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Image Processing, Structural Biology, Cryo-EM, Single-particle cryo-EM, Biochemistry , Cryo-ET, Subtomogram averaging, NMR, Fungi, Amyloid, Taxonomy
France, Spain

Biography

In September 2022, I joined The Carazo and Sorzano Lab in the capacity of a postdoctoral researcher working in cryo-ET-focussed image processing.


Previous scientific experience:

From 2020-2022, I was a Postdoctoral Fellow at The Hanein lab working on Cryo-electron Microscopy (cryo-EM). We used this technique to determine three-dimensional structures of macromolecular assemblies in a fully hydrated state and in cellula. I am specialized Cryo-Electron Tomography (cryo-ET) that can give insight into these complexes in cells or tissues. Also, I am the lab member specialized in cryo-EM/ET image processing analysis.

In 2016, I obtained a place on the Pasteur-Paris University International Doctoral Program (Marie Sklodowska-Curie grant No. 665807) and joined the group of Iñaki Guijarro (Biological NMR Technological Platform). During my PhD, I worked on the structural and characterization of Functional Amyloids from the fungal pathogen Aspergillus fumigatus.

In 2015, I did an internship at the Biological Research Center in Madrid, where I began working in the field of Nuclear Magnetic Resonance (NMR) with a project related to molecular recognition and chemical glycobiology.

From 2010 to 2014 I studied a bachelor’s degree in Biology at the Complutense University of Madrid. During my thesis research project, I worked on the bioremediation of phenolic groups in industrial oil fractions degraded by ligninolytic fungi. Following this, I completed my Master’s degree in Microbiology gaining experience in Molecular Biology and Biochemistry while working on biodegradation of oil by higher fungi.

Activities

Employment (3)

National Center for Biotechnology: Madrid, ES

2022-09 to present | Postdoctoral researcher (Macromolecular Structures )
Employment
Source: Self-asserted source
Borja Rodriguez de Francisco

Institut Pasteur: Paris, FR

2020 to 2022 | Postdoctoral researcher (Structural Biology and Chemistry)
Employment
Source: Self-asserted source
Borja Rodriguez de Francisco

Institut Pasteur: Paris, FR

2016 to 2019 | PhD student (Structural Biology and Chemistry )
Employment
Source: Self-asserted source
Borja Rodriguez de Francisco

Education and qualifications (4)

Sorbonne Université Campus Pierre et Marie Curie: Paris, FR

2016 to 2019 | PhD student
Qualification
Source: Self-asserted source
Borja Rodriguez de Francisco

Institut Pasteur: Paris, FR

2016 to 2019 | PhD in Structural Biology and Biochemistry
Education
Source: Self-asserted source
Borja Rodriguez de Francisco

Autonomous University of Madrid: Madrid, ES

2014 to 2015 | Master's in Microbiology
Education
Source: Self-asserted source
Borja Rodriguez de Francisco

Autonomous University of Madrid: Madrid, ES

2010 to 2014 | Degree in Biology
Education
Source: Self-asserted source
Borja Rodriguez de Francisco

Professional activities (2)

Society of Spanish Researchers in France: Paris, FR

2018-05 to present | Active member (Paris region delegation)
Membership
Source: Self-asserted source
Borja Rodriguez de Francisco

Iberian Mycological Society : Madrid, ES

2017-01 to present | Member of the Scientific Committee
Membership
Source: Self-asserted source
Borja Rodriguez de Francisco

Funding (1)

Marie Sklodowska-Curie PhD Fellowship

2016 to 2019 | Contract
Institut Pasteur (Paris, FR)
Source: Self-asserted source
Borja Rodriguez de Francisco

Works (9)

Scipion3: A workflow engine for cryo-electron microscopy image processing and structural biology

Biological Imaging
2023 | Journal article
Part of ISSN: 2633-903X
Contributors: Pablo Conesa Mingo; Yunior C. Fonseca; Jorge Jiménez de la Morena; Grigory Sharov; Jose Miguel de la Rosa-Trevín; Ana Cuervo; Alberto García Mena; Borja Rodríguez de Francisco; Daniel del Hoyo; David Herreros et al.
Source: Self-asserted source
Borja Rodriguez de Francisco

MEPSi: A tool for simulating tomograms of membrane-embedded proteins

Journal of Structural Biology
2022-12 | Journal article
Part of ISSN: 1047-8477
Contributors: Borja Rodríguez de Francisco; Armel Bezault; Xiao-Ping Xu; Dorit Hanein; Niels Volkmann
Source: Self-asserted source
Borja Rodriguez de Francisco

Characterization of heterogeneity in nanodisc samples using Feret signatures

2022-07 | Preprint
Contributors: Vilela F; Bezault A; de Francisco BR; Sauvanet C; Xu X; Swift MF; Yao Y; Marrasi FM; Hanein D; Volkmann N
Source: Self-asserted source
Borja Rodriguez de Francisco via Europe PubMed Central

Fluorinated Carbohydrates as Lectin Ligands: Simultaneous Screening of a Monosaccharide Library and Chemical Mapping by 19F NMR Spectroscopy

The Journal of Organic Chemistry
2020-12-18 | Journal article
Contributors: J. Daniel Martínez; Ana I. Manzano; Eva Calviño; Ana de Diego; Borja Rodriguez de Francisco; Cecilia Romanò; Stefan Oscarson; Oscar Millet; Hans-Joachim Gabius; Jesús Jiménez-Barbero et al.
Source: check_circle
Crossref

The Role of RodA-Conserved Cysteine Residues in the Aspergillus fumigatus Conidial Surface Organization

Journal of Fungi
2020-08-26 | Journal article
Contributors: Isabel Valsecchi; Emmanuel Stephen-Victor; Sarah Sze Wah Wong; Anupama Karnam; Margaret Sunde; J. Iñaki Guijarro; Borja Rodríguez de Francisco; Thomas Krüger; Olaf Kniemeyer; Gordon D. Brown et al.
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

Approach to the mycological catalogue of the Dehesa of Somosierra and new records for the Community of Madrid (Spain)

Botanica Complutensis
2019-10-02 | Journal article
Contributors: Jesús Palá-Paúl; Borja Rodríguez de Francisco; Adrián Lázaro-Lobo
Source: check_circle
Crossref

Probing Structural Changes during Self-assembly of Surface-Active Hydrophobin Proteins that Form Functional Amyloids in Fungi

Journal of Molecular Biology
2018 | Journal article
Source: Self-asserted source
Borja Rodriguez de Francisco
grade
Preferred source (of 2)‎

Approach to the floristic catalogue of the Dehesa of Somosierra and new records for the Community of Madrid (Spain)

Botanica Complutensis
2017-11-16 | Journal article
Part of ISSN: 1988-2874
Part of ISSN: 0214-4565
Source: Self-asserted source
Borja Rodriguez de Francisco

Coprinopsis xenobia, description and first locations in Spain. Genetic comparison with Coprinopsis luteocephala

Boletín Micológico de FAMCAL
2013-10-10 | Journal article
Part of ISSN: 1886-5984
Source: Self-asserted source
Borja Rodriguez de Francisco