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Scopus Author ID: 56525654600

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Wuhan University: Wuhan, Hubei, CN

2018-12-01 to present | Assistant professor (Medical Research Institute)
Employment
Source: Self-asserted source
Youngnam Jin

Works (27)

Calcium levels in ASER neurons determine behavioral valence by engaging distinct neuronal circuits in C. elegans

Nature Communications
2025-02-20 | Journal article
DOI: 10.1038/s41467-025-57051-x
Contributors: Weikang Xue; Yuanhua Chen; Ziyi Lei; Yuanxia Wang; Jiaze Liu; Xin Wen; Fang Xu; Pu Chen; Zhengxing Wu; Youngnam N. Jin et al.
Source: check_circle
Crossref

Non-canonical translation in cancer: significance and therapeutic potential of non-canonical ORFs, m6A-modification, and circular RNAs

Cell Death Discovery
2024-09-27 | Journal article
DOI: 10.1038/s41420-024-02185-y
Contributors: Xiaoyi Deng; Yanxun V. Yu; Youngnam N. Jin
Source: check_circle
Crossref

Regulation of lifespan and proteostasis by sensory neural activity and CaMK

Research Square
2023 | Other
DOI: 10.21203/rs.3.rs-3266506
EID:

2-s2.0-85170500769
Contributors: Yu, Y.V.; Zhao, R.; Ge, W.; Xue, W.; Liu, J.; Wang, K.; Jin, Y.N.
Source: Self-asserted source
Youngnam Jin via Scopus - Elsevier

Chemical Genetics: Manipulating the Germline with Small Molecules

Methods in Molecular Biology
2021 | Book chapter
DOI: 10.1007/978-1-0716-0970-5_6
EID:

2-s2.0-85102030104

Part of ISSN: 19406029 10643745
Contributors: Jin, Y.N.; Peterson, R.T.
Source: Self-asserted source
Youngnam Jin via Scopus - Elsevier

Noncanonical translation via deadenylated 3′ UTRs maintains primordial germ cells

Nature Chemical Biology
2018 | Journal article
DOI: 10.1038/s41589-018-0098-0
EID:

2-s2.0-85049618175

Part of ISSN: 15524469 15524450
Contributors: Jin, Y.N.; Schlueter, P.J.; Jurisch-Yaksi, N.; Lam, P.-Y.; Jin, S.; Hwang, W.Y.; Yeh, J.-R.J.; Yoshigi, M.; Ong, S.-E.; Schenone, M. et al.
Source: Self-asserted source
Youngnam Jin via Scopus - Elsevier

Pharmacological HIF2α inhibition improves VHL disease-associated phenotypes in zebrafish model

Journal of Clinical Investigation
2015 | Journal article
DOI: 10.1172/JCI73665
EID:

2-s2.0-84929008961

Part of ISSN: 15588238 00219738
Contributors: Metelo, A.M.; Noonan, H.R.; Xiang, L.; Jin, Y.; Baker, R.; Kamentsky, L.; Zhang, Y.; Van Rooijen, E.; Shin, J.; Carpenter, A.E. et al.
Source: Self-asserted source
Youngnam Jin via Scopus - Elsevier

PTPMT1 inhibition lowers glucose through succinate dehydrogenase phosphorylation

Cell Reports
2015 | Journal article
DOI: 10.1016/j.celrep.2015.01.010
EID:

2-s2.0-84923345116

Part of ISSN: 22111247
Contributors: Nath, A.K.; Ryu, J.H.; Jin, Y.N.; Roberts, L.D.; Dejam, A.; Gerszten, R.E.; Peterson, R.T.
Source: Self-asserted source
Youngnam Jin via Scopus - Elsevier

Nrf2 reduces levels of phosphorylated tau protein by inducing autophagy adaptor protein NDP52.

Nature communications
2014-03-25 | Journal article
DOI: 10.1038/ncomms4496
PMID: 24667209
PMC: PMC3990284
Contributors: Jo C; Gundemir S; Pritchard S; Jin YN; Rahman I; Johnson GV
Source: Self-asserted source
Youngnam Jin
grade
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Photochemical activation of TRPA1 channels in neurons and animals

Nature Chemical Biology
2013 | Journal article
DOI: 10.1038/nchembio.1183
EID:

2-s2.0-84875457497

Part of ISSN: 15524450 15524469
Contributors: Kokel, D.; Cheung, C.Y.J.; Mills, R.; Coutinho-Budd, J.; Huang, L.; Setola, V.; Sprague, J.; Jin, S.; Jin, Y.N.; Huang, X.-P. et al.
Source: Self-asserted source
Youngnam Jin via Scopus - Elsevier

Mitochondrial permeability transition pore induces mitochondria injury in Huntington disease.

Molecular neurodegeneration
2013-12-11 | Journal article
DOI: 10.1186/1750-1326-8-45
PMID: 24330821
PMC: PMC3878840
Contributors: Rodrigo Quintanilla; Jin YN; Rommy von Bernhardi; Johnson GV
Source: Self-asserted source
Youngnam Jin
grade
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Impaired mitochondrial dynamics and Nrf2 signaling contribute to compromised responses to oxidative stress in striatal cells expressing full-length mutant huntingtin.

PloS one
2013-03-01 | Journal article
DOI: 10.1371/journal.pone.0057932
PMID: 23469253
PMC: PMC3585875
Contributors: Jin YN; Yanxun Yu; Gundemir S; Jo C; Cui M; Tieu K; Johnson GV
Source: Self-asserted source
Youngnam Jin
grade
Preferred source (of 2)‎

Usp14 deficiency increases tau phosphorylation without altering tau degradation or causing tau-dependent deficits.

PloS one
2012-10-29 | Journal article
DOI: 10.1371/journal.pone.0047884
PMID: 23144711
PMC: PMC3483306
Contributors: Jin YN; Chen PC; Watson JA; Brandon Walters; Phillips SE; Green K; Schmidt R; Wilson JA; Johnson GV; Erik Roberson et al.
Source: Self-asserted source
Youngnam Jin
grade
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An in vivo zebrafish screen identifies organophosphate antidotes with diverse mechanisms of action.

Journal of biomolecular screening
2012-09-06 | Journal article
DOI: 10.1177/1087057112458153
PMID: 22960781
PMC: PMC4053346
Contributors: Jin S; Sarkar KS; Jin YN; Liu Y; Kokel D; Tjakko van Ham; Lee D Roberts; Gerszten RE; Macrae CA; Randall Peterson
Source: Self-asserted source
Youngnam Jin
grade
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Metabolic state determines sensitivity to cellular stress in Huntington disease: normalization by activation of PPARγ.

PloS one
2012-01-20 | Journal article
DOI: 10.1371/journal.pone.0030406
PMID: 22276192
PMC: PMC3262812
Contributors: Jin YN; Hwang WY; Jo C; Johnson GV
Source: Self-asserted source
Youngnam Jin
grade
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Decreases in valosin-containing protein result in increased levels of tau phosphorylated at Ser262/356.

FEBS letters
2011-10-05 | Journal article
DOI: 10.1016/j.febslet.2011.09.032
PMID: 21983102
PMC: PMC3209510
Contributors: Dolan PJ; Jin YN; Hwang W; Johnson GV
Source: Self-asserted source
Youngnam Jin
grade
Preferred source (of 2)‎

Truncated tau and Aβ cooperatively impair mitochondria in primary neurons.

Neurobiology of aging
2011-03-29 | Journal article
DOI: 10.1016/j.neurobiolaging.2011.02.007
PMID: 21450370
PMC: PMC3140623
Contributors: Rodrigo Quintanilla; Dolan PJ; Jin YN; Johnson GV
Source: Self-asserted source
Youngnam Jin
grade
Preferred source (of 2)‎

The interrelationship between mitochondrial dysfunction and transcriptional dysregulation in Huntington disease.

Journal of bioenergetics and biomembranes
2010-06-01 | Journal article
DOI: 10.1007/s10863-010-9286-7
PMID: 20556492
PMC: PMC2913874
Contributors: Jin YN; Johnson GV
Source: Self-asserted source
Youngnam Jin
grade
Preferred source (of 2)‎

Excretory-secretory products from Paragonimus westermani increase nitric oxide production in microglia in PKC-dependent and -independent manners.

Neuroscience research
2009-06-17 | Journal article
DOI: 10.1016/j.neures.2009.06.006
PMID: 19539668
Contributors: Jin Y; Choi IY; Kim C; Hong S; Kim WK
Source: Self-asserted source
Youngnam Jin
grade
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Rosiglitazone treatment prevents mitochondrial dysfunction in mutant huntingtin-expressing cells: possible role of peroxisome proliferator-activated receptor-gamma (PPARgamma) in the pathogenesis of Huntington disease.

The Journal of biological chemistry
2008-07-18 | Journal article
DOI: 10.1074/jbc.m804291200
PMID: 18640979
PMC: PMC2533094
Contributors: Rodrigo Quintanilla; Jin YN; Fuenzalida K; Bronfman M; Johnson GVW
Source: Self-asserted source
Youngnam Jin
grade
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Doxorubicin binds to un-phosphorylated form of hNopp140 and reduces protein kinase CK2-dependent phosphorylation of hNopp140.

Journal of biochemistry and molecular biology
2006-11-01 | Journal article
DOI: 10.5483/bmbrep.2006.39.6.774
PMID: 17129415
Contributors: Kim YK; Lee WK; Jin Y; Lee KJ; Jeon H; Yu YG
Source: Self-asserted source
Youngnam Jin
grade
Preferred source (of 2)‎

Transgenic rescue of ataxia mice with neuronal-specific expression of ubiquitin-specific protease 14.

The Journal of neuroscience : the official journal of the Society for Neuroscience
2006-11-01 | Journal article
DOI: 10.1523/jneurosci.3600-06.2006
PMID: 17079671
PMC: PMC6674543
Contributors: Crimmins S; Jin Y; Wheeler C; Huffman AK; Chapman C; Lynn E. Dobrunz; Levey A; Kevin Roth; Wilson JA; Wilson SM
Source: Self-asserted source
Youngnam Jin

Excretory-secretory products produced by paragonimus westermani differentially regulate the nitric oxide production and viability of microglial cells.

International archives of allergy and immunology
2005-11-02 | Journal article
DOI: 10.1159/000089518
PMID: 16272822
Contributors: Jin Y; Lee JC; Choi IY; Kim EA; Myeong Heon Shin; Kim WK
Source: Self-asserted source
Youngnam Jin
grade
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Ciclopirox protects mitochondria from hydrogen peroxide toxicity.

British journal of pharmacology
2005-06-01 | Journal article
DOI: 10.1038/sj.bjp.0706206
PMID: 15806112
PMC: PMC1576158
Contributors: Lee SJ; Jin Y; Yoon HY; Choi BO; Kim HC; Yu-Kyoung Oh; Kim HS; Kim WK
Source: Self-asserted source
Youngnam Jin

Erratum: Blockade of peroxynitrite-mediated astrocyte death by manganese(III)-cyclam (Neuroscience Research (2003) 45 (157-161) PII: S0168010202002067)

Neuroscience Research
2003 | Journal article
DOI: 10.1016/S0168-0102(03)00118-4
EID:

2-s2.0-0037828512

Part of ISSN: 01680102
Contributors: Choi, I.Y.; Jin, Y.; Nam, W.; Kim, H.-C.; Kim, W.-K.
Source: Self-asserted source
Youngnam Jin via Scopus - Elsevier

Purification and characterization of human nucleolar phosphoprotein 140 expressed in Escherichia coli.

Protein expression and purification
2003-10-01 | Journal article
DOI: 10.1016/s1046-5928(03)00194-3
PMID: 14550645
Contributors: Kim YK; Jin Y; Vukoti KM; Park JK; Kim EE; Kong-Joo Lee; Yu YG
Source: Self-asserted source
Youngnam Jin
grade
Preferred source (of 2)‎

Blockade of peroxynitrite-mediated astrocyte death by manganese(III)-cyclam.

Neuroscience research
2003-02-01 | Journal article
DOI: 10.1016/s0168-0102(02)00206-7
PMID: 12573462
Contributors: Choi Y; Jin Y; Wonwoo Nam; Kim HC; Kim WK
Source: Self-asserted source
Youngnam Jin
grade
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Identification of hNopp140 as a binding partner for doxorubicin with a phage display cloning method.

Chemistry & biology
2002-02-01 | Journal article
DOI: 10.1016/s1074-5521(02)00096-0
PMID: 11880030
Contributors: Jin Y; Yu J; Yu YG
Source: Self-asserted source
Youngnam Jin
grade
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