotic centrosome assembly in flies.

F1000 - Post-publication peer review of the biomedical literature
2017-08 | Dataset
Contributors: Andrew Fry
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Faculty of 1000 evaluation for The Centrosome Is a Selective Condensate that Nucleates Microtubules by Concentrating Tubulin.

F1000 - Post-publication peer review of the biomedical literature
2017-08 | Dataset
Contributors: Andrew Fry
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Recent advances in pericentriolar material organization: ordered layers and scaffolding gels

F1000Research
2017-08-31 | Journal article
Contributors: Andrew M. Fry; Josephina Sampson; Caroline Shak; Sue Shackleton
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Hsp72 and Nek6 Cooperate to Cluster Amplified Centrosomes in Cancer Cells

Cancer Research
2017-07 | Journal article
Part of ISSN: 0008-5472
Contributors: Josephina Sampson; Laura O'Regan; Martin J.S. Dyer; Richard Bayliss; Andrew M. Fry
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Molecular mechanisms that underpin EML4-ALK driven cancers and their response to targeted drugs

Cellular and Molecular Life Sciences
2016-01-11 | Journal article
Part of ISSN: 1420-682X
Contributors: Richard Bayliss; Jene Choi; Dean A. Fennell; Andrew M. Fry; Mark W. Richards
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Nek2

Encyclopedia of Cancer
2015 | Other
Part of ISBN: 9783642278419
Contributors: Andrew M. Fry
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Mechanistic basis of Nek7 activation through Nek9 binding and induced dimerization

Nature Communications
2015-11-02 | Journal article
Part of ISSN: 2041-1723
Contributors: Tamanna Haq; Mark W. Richards; Selena G. Burgess; Pablo Gallego; Sharon Yeoh; Laura O’Regan; David Reverter; Joan Roig; Andrew M. Fry; Richard Bayliss
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Loss of Nek11 Prevents G2/M Arrest and Promotes Cell Death in HCT116 Colorectal Cancer Cells Exposed to Therapeutic DNA Damaging Agents

PLOS ONE
2015-10 | Journal article
Part of ISSN: 1932-6203
Contributors: Sarah R. Sabir; Navdeep K. Sahota; George D. D. Jones; Andrew M. Fry; Claude Prigent
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Faculty of 1000 evaluation for Nek2 activation of Kif24 ensures cilium disassembly during the cell cycle.

F1000 - Post-publication peer review of the biomedical literature
2015-09-02 | Dataset
Contributors: Andrew Fry
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Nek5: a new regulator of centrosome integrity

Oncotarget
2015-08-11 | Journal article
Part of ISSN: 1949-2553
Contributors: Suzanna L. Prosser; Andrew M. Fry
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Novel insights into the mechanisms of mitotic spindle assembly by NEK kinases

Molecular & Cellular Oncology
2015-07-06 | Journal article
Part of ISSN: 2372-3556
Contributors: Suzanna L. Prosser; Laura O'Regan; Andrew M. Fry
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Nek5 promotes centrosome integrity in interphase and loss of centrosome cohesion in mitosis

The Journal of Cell Biology
2015-05-11 | Journal article
Part of ISSN: 0021-9525
Contributors: Suzanna L. Prosser; Navdeep K. Sahota; Laurence Pelletier; Ciaran G. Morrison; Andrew M. Fry
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Hsp72 is targeted to the mitotic spindle by Nek6 to promote K-fiber assembly and mitotic progression

The Journal of Cell Biology
2015-05-04 | Journal article
Part of ISSN: 0021-9525
Contributors: Laura O’Regan; Josephina Sampson; Mark W. Richards; Axel Knebel; Daniel Roth; Fiona E. Hood; Anne Straube; Stephen J. Royle; Richard Bayliss; Andrew M. Fry
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Faculty of 1000 evaluation for Stabilization of Cartwheel-less Centrioles for Duplication Requires CEP295-Mediated Centriole-to-Centrosome Conversion.

F1000 - Post-publication peer review of the biomedical literature
2014-08 | Dataset
Contributors: Andrew Fry
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Overexpression of the Nek2 kinase in colorectal cancer correlates with beta-catenin relocalization and shortened cancer-specific survival

Journal of Surgical Oncology
2014-07 | Journal article
Part of ISSN: 0022-4790
Contributors: Christopher P. Neal; Andrew M. Fry; Catherine Moreman; Angus McGregor; Giuseppe Garcea; David P. Berry; Margaret M. Manson
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Faculty of 1000 evaluation for Proximity Interactions among Centrosome Components Identify Regulators of Centriole Duplication.

F1000 - Post-publication peer review of the biomedical literature
2014-03 | Dataset
Contributors: Andrew Fry
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Faculty of 1000 evaluation for NEK2 induces drug resistance mainly through activation of efflux drug pumps and is associated with poor prognosis in myeloma and other cancers.

F1000 - Post-publication peer review of the biomedical literature
2013-01 | Dataset
Contributors: Andrew Fry
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Regulation of the Centrosome Cycle by Protein Degradation

The Centrosome
2012 | Other
Part of ISBN: 9781627030342
Contributors: Suzanna L. Prosser; Andrew M. Fry
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Cell cycle regulation by the NEK family of protein kinases

Journal of Cell Science
2012-10-01 | Journal article
Part of ISSN: 0021-9533
Contributors: A. M. Fry; L. O'Regan; S. R. Sabir; R. Bayliss
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Faculty of 1000 evaluation for The S. pombe cytokinesis NDR kinase Sid2 activates Fin1 NIMA kinase to control mitotic commitment through Pom1/Wee1.

F1000 - Post-publication peer review of the biomedical literature
2012-07 | Dataset
Contributors: Andrew Fry
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

Nek2

Encyclopedia of Cancer
2011 | Other
Part of ISBN: 9783642164828
Contributors: Andrew M. Fry
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search

The Nek8 protein kinase, mutated in the human cystic kidney disease nephronophthisis, is both activated and degraded during ciliogenesis

Human Molecular Genetics
2011-11 | Journal article
Part of ISSN: 1460-2083
Contributors: Detina Zalli; Richard Bayliss; Andrew M. Fry
Source: Self-asserted source
Andrew Fry via Crossref Metadata Search
Items per page:
Page 1 of 2

Peer review (3 reviews for 2 publications/grants)

Review activity for Drug resistance updates. (1)
Review activity for Faculty Opinions (2)