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Scopus Author ID: 23973419500

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United States, Germany, Pakistan, United Arab Emirates

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Employment (1)

Khalifa University of Science and Technology: Abu Dhabi, AE

2023-06-01 to present | Assistant Professor (Biological Sciences, College of Medicine and Health Sciences)
Employment
Source: Self-asserted source
Muhammad Farooq Rai

Education and qualifications (1)

Freie Universitat Berlin: Berlin, Berlin, DE

2008 | Ph.D. (Immunology and Molecular Biology)
Education
Source: Self-asserted source
Muhammad Farooq Rai

Professional activities (1)

Faculty Opinions: London, GB

2017-10-23 to present | Faculty Member
Invited position
Source: check_circle
Faculty Opinions

Works (50 of 73)

Items per page:
Page 1 of 2

Appraising the evolving landscape of protease inhibition in osteoarthritis

Nature Reviews Rheumatology
2025-03 | Journal article
DOI: 10.1038/s41584-024-01198-2
Contributors: Muhammad Farooq Rai
Source: check_circle
Crossref

Loss of periostin function impairs ligament fibroblast activity and facilitates ROS‐mediated cellular senescence

The FASEB Journal
2024-08-31 | Journal article
DOI: 10.1096/fj.202302615RR
Contributors: Muhammad Farooq Rai; Xin Duan; Mingming Yan; Robert H. Brophy; Lei Cai
Source: check_circle
Crossref

Distinct patterns of cytokines, chemokines, and growth factors in synovial fluid after ACL injury in comparison to osteoarthritis

Journal of Orthopaedic Research
2024-07 | Journal article
DOI: 10.1002/jor.25794
Contributors: Muhammad Farooq Rai; Lei Cai; Nobuaki Chinzei; Eric J. Schmidt; Omer Yousuf; Farshid Guilak; Robert H. Brophy
Source: check_circle
Crossref

Three decades of advancements in osteoarthritis research: insights from transcriptomic, proteomic, and metabolomic studies

Osteoarthritis and Cartilage
2024-04 | Journal article
DOI: 10.1016/j.joca.2023.11.019
Contributors: Muhammad Farooq Rai; Kelsey H. Collins; Annemarie Lang; Tristan Maerz; Jeroen Geurts; Cristina Ruiz-Romero; Ronald K. June; Yolande Ramos; Sarah J. Rice; Shabana Amanda Ali et al.
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Crossref

Osteoarthritis year in review 2023: genetics, genomics, and epigenetics

Osteoarthritis and Cartilage
2024-02 | Journal article
DOI: 10.1016/j.joca.2023.11.006
Contributors: Amina Waheed; Muhammad Farooq Rai
Source: check_circle
Crossref

Gene Expression in Glenoid Articular Cartilage Varies Across Acute Instability, Chronic Instability, and Osteoarthritis

Journal of Bone and Joint Surgery
2023-07-05 | Journal article
DOI: 10.2106/JBJS.22.01124
Contributors: Alexander W. Aleem; Muhammad Farooq Rai; Lei Cai; Robert H. Brophy
Source: check_circle
Crossref

Synovial Fluid Proteomics From Serial Aspirations of ACL-Injured Knees Identifies Candidate Biomarkers

The American Journal of Sports Medicine
2023-06 | Journal article
DOI: 10.1177/03635465231169526
Contributors: Muhammad Farooq Rai; Lei Cai; Qiang Zhang; R. Reid Townsend; Robert H. Brophy
Source: check_circle
Crossref

Reply to the Letter to the Editor

Journal of Orthopaedic Research
2022-12 | Journal article
DOI: 10.1002/jor.25461
Contributors: Muhammad Farooq Rai; Eric D. Tycksen; Jay Keener
Source: check_circle
Crossref

RNA‐Seq analysis reveals sex‐dependent transcriptomic profiles of human subacromial bursa stratified by tear etiology

Journal of Orthopaedic Research
2022-12 | Journal article
DOI: 10.1002/jor.25316
Contributors: Muhammad Farooq Rai; Lei Cai; Eric D. Tycksen; Aaron Chamberlain; Jay Keener
Source: check_circle
Crossref

RNA‐Seq reveals distinct transcriptomic differences in rotator cuff tendon based on tear etiology and patient sex

Journal of Orthopaedic Research
2022-12 | Journal article
DOI: 10.1002/jor.25296
Contributors: Muhammad Farooq Rai; Lei Cai; Eric D. Tycksen; Jay Keener; Aaron Chamberlain
Source: check_circle
Crossref

Proteomic Profile Analysis of Synovial Fluid in Patients With Anterior Cruciate Ligament Tears

The American Journal of Sports Medicine
2022-09 | Journal article
DOI: 10.1177/03635465221112652
Contributors: Robert H. Brophy; Lei Cai; Qiang Zhang; R. Reid Townsend; Muhammad Farooq Rai
Source: check_circle
Crossref

Glutamine metabolism modulates chondrocyte inflammatory response

eLife
2022-08-02 | Journal article
DOI: 10.7554/eLife.80725
Contributors: Manoj Arra; Gaurav Swarnkar; Naga Suresh Adapala; Syeda Kanwal Naqvi; Lei Cai; Muhammad Farooq Rai; Srikanth Singamaneni; Gabriel Mbalaviele; Robert Brophy; Yousef Abu-Amer
Source: check_circle
Crossref

Glutamine metabolism modulates chondrocyte inflammatory response

2022-06-09 | Preprint
DOI: 10.1101/2022.06.09.495504
Contributors: Manoj Arra; Gaurav Swarnkar; Naga Suresh Adapala; Syeda Kanwal Naqvi; Lei Cai; Farooq Rai; Gabriel Mbalaviele; Robert Brophy; Yousef Abu-Amer
Source: check_circle
Crossref

Novel mechanistic role of Kif26b in adipogenic differentiation of murine multipotent stromal cells

Biochemical and Biophysical Research Communications
2022-02 | Journal article
DOI: 10.1016/j.bbrc.2021.12.067
Contributors: Mingming Yan; Lei Cai; Xin Duan; Muhammad Farooq Rai
Source: check_circle
Crossref

Amelioration of Posttraumatic Osteoarthritis in Mice Using Intraarticular Silencing of Periostin via Nanoparticle‐Based Small Interfering RNA

Arthritis & Rheumatology
2021-12 | Journal article
DOI: 10.1002/art.41794
Contributors: Xin Duan; Lei Cai; Christine T. N. Pham; Yousef Abu‐Amer; Hua Pan; Robert H. Brophy; Samuel A. Wickline; Muhammad Farooq Rai
Source: check_circle
Crossref

Back to basics: Transcriptomics studies for deep phenotyping of osteoarthritis

Osteoarthritis and Cartilage Open
2021-12 | Journal article
DOI: 10.1016/j.ocarto.2021.100166
Contributors: Muhammad Farooq Rai
Source: check_circle
Crossref

Periostin loss-of-function protects mice from post-traumatic and age-related osteoarthritis

Arthritis Research & Therapy
2021-12 | Journal article
DOI: 10.1186/s13075-021-02477-z
Contributors: Mukundan Attur; Xin Duan; Lei Cai; Tianzhen Han; Weili Zhang; Eric D. Tycksen; Jonathan Samuels; Robert H. Brophy; Steven B. Abramson; Muhammad Farooq Rai
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Crossref

Radiographic and Clinical Evidence for Osteoarthritis at Medium-Term Follow-up after Arthroscopic Partial Medial Meniscectomy

CARTILAGE
2021-12 | Journal article
DOI: 10.1177/1947603519892315
Contributors: Joseph D. Lamplot; William P. Tompkins; Michael V. Friedman; Joseph T. Nguyen; Muhammad Farooq Rai; Robert H. Brophy
Source: check_circle
Crossref

Nip it in the bud: potential for the early treatment of osteoarthritis

Osteoarthritis and Cartilage
2021-01 | Journal article
DOI: 10.1016/j.joca.2020.09.003
Contributors: M.F. Rai
Source: check_circle
Crossref

KIF26B Silencing Prevents Osseous Transdifferentiation of Progenitor/Stem Cells and Attenuates Ectopic Calcification in a Murine Model

Journal of Bone and Mineral Research
2020-12-01 | Journal article
DOI: 10.1002/jbmr.4473
Contributors: Mingming Yan; Xin Duan; Lei Cai; Weili Zhang; Matthew J Silva; Robert H Brophy; Muhammad Farooq Rai
Source: check_circle
Crossref

A Microarray Study of Articular Cartilage in Relation to Obesity and Severity of Knee Osteoarthritis

CARTILAGE
2020-10 | Journal article
DOI: 10.1177/1947603518796122
Contributors: Muhammad Farooq Rai; Linda J. Sandell; Toby N. Barrack; Lei Cai; Eric D. Tycksen; Simon Y. Tang; Matthew J. Silva; Robert L. Barrack
Source: check_circle
Crossref

Molecular biology of meniscus pathology: Lessons learned from translational studies and mouse models

Journal of Orthopaedic Research
2020-09 | Journal article
DOI: 10.1002/jor.24630
Contributors: Muhammad Farooq Rai; Robert H. Brophy; Vicki Rosen
Source: check_circle
Crossref

Genetic correlations between cartilage regeneration and degeneration reveal an inverse relationship

Osteoarthritis and Cartilage
2020-08 | Journal article
DOI: 10.1016/j.joca.2020.04.013
Contributors: M.F. Rai; J.M. Cheverud; E.J. Schmidt; L.J. Sandell
Source: check_circle
Crossref

Micro-Clotting of Platelet-Rich Plasma Upon Loading in Hydrogel Microspheres Leads to Prolonged Protein Release and Slower Microsphere Degradation

Polymers
2020-07-30 | Journal article
DOI: 10.3390/polym12081712
Contributors: Miran Hannah Choi; Alexandra Blanco; Samuel Stealey; Xin Duan; Natasha Case; Scott Allen Sell; Muhammad Farooq Rai; Silviya Petrova Zustiak
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Crossref
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LDHA-mediated ROS generation in chondrocytes is a potential therapeutic target for osteoarthritis

Nature Communications
2020-07-09 | Journal article
DOI: 10.1038/s41467-020-17242-0
Contributors: Manoj Arra; Gaurav Swarnkar; Ke Ke; Jesse E. Otero; Jun Ying; Xin Duan; Takashi Maruyama; Muhammad Farooq Rai; Regis J. O’Keefe; Gabriel Mbalaviele et al.
Source: check_circle
Crossref

Duration of symptoms prior to partial meniscectomy is not associated with the expression of osteoarthritis genes in the injured meniscus

Journal of Orthopaedic Research
2020-06 | Journal article
DOI: 10.1002/jor.24574
Contributors: Robert H. Brophy; Eric J. Schmidt; Lei Cai; Muhammad Farooq Rai
Source: check_circle
Crossref

RNA-seq analysis of chondrocyte transcriptome reveals genetic heterogeneity in LG/J and SM/J murine strains

Osteoarthritis and Cartilage
2020-04 | Journal article
DOI: 10.1016/j.joca.2020.01.001
Contributors: X. Duan; L. Cai; E.J. Schmidt; J. Shen; E.D. Tycksen; R.J. O'Keefe; J.M. Cheverud; M.F. Rai
Source: check_circle
Crossref

Induction of WNT16 via Peptide-mRNA Nanoparticle-Based Delivery Maintains Cartilage Homeostasis

Pharmaceutics
2020-01-17 | Journal article
DOI: 10.3390/pharmaceutics12010073
Contributors: Huimin Yan; Ying Hu; Antonina Akk; Muhammad Farooq Rai; Hua Pan; Samuel A. Wickline; Christine T.N. Pham
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Crossref
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Applications of RNA interference in the treatment of arthritis

Translational Research
2019-12 | Journal article
DOI: 10.1016/j.trsl.2019.07.002
Contributors: Muhammad Farooq Rai; Hua Pan; Huimin Yan; Linda J. Sandell; Christine T.N. Pham; Samuel A. Wickline
Source: check_circle
Crossref

Proteomic analysis of synovial fluid identifies periostin as a biomarker for anterior cruciate ligament injury

Osteoarthritis and Cartilage
2019-12 | Journal article
DOI: 10.1016/j.joca.2019.08.002
Contributors: R.H. Brophy; L. Cai; X. Duan; Q. Zhang; R.R. Townsend; R.M. Nunley; F. Guilak; M.F. Rai
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Crossref

Platelet‐Rich Plasma Released From Polyethylene Glycol Hydrogels Exerts Beneficial Effects on Human Chondrocytes

Journal of Orthopaedic Research
2019-11 | Journal article
DOI: 10.1002/jor.24404
Contributors: Era Jain; Nobuaki Chinzei; Alexandra Blanco; Natasha Case; Linda J. Sandell; Scott Sell; Muhammad Farooq Rai; Silviya P. Zustiak
Source: check_circle
Crossref

Distinct degenerative phenotype of articular cartilage from knees with meniscus tear compared to knees with osteoarthritis

Osteoarthritis and Cartilage
2019-06 | Journal article
DOI: 10.1016/j.joca.2019.02.792
Contributors: M.F. Rai; E.D. Tycksen; L. Cai; J. Yu; R.W. Wright; R.H. Brophy
Source: check_circle
Crossref

Evidence for Genetic Contribution to Variation in Posttraumatic Osteoarthritis in Mice

Arthritis & Rheumatology
2019-03 | Journal article
DOI: 10.1002/art.40730
Contributors: Nobuaki Chinzei; Muhammad Farooq Rai; Shingo Hashimoto; Eric J. Schmidt; Ken Takebe; James M. Cheverud; Linda J. Sandell
Source: check_circle
Crossref

Development of a peptide-siRNA nanocomplex targeting NF- κB for efficient cartilage delivery

Scientific Reports
2019-01-24 | Journal article
DOI: 10.1038/s41598-018-37018-3
Contributors: Huimin Yan; Xin Duan; Hua Pan; Antonina Akk; Linda J. Sandell; Samuel A. Wickline; Muhammad Farooq Rai; Christine T. N. Pham
Source: check_circle
Crossref

Presence of meniscus tear alters gene expression profile of anterior cruciate ligament tears

Journal of Orthopaedic Research
2018-10 | Journal article
DOI: 10.1002/jor.24025
Contributors: Robert H. Brophy; Marcus A. Rothermich; Eric D. Tycksen; Lei Cai; Muhammad Farooq Rai
Source: check_circle
Crossref

Early onset of disc degeneration in SM/J mice is associated with changes in ion transport systems and fibrotic events

Matrix Biology
2018-09 | Journal article
DOI: 10.1016/j.matbio.2018.03.024
Contributors: Ying Zhang; Chi Xiong; Mateusz Kudelko; Yan Li; Cheng Wang; Yuk Lun Wong; Vivian Tam; Muhammad Farooq Rai; James Cheverud; Heather A. Lawson et al.
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Crossref

Canine hip dysplasia: A natural animal model for human developmental dysplasia of the hip

Journal of Orthopaedic Research
2018-07 | Journal article
DOI: 10.1002/jor.23828
Contributors: Cecilia Pascual‐Garrido; Farshid Guilak; M. Farooq Rai; Michael D. Harris; Mandi J. Lopez; Rory J. Todhunter; John C. Clohisy
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Crossref

Molecular influence of anterior cruciate ligament tear remnants on chondrocytes: a biologic connection between injury and osteoarthritis

Osteoarthritis and Cartilage
2018-04 | Journal article
DOI: 10.1016/j.joca.2018.01.017
Contributors: N. Chinzei; R.H. Brophy; X. Duan; L. Cai; R.M. Nunley; L.J. Sandell; M.F. Rai
Source: check_circle
Crossref

Transcriptome comparison of meniscus from patients with and without osteoarthritis

Osteoarthritis and Cartilage
2018-03 | Journal article
DOI: 10.1016/j.joca.2017.12.004
Contributors: R.H. Brophy; B. Zhang; L. Cai; R.W. Wright; L.J. Sandell; M.F. Rai
Source: check_circle
Crossref

Advantages of RNA‐seq compared to RNA microarrays for transcriptome profiling of anterior cruciate ligament tears

Journal of Orthopaedic Research
2018-01 | Journal article
DOI: 10.1002/jor.23661
Contributors: Muhammad Farooq Rai; Eric D. Tycksen; Linda J. Sandell; Robert H. Brophy
Source: check_circle
Crossref

Early changes in the knee of healer and non-healer mice following non-invasive mechanical injury

Journal of Orthopaedic Research
2017 | Journal article
DOI: 10.1002/jor.23413
EID:

2-s2.0-84987916944
Contributors: Duan, X.; Rai, M.F.; Holguin, N.; Silva, M.J.; Patra, D.; Liao, W.; Sandell, L.J.
Source: Self-asserted source
Muhammad Farooq Rai via Scopus - Elsevier

Traumatic and Degenerative Meniscus Tears Have Different Gene Expression Signatures

American Journal of Sports Medicine
2017 | Journal article
DOI: 10.1177/0363546516664889
EID:

2-s2.0-85008439752
Contributors: Brophy, R.H.; Sandell, L.J.; Rai, M.F.
Source: Self-asserted source
Muhammad Farooq Rai via Scopus - Elsevier

Therapeutic efficacy of intra-articular hyaluronan derivative and platelet-rich plasma in mice following axial tibial loading

PLOS ONE
2017-04-13 | Journal article
DOI: 10.1371/journal.pone.0175682
Contributors: Xin Duan; Hani A. Awad; Linda J. Sandell; Nobuaki Chinzei; Nilsson Holguin; Matthew J. Silva; Antonella Schiavinato; Muhammad Farooq Rai
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Crossref

Changes in Transcriptome-Wide Gene Expression of Anterior Cruciate Ligament Tears Based on Time from Injury

American Journal of Sports Medicine
2016 | Journal article
DOI: 10.1177/0363546516643810
EID:

2-s2.0-84982867350
Contributors: Brophy, R.H.; Tycksen, E.D.; Sandell, L.J.; Rai, M.F.
Source: Self-asserted source
Muhammad Farooq Rai via Scopus - Elsevier

Gene expression in human meniscal tears has limited association with early degenerative changes in knee articular cartilage

Connective Tissue Research
2016 | Journal article
DOI: 10.1080/03008207.2016.1211114
EID:

2-s2.0-84981736117
Contributors: Brophy, R.H.; Sandell, L.J.; Cheverud, J.M.; Rai, M.F.
Source: Self-asserted source
Muhammad Farooq Rai via Scopus - Elsevier

Suppression of NF-κB activity via nanoparticle-based siRNA delivery alters early cartilage responses to injury

Proceedings of the National Academy of Sciences of the United States of America
2016 | Journal article
DOI: 10.1073/pnas.1608245113
EID:

2-s2.0-84991517844
Contributors: Yan, H.; Duan, X.; Pan, H.; Holguin, N.; Rai, M.F.; Akk, A.; Springer, L.E.; Wickline, S.A.; Sandell, L.J.; Pham, C.T.N.
Source: Self-asserted source
Muhammad Farooq Rai via Scopus - Elsevier

RNA Microarray Analysis of Macroscopically Normal Articular Cartilage from Knees Undergoing Partial Medial Meniscectomy: Potential Prediction of the Risk for Developing Osteoarthritis

PLOS ONE
2016-05-12 | Journal article
DOI: 10.1371/journal.pone.0155373
Contributors: Muhammad Farooq Rai; Joseph Najbauer; Linda J. Sandell; Bo Zhang; Rick W. Wright; Robert H. Brophy
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Crossref
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Preferred source (of 2)‎

Emerging Concepts in Gene Therapy for Osteoarthritis

Journal of the American Academy of Orthopaedic Surgeons
2015 | Journal article
DOI: 10.5435/JAAOS-D-15-00339
EID:

2-s2.0-84942573951
Contributors: Rai, M.F.; Sandell, L.J.
Source: Self-asserted source
Muhammad Farooq Rai via Scopus - Elsevier

Genetic loci that regulate ectopic calcification in response to knee trauma in LG/J by SM/J advanced intercross mice

Journal of Orthopaedic Research
2015 | Journal article
DOI: 10.1002/jor.22944
EID:

2-s2.0-84940459119
Contributors: Rai, M.F.; Schmidt, E.J.; Hashimoto, S.; Cheverud, J.M.; Sandell, L.J.
Source: Self-asserted source
Muhammad Farooq Rai via Scopus - Elsevier

Genetic Variability in the Response to Injury

Post-Traumatic Arthritis
2015 | Other
DOI: 10.1007/978-1-4899-7606-2_13
Contributors: Muhammad Farooq Rai; Linda J. Sandell
Source: Self-asserted source
Muhammad Farooq Rai via Crossref Metadata Search
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Items per page:
Page 1 of 2

Peer review (63 reviews for 22 publications/grants)

Review activity for Advanced science. (1)
Review activity for Arthritis & rheumatology. (1)
Review activity for Arthritis research & therapy. (2)
Review activity for Bioscience reports. (1)
Review activity for BMC veterinary research (1)
Review activity for Communications biology. (1)
Review activity for Communications medicine. (1)
Review activity for Connective tissue research. (6)
Review activity for Faculty Opinions (14)
Review activity for Gene. (1)
Review activity for Heliyon. (2)
Review activity for Journal of Advanced Research (1)
Review activity for Journal of experimental orthopaedics. (2)
Review activity for Journal of orthopaedic research. (4)
Review activity for Lab animal. (1)
Review activity for Matrix biology. (3)
Review activity for Molecular and cellular biochemistry. (1)
Review activity for Osteoarthritis and cartilage (11)
Review activity for Osteoarthritis and cartilage open. (5)
Review activity for PloS one. (2)
Review activity for Stem cell research & therapy. (1)
Review activity for Tissue & cell. (1)
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