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Biochemistry, Molecular Biology, Cell Biology, DNA repair, Genomic/Genetic Instability, DNA damage, AAV production, Baculovirus production
Italy

Biography

• January 2023 – to date: post doc position at University of Florence, Health Sciences Department
• September 2021 – August 2022: as GMP Specialist at InnovaVector, Pozzuoli thanks to my expertise in writing and reviewing scientific protocols, I had the role to write SOPs and MBRs important for the Production Area of the GMP. Moreover, thanks to my knowledges on AAV viral vector production, I performed several experiments and studies that were finally useful to achieve strong economic benefits for the company and to have an improve in the yield and quality of the final product.
• January 2017 – December 2019: as PhD student at the Institute of Biology of Valrose in Nice, I was involved in project regarding the retina and transcription factor Otx2. Molecular and Biochemical Techniques from my background were fundamental for the project management. An invitation to an international meeting of specialists, a scientific publication and some awards were the major benefits the laboratory and I achieved thanks to these investigations.

• December 2015 - December 2016: as owner of a fellowship in the laboratory of F. M. Pisani at the Institute of Protein Biochemistry, in Naples, I was involved in a DNA repair and Sister Chromatid Cohesion mechanisms – related project. My expertise and the capacity to organize a collaboration with other researchers were strongly useful to achieve a scientific publication. These studies are now well cited by other researchers and were useful for the laboratory to get new funds. Obtained data were also presented in Intercontinental and National Meetings, giving to the laboratory new opportunities to trace collaborations.

• December 2014 – November 2015: as voluntary trainee in the laboratory of G. C. Bellenchi at the Institute of Genetics and Biophysics Adriano Buzzati Traverso , in Naples, I participated to a project regarding the role of microRNAs on dopaminergic neurons development and organization in midbrain. Thanks to my Molecular Biology background, I had the role to produce new single guide RNAs by cloning strategies and new variants of Cas 9 gene by mutagenesis with the goal to knock out specific miRNA genes in midbrain dopaminergic neurons at specific stages, in vitro and then in vivo

• March 2014 – November 2014: trainee in the clinical laboratory of Polydiagnostic Center Ascione & Panella s.r.l., Torre del Greco (Naples) Training objective(s): to learn and carry out routine clinical analyses

• May 2012 – July 2013: Under-graduate student in the laboratory of E. Biffali at the “Stazione Zoologica A. Dohrn”, Naples
Project objective(s): to characterize the expression pattern of several genes involved in sensory organs pigmentation during embryonic development of Ascidian models

• September 2009 – March 2010: undergraduate student (Bachelor’s degree) in the laboratory of D. Fulgione at the University Federico II, Naples Project objective(s): to investigate on the phylogenetic relationships in Rana lessonae complex by molecular approaches

Activities

Employment (5)

Università degli Studi di Firenze Dipartimento di Biologia: Firenze, Toscana, IT

2023-01-01 to present | Assegnista postdoc (Scienze della Salute)
Employment
Source: Self-asserted source
PASQUALE PENSIERI

Innovavector Srl: Pozzuoli, Napoli, IT

2021-09-01 to 2022-08-31 | GMP Specialist
Employment
Source: Self-asserted source
PASQUALE PENSIERI

Nice Sophia Antipolis University: Nice, FR

2017-01-01 to 2019-12-01 | dottorando (Istituto Biologia Valrose)
Employment
Source: Self-asserted source
PASQUALE PENSIERI

Istituto di Biochimica e Biologia Cellulare Consiglio Nazionale delle Ricerche: Naples, CAMPANIA, IT

2015-12-01 to 2016-12-30 | Borsista (Lab. Pisani)
Employment
Source: Self-asserted source
PASQUALE PENSIERI

Istituto di Genetica e Biofisica Adriano Buzzati Traverso: Napoli, Campania, IT

2014-12-01 to 2015-11-01 | Tirocinante volontario (Lab. Bellenchi )
Employment
Source: Self-asserted source
PASQUALE PENSIERI

Education and qualifications (3)

Nice Sophia Antipolis University: Nice, FR

2017-01-01 to 2019-12-31 | Dottorato (Istituto di Biologia Valrose)
Education
Source: Self-asserted source
PASQUALE PENSIERI

Università degli Studi di Napoli Federico II Dipartimento di Biologia: Napoli, Campania, IT

2010-09-01 to 2013-07-22 | Laurea Magistrale in Biologia
Education
Source: Self-asserted source
PASQUALE PENSIERI

Università degli Studi di Napoli Federico II Dipartimento di Biologia: Napoli, Campania, IT

2006-09-01 to 2010-03-26 | Laurea Triennale in Biologia Generale ed Applicata (Biologia)
Education
Source: Self-asserted source
PASQUALE PENSIERI

Works (5)

Schwann cell TRPA1 ortholog in zebrafish larvae mediates chemotherapy-induced peripheral neuropathy

British Journal of Pharmacology
2024-07-09 | Journal article
Contributors: PASQUALE PENSIERI; Matilde Marini; Francesco De Logu; Romina Nassini; Gaetano De Siena; Martina Chieca; Irene Scuffi; Alessandra Mastricci
Source: Self-asserted source
PASQUALE PENSIERI

Aromatase inhibitors evoke periorbital allodynia in mice via calcitonin gene-related peptide and its receptors in Schwann cells

Confinia Cephalalgica
2024-06-18 | Journal article
Part of ISSN: 1122-0279
Contributors: Matilde Marini; Araújo, DSM; Souza Monteiro de Araújo, D; Souza Monteiro de Araujo, D; Martina Chieca; Elisa Bellantoni; Gaetano De Siena; Alessandra Mastricci; Irene Scuffi; Martina Tesi; Pasquale Pensieri; Romina Nassini et al.
Source: Self-asserted source
PASQUALE PENSIERI

Schwann Cell C5aR1 co-opts Inflammasome NLRP1 to Sustain Pain in a Mouse Model of Endometriosis

Nat. Comm.
2024-04-15 | Preprint
Contributors: Francesco De Logu; Mustafa Titiz; Lorenzo Landini; Araújo, DSM; Souza Monteiro de Araújo, D; Souza Monteiro de Araujo, D; MARINI MATILDE; Viola Seravalli; Martina Chieca; Pasquale Pensieri; Marco Montini; Gaetano De Siena et al.
Source: Self-asserted source
PASQUALE PENSIERI

Photoreceptor cKO of OTX2 Enhances OTX2 Intercellular Transfer in the Retina and Causes Photophobia.

eNeuro
2021-09-01 | Journal article
Contributors: Pensieri P; Mantilleri A; Plassard D; Takahisa Furukawa; Kenneth Moya; Alain Prochiantz; Lamonerie T
Source: Self-asserted source
PASQUALE PENSIERI

Interaction of the Warsaw breakage syndrome DNA helicase DDX11 with the replication fork-protection factor Timeless promotes sister chromatid cohesion.

PLoS genetics
2018-10-10 | Journal article
Contributors: Cortone G; Zheng G; Pensieri P; Chiappetta V; Tatè R; Malacaria E; Pichierri P; Hongtao Yu; Francesca M. Pisani
Source: Self-asserted source
PASQUALE PENSIERI