Biography

Sigrid A. Langhans, PhD, Principal Research Scientist, is Head of the Cancer Epigenetics Laboratory and Director of the Nemours High-Throughput Screening (HTS) & Drug Discovery Laboratory at Nemours Children’s Health. Dr. Langhans is also an Affiliated Professor in the Department of Materials Science and Engineering at the University of Delaware, an affiliated faculty in the Department of Biological Sciences at the University of Delaware, and a Research Assistant Professor in the Department of Pediatrics at Thomas Jefferson University. Dr. Langhans earned her doctorate in physiology and biophysics from the Weill Medical College of Cornell University and was a post-doctoral fellow in tumor biology at the University of California, Los Angeles (UCLA). Her research focuses on molecular studies on signaling networks in cerebellar granule cell development and function and the relationship between neuronal development and cancer in the brain. Dr. Langhans’ development of a comprehensive pediatric neuro-oncology research program at Nemours further encompasses collaborative research with the University of Delaware to develop a high-throughput screening (HTS)-compatible 3D cell culture platform for drug discovery, and together with the Nemours PET Imaging Center, a clinically translatable PET imaging approach for pediatric brain tumors. Her research is supported by the Nemours Foundation, American Cancer Society, National Institutes of Health, and the D.O. Believe Foundation.